Reactome | UniProt:P31946 YWHAB

UniProt:P31946 YWHAB

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

1433B_HUMAN, A8K9K2, E1P616

List of interactors in Reactome

Interactors (92)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.955	38
P49815	3	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548)	0.945	15
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.919	15
P15056	3	BRAF [cytosol] (R-HSA-167224) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S446,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679)	0.905	11
P30305	3	CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734) p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644)	0.894	8
P46937	8	p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y407-YAP1 [cytosol] (R-HSA-9865208) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.894	9
P30307	8	CDC25C [cytosol] (R-HSA-157879) CDC25C [nucleoplasm] (R-HSA-69741) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-S198-CDC25C [cytosol] (R-HSA-8981697) p-S198-CDC25C [nucleoplasm] (R-HSA-156668) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654)	0.886	8
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.869	10
P40818	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.867	9
Q02241	2	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695)	0.867	8
P26045	2	PTPN3 [cytosol] (R-HSA-8867650) PTPN3 [plasma membrane] (R-HSA-5490317)	0.859	8
Q6PKG0	1	LARP1 [cytosol] (R-HSA-9760421)	0.826	8
Q9Y4H2	1	IRS2 [cytosol] (R-HSA-57528)	0.826	7
Q9UBF8	1	PI4KB [cytosol] (R-HSA-1604615)	0.813	6
Q92934	4	BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297) p-S99-BAD [cytosol] (R-HSA-198335)	0.798	6
P30291	3	p-S53-WEE1 [nucleoplasm] (R-HSA-156694) p-WEE1 [nucleoplasm] (R-HSA-156491) WEE1 [nucleoplasm] (R-HSA-69253)	0.796	5
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.788	5
Q02750	4	MAP2K1 [cytosol] (R-HSA-59502) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.788	7
O43524	11	Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841849) FOXO3 [cytosol] (R-HSA-5687032) FOXO3 [nucleoplasm] (R-HSA-199305) FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841824) p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289)	0.774	6
P56524	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.774	6
Q9H0H5	1	RACGAP1 [cytosol] (R-HSA-195122)	0.758	4
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.75	5
O00443	1	PIK3C2A [cytosol] (R-HSA-1604624)	0.745	6
Q86TI0	2	p-S237-TBC1D1 [cytosol] (R-HSA-1454673) TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718)	0.745	6
Q92538	2	GBF1 [cytosol] (R-HSA-6807751) GBF1 [Golgi membrane] (R-HSA-199994)	0.731	4
Q9P0V3	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.731	5
Q9UQC2	1	GAB2 [cytosol] (R-HSA-508239)	0.727	7
P00519	5	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.725	4
P22893	1	Zfp36 [cytosol] (R-MMU-450562)	0.725	5
P36507	4	MAP2K2 [cytosol] (R-HSA-59504) MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) p-S,T-MAP2K2 [cytosol] (R-HSA-109848)	0.725	6
Q96B36	2	AKT1S1 [cytosol] (R-HSA-200155) p-S183,T246-AKT1S1 [cytosol] (R-HSA-200163)	0.725	4
Q99683	1	MAP3K5 [cytosol] (R-HSA-167709)	0.716	4
O75044	1	SRGAP2 [cytosol] (R-HSA-195131)	0.706	4
Q9UQB8	1	BAIAP2 [cytosol] (R-HSA-442574)	0.706	6
P30304	4	CDC25A [nucleoplasm] (R-HSA-143487) p-S124-CDC25A [cytosol] (R-HSA-69588) p-S124-CDC25A [nucleoplasm] (R-HSA-143488) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634)	0.701	10
Q9UQ35	1	SRRM2 [nucleoplasm] (R-HSA-8865888)	0.674	3
P21359	1	NF1(2-2839) [cytosol] (R-HSA-947770)	0.671	4
Q14671	1	PUM1 [cytosol] (R-HSA-434211)	0.671	5
Q13627	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.669	3
Q92574	1	TSC1 [plasma membrane] (R-HSA-165169)	0.669	3
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.667	3
P42858	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	11
