Robert M Stephens

 ORCID
https://orcid.org/0000-0001-5330-7610
Reviewed Pathways (7/7)
Date Identifier Pathway Reference
2016-08-05 R-HSA-6802957 Oncogenic MAPK signaling BibTex
2016-08-05 R-HSA-6802952 Signaling by BRAF and RAF fusions BibTex
2016-08-05 R-HSA-6802953 RAS signaling downstream of NF1 loss-of-function variants BibTex
2016-08-05 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF BibTex
2016-08-05 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802949 Signaling by RAS mutants BibTex
Reviewed Reactions (15/34)
Date Identifier Reaction Reference
2016-08-05 R-HSA-6802932 Dissociation of BRAF/RAF fusion complex BibTex
2016-08-05 R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers BibTex
2016-08-05 R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802927 BRAF and RAF fusion mutant dimers are phosphorylated BibTex
2016-08-05 R-HSA-6802837 Loss-of-function NF1 variants don't stimulate RAS GTPase activity BibTex
2016-08-05 R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF BibTex
2016-08-05 R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes BibTex
2016-08-05 R-HSA-8936731 Inactive BRAF mutants:mutant RAS:GTP bind RAF1 BibTex
2016-08-05 R-HSA-6802937 Inactive BRAF mutants bind mutant RAS:GTP BibTex
2016-08-05 R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants BibTex
2016-08-05 R-HSA-8936676 Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize BibTex
2016-08-05 R-HSA-6803230 Dissociation of moderate activity BRAF complexes BibTex