Reactome | UniProt:Q12933 TRAF2

UniProt:Q12933 TRAF2

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

TRAF2_HUMAN, A8K107, B4DPJ7, Q7Z337, Q96NT2

List of interactors in Reactome

Interactors (93)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
Q13490	3	BIRC2 [cytosol] (R-HSA-50847) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931)	0.951	19
Q15628	1	TRADD [cytosol] (R-HSA-66376)	0.942	14
Q12933	1	TRAF2 [cytosol] (R-HSA-66370)	0.936	12
Q9Y4K3	1	TRAF6 [cytosol] (R-HSA-166366)	0.905	10
Q9UHD2	2	p-TBK1 [cytosol] (R-HSA-9008705) TBK1 [cytosol] (R-HSA-166267)	0.893	9
Q13077	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.887	14
Q13546	4	K48polyUb-K571,K604,K627-RIPK1 [cytosol] (R-HSA-9796639) RIPK1 [cytosol] (R-HSA-168651) RIPK1 [plasma membrane] (R-HSA-937073) RIPK1(1-324) [cytosol] (R-HSA-5212664)	0.884	10
Q92844	1	TANK [cytosol] (R-HSA-933407)	0.854	10
O95999	3	BCL10 [cytosol] (R-HSA-202447) K48polyUb-BCL10 [cytosol] (R-HSA-8939329) p-BCL10 [cytosol] (R-HSA-202488)	0.85	11
P21580	1	TNFAIP3 [cytosol] (R-HSA-688989)	0.831	10
Q6FIF0	1	ZFAND6 [cytosol] (R-HSA-9033138)	0.809	8
P46527	5	CDKN1B [cytosol] (R-HSA-198622) CDKN1B [nucleoplasm] (R-HSA-182563) p-S10 CDKN1B [cytosol] (R-HSA-9632829) p-S10 CDKN1B [nucleoplasm] (R-HSA-9632832) p-Y88-CDKN1B [cytosol] (R-HSA-8848438)	0.799	6
P01375	3	TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(77-233) [extracellular region] (R-HSA-976821)	0.788	9
O75604	1	USP2 [nucleoplasm] (R-HSA-5689946)	0.781	7
Q13526	2	PIN1 [cytosol] (R-HSA-9626823) PIN1 [nucleoplasm] (R-HSA-936016)	0.781	7
Q92917	1	GPKOW [nucleoplasm] (R-HSA-8850839)	0.781	7
Q9NRN7	1	AASDHPPT [cytosol] (R-HSA-199235)	0.781	7
Q99558	5	Active NIK [cytosol] (R-HSA-5607646) K48polyUb-NIK [cytosol] (R-HSA-5668525) MAP3K14 [cytosol] (R-HSA-168189) p-MAP3K14 [cytosol] (R-HSA-168187) p-T559-MAP3K14 [cytosol] (R-HSA-5668531)	0.749	9
Q7Z434	1	MAVS [mitochondrial outer membrane] (R-HSA-913730)	0.742	5
O60437	1	PPL [cytosol] (R-HSA-6810850)	0.718	6
P07947	1	YES1 [cytosol] (R-HSA-373640)	0.718	6
Q96NC0	1	ZMAT2 [nucleoplasm] (R-HSA-9770248)	0.718	6
Q99683	1	MAP3K5 [cytosol] (R-HSA-167709)	0.704	4
Q92956	1	TNFRSF14 [plasma membrane] (R-HSA-198101)	0.692	3
O43353	1	RIPK2 [cytosol] (R-HSA-168402)	0.688	3
P20333	1	TNFRSF1B [plasma membrane] (R-HSA-5661484)	0.678	4
P36941	1	LTBR [plasma membrane] (R-HSA-5668750)	0.669	4
Q14164	3	IKBKE [cytosol] (R-HSA-450225) monoSUMO1-K231-p-S172-IKBKE [nucleoplasm] (R-HSA-4755535) p-S172-IKBKE [nucleoplasm] (R-HSA-4755521)	0.669	3
Q8N9N5	1	BANP [nucleoplasm] (R-HSA-3221973)	0.666	4
Q96EK7	1	FAM120B [nucleoplasm] (R-HSA-8940294)	0.666	4
Q9UKG1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.653	3
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.635	4
O75460	1	ERN1 [endoplasmic reticulum membrane] (R-HSA-381076)	0.628	3
O43464	1	HTRA2 [mitochondrial intermembrane space] (R-HSA-56655)	0.615	3
P20334	1	Tnfrsf9 [plasma membrane] (R-MMU-5666996)	0.609	2
P28908	1	TNFRSF8 [plasma membrane] (R-HSA-5668758)	0.59	2
Q9Y6Q6	1	TNFRSF11A [plasma membrane] (R-HSA-5668756)	0.589	2
P09022	1	Hoxa1 [nucleoplasm] (R-MMU-5617924)	0.57	3
O00233	1	PSMD9 [cytosol] (R-HSA-68810)	0.556	3
O15169	1	AXIN1 [cytosol] (R-HSA-195249)	0.556	3
O75928	1	PIAS2-2 [nucleoplasm] (R-HSA-2993779)	0.556	3
O95363	1	FARS2(1-?) [mitochondrial matrix] (R-HSA-379565)	0.556	3
O95863	1	SNAI1 [nucleoplasm] (R-HSA-2980903)	0.556	3
O95995	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
