Peter D'Eustachio

 ORCID
https://orcid.org/0000-0002-5494-626X
Project
Reactome
Affiliation
NYU School of Medicine, Department of Biochemistry
Authored Pathways (156/156)
Date Identifier Pathway Reference
2021-12-13 R-HSA-9759774 Diseases of mitochondrial beta oxidation BibTex
2021-07-09 R-HSA-9735804 Diseases of nucleotide metabolism BibTex
2021-07-02 R-HSA-9735786 Nucleotide catabolism defects BibTex
2021-07-02 R-HSA-9735763 Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine BibTex
2021-07-02 R-HSA-9734207 Nucleotide salvage defects BibTex
2021-07-02 R-HSA-9734281 Defective HPRT1 disrupts guanine and hypoxanthine salvage BibTex
2021-07-02 R-HSA-9734735 Defective ADA disrupts (deoxy)adenosine deamination BibTex
2021-07-02 R-HSA-9734195 Defective APRT disrupts adenine salvage BibTex
2020-07-22 R-HSA-9694516 SARS-CoV-2 Infection BibTex
2020-01-06 R-HSA-9673163 Oleoyl-phe metabolism BibTex
2018-11-24 R-HSA-9629569 Protein hydroxylation BibTex
2017-01-13 R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin BibTex
2016-12-30 R-HSA-8953897 Cellular responses to stimuli BibTex
2016-12-29 R-HSA-8953854 Metabolism of RNA BibTex
2015-12-10 R-HSA-8848584 Wax and plasmalogen biosynthesis BibTex
2015-11-28 R-HSA-6814848 Glycerophospholipid catabolism BibTex
2015-11-02 R-HSA-6807062 Cholesterol biosynthesis via lathosterol BibTex
2015-11-02 R-HSA-6807047 Cholesterol biosynthesis via desmosterol BibTex
2015-11-02 R-HSA-6806667 Metabolism of fat-soluble vitamins BibTex
2015-11-02 R-HSA-6806664 Metabolism of vitamin K BibTex
2015-08-18 R-HSA-6791055 TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P BibTex
2015-08-18 R-HSA-6791462 TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P BibTex
2015-08-14 R-HSA-5661270 Formation of xylulose-5-phosphate BibTex
2015-02-26 R-HSA-5662853 Essential pentosuria BibTex
2015-02-24 R-HSA-6791465 Pentose phosphate pathway disease BibTex
2015-02-24 R-HSA-5659996 RPIA deficiency: failed conversion of R5P to RU5P BibTex
2015-02-24 R-HSA-6791461 RPIA deficiency: failed conversion of RU5P to R5P BibTex
2015-02-15 R-HSA-5659898 Intestinal saccharidase deficiencies BibTex
2015-01-29 R-HSA-5657560 Hereditary fructose intolerance BibTex
2015-01-29 R-HSA-5657562 Essential fructosuria BibTex
2015-01-13 R-HSA-162906 HIV Infection BibTex
2015-01-13 R-HSA-162587 HIV Life Cycle BibTex
2014-11-29 R-HSA-5652227 Fructose biosynthesis BibTex
2014-11-27 R-HSA-5652084 Fructose metabolism BibTex
2014-03-29 R-HSA-5358493 Synthesis of diphthamide-EEF2 BibTex
2014-03-25 R-HSA-5357609 Glycogen storage disease type II (GAA) BibTex
2014-03-05 R-HSA-5336415 Uptake and function of diphtheria toxin BibTex
2014-02-11 R-HSA-5250982 Toxicity of tetanus toxin (tetX) BibTex
2013-12-13 R-HSA-5210891 Uptake and function of anthrax toxins BibTex
2013-07-19 R-HSA-3229121 Glycogen storage diseases BibTex
2013-07-19 R-HSA-3814836 Glycogen storage disease type XV (GYG1) BibTex
2013-07-19 R-HSA-3858516 Glycogen storage disease type 0 (liver GYS2) BibTex
2013-07-19 R-HSA-3785653 Myoclonic epilepsy of Lafora BibTex
2013-07-19 R-HSA-3229133 Glycogen storage disease type Ib (SLC37A4) BibTex
2013-07-19 R-HSA-3282872 Severe congenital neutropenia type 4 (G6PC3) BibTex
2013-07-19 R-HSA-3878781 Glycogen storage disease type IV (GBE1) BibTex
2013-07-19 R-HSA-3828062 Glycogen storage disease type 0 (muscle GYS1) BibTex
2013-07-19 R-HSA-3274531 Glycogen storage disease type Ia (G6PC) BibTex
2012-07-06 R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins BibTex
2012-03-14 R-HSA-2161522 Abacavir ADME BibTex
2012-03-14 R-HSA-2161517 Abacavir transmembrane transport BibTex
2012-03-14 R-HSA-2161541 Abacavir metabolism BibTex
2012-03-05 R-HSA-2160456 Phenylketonuria BibTex
2012-02-03 R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression BibTex
2012-02-03 R-HSA-2028269 Signaling by Hippo BibTex
2010-06-26 R-HSA-2978092 Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate BibTex
2010-06-26 R-HSA-880009 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate BibTex
2010-02-06 R-HSA-500753 Pyrimidine biosynthesis BibTex
2010-02-06 R-HSA-499943 Interconversion of nucleotide di- and triphosphates BibTex
2009-08-22 R-GGA-433584 Sphingolipid metabolism BibTex
2009-08-21 R-HSA-428157 Sphingolipid metabolism BibTex
2009-08-21 R-HSA-1660661 Sphingolipid de novo biosynthesis BibTex
2009-05-23 R-GGA-421984 Heme synthesis BibTex
2009-05-16 R-GGA-421223 De novo synthesis of GMP BibTex
2009-05-15 R-GGA-421178 Urate synthesis BibTex
2009-05-15 R-GGA-421203 De novo synthesis of AMP BibTex
2009-05-01 R-GGA-419470 Nucleotide metabolism BibTex
2009-05-01 R-GGA-419469 Pyrimidine metabolism: de novo synthesis of UMP BibTex
2009-05-01 R-GGA-419474 Purine metabolism BibTex
2009-04-29 R-GGA-419140 De novo synthesis of IMP BibTex
2009-03-16 R-HSA-389887 Beta-oxidation of pristanoyl-CoA BibTex
2009-03-16 R-HSA-390247 Beta-oxidation of very long chain fatty acids BibTex
2009-02-11 R-HSA-75896 Plasmalogen biosynthesis BibTex
2009-02-11 R-HSA-390918 Peroxisomal lipid metabolism BibTex
2009-01-12 R-HSA-389661 Glyoxylate metabolism and glycine degradation BibTex
2009-01-11 R-HSA-389599 Alpha-oxidation of phytanate BibTex
2009-01-08 R-HSA-8978934 Metabolism of cofactors BibTex
2009-01-08 R-HSA-389542 NADPH regeneration BibTex
2008-12-03 R-HSA-74160 Gene expression (Transcription) BibTex
2008-11-29 R-HSA-379724 tRNA Aminoacylation BibTex
2008-11-29 R-HSA-379726 Mitochondrial tRNA aminoacylation BibTex
2008-11-29 R-HSA-379716 Cytosolic tRNA aminoacylation BibTex
2008-09-10 R-GGA-372442 Lipid metabolism BibTex
2008-09-10 R-GGA-353098 Carbohydrate metabolism BibTex
2008-09-10 R-GGA-352875 Gluconeogenesis BibTex
2008-09-10 R-GGA-352882 Glycolysis BibTex
2008-09-10 R-GGA-352832 Glucose transport BibTex
2008-09-10 R-GGA-372987 The tricarboxylic acid cycle BibTex
2008-09-10 R-GGA-372568 Amino acid metabolism BibTex
2008-09-10 R-GGA-373920 Pyruvate metabolism BibTex
2008-06-13 R-HSA-8964041 LDL remodeling BibTex
2008-06-03 R-HSA-352230 Amino acid transport across the plasma membrane BibTex
2008-05-12 R-HSA-8963676 Intestinal absorption BibTex
2008-05-12 R-HSA-8963678 Intestinal lipid absorption BibTex
2008-05-12 R-HSA-8964058 HDL remodeling BibTex
2008-05-12 R-HSA-8963896 HDL assembly BibTex
2008-05-12 R-HSA-8964011 HDL clearance BibTex
2007-07-10 R-HSA-199220 Vitamin B5 (pantothenate) metabolism BibTex
2007-04-30 R-HSA-8964026 Chylomicron clearance BibTex
2007-04-30 R-HSA-8963901 Chylomicron remodeling BibTex
2007-04-30 R-HSA-8964038 LDL clearance BibTex
2007-02-28 R-HSA-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol BibTex
2007-02-24 R-HSA-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol BibTex
2007-02-03 R-HSA-556833 Metabolism of lipids BibTex
2007-02-03 R-HSA-8978868 Fatty acid metabolism BibTex
2007-02-03 R-HSA-8979227 Triglyceride metabolism BibTex
2007-02-03 R-HSA-192456 Digestion of dietary lipid BibTex
2007-01-24 R-HSA-189451 Heme biosynthesis BibTex
2006-11-03 R-HSA-8981373 Intestinal hexose absorption BibTex
2006-11-03 R-HSA-189085 Digestion of dietary carbohydrate BibTex
2006-11-03 R-HSA-189200 Cellular hexose transport BibTex
2006-05-19 R-HSA-162589 Reverse Transcription of HIV RNA BibTex
2006-05-19 R-HSA-164525 Plus-strand DNA synthesis BibTex
2006-05-19 R-HSA-164516 Minus-strand DNA synthesis BibTex
2006-05-19 R-HSA-162592 Integration of provirus BibTex
2006-05-19 R-HSA-175567 Integration of viral DNA into host genomic DNA BibTex
2006-05-19 R-HSA-177539 Autointegration results in viral DNA circles BibTex
2006-05-19 R-HSA-164843 2-LTR circle formation BibTex
2006-05-16 R-HSA-162594 Early Phase of HIV Life Cycle BibTex
2006-04-19 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade BibTex
2006-04-19 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade BibTex
2006-04-19 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade BibTex
2006-02-20 R-HSA-174824 Plasma lipoprotein assembly, remodeling, and clearance BibTex
2006-02-20 R-HSA-8963899 Plasma lipoprotein remodeling BibTex
2006-02-20 R-HSA-8963898 Plasma lipoprotein assembly BibTex
2006-02-20 R-HSA-8963888 Chylomicron assembly BibTex
2005-07-20 R-HSA-71240 Tryptophan catabolism BibTex
2005-05-19 R-HSA-164378 PKA activation in glucagon signalling BibTex
2005-05-11 R-HSA-163685 Integration of energy metabolism BibTex
2005-05-08 R-HSA-163841 Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation BibTex
2005-05-02 R-HSA-163560 Triglyceride catabolism BibTex
2005-04-18 R-HSA-597592 Post-translational protein modification BibTex
2005-04-05 R-HSA-162791 Attachment of GPI anchor to uPAR BibTex
2005-04-05 R-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI) BibTex
2005-03-17 R-HSA-159854 Gamma-carboxylation, transport, and amino-terminal cleavage of proteins BibTex
2005-03-17 R-HSA-159740 Gamma-carboxylation of protein precursors BibTex
2005-03-17 R-HSA-159782 Removal of aminoterminal propeptides from gamma-carboxylated proteins BibTex
2005-03-17 R-HSA-159763 Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus BibTex
2004-08-24 R-HSA-140877 Formation of Fibrin Clot (Clotting Cascade) BibTex
2004-08-24 R-HSA-140875 Common Pathway of Fibrin Clot Formation BibTex
2004-08-24 R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation BibTex
2004-08-24 R-HSA-140834 Extrinsic Pathway of Fibrin Clot Formation BibTex
2004-02-09 R-HSA-73843 5-Phosphoribose 1-diphosphate biosynthesis BibTex
2004-01-22 R-HSA-109582 Hemostasis BibTex
2003-12-09 R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane BibTex
2003-11-03 R-HSA-71387 Metabolism of carbohydrates BibTex
2003-11-03 R-HSA-71291 Metabolism of amino acids and derivatives BibTex
2003-11-03 R-HSA-1428517 Aerobic respiration and respiratory electron transport BibTex
2003-06-24 R-HSA-70635 Urea cycle BibTex
2003-06-24 R-HSA-70921 Histidine catabolism BibTex
2003-06-24 R-HSA-70688 Proline catabolism BibTex
2003-06-24 R-HSA-70350 Fructose catabolism BibTex
2003-06-24 R-HSA-8964208 Phenylalanine metabolism BibTex
2003-06-24 R-HSA-71064 Lysine catabolism BibTex
2003-06-24 R-HSA-70895 Branched-chain amino acid catabolism BibTex
2003-04-14 R-HSA-71737 Pyrophosphate hydrolysis BibTex
Authored Reactions (919/919)
Date Identifier Reaction Reference
2023-12-20 R-HSA-9856548 MLXIPL:MLX binds ACACB gene promoter BibTex
2023-12-20 R-HSA-9856605 Transcriptional activation of ACACB by ChREBP:MLX BibTex
2023-12-20 R-HSA-9856546 MLXIPL:MLX binds FASN gene promoter BibTex
2023-12-20 R-HSA-9856550 MLXIPL:MLX binds ACACA gene promoter BibTex
2023-12-20 R-HSA-9856549 MLXIPL:MLX binds ACLY gene promoter BibTex
2023-12-20 R-HSA-9856539 MLXIPL:MLX binds PKLR gene promoter BibTex
2023-12-20 R-HSA-9856604 MLXIPL:MLX binds AGPAT1 gene promoter BibTex
2023-06-13 R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine BibTex
2023-06-13 R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT BibTex
2023-06-13 R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT BibTex
2023-06-13 R-HSA-9837337 DCAKD phosphorylates DP-CoA BibTex
2023-06-13 R-HSA-9837333 SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP BibTex
2022-09-23 R-HSA-9820566 ZnT5 transports zinc into the golgi apparatus BibTex
2022-09-23 R-HSA-9817575 ERO1B oxidizes P4HB BibTex
2022-05-27 R-HSA-9792608 SLC35D2 exchanges UDP-D-glucose for UMP BibTex
2021-11-29 R-HSA-9759209 LRP2 binds extracellular TCN2:RCbl BibTex
2021-11-29 R-HSA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome BibTex
2021-11-29 R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol BibTex
2021-07-02 R-HSA-9735775 Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose BibTex
2021-07-02 R-HSA-9735789 Defective PNP does not convert (deoxy)guanosine to guanine and (deoxy)ribose BibTex