Q12778	5	Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306)	0.643	3
Q70EL4	1	USP43 [nucleoplasm] (R-HSA-5653784)	0.643	3
Q8WX92	2	NELFB [cytosol] (R-HSA-9603526) NELFB [nucleoplasm] (R-HSA-112427)	0.643	3
Q9NQC7	3	CYLD [cytosol] (R-HSA-741420) K48polyUb-K338, K530-CYLD [cytosol] (R-HSA-9818664) p-S418-CYLD [cytosol] (R-HSA-5212667)	0.643	3
O43166	1	SPAR [cytosol] (R-HSA-6794278)	0.615	3
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	15
P25054	5	APC [cytosol] (R-HSA-2976015) APC [nucleoplasm] (R-HSA-3361755) APC(1-777) [cytosol] (R-HSA-2976014) APC(778-2843) [cytosol] (R-HSA-2976013) K63polyUb-APC [cytosol] (R-HSA-5246690)	0.615	3
P47974	1	ZFP36L2 [cytosol] (R-HSA-9819194)	0.615	4
Q08495	1	DMTN [cytosol] (R-HSA-5216222)	0.615	4
Q13009	1	TIAM1 [cytosol] (R-HSA-195013)	0.615	3
Q9NYA4	1	MTMR4 [early endosome membrane] (R-HSA-2187404)	0.615	4
Q9UQ84	1	EXO1 [nucleoplasm] (R-HSA-5357514)	0.615	3
Q15569	1	TESK1 [cytosol] (R-HSA-446396)	0.611	4
P55040	1	GEM [plasma membrane] (R-HSA-9769962)	0.597	4
P61587	1	RND3 [plasma membrane] (R-HSA-9696265)	0.59	3
Q9UDY2	3	TJP2 [cytosol] (R-HSA-2064412) TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897)	0.589	2
Q9UKV3	3	ACIN1 [cytosol] (R-HSA-212519) ACIN1(1-1093) [cytosol] (R-HSA-212520) ACIN1(1094-1341) [cytosol] (R-HSA-212516)	0.589	2
Q9NYF0	1	DACT1 [cytosol] (R-HSA-4641144)	0.581	4
P61588	1	RND3 [plasma membrane] (R-MMU-9696265)	0.576	5
P49757	1	NUMB [plasma membrane] (R-HSA-443595)	0.569	3
Q9Y2H2	1	INPP5F [early endosome membrane] (R-HSA-8849952)	0.569	4
O14744	2	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.564	2
O14757	2	CHEK1 [nucleoplasm] (R-HSA-113826) p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838)	0.564	2
Q14739	2	LBR [nuclear envelope] (R-HSA-194637) p-S71,S86-LBR [nuclear envelope] (R-HSA-9624811)	0.564	2
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	3
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.553	2
P08670	7	VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(2-429) [cytosol] (R-HSA-350317) VIM(2-85) [cytosol] (R-HSA-350264) VIM(260-466) [cytosol] (R-HSA-350314) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294)	0.548	3
A0MZ66	1	KIAA1598 [cytosol] (R-HSA-443599)	0.527	2
O60573	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.527	2
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.527	4
P19320	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
P42285	1	SKIV2L2 [nucleoplasm] (R-HSA-6791189)	0.527	2
P62993	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	3
Q14966	1	ZNF638 [nucleoplasm] (R-HSA-8939429)	0.527	2
Q6PJG9	1	SALM3 [plasma membrane] (R-HSA-197883)	0.527	2
Q9BST9	1	RTKN [cytosol] (R-HSA-5666184)	0.527	2
Q9BZ23	1	PANK2(111-570) [mitochondrial intermembrane space] (R-HSA-196803)	0.527	2
Q9C0I1	1	MTMR12 [cytosol] (R-HSA-6809657)	0.527	2
Q9HC77	2	CENPJ [cytosol] (R-HSA-380291) p-S589,S595-CENPJ [cytosol] (R-HSA-6801670)	0.527	2
Q9NRR6	1	INPP5E [cytosol] (R-HSA-1604585)	0.527	2
Q9P2Y5	1	UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.527	2
P55957	4	BID(1-195) [cytosol] (R-HSA-50825) BID(62-195) [cytosol] (R-HSA-139953) MYS-BID(62-195) [cytosol] (R-HSA-141373) MYS-BID(62-195) [mitochondrial outer membrane] (R-HSA-114266)	0.524	2
Q11184	1	let-756 [extracellular region] (R-CEL-189898)	0.508	2
O00429	2	DNM1L [cytosol] (R-HSA-351943) DNM1L [mitochondrial outer membrane] (R-HSA-351942)	0.483	4
O43303	1	CCP110 [cytosol] (R-HSA-380261)	0.483	2
P31947	1	SFN [cytosol] (R-HSA-1445105)	0.483	4
P56945	2	BCAR1 [cytosol] (R-HSA-201625) p-Y165,Y664-BCAR1 [cytosol] (R-HSA-8848723)	0.483	3
Q96ST8	1	CEP89 [cytosol] (R-HSA-5620930)	0.483	3
Q9NPI6	1	DCP1A [cytosol] (R-HSA-430043)	0.483	3
Q9Y580	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.483	2

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