P10599	4	2xHC-TXN [cytosol] (R-HSA-73668) 2xHC-TXN [nucleoplasm] (R-HSA-9617733) TXN [cytosol] (R-HSA-66000) TXN [nucleoplasm] (R-HSA-9617732)	0.556	3
P20618	2	pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143)	0.556	5
P22415	1	USF1 [nucleoplasm] (R-HSA-9023562)	0.556	3
P35227	1	PCGF2 [nucleoplasm] (R-HSA-389115)	0.556	3
P41182	1	BCL6 [nucleoplasm] (R-HSA-5223066)	0.556	3
P42858	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
P47897	1	QARS [mitochondrial matrix] (R-HSA-379592)	0.556	3
P49639	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
P55040	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
P55081	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
P63165	2	SUMO1 [nucleoplasm] (R-HSA-877304) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831)	0.556	3
Q08117	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
Q08426	1	EHHADH [peroxisomal matrix] (R-HSA-400155)	0.556	3
Q08495	1	DMTN [cytosol] (R-HSA-5216222)	0.556	3
Q13895	1	BYSL [cytosol] (R-HSA-6791518)	0.556	3
Q15052	1	ARHGEF6 [cytosol] (R-HSA-195017)	0.556	3
Q15742	1	NAB2 [nucleoplasm] (R-HSA-9612177)	0.556	3
Q16512	1	p-T774-PKN1 [cytosol] (R-HSA-5623651)	0.556	3
Q16656	1	NRF1 [nucleoplasm] (R-HSA-1592205)	0.556	3
Q2TBE0	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.556	3
Q49AN0	1	CRY2 [cytosol] (R-HSA-400255)	0.556	3
Q5T8I9	1	HENMT1 [cytosol] (R-HSA-5601916)	0.556	3
Q8IYH5	1	ZZZ3 [nucleoplasm] (R-HSA-3662283)	0.556	3
Q8N3R9	2	MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9689606) MPP5 [plasma membrane] (R-HSA-419969)	0.556	3
Q8WWZ3	1	EDARADD [cytosol] (R-HSA-5675659)	0.556	5
Q96BZ8	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
Q96JC9	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.556	3
Q99633	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
Q9GZQ4	1	NMUR2 [plasma membrane] (R-HSA-964816)	0.556	3
Q9H875	1	PRKRIP1 [nucleoplasm] (R-HSA-9769594)	0.556	3
Q9HAK2	1	EBF2 [nucleoplasm] (R-HSA-381317)	0.556	3
Q9NTX7	1	RNF146 [cytosol] (R-HSA-3640827)	0.556	3
Q9UHB7	1	AFF4 [nucleoplasm] (R-HSA-8932788)	0.556	3
O14641	1	DVL2 [cytosol] (R-HSA-201694)	0.553	2
Q7Z3B3	1	KANSL1 [nucleoplasm] (R-HSA-3321875)	0.553	2
Q9UM82	1	SPATA2 [cytosol] (R-HSA-9796351)	0.553	2
P26842	1	CD27 [plasma membrane] (R-HSA-5666994)	0.547	3
Q13627	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.547	3
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.536	2
Q13233	2	MAP3K1 [cytosol] (R-HSA-166866) p-T1400,T1412-MAP3K1 [cytosol] (R-HSA-2685607)	0.536	2
P49841	2	GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.527	2
Q14790	4	CASP8(1-479) [cytosol] (R-HSA-57031) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(385-479) [cytosol] (R-HSA-76158)	0.527	3
Q62925	2	MAP3K1 [cytosol] (R-RNO-166866) phospho-p-T1400,T1412-MAP3K1 [cytosol] (R-RNO-2685607)	0.527	2
Q9NR28	2	DIABLO [cytosol] (R-HSA-114298) DIABLO [mitochondrial intermembrane space] (R-HSA-64637)	0.527	3
P07174	7	Ngfr [cytosol] (R-RNO-194458) Ngfr [endosome] (R-RNO-209541) Ngfr [extracellular region] (R-RNO-194470) Ngfr [nucleoplasm] (R-RNO-197473) Ngfr [plasma membrane] (R-RNO-194509) Ngfr [plasma membrane] (R-RNO-194476) Ngfr [plasma membrane] (R-RNO-193664)	0.524	3
Q9NP84	1	TNFRSF12A [plasma membrane] (R-HSA-5675666)	0.499	3
O14920	3	IKBKB [cytosol] (R-HSA-168114) IKBKB Q432Pfs*62 [cytosol] (R-HSA-9628518) p-S177,S181-IKBKB [cytosol] (R-HSA-202506)	0.483	2
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	4
Q03135	3	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [plasma membrane] (R-HSA-534994)	0.463	3