Reactome | UniProt:P38398 BRCA1

UniProt:P38398 BRCA1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

BRCA1_HUMAN, E9PFZ0, O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9

List of interactors in Reactome

Interactors (38)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
Q9BX63	1	p-S990,Ac-K1249-BRIP1 [nucleoplasm] (R-HSA-5687710)	0.979	33
Q99728	1	BARD1 [nucleoplasm] (R-HSA-5659775)	0.955	19
Q99708	1	RBBP8 [nucleoplasm] (R-HSA-912399)	0.935	15
Q86YC2	2	PALB2 [cytosol] (R-HSA-9795739) PALB2 [nucleoplasm] (R-HSA-419548)	0.909	27
Q6UWZ7	1	p-S406-FAM175A [nucleoplasm] (R-HSA-5682575)	0.86	16
P03372	2	ESR1 [nucleoplasm] (R-HSA-446168) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302)	0.811	16
Q96RL1	1	UIMC1 [nucleoplasm] (R-HSA-5682574)	0.78	13
O15360	1	FANCA [nucleoplasm] (R-HSA-419541)	0.747	5
P51587	2	BRCA2 [cytosol] (R-HSA-9709265) BRCA2 [nucleoplasm] (R-HSA-50951)	0.727	8
Q06609	2	p-T309-RAD51 [nucleoplasm] (R-HSA-5685231) RAD51 [nucleoplasm] (R-HSA-62637)	0.718	6
Q14192	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.715	6
P16104	1	H2AFX [nucleoplasm] (R-HSA-56151)	0.714	4
Q12888	3	monoSUMO1-K-TP53BP1 [nucleoplasm] (R-HSA-2997591) p-S25,S1778-TP53BP1 [nucleoplasm] (R-HSA-5683418) TP53BP1 [nucleoplasm] (R-HSA-61175)	0.7	5
P27694	2	polySUMO2,3-K449,K577-RPA1 [nucleoplasm] (R-HSA-4551644) RPA1 [nucleoplasm] (R-HSA-68461)	0.65	3
P38398	3	BRCA1 [nucleoplasm] (R-HSA-50949) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624)	0.65	4
Q14676	3	MDC1 [nucleoplasm] (R-HSA-75231) monoSUMO1-K1840-MDC1 [nucleoplasm] (R-HSA-4570546) polySUMO2,3-K1840-MDC1 [nucleoplasm] (R-HSA-4570473)	0.629	4
P40692	1	MLH1 [nucleoplasm] (R-HSA-912495)	0.615	3
P46736	1	BRCC3 [nucleoplasm] (R-HSA-5682577)	0.615	3
P63165	2	SUMO1 [nucleoplasm] (R-HSA-877304) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831)	0.602	3
Q8WX92	2	NELFB [cytosol] (R-HSA-9603526) NELFB [nucleoplasm] (R-HSA-112427)	0.602	5
Q61188	1	Ezh2 [nucleoplasm] (R-MMU-5617899)	0.591	5
P61956	2	SUMO2 [nucleoplasm] (R-HSA-2984281) SUMO2(1-95) [nucleoplasm] (R-HSA-2990837)	0.589	2
Q9BXW9	1	FANCD2 [nucleoplasm] (R-HSA-419522)	0.583	3
Q16666	1	IFI16 [cytosol] (R-HSA-1834934)	0.556	9
P04637	2	polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 [nucleoplasm] (R-HSA-69488)	0.544	2
Q92560	1	BAP1 [nucleoplasm] (R-HSA-5689665)	0.543	3
P11388	3	monoSUMO1-K-TOP2A [nucleoplasm] (R-HSA-4641367) polySUMO2,3-TOP2A [nucleoplasm] (R-HSA-4641298) TOP2A [nucleoplasm] (R-HSA-1362276)	0.524	3
P62136	1	PPP1CA [cytosol] (R-HSA-163525)	0.524	2
Q13085	2	ACACA [cytosol] (R-HSA-1660609) Btn-ACACA [cytosol] (R-HSA-2976730)	0.524	2
P10809	1	HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.508	2
P52292	2	KPNA2 [cytosol] (R-HSA-205976) KPNA2 [nucleoplasm] (R-HSA-206045)	0.508	3
Q7Z569	1	BRAP [cytosol] (R-HSA-5672938)	0.508	3
O75330	1	HMMR [cytosol] (R-HSA-8861624)	0.499	4
Q9NWV8	1	BABAM1 [nucleoplasm] (R-HSA-5682582)	0.483	2
Q9NXR7	1	BRE [nucleoplasm] (R-HSA-5682579)	0.483	2
Q9ULW0	1	TPX2 [cytosol] (R-HSA-8853407)	0.483	4
O14757	2	CHEK1 [nucleoplasm] (R-HSA-113826) p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838)	0.463	3
P24385	4	CCND1 [cytosol] (R-HSA-68328) CCND1 [nucleoplasm] (R-HSA-113832) p-T286-CCND1 [cytosol] (R-HSA-75813) p-T286-CCND1 [nucleoplasm] (R-HSA-75811)	0.463	3

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