Reactome | UniProt:Q04917 YWHAH

UniProt:Q04917 YWHAH

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

1433F_HUMAN

List of interactors in Reactome

Interactors (109)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.936	27
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.91	13
P46937	8	p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y407-YAP1 [cytosol] (R-HSA-9865208) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322)	0.894	11
P56524	3	HDAC4 [nucleoplasm] (R-HSA-351581) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029)	0.886	10
Q02241	2	KIF23 [nucleoplasm] (R-HSA-156709) p-S911,S912-KIF23 [nucleoplasm] (R-HSA-156695)	0.886	9
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.877	11
P30305	3	CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734) p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644)	0.869	8
P49815	3	p-S939,S1130,T1462-TSC2 [cytosol] (R-HSA-165164) p-S939,T1462-TSC2 [cytosol] (R-HSA-199484) TSC2 [cytosol] (R-HSA-2980548)	0.851	8
P15056	3	BRAF [cytosol] (R-HSA-167224) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S446,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679)	0.848	11
Q92934	4	BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297) p-S99-BAD [cytosol] (R-HSA-198335)	0.845	8
P30307	8	CDC25C [cytosol] (R-HSA-157879) CDC25C [nucleoplasm] (R-HSA-69741) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-S198-CDC25C [cytosol] (R-HSA-8981697) p-S198-CDC25C [nucleoplasm] (R-HSA-156668) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654)	0.837	7
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.837	7
Q02750	4	MAP2K1 [cytosol] (R-HSA-59502) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.837	8
Q96B36	2	AKT1S1 [cytosol] (R-HSA-200155) p-S183,T246-AKT1S1 [cytosol] (R-HSA-200163)	0.837	7
P00519	5	ABL1 [cytosol] (R-HSA-375987) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.827	6
O75044	1	SRGAP2 [cytosol] (R-HSA-195131)	0.802	6
P26045	2	PTPN3 [cytosol] (R-HSA-8867650) PTPN3 [plasma membrane] (R-HSA-5490317)	0.802	6
Q86TI0	2	p-S237-TBC1D1 [cytosol] (R-HSA-1454673) TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718)	0.802	7
Q9UQB8	1	BAIAP2 [cytosol] (R-HSA-442574)	0.802	9
Q9UQC2	1	GAB2 [cytosol] (R-HSA-508239)	0.802	7
Q9Y4H2	1	IRS2 [cytosol] (R-HSA-57528)	0.802	8
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.788	5
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.784	6
O43524	11	Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841849) FOXO3 [cytosol] (R-HSA-5687032) FOXO3 [nucleoplasm] (R-HSA-199305) FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841824) p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289)	0.774	6
Q13009	1	TIAM1 [cytosol] (R-HSA-195013)	0.774	5
P40818	2	p-T945-USP8 [cytosol] (R-HSA-1358714) USP8 [cytosol] (R-HSA-917720)	0.745	7
P47974	1	ZFP36L2 [cytosol] (R-HSA-9819194)	0.745	7
Q12778	5	Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306)	0.745	6