2021-07-02 R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine BibTex
2021-07-02 R-HSA-9734193 Defective APRT does not convert adenine to AMP BibTex
2021-07-02 R-HSA-9734274 Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP BibTex
2021-05-21 R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine BibTex
2021-05-21 R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP BibTex
2021-05-21 R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP BibTex
2021-05-21 R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP BibTex
2021-05-18 R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP BibTex
2021-04-15 R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine BibTex
2021-04-15 R-HSA-9727349 XDH dehydrogenates xanthine to form urate BibTex
2020-01-09 R-MMU-9673827 Slc25a44 transports Leu, Ile and Val from cytosol to mitochondrial matrix BibTex
2020-01-06 R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe BibTex
2020-01-06 R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe BibTex
2020-01-02 R-HSA-9672770 SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix BibTex
2019-07-10 R-HSA-9653180 GABA translocates from cytosol to mitochondrial matrix BibTex
2018-12-07 R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 BibTex
2018-12-07 R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 BibTex
2018-12-07 R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 BibTex
2018-12-07 R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 BibTex
2018-12-07 R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 BibTex
2018-12-07 R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A BibTex
2018-12-07 R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 BibTex
2018-12-07 R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 BibTex
2018-12-07 R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 BibTex
2018-12-07 R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 BibTex
2018-12-07 R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 BibTex
2017-01-13 R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin BibTex
2017-01-13 R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer BibTex
2017-01-13 R-NUL-8955873 Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin BibTex
2017-01-13 R-HSA-8955869 Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin BibTex
2017-01-13 R-BTA-8955724 TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin BibTex
2017-01-13 R-HSA-8955706 TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin BibTex
2016-12-23 R-MMU-8953429 Pxmp2 trimer transports glycolate from cytosol to peroxisomal matrix BibTex
2016-12-23 R-HSA-8953430 PXMP2 trimer transports glycolate from cytosol to peroxisomal matrix BibTex
2016-11-24 R-HSA-8949413 HTMLYS translocates from the mitochondrial matrix to the cytosol BibTex
2016-11-23 R-HSA-8949399 CAR translocates from the cytosol to the mitochondrial intermembrane space BibTex
2016-05-09 R-HSA-8870352 SLC36A4 transports L-Trp from extracellular region to cytosol BibTex
2016-05-09 R-HSA-8870354 SLC36A4 transports extracellular L-Pro to the cytosol BibTex
2016-05-06 R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN BibTex
2016-05-06 R-HSA-8869603 SLC22A13 transports NCA from extracellular region to cytosol BibTex
2016-05-06 R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose BibTex
2016-05-06 R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN BibTex
2016-05-06 R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN BibTex
2016-05-06 R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN BibTex
2016-04-02 R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate BibTex
2016-02-06 R-HSA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) BibTex
2016-01-31 R-HSA-8855062 SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy BibTex
2015-12-17 R-MMU-8849847 St14 hydrolyzes and activates Klk5 BibTex
2015-12-10 R-HSA-8848585 AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM BibTex
2015-12-10 R-HSA-8848586 Transport of cytosolic HXOL to the peroxisome BibTex
2015-12-10 R-HSA-8848582 AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester BibTex
2015-12-10 R-HSA-8848580 DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG BibTex
2015-12-08 R-HSA-8848338 PNPLA4 hydrolyzes TAG BibTex
2015-12-08 R-HSA-8848339 PNPLA5 hydrolyzes TAG BibTex
2015-12-08 R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate BibTex
2015-12-03 R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho BibTex
2015-12-03 R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho BibTex
2015-12-01 R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA BibTex
2015-11-28 R-HSA-6813740 GDE1 hydrolyzes GroPIns BibTex
2015-11-28 R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine BibTex
2015-11-28 R-MMU-6814137 Gdpd5 hydrolyzes GPCho BibTex
2015-11-28 R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho BibTex
2015-11-28 R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho BibTex
2015-11-28 R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho BibTex
2015-11-28 R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho BibTex
2015-11-28 R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho BibTex
2015-11-28 R-HSA-6814132 GDPD5 hydrolyzes GPCho BibTex
2015-11-23 R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters BibTex
2015-11-20 R-HSA-6810076 DDO oxidizes D-Asp to OA BibTex
2015-11-20 R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM BibTex
2015-11-14 R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA BibTex
2015-11-13 R-HSA-6809808 ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA BibTex
2015-11-10 R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA BibTex
2015-11-10 R-HSA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA BibTex
2015-11-09 R-HSA-6807224 Furin cleaves pro-BGLAP to BGLAP BibTex
2015-11-09 R-HSA-6807229 Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus BibTex
2015-11-09 R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) BibTex
2015-11-09 R-HSA-6807826 LDHAL6B reduces PYR to LACT BibTex
2015-11-05 R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG BibTex
2015-11-05 R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG BibTex
2015-11-02 R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL BibTex
2015-11-02 R-HSA-6807052 EBP isomerizes ZYMSTNL to LTHSOL BibTex
2015-11-02 R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL BibTex
2015-11-02 R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL BibTex
2015-11-02 R-HSA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) BibTex
2015-11-02 R-HSA-6806674 UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) BibTex
2015-08-18 R-HSA-5659989 Defective TALDO1 does not transform SH7P, GA3P to Fru(6)P, E4P BibTex
2015-08-18 R-HSA-5659998 Defective TALDO1 does not transform Fru(6)P, E4P to SH7P, GA3P BibTex
2015-08-14 R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate BibTex
2015-08-14 R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate BibTex
2015-08-14 R-HSA-5662473 KGPDC decarboxylates 3-dehydro-L-gulonate to L-xylulose BibTex
2015-08-14 R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol BibTex
2015-08-14 R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose BibTex
2015-08-14 R-HSA-5662466 XYLB phosphorylates D-xylulose BibTex
2015-06-19 R-HSA-6784436 An unknown carrier transports mitochondrial glyoxylate to the cytosol BibTex
2015-06-19 R-HSA-6784434 An unknown carrier transports cytosolic glyoxylate to the peroxisome BibTex
2015-06-19 R-HSA-6784393 PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) BibTex
2015-06-19 R-HSA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate BibTex
2015-06-19 R-HSA-6784399 ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate BibTex
2015-06-19 R-HSA-6784402 Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde BibTex
2015-06-19 R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate BibTex
2015-06-19 R-HSA-6784213 Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix BibTex
2015-06-18 R-HSA-6783955 PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro BibTex
2015-06-18 R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro BibTex
2015-02-26 R-HSA-5662851 Defective DCXR does not reduce L-xylulose to xylitol BibTex
2015-02-24 R-HSA-5660015 Defective RPIA does not isomerize R5P to RU5P BibTex
2015-02-24 R-HSA-5660013 Defective RPIA does not isomerize RU5P to R5P BibTex
2015-02-15 R-HSA-5659899 Defective SI does not hydrolyze maltotriose BibTex
2015-02-15 R-HSA-5658001 Defective LCT does not hydrolyze Lac BibTex
2015-02-15 R-HSA-5659879 Defective SI does not hydrolyze iMal BibTex
2015-02-15 R-HSA-5659922 Defective SI does not hydrolyze Mal BibTex
2015-02-15 R-HSA-5659926 Defective SI does not hydrolyze Suc BibTex
2015-01-29 R-HSA-5656438 Defective ALDOB does not cleave Fru 1-P to GA and DHAP BibTex
2015-01-29 R-HSA-5656459 Defective KHK does not phosphorylate beta-D-fructose BibTex
2014-11-29 R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol BibTex
2014-11-29 R-HSA-5652195 SORD oxidizes D-sorbitol to Fru BibTex
2014-03-29 R-HSA-5358484 DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 BibTex
2014-03-29 R-HSA-5358494 DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 BibTex
2014-03-29 R-HSA-5358475 DPH6 ligates ammonium to diphthine-EEF2 BibTex
2014-03-29 R-HSA-5367022 DPH7 hydrolyzes a methyl group on Me-diphthine EEF2 BibTex
2014-03-29 R-SCE-5367021 Diphthamide biosynthesis protein 7 hydrolyzes a methyl group on Me-diphthine elongation factor 2 BibTex
2014-03-25 R-HSA-9036729 Defective GAA does not hydrolyze lysosomal glycogen BibTex
2014-03-25 R-HSA-9036727 GAA hydrolyzes lysosomal glycogen BibTex
2014-03-05 R-HSA-5336422 Clathrin-mediated endocytosis of DT:HBEGF:CD9 BibTex
2014-03-05 R-HSA-5336413 DT:HBEGF:CD9 is transported from clathrin-coated vesicle to endosome BibTex
2014-03-05 R-HSA-5336420 DT fragment B transports DT fragment A from target cell endosome membrane BibTex
2014-03-05 R-HSA-5336421 DT fragment A ADP-ribosylates target cell EEF BibTex
2014-03-05 R-HSA-5336417 DT A:B binds HBEGF and CD9 on the target cell surface BibTex
2014-02-11 R-HSA-5228411 Clathrin-mediated endocytosis of tetX HC:LC:gangliosides BibTex
2014-02-11 R-HSA-5228407 tetX HC:LC binds target cell-surface gangliosides BibTex
2014-02-11 R-HSA-5228408 Retrograde transport of internalized tetX HC:LC:gangliosides BibTex
2014-02-11 R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol BibTex
2014-02-11 R-HSA-5228578 tetX LC cleaves target cell VAMP2 BibTex
2013-12-13 R-HSA-5211224 Anthrax cya catalyzes the conversion of ATP to cAMP BibTex
2013-12-13 R-HSA-5211387 Anthrax lef cleaves target cell MAP2K7 (MEK7) BibTex
2013-12-13 R-HSA-5211356 Anthrax lef cleaves target cell MAP2K2 (MEK2) BibTex
2013-12-13 R-HSA-5211391 Anthrax lef cleaves target cell MAP2K4 (MEK4) BibTex
2013-12-13 R-HSA-5211400 Anthrax lef cleaves target cell MAP2K3 (MEK3) BibTex
2013-12-13 R-HSA-5211340 Anthrax lef cleaves target cell MAP2K1 (MEK1) BibTex
2013-12-13 R-HSA-5210921 pagA binds ANTXR1 BibTex
2013-12-13 R-HSA-5210935 Furin cleaves ANTXR1-bound pagA to yield pagA(197-794) BibTex
2013-12-13 R-HSA-5210909 ANTXR1-bound pagA(197-794) forms oligomers BibTex
2013-12-13 R-HSA-5210923 cya and lef bind to pagA(197-794):ANTXR1 oligomer BibTex
2013-12-13 R-HSA-5210944 Endocytosis of cya:lef:(pagA(197-794):ANTXR1 oligomer) (plasma membrane to endosome membrane) BibTex
2013-12-13 R-HSA-5210947 pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) BibTex
2013-12-13 R-HSA-5210943 pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) BibTex
2013-12-13 R-HSA-5211405 Anthrax lef cleaves target cell MAP2K6 (MEK6) BibTex
2013-12-13 R-HSA-5210918 pagA binds ANTXR2 BibTex
