Robert M Stephens

 ORCID
https://orcid.org/0000-0001-5330-7610
Reviewed Pathways (10/10)
Date Identifier Pathway Reference
2016-08-05 R-HSA-6802957 Oncogenic MAPK signaling BibTex
2016-08-05 R-HSA-6802952 Signaling by BRAF and RAF1 fusions BibTex
2016-08-05 R-HSA-6802953 RAS signaling downstream of NF1 loss-of-function variants BibTex
2016-08-05 R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF BibTex
2016-08-05 R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802948 Signaling by high-kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802949 Signaling by RAS mutants BibTex
2016-08-05 R-HSA-9649948 Signaling downstream of RAS mutants BibTex
2016-08-05 R-HSA-9649913 RAS GTPase cycle mutants BibTex
2016-08-05 R-HSA-9753510 Signaling by RAS GAP mutants BibTex
Reviewed Reactions (34/34)
Date Identifier Reaction Reference
2016-08-05 R-HSA-6802932 Dissociation of BRAF/RAF fusion complex BibTex
2016-08-05 R-HSA-6802935 MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers BibTex
2016-08-05 R-HSA-6802933 p-BRAF and RAF fusion dimers phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802934 p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802927 BRAF and RAF fusion mutant dimers are phosphorylated BibTex
2016-08-05 R-HSA-6802837 Loss-of-function NF1 variants don't stimulate RAS GTPase activity BibTex
2016-08-05 R-HSA-6802943 RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802942 RAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802941 RAF is paradoxically phosphorylated downstream of kinase-inactive RAF BibTex
2016-08-05 R-HSA-6803234 Dissociation of paradoxically activated RAS:BRAF complexes BibTex
2016-08-05 R-HSA-8936731 Inactive BRAF mutants:mutant RAS:GTP bind RAF1 BibTex
2016-08-05 R-HSA-6802937 Inactive BRAF mutants bind mutant RAS:GTP BibTex
2016-08-05 R-HSA-6802918 Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants BibTex
2016-08-05 R-HSA-8936676 Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize BibTex
2016-08-05 R-HSA-6803230 Dissociation of moderate activity BRAF complexes BibTex
2016-08-05 R-HSA-6802921 Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802919 RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802914 RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802916 RAF is phosphorylated downstream of moderate kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802915 Moderate kinase activity BRAF mutants bind RAS:GTP BibTex
2016-08-05 R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants BibTex
2016-08-05 R-HSA-6803227 Dissociation of high activity BRAF complexes BibTex
2016-08-05 R-HSA-6802910 Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants BibTex
2016-08-05 R-HSA-6802911 High kinase activity BRAF complexes phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802912 High kinase activity BRAF mutants bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802930 Dimerization of BRAF V600E splice variants contributes to BRAF inhibitor resistance BibTex
2016-08-05 R-HSA-6803240 Homo- or heterodimerization of RAF downstream of mutant RAS BibTex
2016-08-05 R-HSA-6803233 Dissociation of oncogenic RAS:RAF complex BibTex
2016-08-05 R-HSA-6802922 Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS BibTex
2016-08-05 R-HSA-6802926 Mutant RAS:p-RAF complexes phosphorylate MAP2Ks BibTex
2016-08-05 R-HSA-6802925 Mutant RAS:p-RAF complexes bind MAP2Ks and MAPKs BibTex
2016-08-05 R-HSA-6802924 RAF is phosphorylated downstream of oncogenic RAS BibTex
2016-08-05 R-HSA-6802908 RAS mutants bind inactive RAF BibTex
2016-08-05 R-HSA-9651280 RAS GAP mutants aren't stimulated by GAPs BibTex
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