Reactome | UniProt:P63104 YWHAZ

UniProt:P63104 YWHAZ

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

1433Z_HUMAN, A8K1N0, B7Z465, P29213, P29312, Q32P43, Q5XJ08, Q6GPI2, Q6IN74, Q6NUR9, Q6P3U9, Q86V33

List of interactors in Reactome

Interactors (63)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.962	31
P30305	3	CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734) p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644)	0.924	10
P15056	3	BRAF [cytosol] (R-HSA-167224) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S446,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679)	0.91	11
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.907	11
P49815	3	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548)	0.903	10
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.864	9
Q92934	4	BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297) p-S99-BAD [cytosol] (R-HSA-198335)	0.851	8
Q02241	2	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695)	0.836	6
P56524	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.809	6
P46937	7	p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.803	9
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.772	6
P40818	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.77	4
P26045	2	PTPN3 [cytosol] (R-HSA-8867650) PTPN3 [plasma membrane] (R-HSA-5490317)	0.763	5
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.725	5
P10636	3	MAPT [cytosol] (R-HSA-201574) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642)	0.723	8
Q99683	1	MAP3K5 [cytosol] (R-HSA-167709)	0.716	4
Q6PKG0	1	LARP1 [cytosol] (R-HSA-9760421)	0.702	3
P06733	1	ENO1 [cytosol] (R-HSA-71437)	0.692	3
O43524	9	Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) FOXO3 [cytosol] (R-HSA-5687032) FOXO3 [nucleoplasm] (R-HSA-199305) p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289)	0.688	3
P04792	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.678	4
P57059	1	SIK1 [nucleoplasm] (R-HSA-5656504)	0.677	5
P31947	1	SFN [cytosol] (R-HSA-1445105)	0.669	3
Q9Y4H2	1	IRS2 [cytosol] (R-HSA-57528)	0.669	3
P23528	2	CFL1 [cytosol] (R-HSA-350751) p-S3-CFL1 [cytosol] (R-HSA-399813)	0.656	3
P61587	1	RND3 [plasma membrane] (R-HSA-9696265)	0.655	11
O14744	2	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.646	3
Q61337	6	Bad [cytosol] (R-MMU-3139043) Bad [cytosol] (R-MMU-50662) Bad [mitochondrial outer membrane] (R-MMU-114242) p-S136-Bad [cytosol] (R-MMU-3139049) phospho-Bad [cytosol] (R-MMU-217297) phospho-Bad [cytosol] (R-MMU-198335)	0.643	3
Q9UQC2	1	GAB2 [cytosol] (R-HSA-508239)	0.643	4
Q9Y3M2	1	CBY1 [nucleoplasm] (R-HSA-3769210)	0.643	3
Q01113	1	IL9R [plasma membrane] (R-HSA-449790)	0.635	5
P00519	4	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251)	0.623	3
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	14
Q15831	2	STK11 [cytosol] (R-HSA-380954) STK11 [nucleoplasm] (R-HSA-164119)	0.61	6
O00273	4	DFFA [cytosol] (R-HSA-211221) DFFA(1-117) [nucleoplasm] (R-HSA-211185) DFFA(118-224) [nucleoplasm] (R-HSA-211205) DFFA(225-331) [nucleoplasm] (R-HSA-211188)	0.589	2
Q9UDY2	3	TJP2 [cytosol] (R-HSA-2064412) TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897)	0.589	2
P16104	1	H2AFX [nucleoplasm] (R-HSA-56151)	0.577	6
P55072	2	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [cytosol] (R-HSA-1181251)	0.573	2
O14980	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.564	2
O75044	1	SRGAP2 [cytosol] (R-HSA-195131)	0.564	2
P02545	1	LMNA(1-646) [nuclear envelope] (R-HSA-535479)	0.564	2
P04637	2	polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 [nucleoplasm] (R-HSA-69488)	0.564	2
P06576	1	ATP5B [mitochondrial matrix] (R-HSA-164576)	0.564	2
P06748	6	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) NPM1 [cytosol] (R-HSA-3008211) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) p-S4-NPM1 [cytosol] (R-HSA-6801679) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056)	0.564	2
P07910	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.564	2
P08670	7	VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(2-429) [cytosol] (R-HSA-350317) VIM(2-85) [cytosol] (R-HSA-350264) VIM(260-466) [cytosol] (R-HSA-350314) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294)	0.564	2
P30307	8	CDC25C [cytosol] (R-HSA-157879) CDC25C [nucleoplasm] (R-HSA-69741) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-S198-CDC25C [cytosol] (R-HSA-8981697) p-S198-CDC25C [nucleoplasm] (R-HSA-156668) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654)	0.564	2
P31327	1	CPS1 [mitochondrial matrix] (R-HSA-70544)	0.564	2
P60709	2	ACTB(1-375) [cytosol] (R-HSA-201861) ACTB(1-375) [nucleoplasm] (R-HSA-3321990)	0.564	3
P62805	11	AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531)	0.564	3
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.564	3
P68104	4	EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [lysosomal membrane] (R-HSA-9626022) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.564	2
P30291	3	p-S53-WEE1 [nucleoplasm] (R-HSA-156694) p-WEE1 [nucleoplasm] (R-HSA-156491) WEE1 [nucleoplasm] (R-HSA-69253)	0.544	3
P30304	4	CDC25A [nucleoplasm] (R-HSA-143487) p-S124-CDC25A [cytosol] (R-HSA-69588) p-S124-CDC25A [nucleoplasm] (R-HSA-143488) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634)	0.544	2
P07359	1	GP1BA [plasma membrane] (R-HSA-55861)	0.527	2
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.527	2
P29074	1	PTPN4 [cytosol] (R-HSA-8877173)	0.527	2
P29353	2	p-Y427-SHC1 [cytosol] (R-HSA-74684) SHC1 [cytosol] (R-HSA-74680)	0.527	2
P62993	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	3
Q02750	4	MAP2K1 [cytosol] (R-HSA-59502) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.527	4
Q12778	5	Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306)	0.527	3
Q63767	2	Bcar1 [cytosol] (R-RNO-201625) phospho-Bcar1 [cytosol] (R-RNO-8848723)	0.527	2
Q9UQB8	1	BAIAP2 [cytosol] (R-HSA-442574)	0.527	3
Q6PJG9	1	SALM3 [plasma membrane] (R-HSA-197883)	0.462	3

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