2013-12-13 R-HSA-5210912 Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) BibTex
2013-12-13 R-HSA-5210932 ANTXR2-bound pagA(197-794) forms oligomers BibTex
2013-12-13 R-HSA-5210892 cya and lef bind to pagA(197-794):ANTXR2 oligomer BibTex
2013-12-13 R-HSA-5210959 Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) BibTex
2013-07-19 R-HSA-3814838 Defective GYG1 is not autoglucosyolated BibTex
2013-07-19 R-HSA-3858506 Defective GYS2 does not transfer glucose to growing glycogen chains BibTex
2013-07-19 R-HSA-3791349 Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) BibTex
2013-07-19 R-HSA-3797226 Defective NHLRC1 does not ubiquitinate EPM2A (laforin) and PPP1R3C (PTG) (type 2B disease) BibTex
2013-07-19 R-HSA-3229118 Defective SLC37A4 does not exchange G6P and Pi across the ER membrane BibTex
2013-07-19 R-HSA-3282876 Defective G6PC3 does not hydrolyze glucose 6-phosphate BibTex
2013-07-19 R-HSA-3878762 Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver) BibTex
2013-07-19 R-HSA-3828061 Defective GYS1 does not transfer glucose to growing glycogen chains BibTex
2013-07-19 R-HSA-3274540 Defective G6PC does not hydrolyze glucose 6-phosphate BibTex
2013-07-19 R-HSA-3780995 NHLRC1 mediated ubiquitination of EPM2A (laforin) and PPP1RC3 (PTG) associated with glycogen-GYG2 BibTex
2013-07-19 R-HSA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 BibTex
2013-07-19 R-HSA-3781009 NHLRC1 mediated ubiquitination of EPM2A and PPP1RC3 associated with glycogen-GYG1 BibTex
2013-07-19 R-HSA-3780997 PPP1R3C binds to glycogen:GYG2:GYS2 BibTex
2013-07-19 R-HSA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 BibTex
2013-07-19 R-HSA-3781021 EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex BibTex
2013-07-19 R-HSA-3781023 PPP1R3C binds to glycogen:GYG1:GYS1 BibTex
2013-07-19 R-HSA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 BibTex
2013-07-19 R-HSA-3781001 EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex BibTex
2013-07-19 R-HSA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 BibTex
2013-05-15 R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG BibTex
2013-04-09 R-HSA-3257122 SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane BibTex
2012-10-05 R-HSA-2509816 NUDT16 hydrolyses IDP to IMP BibTex
2012-10-05 R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP BibTex
2012-10-05 R-HSA-2509838 ITPA hydrolyses dITP to dIMP BibTex
2012-10-05 R-HSA-2509827 ITPA hydrolyses ITP to IMP BibTex
2012-10-05 R-HSA-2509831 ITPA hydrolyses XTP to XMP BibTex
2012-07-06 R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP BibTex
2012-07-06 R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP BibTex
2012-07-06 R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP BibTex
2012-07-06 R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP BibTex
2012-07-06 R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP BibTex
2012-07-06 R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP BibTex
2012-07-06 R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP BibTex
2012-07-06 R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP BibTex
2012-07-06 R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP BibTex
2012-07-06 R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP BibTex
2012-06-07 R-HSA-2314678 ASA- acetylates PTGS1 BibTex
2012-06-07 R-HSA-2314686 ASA- acetylates PTGS2 BibTex
2012-06-06 R-HSA-2309779 PTGS2 dimer binds PTGS2 inhibitors BibTex
2012-06-04 R-HSA-2299725 PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol BibTex
2012-03-14 R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate BibTex
2012-03-14 R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate BibTex
2012-03-14 R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate BibTex
2012-03-14 R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate BibTex
2012-03-14 R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ BibTex
2012-03-14 R-HSA-2161500 abacavir [extracellular] => abacavir [cytosol] BibTex
2012-03-14 R-HSA-2162099 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP BibTex
2012-03-14 R-RNO-2162084 carbovir diphosphate + ATP => carbovir triphosphate + ADP BibTex
2012-03-14 R-SSC-2162073 carbovir monophosphate + ATP => carbovir diphosphate + ADP BibTex
2012-03-14 R-HSA-2161193 abacavir + AMP => abacavir monophosphate + adenosine BibTex
2012-03-14 R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine BibTex
2012-03-14 R-HSA-2162066 carbovir + IMP => carbovir monophosphate + inosine BibTex
2012-03-14 R-HSA-2162092 carbovir monophosphate + ATP => carbovir diphosphate + ADP BibTex
2012-03-14 R-HSA-2162096 carbovir diphosphate + ATP => carbovir triphosphate + ADP BibTex
2012-03-14 R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine BibTex
2012-03-05 R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV BibTex
2012-02-03 R-HSA-2064417 WWTR1 (TAZ) binds ZO-1 (TJP1) BibTex
2012-02-03 R-HSA-2064418 WWTR1 (TAZ) binds ZO-2 (TJP2) BibTex
2012-02-03 R-HSA-2028644 YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 BibTex
2012-02-03 R-HSA-2028583 Phosphorylation of YAP by LATS2 BibTex
2012-02-03 R-HSA-2028651 YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) BibTex
2012-02-03 R-HSA-2028724 AMOT proteins bind YAP1 BibTex
2012-02-03 R-HSA-2028598 Phosphorylation of YAP by LATS1 BibTex
2012-02-03 R-HSA-2028661 Phosphorylation of WWTR1 (TAZ) by LATS2 BibTex
2012-02-03 R-HSA-2028589 Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) BibTex
2012-02-03 R-HSA-2060328 Phosphorylation of WWTR1 (TAZ) by LATS1 BibTex
2012-02-03 R-HSA-2066299 DVL2 binds phosphorylated WWTR1 (TAZ) BibTex
2012-02-03 R-HSA-2028735 AMOT proteins bind WWTR1 (TAZ) BibTex
2012-02-03 R-HSA-2038398 KIBRA (WWC1) binds LATS proteins BibTex
2012-02-03 R-HSA-2028673 Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N BibTex
2012-02-03 R-HSA-2028679 Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N BibTex
2012-02-03 R-HSA-2028555 Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) BibTex
2012-02-03 R-HSA-2028675 Phosphorylation of MOB1A and B by p-STK3(MST2)/N BibTex
2012-02-03 R-HSA-2028670 Phosphorylation of MOB1A and B by p-STK4(MST1)/N BibTex
2012-02-03 R-HSA-2028626 Phosphorylated MOB1A proteins associate with LATS proteins BibTex
2012-02-03 R-HSA-2028629 Phosphorylation of MOB1A and B by p-STK4 (p-MST1) BibTex
2012-02-03 R-HSA-2028284 Phosphorylation of STK4 (MST1) and SAV1 by STK4 BibTex
2012-02-03 R-HSA-2028692 Cleavage of p-STK4 (p-MST1) by caspase 3 BibTex
2012-02-03 R-HSA-2064421 YAP1 binds ZO-2 (TJP2) BibTex
2012-02-03 R-HSA-2064406 Translocation of YAP1:ZO-2 (TJP2) to the nucleus BibTex
2012-02-03 R-HSA-2059926 NPHP4 protein binds LATS proteins BibTex
2012-02-03 R-HSA-2028697 Cleavage of p-STK3 (p-MST2) by caspase 3 BibTex
2012-02-03 R-HSA-2028591 Phosphorylation of STK3 (MST2) and SAV1 by STK3 BibTex
2012-02-03 R-HSA-2028635 Phosphorylation of MOB1A and B by p-STK3 (p-MST2) BibTex
2012-02-03 R-HSA-2032800 Expression of NPPA (ANF) BibTex
2012-02-03 R-MMU-2064924 Wwtr1 (Taz) binds Runx2 BibTex
2012-02-03 R-HSA-2064932 WWTR1 (TAZ) binds RUNX2 BibTex
2012-02-03 R-HSA-8871260 YAP1 binds TEAD2 BibTex
2012-02-03 R-HSA-8871265 YAP1 binds TEAD4 BibTex
2012-02-03 R-HSA-2032794 WWTR1 (TAZ), TBX5, and PCAF form a complex BibTex
2012-02-03 R-HSA-8871266 YAP1 binds TEAD3 BibTex
2012-02-03 R-HSA-2032770 Translocation of YAP1 to the nucleus BibTex
2012-02-03 R-HSA-2032775 YAP1 binds TEAD1 BibTex
2012-02-03 R-HSA-2032768 Translocation of WWTR1 (TAZ) to the nucleus BibTex
2012-02-03 R-HSA-2032781 WWTR1 (TAZ) binds TEAD BibTex
2010-07-08 R-HSA-909765 Mitochondrial uptake of beta-alanine BibTex
2010-07-08 R-RNO-909763 Mitochondrial uptake of beta-alanine BibTex
2010-07-08 R-HSA-909755 Mitochondrial uptake of (R)-3-aminoisobutyric acid BibTex
2010-07-08 R-RNO-909781 Mitochondrial uptake of (R)-3-aminoisobutyric acid BibTex
2010-07-08 R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine BibTex
2010-07-08 R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine BibTex
2010-07-08 R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine BibTex
2010-07-08 R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine BibTex
2010-07-05 R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate BibTex
2010-07-02 R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine BibTex
2010-07-02 R-HSA-901097 kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] BibTex
2010-07-02 R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu BibTex
2010-07-02 R-HSA-893609 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] BibTex
2010-07-02 R-HSA-888614 IDO2 dioxygenates L-Trp to NFK BibTex
2010-07-02 R-HSA-893597 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] BibTex
2010-06-26 R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] BibTex
2010-06-26 R-HSA-880007 (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 BibTex
2010-06-26 R-HSA-880002 (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate BibTex
2010-06-26 R-HSA-880033 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde BibTex
2010-06-26 R-HSA-880050 (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 BibTex
2010-03-15 R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA BibTex
2010-03-15 R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA BibTex
2010-03-15 R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA BibTex
2010-03-15 R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA BibTex
2010-03-15 R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] BibTex
2010-03-15 R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA BibTex
2010-03-15 R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA BibTex
2010-03-15 R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA BibTex
2010-02-18 R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala BibTex
2010-02-18 R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR BibTex
2010-02-18 R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] BibTex
2010-02-18 R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] BibTex
2010-02-18 R-HSA-508561 alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate BibTex
2010-02-18 R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] BibTex
2010-02-18 R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ BibTex
2010-02-18 R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ BibTex
2010-02-18 R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] BibTex
2010-02-18 R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) BibTex
2010-02-06 R-HSA-482621 (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) BibTex
2010-02-06 R-HSA-482619 (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) BibTex
2010-02-06 R-HSA-482804 (d)NDP + ATP <=> (d)NTP + ADP (NME4) BibTex
2010-02-06 R-HSA-482812 (d)NTP + ADP <=> (d)NDP + ATP (NME4) BibTex
2010-01-22 R-HSA-453339 poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] BibTex
2010-01-22 R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP BibTex
2010-01-22 R-HSA-453356 PYGB dimer, b form + 2 AMP <=> PYGB b dimer:AMP complex BibTex
2010-01-22 R-HSA-453346 PYGB b dimer:AMP complex <=> PGYB dimer, b form + 2 AMP BibTex
2010-01-22 R-HSA-453342 PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex BibTex
2010-01-22 R-HSA-453338 PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP BibTex
2010-01-22 R-HSA-453358 poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] BibTex
2009-12-26 R-HSA-450984 IDH2 dimer decarboxylates isocitrate BibTex
2009-12-26 R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ BibTex
2009-12-12 R-HSA-450092 GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP BibTex
2009-12-12 R-HSA-450088 GLUT1 tetramer binds 4xATP BibTex
2009-12-12 R-HSA-450095 GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region BibTex