Q96PU5	2	NEDD4L [cytosol] (R-HSA-976003) NEDD4L [nucleoplasm] (R-HSA-2176420)	0.745	5
Q9P0V3	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.745	6
Q9NRR6	1	INPP5E [cytosol] (R-HSA-1604585)	0.744	4
Q99683	1	MAP3K5 [cytosol] (R-HSA-167709)	0.738	4
O60573	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.725	4
P36507	4	MAP2K2 [cytosol] (R-HSA-59504) MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) p-S,T-MAP2K2 [cytosol] (R-HSA-109848)	0.725	5
Q13627	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.725	5
Q70EL4	1	USP43 [nucleoplasm] (R-HSA-5653784)	0.725	4
Q92574	1	TSC1 [plasma membrane] (R-HSA-165169)	0.725	4
Q9UBF8	1	PI4KB [cytosol] (R-HSA-1604615)	0.725	5
Q96L34	1	MARK4 [cytosol] (R-HSA-5626653)	0.723	7
P41743	2	PRKCI [cytosol] (R-HSA-58206) PRKCI [nucleoplasm] (R-HSA-9021345)	0.708	4
Q15643	1	TRIP11 [Golgi membrane] (R-HSA-5617602)	0.706	5
Q9H0H5	1	RACGAP1 [cytosol] (R-HSA-195122)	0.706	4
Q9HC77	2	CENPJ [cytosol] (R-HSA-380291) p-S589,S595-CENPJ [cytosol] (R-HSA-6801670)	0.706	4
Q9UQ35	1	SRRM2 [nucleoplasm] (R-HSA-8865888)	0.706	4
Q9UQ84	1	EXO1 [nucleoplasm] (R-HSA-5357514)	0.706	5
Q9Y580	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.706	4
Q96ST8	1	CEP89 [cytosol] (R-HSA-5620930)	0.68	6
P21359	1	NF1(2-2839) [cytosol] (R-HSA-947770)	0.671	4
P30291	3	p-S53-WEE1 [nucleoplasm] (R-HSA-156694) p-WEE1 [nucleoplasm] (R-HSA-156491) WEE1 [nucleoplasm] (R-HSA-69253)	0.671	4
P30304	4	CDC25A [nucleoplasm] (R-HSA-143487) p-S124-CDC25A [cytosol] (R-HSA-69588) p-S124-CDC25A [nucleoplasm] (R-HSA-143488) p-S40,S116,S261-CDC25A [nucleoplasm] (R-HSA-8863634)	0.671	4
P35568	1	IRS1 [cytosol] (R-HSA-74769)	0.671	4
Q08495	1	DMTN [cytosol] (R-HSA-5216222)	0.671	6
Q6PKG0	1	LARP1 [cytosol] (R-HSA-9760421)	0.671	6
Q92597	1	NDRG1 [cytosol] (R-HSA-5628834)	0.671	4
Q9UDY2	3	TJP2 [cytosol] (R-HSA-2064412) TJP2 [plasma membrane] (R-HSA-351862) TJP2(?-?) [plasma membrane] (R-HSA-351897)	0.671	4
P37840	3	p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.646	4
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.643	6
P98177	4	Ac-K-FOXO4 [nucleoplasm] (R-HSA-9617761) FOXO4 [nucleoplasm] (R-HSA-5690183) p-T32,S197,S262-FOXO4 [cytosol] (R-HSA-9614415) SOH-C481-FOXO4 [nucleoplasm] (R-HSA-9617655)	0.643	3
Q13322	1	GRB10 [cytosol] (R-HSA-110009)	0.643	4
Q14155	1	ARHGEF7 [cytosol] (R-HSA-430346)	0.643	3
Q14457	1	BECN1 [cytosol] (R-HSA-1632841)	0.643	3
Q14966	1	ZNF638 [nucleoplasm] (R-HSA-8939429)	0.643	3
Q5SQI0	1	ATAT [cytosol] (R-HSA-5618184)	0.643	4
Q8IX03	1	WWC1 [cytosol] (R-HSA-2038400)	0.643	3
Q9BZ23	1	PANK2(111-570) [mitochondrial intermembrane space] (R-HSA-196803)	0.643	3
Q9GZV5	3	p-S89-WWTR1 [cytosol] (R-HSA-2028665) WWTR1 [cytosol] (R-HSA-1629773) WWTR1 [nucleoplasm] (R-HSA-1629775)	0.643	3
Q9H1K1	1	ISCU [cytosol] (R-HSA-9771680)	0.643	3
Q9P2Y5	1	UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.643	3
O43166	1	SPAR [cytosol] (R-HSA-6794278)	0.615	4
