Karen Rothfels

Orcid ID
Ontario Institute for Cancer Research
Authored Pathways (15/127)
Date Identifier Pathway Reference
2017-09-29 R-HSA-8939211 ESR-mediated signaling BibTex
2017-09-29 R-HSA-9018519 Estrogen-dependent gene expression BibTex
2017-05-24 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases BibTex
2017-05-24 R-HSA-9006931 Signaling by Nuclear Receptors BibTex
2017-05-24 R-HSA-9006936 Signaling by TGF-beta family members BibTex
2017-05-24 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases BibTex
2017-05-24 R-HSA-9006925 Intracellular signaling by second messengers BibTex
2017-05-24 R-HSA-9006921 Integrin signaling BibTex
2017-02-07 R-HSA-8951664 Neddylation BibTex
2016-06-29 R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs BibTex
2016-06-29 R-HSA-9007101 Rab regulation of trafficking BibTex
2016-06-03 R-HSA-8873719 RAB geranylgeranylation BibTex
2016-05-11 R-HSA-8856828 Clathrin-mediated endocytosis BibTex
2016-05-11 R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis BibTex
2016-01-09 R-HSA-8853333 Signaling by FGFR2 fusions BibTex
Authored Reactions (15/859)
Date Identifier Reaction Reference
2018-02-23 R-HSA-9032751 Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 BibTex
2018-02-23 R-HSA-9038052 GREB1 binds ESR1:ESTG and co-activators BibTex
2018-02-23 R-HSA-9038163 ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators BibTex
2018-02-23 R-HSA-9038161 Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG BibTex
2018-02-23 R-HSA-9038029 27-hydroxysterol binds ESR1, ESR2 BibTex
2017-11-03 R-HSA-9029434 p-S363,S380,T573 RS6K translocates to the nucleus BibTex
2017-09-29 R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene BibTex
2017-09-29 R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene BibTex
2017-09-29 R-HSA-9023859 Estrogen-responsive TFF1 gene expression BibTex
2017-09-29 R-HSA-9012208 miR-26A and B bind to the 3'UTR of the KPNA2 mRNA BibTex
2017-09-29 R-HSA-9012209 Estrogen-responsive KPNA2 gene transcription BibTex
2017-09-29 R-HSA-9011966 Estrogen-responsive KDM4B gene expression BibTex
2017-09-29 R-HSA-9011961 GREB1 translation is negatively regulated by miR-26A and B BibTex
2017-09-29 R-HSA-9023846 Estrogen-responsive CTSD expression BibTex
2017-09-29 R-HSA-9012196 KPNA2 translation is negatively regulated by miR-26A and B BibTex
Reviewed Pathways (1/1)
Date Identifier Pathway Reference
2016-09-17 R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) BibTex
Reviewed Reactions (12/12)
Date Identifier Reaction Reference
2016-09-17 R-HSA-5618093 ATP hydrolysis by HSP90 BibTex
2016-09-17 R-HSA-5618080 HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus BibTex
2016-09-17 R-HSA-5618099 SH binds SHR within the HSP90 chaperone complex BibTex
2016-09-17 R-HSA-5618110 p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein BibTex
2016-09-17 R-HSA-5618073 FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein BibTex
2016-09-17 R-HSA-5618098 p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein BibTex
2016-09-17 R-HSA-5618105 FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein BibTex
2016-09-17 R-HSA-5618085 FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein BibTex
2016-09-17 R-HSA-5618107 ATP binding to HSP90 triggers conformation change BibTex
2016-09-17 R-HSA-3371503 STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein BibTex
2016-09-17 R-HSA-3371422 ATP hydrolysis by HSP70 BibTex
2016-09-17 R-HSA-3371590 HSP70 binds to HSP40:nascent protein BibTex