2009-12-10 R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] BibTex
2009-12-09 R-HSA-449872 acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] BibTex
2009-12-09 R-HSA-449911 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] BibTex
2009-08-21 R-HSA-428262 ACER3 hydrolyzes phytoceramide BibTex
2009-08-21 R-HSA-428260 DEGS2 oxygenates dihydroceramide BibTex
2009-08-21 R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid BibTex
2009-08-21 R-HSA-428123 KDSR reduces 3-ketosphingoid BibTex
2009-08-21 R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine BibTex
2009-08-21 R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) BibTex
2009-08-21 R-HSA-428259 DEGS1 dehydrogenates dihydroceramide BibTex
2009-08-21 R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates BibTex
2009-08-21 R-HSA-428273 SPHK1 phosphorylates sphingoid BibTex
2009-08-21 R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate BibTex
2009-08-21 R-HSA-9695949 SPHK2 phosphorylates sphingoid BibTex
2009-08-21 R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate BibTex
2009-08-21 R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) BibTex
2009-08-21 R-HSA-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus BibTex
2009-08-21 R-HSA-429699 CERT1-2 complex binds ceramide BibTex
2009-08-21 R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 BibTex
2009-08-21 R-HSA-429732 Multiphospho-CERT1-2 binds PPM1L, VAPA/B BibTex
2009-08-21 R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 BibTex
2009-08-21 R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 BibTex
2009-08-21 R-HSA-429694 CERT1-2 complex dissociates BibTex
2009-08-21 R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates BibTex
2009-08-21 R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide BibTex
2009-08-21 R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide BibTex
2009-05-19 R-GGA-421471 hydroxymethylbilane => uroporphyrinogen I + H2O BibTex
2009-05-19 R-GGA-421459 uroporphyrinogen I => coproporphyrinogen I + 4 CO2 BibTex
2009-05-19 R-GGA-421485 Translocation of coproporphyrinogen III from the cytosol to the mitochondrial intermembrane space BibTex
2009-05-19 R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O BibTex
2009-05-19 R-GGA-421454 Transport of protoporphyrin IX from the mitochondrial intermembrane space into the mitochondrial matrix BibTex
2009-05-19 R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ BibTex
2009-05-19 R-GGA-421508 Synthesis of ALAS1 nascent polypeptide BibTex
2009-05-19 R-GGA-421453 Mitochondrial uptake and processing of ALAS1 BibTex
2009-05-19 R-GGA-421495 Synthesis of ALAS2 nascent polypeptide BibTex
2009-05-19 R-GGA-421457 Mitochondrial uptake and processing of ALAS2 BibTex
2009-05-19 R-GGA-421493 succinyl-CoA + glycine => delta-aminolevulinate + CoA SH + CO2 BibTex
2009-05-19 R-GGA-421517 Transport of delta-aminolevulinate from the mitochondrial matrix to the cytosol BibTex
2009-05-19 R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O BibTex
2009-05-19 R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 BibTex
2009-05-19 R-GGA-421482 hydroxymethylbilane => uroporphyrinogen III + H2O BibTex
2009-05-19 R-GGA-421515 uroporphyrinogen III => coproporphyrinogen III + 4 CO2 BibTex
2009-05-19 R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 BibTex
2009-05-16 R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate BibTex
2009-05-16 R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ BibTex
2009-05-15 R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ BibTex
2009-05-15 R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ BibTex
2009-05-15 R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate BibTex
2009-05-15 R-GGA-421174 inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate BibTex
2009-05-15 R-GGA-421197 adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate BibTex
2009-05-15 R-GGA-421201 inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate BibTex
2009-05-01 R-GGA-419461 orotidine 5'-monophosphate => uridine 5'-monophosphate + CO2 BibTex
2009-05-01 R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate BibTex
2009-05-01 R-GGA-419451 carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate BibTex
2009-05-01 R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O BibTex
2009-05-01 R-GGA-419452 (S)-dihydroorotate + ubiquinone => orotate + ubiquinol BibTex
2009-05-01 R-GGA-419462 orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate BibTex
2009-04-29 R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate BibTex
2009-04-29 R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate BibTex
2009-04-29 R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate BibTex
2009-04-29 R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate BibTex
2009-04-29 R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate BibTex
2009-04-29 R-GGA-419214 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) BibTex
2009-04-29 R-GGA-419223 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate BibTex
2009-04-29 R-GGA-419255 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate BibTex
2009-04-29 R-GGA-419254 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate BibTex
2009-04-29 R-GGA-419253 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O BibTex
2009-03-16 R-HSA-390281 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH BibTex
2009-03-16 R-HSA-390284 propionyl-CoA + carnitine => propionylcarnitine + CoASH BibTex
2009-03-16 R-HSA-390291 acetyl-CoA + carnitine => acetylcarnitine + CoASH BibTex
2009-03-16 R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH BibTex
2009-03-16 R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) BibTex
2009-03-16 R-HSA-389897 Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA BibTex
2009-03-16 R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA BibTex
2009-03-16 R-HSA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA BibTex
2009-03-16 R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ BibTex
2009-03-16 R-HSA-390224 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA BibTex
2009-03-16 R-HSA-390276 4,8,12-trimethyltridecanoyl-CoA + 2 O2 + 2 H2O + 2 NAD+ + 2 CoASH => 4,8-dimethylnonanoyl-CoA + 2 H2O2 + 2 NADH + 2 H+ + acetyl-CoA + propionyl-CoA BibTex
2009-03-16 R-HSA-390250 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA BibTex
2009-03-16 R-HSA-390302 tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA BibTex
2009-03-16 R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA BibTex
2009-03-16 R-HSA-390256 hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 BibTex
2009-03-16 R-HSA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA BibTex
2009-03-16 R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA BibTex
2009-03-16 R-HSA-390425 FAR1 reduces PalmCoA to HXOL BibTex
2009-03-16 R-HSA-390438 FAR2 reduces PalmCoA to HXOL BibTex
2009-03-16 R-HSA-75879 palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH BibTex
2009-03-16 R-HSA-390427 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate BibTex
2009-03-16 R-HSA-390402 Movement of O-hexadecylglycerone phosphate from the peroxisomal matrix to the cytosol BibTex
2009-03-16 R-HSA-75883 DHRS7B reduces GO3P to HXDG3P BibTex
2009-01-12 R-HSA-389862 Conversion of glyoxylate to oxalate BibTex
2009-01-12 R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate BibTex
2009-01-12 R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] BibTex
2009-01-12 R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ BibTex
2009-01-12 R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ BibTex
2009-01-11 R-HSA-389580 formyl-CoA + H2O => formate + CoASH BibTex
2009-01-11 R-HSA-389611 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA BibTex
2009-01-11 R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate BibTex
2009-01-11 R-HSA-389632 pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate BibTex
2009-01-11 R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 BibTex
2009-01-11 R-HSA-389622 phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate BibTex
2009-01-11 R-HSA-389652 PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP BibTex
2009-01-08 R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ BibTex
2009-01-08 R-HSA-390347 Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane BibTex
2009-01-08 R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ BibTex
2008-11-29 R-HSA-380216 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380222 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380158 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380157 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380176 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380240 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380241 glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380177 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380234 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380203 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380200 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380201 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380233 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380239 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380227 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380224 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380198 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379994 methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379844 histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379974 leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380002 threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379980 tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379887 cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379982 glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379977 tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380008 lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379848 phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380042 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379861 glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379893 isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380048 glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379996 asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379993 arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379865 proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379864 alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379992 serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379867 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380229 aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380199 valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-380170 tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate BibTex
2008-11-29 R-HSA-379432 SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu BibTex
2008-11-29 R-HSA-379426 SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine BibTex
2008-11-29 R-HSA-378513 SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate BibTex
2008-11-29 R-HSA-379415 SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane BibTex
2008-09-13 R-HSA-376851 SLC25A11 exchanges 2-OG and MAL BibTex
2008-09-13 R-HSA-372843 SLC25A10 mediates exchange of malate and phosphate BibTex
2008-09-13 R-HSA-372819 PCK2 phosphorylates OA to yield PEP BibTex
2008-09-13 R-HSA-372449 SLC25A1 may exchange mitochondrial PEP for cytosolic anion BibTex
2008-09-13 R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp BibTex
2008-09-13 R-HSA-372480 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] BibTex
2008-09-10 R-GGA-376887 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] BibTex