P31947	1	SFN [cytosol] (R-HSA-1445105)	0.615	6
P56945	2	BCAR1 [cytosol] (R-HSA-201625) p-Y165,Y664-BCAR1 [cytosol] (R-HSA-8848723)	0.615	4
Q14739	2	LBR [nuclear envelope] (R-HSA-194637) p-S71,S86-LBR [nuclear envelope] (R-HSA-9624811)	0.615	4
Q6N021	1	TET2 [nucleoplasm] (R-HSA-5221011)	0.615	3
Q9NPI6	1	DCP1A [cytosol] (R-HSA-430043)	0.615	4
Q9NYA4	1	MTMR4 [early endosome membrane] (R-HSA-2187404)	0.615	4
Q9Y2X7	2	GIT1 [cytosol] (R-HSA-430326) p-Y383-GIT1 [cytosol] (R-HSA-3928463)	0.615	4
P49674	1	CSNK1E [cytosol] (R-HSA-205877)	0.604	3
O60565	1	GREM1 [extracellular region] (R-HSA-9831023)	0.593	5
O00443	1	PIK3C2A [cytosol] (R-HSA-1604624)	0.569	4
Q92538	2	GBF1 [cytosol] (R-HSA-6807751) GBF1 [Golgi membrane] (R-HSA-199994)	0.569	4
Q9NQC7	3	CYLD [cytosol] (R-HSA-741420) K48polyUb-K338, K530-CYLD [cytosol] (R-HSA-9818664) p-S418-CYLD [cytosol] (R-HSA-5212667)	0.569	3
O15530	3	p-S241-PDPK1 [cytosol] (R-HSA-9860799) PDPK1 [cytosol] (R-HSA-202210) PDPK1 [plasma membrane] (R-HSA-61459)	0.564	3
O14757	2	CHEK1 [nucleoplasm] (R-HSA-113826) p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838)	0.527	2
O15294	2	OGT [cytosol] (R-HSA-9687814) OGT [nucleoplasm] (R-HSA-3321845)	0.527	2
O43318	2	MAP3K7 [cytosol] (R-HSA-168156) p-T187-MAP3K7 [cytosol] (R-HSA-206014)	0.527	2
O75030	2	MITF [nucleoplasm] (R-HSA-201592) monoSUMO1-K289,423-MITF [nucleoplasm] (R-HSA-3232153)	0.527	2
P29074	1	PTPN4 [cytosol] (R-HSA-8877173)	0.527	2
Q07955	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.527	2
Q13356	2	PPIL2 [Golgi lumen] (R-HSA-204475) PPIL2 [nucleoplasm] (R-HSA-9769562)	0.527	2
Q13496	1	MTM1 [cytosol] (R-HSA-1604646)	0.527	2
Q15052	1	ARHGEF6 [cytosol] (R-HSA-195017)	0.527	2
Q2M1P5	1	KIF7 [ciliary tip] (R-HSA-5610395)	0.527	2
Q3MII6	1	TBC1D25 [autophagosome] (R-HSA-8854607)	0.527	2
Q6PJF5	2	iRHOM2 [endoplasmic reticulum membrane] (R-HSA-9662859) iRHOM2 [Golgi lumen] (R-HSA-9673787)	0.527	2
Q6VY07	1	PACS1 [cytosol] (R-HSA-167634)	0.527	2
Q7Z3C6	1	ATG9A [phagophore assembly site membrane] (R-HSA-5671732)	0.527	2
Q8IUC4	1	RHPN2 [cytosol] (R-HSA-5667007)	0.527	2
Q96CV9	3	OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595)	0.527	2
Q9BZF9	1	UACA [cytosol] (R-HSA-6804636)	0.527	2
Q9HCG8	1	CWC22 [nucleoplasm] (R-HSA-8865956)	0.527	2
Q9JIR4	1	RIMS1 [cytosol] (R-RNO-210407)	0.527	3
Q9NXD2	1	MTMR10 [cytosol] (R-HSA-6810028)	0.527	2
Q9P0N9	1	TBC1D7 [cytosol] (R-HSA-8854154)	0.527	2
Q9Y3M2	1	CBY1 [nucleoplasm] (R-HSA-3769210)	0.527	2
P48552	2	monoSUMO1-K756,K1154-NRIP1 [nucleoplasm] (R-HSA-4086057) NRIP1 [nucleoplasm] (R-HSA-4086031)	0.489	2
P10636	3	MAPT [cytosol] (R-HSA-201574) MAPT(2-421) [cytosol] (R-HSA-350628) MAPT(422-758) [cytosol] (R-HSA-350642)	0.483	2
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	11
P48729	2	CSNK1A1 [cilium] (R-HSA-5632507) CSNK1A1 [cytosol] (R-HSA-195263)	0.483	2
Q6PJG9	1	SALM3 [plasma membrane] (R-HSA-197883)	0.462	3

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