Reactome | UniProt:Q14790 CASP8

UniProt:Q14790 CASP8

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

CASP8_HUMAN, O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81

List of interactors in Reactome

Interactors (22)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
Q13158	1	FADD [cytosol] (R-HSA-54639)	0.979	46
Q13546	4	K48polyUb-K571,K604,K627-RIPK1 [cytosol] (R-HSA-9796639) RIPK1 [cytosol] (R-HSA-168651) RIPK1 [plasma membrane] (R-HSA-937073) RIPK1(1-324) [cytosol] (R-HSA-5212664)	0.959	30
P50591	1	TNFSF10 [extracellular region] (R-HSA-66186)	0.919	20
P25445	1	FAS [plasma membrane] (R-HSA-66248)	0.911	15
P48023	1	FASLG(1-281) [extracellular region] (R-HSA-66212)	0.744	5
Q92851	3	CASP10(1-521) [cytosol] (R-HSA-933453) CASP10(220-415) [cytosol] (R-HSA-933458) CASP10(416-521) [cytosol] (R-HSA-933455)	0.734	6
Q15628	1	TRADD [cytosol] (R-HSA-66376)	0.725	6
Q14790	4	CASP8(1-479) [cytosol] (R-HSA-57031) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(385-479) [cytosol] (R-HSA-76158)	0.704	4
Q9UKL3	2	CASP8AP2 [nucleoplasm] (R-HSA-3927945) monoSUMO1-K1813-CASP8AP2 [nucleoplasm] (R-HSA-3927850)	0.704	5
O15519	1	CFLAR(1-376) [cytosol] (R-HSA-51925)	0.669	9
P51572	5	BCAP31 [endoplasmic reticulum membrane] (R-HSA-9714333) BCAP31(165-237) [endoplasmic reticulum membrane] (R-HSA-351909) BCAP31(2-164) [endoplasmic reticulum membrane] (R-HSA-351826) BCAP31(2-245) [endoplasmic reticulum membrane] (R-HSA-201587) BCAP31(238-246) [cytosol] (R-HSA-351912)	0.589	3
O15519	5	CFLAR(1-376) [cytosol] (R-HSA-3465408) CFLAR(1-480) [cytosol] (R-HSA-3371356) CFLAR(377-480) [cytosol] (R-HSA-3465483) K63polyUb-CFLAR(1-480) [cytosol] (R-HSA-9818805) M1polyUb-K351,K353-CFLAR(1-480) [cytosol] (R-HSA-9794015)	0.564	2
Q9Y572	5	K33polyUb-K197,302,364-RIPK3 [cytosol] (R-HSA-9794180) OGlcNAc-T467-RIPK3 [cytosol] (R-HSA-9687819) RIPK3 [cytosol] (R-HSA-450328) RIPK3(1-328) [cytosol] (R-HSA-9686917) RIPK3(329-518) [cytosol] (R-HSA-9686937)	0.564	2
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.556	3
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	3
P53350	4	p-T210-PLK1 [cytosol] (R-HSA-3000318) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [cytosol] (R-HSA-164603) PLK1 [nucleoplasm] (R-HSA-156720)	0.556	3
Q9BY76	3	ANGPTL4 [extracellular region] (R-HSA-381271) ANGPTL4 [extracellular region] (R-HSA-6784897) ANGPTL4(164-406) [extracellular region] (R-HSA-9762251)	0.547	2
Q12933	1	TRAF2 [cytosol] (R-HSA-66370)	0.527	3
Q13490	3	BIRC2 [cytosol] (R-HSA-50847) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931)	0.527	2
P29350	1	PTPN6 [cytosol] (R-HSA-197938)	0.524	3
P21580	1	TNFAIP3 [cytosol] (R-HSA-688989)	0.499	3
Q9UDY8	1	MALT1 [cytosol] (R-HSA-202461)	0.499	10