2008-09-10 R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate BibTex
2008-09-10 R-GGA-352908 fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP BibTex
2008-09-10 R-GGA-376886 Efflux of glucose and orthophosphate from the endoplasmic reticulum BibTex
2008-09-10 R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] BibTex
2008-09-10 R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] BibTex
2008-09-10 R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ BibTex
2008-09-10 R-GGA-352864 glucose [extracellular] <=> glucose [cytosol] BibTex
2008-09-10 R-GGA-376884 glucose 6-phosphate [cytosol] => glucose 6-phosphate [endoplasmic reticulum lumen] BibTex
2008-09-10 R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate BibTex
2008-09-10 R-GGA-352867 glucose [cytosol] <=> glucose [extracellular] BibTex
2008-09-10 R-GGA-352840 glucose + ATP => glucose 6-phosphate + ADP BibTex
2008-09-10 R-GGA-352893 glucose 6-phosphate <=> fructose 6-phosphate BibTex
2008-09-10 R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate BibTex
2008-09-10 R-GGA-352872 fructose 6-phosphate <=> glucose 6-phosphate BibTex
2008-09-10 R-GGA-352945 fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP BibTex
2008-09-10 R-GGA-352946 fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + glyceraldehyde 3-phosphate BibTex
2008-09-10 R-GGA-352961 dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate BibTex
2008-09-10 R-GGA-352927 dihydroxyacetone phosphate <=> glyceraldehyde 3-phosphate BibTex
2008-09-10 R-GGA-352914 glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate BibTex
2008-09-10 R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ BibTex
2008-09-10 R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate BibTex
2008-09-10 R-GGA-353039 1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP BibTex
2008-09-10 R-GGA-353023 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP BibTex
2008-09-10 R-GGA-352994 3-phosphoglycerate <=> 2-phosphoglycerate BibTex
2008-09-10 R-GGA-353014 2-phosphoglycerate <=> 3-phosphoglycerate BibTex
2008-09-10 R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O BibTex
2008-09-10 R-GGA-372724 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] BibTex
2008-09-10 R-GGA-372723 phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] BibTex
2008-09-10 R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ BibTex
2008-09-10 R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP BibTex
2008-09-10 R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate BibTex
2008-09-10 R-GGA-372741 oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] BibTex
2008-09-10 R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ BibTex
2008-09-10 R-GGA-372852 malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix] BibTex
2008-09-10 R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ BibTex
2008-09-10 R-GGA-373145 fumarate + H2O <=> malate BibTex
2008-09-10 R-GGA-373147 succinate + FAD <=> fumarate + FADH2 BibTex
2008-09-10 R-GGA-372980 succinylCoA + GDP + Pi <=> succinate + CoASH + GTP BibTex
2008-09-10 R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ BibTex
2008-09-10 R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ BibTex
2008-09-10 R-GGA-373015 citrate <=> isocitrate BibTex
2008-09-10 R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA BibTex
2008-09-10 R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ BibTex
2008-09-10 R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] BibTex
2008-09-10 R-GGA-372977 succinylCoA + ADP + Pi <=> succinate + CoASH + ATP BibTex
2008-09-10 R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ BibTex
2008-09-10 R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate BibTex
2008-09-10 R-GGA-372717 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) BibTex
2008-09-10 R-GGA-372719 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate BibTex
2008-09-10 R-GGA-372726 aspartate [mitochondrial matrix] + glutamate [cytosol] <=> aspartate [cytosol] + glutamate [mitochondrial matrix] BibTex
2008-09-10 R-GGA-372559 aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate BibTex
2008-09-10 R-GGA-372564 oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) BibTex
2008-09-10 R-GGA-372742 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] BibTex
2008-07-17 R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol BibTex
2008-07-17 R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region BibTex
2008-06-20 R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix BibTex
2008-06-20 R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix BibTex
2008-06-13 R-CFA-265529 NPC1L1-mediated cholesterol uptake BibTex
2008-06-13 R-HSA-266350 CETP-mediated lipid exchange: LDL gains cholesterol ester BibTex
2008-06-03 R-HSA-352059 SLC6A15-mediated amino acid uptake BibTex
2008-06-03 R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine BibTex
2008-06-03 R-HSA-352029 SLC6A12 (BGT-1)-mediated uptake of GABA and betaine BibTex
2008-06-03 R-HSA-352379 SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane BibTex
2008-06-03 R-HSA-352385 SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane BibTex
2008-06-03 R-HSA-352136 SLC38A4 (ATA3)-mediated uptake of arginine and lysine BibTex
2008-06-03 R-HSA-376200 SLC7A10-mediated uptake of small neutral amino acids BibTex
2008-06-03 R-HSA-352158 SLC16A10-mediated uptake of aromatic amino acids BibTex
2008-06-03 R-HSA-375768 SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids BibTex
2008-06-03 R-HSA-351963 SLC6A18 transports Gly from extracellular region to cytosol BibTex
2008-06-03 R-HSA-352347 SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine BibTex
2008-06-03 R-HSA-375770 SLC7A3 (CAT-3)-mediated uptake of cationic amino acids BibTex
2008-06-03 R-HSA-352103 SLC43A1 (LAT3)-mediated uptake of large neutral amino acids BibTex
2008-06-03 R-HSA-375776 SLC7A1 (CAT-1)-mediated uptake of cationic amino acids BibTex
2008-06-03 R-HSA-352354 SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine BibTex
2008-06-03 R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol BibTex
2008-06-03 R-HSA-352108 SLC38A2 (ATA2)-mediated uptake of neutral amino acids BibTex
2008-06-03 R-HSA-352364 SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine BibTex
2008-06-03 R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine BibTex
2008-06-03 R-HSA-375790 SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids BibTex
2008-06-03 R-HSA-352232 SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol BibTex
2008-06-03 R-HSA-352107 SLC43A2 (LAT4)-mediated uptake of large neutral amino acids BibTex
2008-06-03 R-HSA-352052 SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol BibTex
2008-06-03 R-HSA-352119 SLC38A1 (ATA1)-mediated uptake of neutral amino acids BibTex
2008-06-03 R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine BibTex
2008-06-03 R-HSA-375473 SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol BibTex
2008-06-03 R-HSA-351987 SLC6A6-mediated uptake of taurine and beta-alanine BibTex
2008-06-03 R-HSA-352371 SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine BibTex
2008-06-03 R-HSA-352191 SLC7A8-mediated uptake of neutral amino acids BibTex
2008-06-03 R-HSA-375487 SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol BibTex
2008-05-12 R-HSA-265545 NPC1L1-mediated phytosterol uptake BibTex
2008-05-12 R-HSA-265443 NPC1L1-mediated cholesterol uptake BibTex
2008-05-12 R-HSA-265456 NPC1L1 binds ezetimibe BibTex
2008-05-12 R-HSA-264834 Endocytosis and degradation of apoA-I BibTex
2008-05-12 R-HSA-264848 apoA-I binds to CUBN:AMN BibTex
2008-05-12 R-HSA-174690 TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III BibTex
2008-05-12 R-HSA-266299 Spherical HDL binds membrane-associated free cholesterol and phospholipids BibTex
2008-05-12 R-HSA-266303 Spherical HDL binds C and E apolipoproteins BibTex
2008-05-12 R-HSA-349404 CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex BibTex
2008-05-12 R-HSA-266089 Discoidal HDL binds membrane-associated free cholesterol BibTex
2008-05-12 R-HSA-264695 cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) BibTex
2008-05-12 R-HSA-264679 Serum albumin binds 2-lysophosphatidylcholine BibTex
2008-05-12 R-HSA-266310 LCAT:spherical HDL complex <=> LCAT + spherical HDL BibTex
2008-05-12 R-HSA-266315 LCAT + spherical HDL <=> LCAT:spherical HDL complex BibTex
2008-05-12 R-HSA-264678 LCAT + discoidal HDL <=> LCAT:discoidal HDL complex BibTex
2008-05-12 R-HSA-264689 LCAT:discoidal HDL complex <=> LCAT + discoidal HDL BibTex
2008-05-12 R-HSA-266328 CETP-mediated lipid exchange: spherical HDL gains triacylglycerol BibTex
2008-05-12 R-HSA-174660 nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron BibTex
2008-05-12 R-HSA-349637 spherical HDL and SR-BI receptor form a complex at the cell surface BibTex
2008-05-12 R-HSA-349638 Disassembly of SR-BI-bound spherical HDL BibTex
2008-05-12 R-HSA-349657 pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle BibTex
2008-05-12 R-HSA-216756 Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle BibTex
2008-05-12 R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane BibTex
2008-05-12 R-HSA-264758 BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 BibTex
2008-05-12 R-HSA-216727 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 BibTex
2008-05-12 R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane BibTex
2008-05-12 R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface BibTex
2008-05-12 R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region BibTex
2007-07-19 R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD BibTex
2007-07-19 R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD BibTex
2007-07-18 R-HSA-200318 creatine + ATP => phosphocreatine + ADP [CKB,CKM] BibTex
2007-07-18 R-HSA-200326 creatine + ATP => phosphocreatine + ADP [CK octamer] BibTex
2007-07-18 R-HSA-200396 Creatine transport across the plasma membrane BibTex
2007-07-18 R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate BibTex
2007-07-11 R-HSA-199626 SLC19A2/3 transport extracellular THMN to cytosol BibTex
2007-07-10 R-HSA-199216 SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix BibTex
2007-07-10 R-HSA-199206 SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol BibTex
2007-07-10 R-HSA-199203 PANK1/3 phosphorylate PanK BibTex
2007-07-10 R-HSA-199219 SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol BibTex
2007-07-10 R-HSA-199202 Phosphopantetheine conjugation of the ACP domain of FAS BibTex
2007-07-05 R-HSA-198845 CYB5A:heme reduces Asc.- to AscH- BibTex
2007-07-05 R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme BibTex
2007-07-05 R-HSA-198870 SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol BibTex
2007-07-05 R-HSA-198818 SLC2A1,3 transports DeHA from extracellular region to cytosol BibTex
2007-07-05 R-HSA-198813 GSTO dimers reduce DeHA to AscH- BibTex
2007-06-22 R-HSA-198563 IDO1 dioxygenates L-Trp to NFK BibTex
2007-06-22 R-HSA-198458 Efflux of Glc from the endoplasmic reticulum BibTex
2007-06-22 R-HSA-198513 SLC7A4 exchanges G6P for Pi across the ER membrane BibTex
2007-06-22 R-HSA-198440 SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane BibTex
2007-04-30 R-HSA-174808 chylomicron remnant:apoE:LDLR complex [coated vesicle membrane] => chylomicron remnant:apoE:LDLR complex [endosome membrane] BibTex
2007-04-30 R-HSA-174624 chylomicron remnant:apoE:LDLR complex => chylomicron remnant:apoE + LDLR BibTex
2007-04-30 R-HSA-174657 chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex BibTex
2007-04-30 R-HSA-174706 chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) BibTex
2007-04-30 R-HSA-174739 chylomicron remnant + apoE => chylomicron remnant:apoE complex BibTex
2007-04-30 R-HSA-174757 chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols BibTex
2007-04-30 R-HSA-174731 Degradation of newly synthesized ApoB-48 BibTex
2007-04-30 R-HSA-174741 ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron BibTex
2007-04-30 R-HSA-174587 nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] BibTex
2007-04-30 R-HSA-174786 ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex BibTex
2007-04-30 R-HSA-171122 LDL + LDLR => LDL:LDLR complex BibTex
2007-04-30 R-HSA-171141 LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) BibTex
2007-04-30 R-HSA-171059 LDLR:LDL complex [coated vesicle membrane] => LDLR:LDL complex [endosome membrane] BibTex
2007-04-30 R-HSA-171106 LDLR:LDL complex => LDLR + LDL BibTex
2007-04-30 R-HSA-171087 LDLR [endosome membrane] => LDLR [plasma membrane] BibTex
2007-04-21 R-HSA-196417 Reduction of desmosterol to cholesterol BibTex
2007-04-21 R-HSA-195690 Zymosterol is isomerized to cholesta-7,24-dien-3beta-ol BibTex
2007-04-21 R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol BibTex
2007-04-21 R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol BibTex
2007-04-21 R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol BibTex
2007-04-21 R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) BibTex
2007-04-21 R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) BibTex
2007-04-21 R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] BibTex
2007-04-21 R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] BibTex
2007-04-21 R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol BibTex
2007-04-21 R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one BibTex
2007-04-21 R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol BibTex
2007-03-10 R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol BibTex
2007-03-10 R-HSA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol BibTex
2007-03-10 R-HSA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol BibTex
2007-03-10 R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol BibTex
2007-03-10 R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region BibTex
2007-03-10 R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A BibTex
2007-02-28 R-HSA-193801 Influx of 27-hydroxycholesterol BibTex
2007-02-28 R-HSA-193812 Efflux of 27-hydroxycholesterol BibTex
2007-02-28 R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one BibTex
2007-02-28 R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol BibTex
2007-02-28 R-HSA-193832 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-02-28 R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one BibTex
2007-02-28 R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol BibTex
2007-02-28 R-HSA-193808 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-02-28 R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one BibTex
2007-02-24 R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-02-24 R-HSA-193767 Influx of 24-hydroxycholesterol BibTex
2007-02-24 R-HSA-193776 Efflux of 24-hydroxycholesterol BibTex
2007-02-24 R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one BibTex
2007-02-24 R-HSA-193792 CYP27A1 27-hydroxylates 5?-CHOL3?,7?,24(s)-triol BibTex
2007-02-24 R-HSA-193715 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-02-24 R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol BibTex
2007-02-24 R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one BibTex
2007-02-24 R-HSA-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA BibTex
2007-02-24 R-HSA-193753 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-02-24 R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-02-24 R-HSA-193786 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-02-24 R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) BibTex
2007-02-24 R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al BibTex
2007-02-24 R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-02-24 R-HSA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA BibTex
2007-02-24 R-HSA-193761 25(R) TetraHCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-02-24 R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-02-24 R-HSA-193722 TetraHCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-02-24 R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) BibTex
2007-02-24 R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al BibTex
2007-02-24 R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol BibTex
2007-02-24 R-HSA-193774 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-02-24 R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol BibTex
2007-02-24 R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one BibTex
2007-02-18 R-HSA-193399 Cholate is translocated from the peroxisomal matrix to the cytosol BibTex
2007-02-18 R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH BibTex
2007-02-18 R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region BibTex
2007-02-03 R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) BibTex
2007-02-03 R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 BibTex
2007-02-03 R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) BibTex
2007-02-03 R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase BibTex
2007-02-03 R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase BibTex
2007-02-03 R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) BibTex
2007-01-24 R-HSA-190141 ALAD binds to Pb2+ BibTex
2007-01-24 R-HSA-189488 UROS transforms HMB to URO3 BibTex
2007-01-24 R-HSA-189425 UROD decarboxylates URO3 to COPRO3 BibTex
2007-01-24 R-HSA-189467 Cytosolic COPRO3 translocates to mitochondrial intermembrane space BibTex
2007-01-24 R-HSA-189421 CPO transforms COPRO3 to PPGEN9 BibTex
2007-01-24 R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 BibTex
2007-01-24 R-HSA-189457 Mitochondrial intermembrane PRIN9 translocates to mitochondrial matrix BibTex
2007-01-24 R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme BibTex
2007-01-24 R-HSA-189456 Mitochondrial dALA translocates to cytosol BibTex
2007-01-24 R-HSA-189439 ALAD condenses 2 dALAs to form PBG BibTex
2007-01-24 R-HSA-189406 4 PBGs bind to form HMB BibTex
2007-01-24 R-HSA-190168 HMBL spontaneously transforms to URO1 BibTex
2007-01-24 R-HSA-190182 UROD decarboxylates URO1 to COPRO1 BibTex
2007-01-24 R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA BibTex
2006-11-03 R-HSA-189242 SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region BibTex
2006-11-03 R-HSA-189222 SLC2A5 transports fructose from extracellular region to cytosol BibTex
2006-11-03 R-OCU-189019 trehalose + H2O => 2 D-glucose BibTex
2006-11-03 R-HSA-188985 trehalose + H2O => 2 D-glucose BibTex
2006-11-03 R-HSA-189069 sucrose + H2O => glucose + fructose BibTex
2006-11-03 R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) BibTex
2006-11-03 R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) BibTex
2006-11-03 R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose BibTex
2006-11-03 R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) BibTex
2006-11-03 R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase BibTex
2006-11-03 R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase BibTex
2006-11-03 R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) BibTex
2006-11-03 R-HSA-189062 lactose + H2O => D-glucose + D-galactose BibTex
2006-11-03 R-HSA-189208 SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol BibTex
2006-05-19 R-HSA-175117 1-LTR circle formation BibTex
2006-05-19 R-HSA-164523 Transesterification to connect viral DNA 3' ends to host DNA 5' ends BibTex
2006-05-19 R-HSA-164506 Gap repair completes provirus integration BibTex
2006-05-19 R-HSA-164514 Integrase binds viral DNA ends BibTex
2006-05-19 R-HSA-173115 Formation of Pre-Integration Complex (PIC) BibTex
2006-05-19 R-HSA-8951690 Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 BibTex
2006-05-19 R-HSA-182876 Removal of plus-strand flap and gap closure complete synthesis of linear duplex viral DNA BibTex
2006-05-19 R-HSA-164505 Synthesis of full-length duplex viral DNA with a discontinuous plus strand BibTex
2006-05-19 R-HSA-164512 Second strand transfer by annealing complementary PBS sequences BibTex
2006-05-19 R-HSA-173769 RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers BibTex
2006-05-19 R-HSA-164513 3' PPT-primed initiation of plus-strand DNA synthesis BibTex
2006-05-19 R-HSA-182795 RNase H-mediated degradation of the template strand BibTex
2006-05-19 R-HSA-164528 RNase H-mediated cleavage of the template strand BibTex
2006-05-19 R-HSA-164520 Minus strand DNA synthesis resumes BibTex
2006-05-19 R-HSA-164503 First strand transfer mediated by Repeated (R) sequence BibTex
2006-05-19 R-HSA-182859 RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex BibTex
2006-05-19 R-HSA-164519 RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex BibTex
2006-05-19 R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) BibTex
2006-05-19 R-HSA-164527 Annealing of 3'-end of unwound transfer RNA primer with genomic RNA BibTex
2006-05-19 R-HSA-175250 Suicidal integration leading to smaller circles of viral DNA BibTex
2006-05-19 R-HSA-162590 Import of PIC to the Host Nucleus BibTex
2006-05-19 R-HSA-164522 Terminal (3' end) cleavage of viral DNA BibTex
2006-05-19 R-HSA-164845 Suicidal integration leading to inverted circle formation BibTex
2006-05-19 R-HSA-175174 Association of Ku heterodimer with viral DNA ends BibTex
2006-05-19 R-HSA-175258 2-LTR formation due to circularization of viral DNA BibTex
2006-05-19 R-HSA-175177 Association of XRCC4:DNA ligase IV complex with viral DNA ends BibTex
2006-05-19 R-HSA-175108 Target DNA binding BibTex
2006-04-19 R-HSA-168951 TLR1:TLR2 is recruited to ligand:CD14 BibTex
2006-04-19 R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 BibTex
2005-07-26 R-HSA-164967 Unknown carnitine exporter transports CAR from the cytosol to the extracellular space BibTex
2005-07-26 R-HSA-165026 OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol BibTex
2005-07-20 R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ BibTex
2005-07-20 R-RNO-71234 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 [rat] BibTex
2005-07-20 R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine BibTex
2005-07-20 R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde BibTex
2005-07-20 R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 BibTex
2005-07-20 R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ BibTex
2005-07-20 R-HSA-893583 kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate BibTex
2005-07-20 R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] BibTex
2005-07-20 R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK BibTex
2005-07-20 R-HSA-71189 AFMID hydrolyses NFK to L-KYN BibTex
2005-07-20 R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O BibTex
2005-05-08 R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) BibTex
2005-05-08 R-HSA-163843 Furin cleaves pro-GAS6 to GAS6 BibTex
2005-05-02 R-RNO-163609 phosphorylated perilipin + H2O -> perilipin + orthophosphate BibTex
2005-05-02 R-HSA-163568 phosphorylated perilipin + H2O -> perilipin + orthophosphate BibTex
2005-05-02 R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid BibTex
2005-05-02 R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid BibTex
2005-05-02 R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid BibTex
2005-05-02 R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid BibTex
2005-05-02 R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid BibTex
2005-05-02 R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid BibTex
2005-05-02 R-RNO-163523 phosphorylated HSL dimer + FABPA -> phosphorylated HSL dimer:FABPA complex BibTex
2005-05-02 R-HSA-163549 phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex BibTex
2005-05-02 R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid BibTex
2005-05-02 R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid BibTex
2005-05-02 R-RNO-163398 phosphorylated HSL + H2O -> HSL + orthophosphate BibTex
2005-05-02 R-HSA-163489 phosphorylated HSL + H2O -> HSL + orthophosphate BibTex
2005-05-02 R-RNO-163597 Phosphorylated HSL dimer translocates from the cytosol to the lipid particle BibTex
2005-05-02 R-MMU-163422 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP BibTex
2005-05-02 R-RNO-163601 perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP BibTex
2005-05-02 R-MMU-163511 perilipin:CGI-58 complex -> perilipin + CGI-58 BibTex
2005-05-02 R-HSA-163539 perilipin:CGI-58 complex -> perilipin + CGI-58 BibTex
2005-05-02 R-HSA-163418 perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP BibTex
2005-05-02 R-RNO-163519 2 phosphorylated HSL monomers -> phosphorylated HSL dimer BibTex
2005-05-02 R-RNO-163472 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP BibTex
2005-05-02 R-HSA-163416 hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP BibTex
2005-05-02 R-HSA-163554 Phosphorylated HSL dimer translocates from the cytosol to the lipid particle BibTex
2005-05-02 R-HSA-163602 2 phosphorylated HSL monomers -> phosphorylated HSL dimer BibTex
2005-04-05 R-HSA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid BibTex
2005-04-05 R-HSA-162836 uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide BibTex
2005-04-05 R-HSA-162797 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI BibTex
2005-04-05 R-HSA-162840 Reorientation of glucosaminyl-acyl-PI in the endoplasmic reticulum membrane BibTex
2005-04-05 R-MMU-162863 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol BibTex
2005-04-05 R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP BibTex
2005-04-05 R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate BibTex
2005-04-05 R-HSA-162683 glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH BibTex
2005-04-05 R-HSA-162830 glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate BibTex
2005-04-05 R-HSA-162798 mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol BibTex
2005-04-05 R-HSA-162873 (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate BibTex
2005-04-05 R-HSA-162821 mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate BibTex
2005-04-05 R-HSA-163069 mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (acyl-GPI) + diacylglycerol BibTex
2005-04-05 R-HSA-162742 (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI BibTex
2005-03-17 R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) BibTex
2005-02-14 R-HSA-159005 urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR BibTex
2005-02-14 R-HSA-159001 urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR BibTex
2005-02-14 R-HSA-158942 urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR BibTex
2005-02-14 R-HSA-158925 plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) BibTex
2005-02-14 R-HSA-158982 plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) BibTex
2005-02-14 R-HSA-158959 urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR BibTex
2005-02-14 R-HSA-158941 plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein BibTex
2005-02-11 R-HSA-158893 alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin BibTex
2005-02-09 R-HSA-158800 fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 BibTex
2005-02-09 R-HSA-158795 fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 BibTex
2005-02-09 R-HSA-158766 fibrin multimer, crosslinked -> fibrin digestion products (plasmin) BibTex
2005-02-09 R-HSA-158750 crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin BibTex
2005-02-09 R-HSA-158747 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) BibTex
2005-02-09 R-HSA-158781 crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) BibTex
2005-02-09 R-HSA-158784 crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen BibTex
2005-02-06 R-HSA-158722 histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen BibTex
2005-02-06 R-HSA-158721 histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen BibTex
2005-01-20 R-HSA-158399 kallikrein binds SERPING1 BibTex
2005-01-20 R-HSA-158357 factor XIIa binds SERPING1 BibTex
2005-01-20 R-HSA-158340 kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin BibTex
2005-01-20 R-HSA-158333 factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) BibTex
2005-01-20 R-HSA-158300 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) BibTex
2005-01-20 R-HSA-158313 factor XII -> factor XIIa BibTex
2005-01-20 R-HSA-158311 kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin BibTex
2005-01-20 R-HSA-158251 prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer BibTex
2005-01-20 R-HSA-158218 prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer BibTex
2005-01-20 R-HSA-158354 kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer BibTex
2005-01-20 R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) BibTex
2005-01-20 R-HSA-158145 factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex BibTex
2005-01-20 R-HSA-158118 factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer BibTex
2005-01-20 R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer BibTex
2005-01-20 R-HSA-158164 factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) BibTex
2005-01-20 R-HSA-158278 factor VIIIa + factor IXa -> factor VIIIa:factor IXa BibTex
2004-09-21 R-HSA-71660 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O BibTex
2004-09-21 R-HSA-71670 PKM dephosphorylates PEP to PYR BibTex
2004-08-26 R-HSA-141026 Activated protein C cleaves factor Va to factor Vi intermediate form BibTex
2004-08-26 R-HSA-141046 activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin BibTex
2004-08-24 R-HSA-140851 fibrin multimer -> fibrin multimer, crosslinked + NH4+ BibTex
2004-08-24 R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides BibTex
2004-08-24 R-HSA-140847 factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain BibTex
2004-08-24 R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B BibTex
2004-08-24 R-HSA-140842 n fibrin monomers -> fibrin multimer BibTex
2004-08-24 R-HSA-140872 thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators BibTex
2004-08-24 R-HSA-140791 activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin BibTex
2004-08-24 R-HSA-140870 thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin BibTex
2004-08-24 R-HSA-140806 SERPINC1 binds SERPINC1 activators BibTex
2004-08-24 R-HSA-140825 TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa BibTex
2004-08-24 R-HSA-140823 factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) BibTex
2004-08-24 R-HSA-140686 factor Va + factor Xa -> Va:Xa complex (prothrombinase) BibTex
2004-08-24 R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) BibTex
2004-08-24 R-HSA-140696 factor V -> factor Va + factor V activation peptide BibTex
2004-08-24 R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) BibTex
2004-08-24 R-HSA-140748 tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex BibTex
2004-08-24 R-HSA-140736 factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) BibTex
2004-08-24 R-HSA-140769 factor VII -> factor VIIa BibTex
2004-08-24 R-HSA-140777 factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) BibTex
2004-08-24 R-HSA-140783 tissue factor (TF) + factor VII (F7) -> TF:F7 complex BibTex
2004-08-24 R-HSA-140761 sequestered tissue factor -> tissue factor BibTex
2004-06-23 R-HSA-8981553 GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol BibTex
2004-06-23 R-HSA-8981564 GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol BibTex
2004-06-23 R-HSA-8981574 GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol BibTex
2004-06-23 R-HSA-8981570 GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol BibTex
2004-03-17 R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ BibTex
2004-02-23 R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate BibTex
2004-02-23 R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] BibTex
2004-02-19 R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] BibTex
2004-02-13 R-HSA-73828 adenylosuccinate => adenosine 5'-monophosphate + fumarate BibTex
2004-02-13 R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi BibTex
2004-02-13 R-HSA-73806 AIR + CO2 => CAIR BibTex
2004-02-13 R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi BibTex
2004-02-12 R-HSA-73810 FGAM + ATP => AIR + ADP + Pi BibTex
2004-02-12 R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF BibTex
2004-02-12 R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi BibTex
2004-02-12 R-HSA-73800 SAICAR => AICAR + Fumarate BibTex
2004-02-12 R-HSA-73798 AICAR + 10-Formyl-THF => FAICAR + THF BibTex
2004-01-13 R-HSA-109530 Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 BibTex
2004-01-13 R-HSA-109527 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 BibTex
2004-01-13 R-HSA-109529 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 BibTex
2004-01-13 R-HSA-109538 Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 BibTex
2004-01-13 R-HSA-109539 Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 BibTex
2004-01-13 R-HSA-109536 Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 BibTex
2004-01-13 R-HSA-109534 Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 BibTex
2003-09-15 R-HSA-76031 2 H2O2 => O2 + 2 H2O BibTex
2003-06-25 R-HSA-70377 alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ BibTex
2003-06-24 R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] BibTex
2003-06-24 R-HSA-70906 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ BibTex
2003-06-24 R-HSA-70920 N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate BibTex
2003-06-24 R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propionate BibTex
2003-06-24 R-HSA-70899 histidine => urocanate + NH4+ BibTex
2003-06-24 R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH BibTex
2003-06-24 R-HSA-70667 1PYR-5COOH spontaneously hydrolyses to L-GluSS BibTex
2003-06-24 R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] BibTex
2003-06-24 R-HSA-70573 argininosuccinate <=> fumarate + arginine BibTex
2003-06-24 R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 BibTex
2003-06-24 R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ BibTex
2003-06-24 R-HSA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O BibTex
2003-06-24 R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr BibTex
2003-06-24 R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ BibTex
2003-06-24 R-HSA-517444 TAT aminates HPP BibTex
2003-06-24 R-HSA-71155 TAT deaminates tyrosine BibTex
2003-06-24 R-HSA-71163 HPD dioxygenates HPP BibTex
2003-06-24 R-HSA-71164 HGD dioxygenates homogentisate BibTex
2003-06-24 R-HSA-71173 GSTZ1 isomerizes 4-MAA BibTex
2003-06-24 R-HSA-71181 FAH cleaves 4FAA BibTex
2003-06-24 R-HSA-893593 phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine BibTex
2003-06-24 R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O BibTex
2003-06-24 R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ BibTex
2003-06-24 R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ BibTex
2003-06-24 R-HSA-70952 alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate BibTex
2003-06-24 R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu BibTex
2003-06-24 R-HSA-70634 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) BibTex
2003-06-24 R-HSA-70560 carbamoyl phosphate + ornithine => citrulline + orthophosphate BibTex
2003-06-24 R-HSA-70555 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] BibTex
2003-06-24 R-HSA-70542 glutamate + acetyl CoA => N-acetyl glutamate + CoA BibTex
2003-06-24 R-HSA-70577 ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA BibTex
2003-05-04 R-HSA-70609 glutamine + H2O => glutamate + NH4+ [GLS] BibTex
Reviewed Pathways (334/334)
Date Identifier Pathway Reference
2024-03-04 R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production BibTex
2024-03-04 R-HSA-9634597 GPER1 signaling BibTex
2024-03-04 R-HSA-1430728 Metabolism BibTex
2024-03-04 R-HSA-420092 Glucagon-type ligand receptors BibTex
2024-03-04 R-HSA-163615 PKA activation BibTex
2024-03-01 R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins BibTex
2024-02-19 R-HSA-428643 Organic anion transporters BibTex
2024-02-19 R-HSA-389661 Glyoxylate metabolism and glycine degradation BibTex
2024-02-08 R-HSA-389542 NADPH regeneration BibTex
2024-01-29 R-HSA-9634597 GPER1 signaling BibTex
2024-01-29 R-HSA-163615 PKA activation BibTex
2024-01-29 R-HSA-420092 Glucagon-type ligand receptors BibTex
2024-01-29 R-HSA-9660821 ADORA2B mediated anti-inflammatory cytokines production BibTex
2023-12-08 R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers BibTex
2023-10-27 R-HSA-1660662 Glycosphingolipid metabolism BibTex
2023-10-26 R-HSA-382551 Transport of small molecules BibTex
2023-10-24 R-HSA-428157 Sphingolipid metabolism BibTex
2023-10-24 R-HSA-9845576 Glycosphingolipid transport BibTex
2023-10-24 R-HSA-1660662 Glycosphingolipid metabolism BibTex
2023-10-24 R-HSA-9840309 Glycosphingolipid biosynthesis BibTex
2023-10-24 R-HSA-9845614 Sphingolipid catabolism BibTex
2023-10-24 R-HSA-1660661 Sphingolipid de novo biosynthesis BibTex
2023-10-13 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases BibTex
2023-08-22 R-HSA-196071 Metabolism of steroid hormones BibTex
2023-08-22 R-HSA-71387 Metabolism of carbohydrates BibTex
2023-08-22 R-HSA-9840310 Glycosphingolipid catabolism BibTex
2023-08-17 R-HSA-1660661 Sphingolipid de novo biosynthesis BibTex
2023-08-17 R-HSA-428157 Sphingolipid metabolism BibTex
2023-08-17 R-HSA-1660662 Glycosphingolipid metabolism BibTex
2023-08-17 R-HSA-9840309 Glycosphingolipid biosynthesis BibTex
2023-01-27 R-HSA-9824443 Parasitic Infection Pathways BibTex
2023-01-27 R-HSA-9824446 Viral Infection Pathways BibTex
2023-01-27 R-HSA-9824439 Bacterial Infection Pathways BibTex
2022-01-05 R-HSA-9758274 Regulation of NF-kappa B signaling BibTex
2021-12-13 R-HSA-9759785 Diseases of propionyl-CoA catabolism BibTex
2021-09-23 R-HSA-9748784 Drug ADME BibTex
2021-08-18 R-HSA-9734009 Defective Intrinsic Pathway for Apoptosis BibTex
2021-02-25 R-HSA-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 BibTex
2021-02-17 R-HSA-9710421 Defective pyroptosis BibTex
2021-02-17 R-HSA-5620971 Pyroptosis BibTex
2021-01-27 R-HSA-9692916 SARS-CoV-1 activates/modulates innate immune responses BibTex
2021-01-26 R-HSA-9709957 Sensory Perception BibTex
2021-01-26 R-HSA-9692914 SARS-CoV-1-host interactions BibTex
2021-01-26 R-HSA-9735871 SARS-CoV-1 targets host intracellular signalling and regulatory pathways BibTex
2021-01-26 R-HSA-9735869 SARS-CoV-1 modulates host translation machinery BibTex
2021-01-26 R-HSA-9692912 SARS-CoV-1 targets PDZ proteins in cell-cell junction BibTex
2021-01-26 R-HSA-9692913 SARS-CoV-1-mediated effects on programmed cell death BibTex
2020-11-11 R-HSA-9675135 Diseases of DNA repair BibTex
2020-11-11 R-HSA-9675136 Diseases of DNA Double-Strand Break Repair BibTex
2020-08-18 R-HSA-9675151 Disorders of Developmental Biology BibTex
2020-08-14 R-HSA-9697154 Disorders of Nervous System Development BibTex
2020-06-26 R-HSA-9693928 Defective RIPK1-mediated regulated necrosis BibTex
2020-06-26 R-HSA-9686347 Microbial modulation of RIPK1-mediated regulated necrosis BibTex
2020-02-24 R-HSA-9675132 Diseases of cellular response to stress BibTex
2020-02-24 R-HSA-9675151 Disorders of Developmental Biology BibTex
2020-02-24 R-HSA-9675135 Diseases of DNA repair BibTex
2020-02-24 R-HSA-9675143 Diseases of the neuronal system BibTex
2020-01-09 R-HSA-9671793 Diseases of hemostasis BibTex
2020-01-09 R-HSA-9651496 Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) BibTex
2020-01-09 R-HSA-9672383 Defective factor IX causes thrombophilia BibTex
2020-01-09 R-HSA-9672387 Defective F8 accelerates dissociation of the A2 domain BibTex
2020-01-09 R-HSA-9674519 Defective F8 sulfation at Y1699 BibTex
2020-01-09 R-HSA-9672391 Defective F8 cleavage by thrombin BibTex
2020-01-09 R-HSA-9672395 Defective F8 binding to the cell membrane BibTex
2020-01-09 R-HSA-9672393 Defective F8 binding to von Willebrand factor BibTex
2020-01-09 R-HSA-9672397 Defective F8 secretion BibTex
2020-01-09 R-HSA-9672396 Defective cofactor function of FVIIIa variant BibTex
2020-01-09 R-HSA-9662001 Defective factor VIII causes hemophilia A BibTex
2020-01-09 R-HSA-9673218 Defective F9 secretion BibTex
2020-01-09 R-HSA-9673202 Defective F9 variant does not activate FX BibTex
2020-01-09 R-HSA-9673221 Defective F9 activation BibTex
2020-01-09 R-HSA-9673240 Defective gamma-carboxylation of F9 BibTex
2020-01-09 R-HSA-9668250 Defective factor IX causes hemophilia B BibTex
2020-01-09 R-HSA-9657689 Defective SERPING1 causes hereditary angioedema BibTex
2020-01-09 R-HSA-9657688 Defective factor XII causes hereditary angioedema BibTex
2018-12-29 R-HSA-9024446 NR1H2 and NR1H3-mediated signaling BibTex
2018-12-29 R-HSA-9029558 NR1H2 & NR1H3 regulate gene expression linked to lipogenesis BibTex
2018-12-29 R-HSA-9632974 NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis BibTex
2018-12-29 R-HSA-9031525 NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake BibTex
2018-12-29 R-HSA-9623433 NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis BibTex
2018-12-29 R-HSA-9031528 NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose BibTex
2018-12-29 R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux BibTex
2018-12-22 R-HSA-434313 Intracellular metabolism of fatty acids regulates insulin secretion BibTex
2017-12-02 R-HSA-8983711 OAS antiviral response BibTex
2017-06-22 R-HSA-9006934 Signaling by Receptor Tyrosine Kinases BibTex
2017-06-22 R-HSA-9006931 Signaling by Nuclear Receptors BibTex
2017-06-22 R-HSA-9006936 Signaling by TGFB family members BibTex
2017-06-22 R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases BibTex
2017-06-22 R-HSA-9006925 Intracellular signaling by second messengers BibTex
2017-02-10 R-HSA-8963743 Digestion and absorption BibTex
2016-10-11 R-HSA-8937144 Aryl hydrocarbon receptor signalling BibTex
2016-10-11 R-HSA-8942233 Intestinal infectious diseases BibTex
2016-08-18 R-HSA-8863678 Neurodegenerative Diseases BibTex
2016-08-12 R-HSA-8935690 Digestion BibTex
2016-07-15 R-HSA-8877627 Vitamin E BibTex
2016-04-20 R-HSA-8963889 Assembly of active LPL and LIPC lipase complexes BibTex
2016-04-05 R-HSA-8964572 Lipid particle organization BibTex
2016-04-05 R-HSA-8866376 Reelin signalling pathway BibTex
2016-04-05 R-HSA-8866427 VLDLR internalisation and degradation BibTex
2016-04-05 R-HSA-8964046 VLDL clearance BibTex
2016-04-05 R-HSA-8866423 VLDL assembly BibTex
2016-01-26 R-HSA-8853383 Lysosomal oligosaccharide catabolism BibTex
2016-01-11 R-HSA-8852405 Signaling by MST1 BibTex
2016-01-11 R-HSA-8849175 Threonine catabolism BibTex
2016-01-11 R-HSA-6798163 Choline catabolism BibTex
2015-09-14 R-HSA-6787639 GDP-fucose biosynthesis BibTex
2015-09-12 R-HSA-5686938 Regulation of TLR by endogenous ligand BibTex
2015-08-17 R-HSA-5687613 Diseases associated with surfactant metabolism BibTex
2015-08-17 R-HSA-5688890 Defective CSF2RA causes SMDP4 BibTex
2015-08-17 R-HSA-5687868 Defective SFTPA2 causes IPF BibTex
2015-08-17 R-HSA-5688399 Defective ABCA3 causes SMDP3 BibTex
2015-08-17 R-HSA-5688031 Defective pro-SFTPB causes SMDP1 and RDS BibTex
2015-08-17 R-HSA-5687583 Defective SLC34A2 causes PALM BibTex
2015-08-17 R-HSA-5688849 Defective CSF2RB causes SMDP5 BibTex
2015-08-17 R-HSA-5688354 Defective pro-SFTPC causes SMDP2 and RDS BibTex
2015-08-17 R-HSA-5683826 Surfactant metabolism BibTex
2015-06-26 R-HSA-6783984 Glycine degradation BibTex
2015-02-22 R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs BibTex
2015-02-11 R-HSA-5223345 Miscellaneous transport and binding events BibTex
2015-02-11 R-HSA-8981607 Intracellular oxygen transport BibTex
2014-09-06 R-HSA-5260271 Diseases of Immune System BibTex
2014-09-06 R-HSA-5602358 Diseases associated with the TLR signaling cascade BibTex
2014-09-06 R-HSA-5602410 TLR3 deficiency - HSE BibTex
2014-09-06 R-HSA-5602571 TRAF3 deficiency - HSE BibTex
2014-09-06 R-HSA-5602680 MyD88 deficiency (TLR5) BibTex
2014-09-06 R-HSA-5602415 UNC93B1 deficiency - HSE BibTex
2014-09-06 R-HSA-5602636 IKBKB deficiency causes SCID BibTex
2014-09-06 R-HSA-5603037 IRAK4 deficiency (TLR5) BibTex
2014-09-06 R-HSA-5602498 MyD88 deficiency (TLR2/4) BibTex
2014-09-06 R-HSA-5603027 IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) BibTex
2014-09-06 R-HSA-5603041 IRAK4 deficiency (TLR2/4) BibTex
2014-09-06 R-HSA-5602566 TICAM1 deficiency - HSE BibTex
2014-09-06 R-HSA-5603029 IkBA variant leads to EDA-ID BibTex
2014-05-22 R-HSA-5423646 Aflatoxin activation and detoxification BibTex
2014-02-07 R-HSA-5173105 O-linked glycosylation BibTex
2014-02-07 R-HSA-5173214 O-glycosylation of TSR domain-containing proteins BibTex
2013-04-15 R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism BibTex
2013-02-11 R-HSA-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production BibTex
2013-02-11 R-HSA-3249367 STAT6-mediated induction of chemokines BibTex
2013-02-11 R-HSA-3270619 IRF3-mediated induction of type I IFN BibTex
2013-02-11 R-HSA-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production BibTex
2013-02-11 R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA BibTex
2013-02-11 R-HSA-3248023 Regulation by TREX1 BibTex
2012-11-07 R-GGA-2132285 Complement Cascade BibTex
2012-11-07 R-GGA-2132287 Creation of alternative pathway C3 convertase BibTex
2012-11-07 R-GGA-2132293 Formation of fluid-phase convertase C3 BibTex
2012-11-07 R-GGA-2173345 Anaphylatoxins initiate inflammatory responses BibTex
2012-11-07 R-GGA-2132270 Lectin-mediated initiation of complement cascade BibTex
2012-11-07 R-GGA-2132286 Classical antibody-mediated complement activation BibTex
2012-11-07 R-GGA-2132263 Creation of classical C3 convertase BibTex
2012-11-07 R-GGA-2132281 Regulation of complement cascades BibTex
2012-11-07 R-GGA-2132267 Formation of membrane attack complex (MAC) BibTex
2012-11-07 R-GGA-2132273 Formation of membrane-bound convertase C3 BibTex
2012-11-05 R-GGA-2422406 Innate Immune System BibTex
2012-07-18 R-HSA-1834941 STING mediated induction of host immune responses BibTex
2012-05-20 R-HSA-8953897 Cellular responses to stimuli BibTex
2012-05-20 R-HSA-2262752 Cellular responses to stress BibTex
2012-05-20 R-HSA-1483257 Phospholipid metabolism BibTex
2012-05-14 R-HSA-1663150 The activation of arylsulfatases BibTex
2012-04-23 R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK BibTex
2012-04-23 R-HSA-2179392 EGFR Transactivation by Gastrin BibTex
2012-03-28 R-HSA-1630316 Glycosaminoglycan metabolism BibTex
2012-03-28 R-HSA-2142845 Hyaluronan metabolism BibTex
2012-03-28 R-HSA-2160916 Hyaluronan uptake and degradation BibTex
2012-03-28 R-HSA-2142850 Hyaluronan biosynthesis and export BibTex
2012-03-28 R-HSA-1793185 Chondroitin sulfate/dermatan sulfate metabolism BibTex
2012-03-28 R-HSA-2024101 CS/DS degradation BibTex
2012-03-28 R-HSA-2022870 Chondroitin sulfate biosynthesis BibTex
2012-03-28 R-HSA-2022923 Dermatan sulfate biosynthesis BibTex
2012-03-28 R-HSA-1638091 Heparan sulfate/heparin (HS-GAG) metabolism BibTex
2012-03-28 R-HSA-2024096 HS-GAG degradation BibTex
2012-03-28 R-HSA-2022857 Keratan sulfate degradation BibTex
2012-03-28 R-HSA-2022854 Keratan sulfate biosynthesis BibTex
2012-03-28 R-HSA-1638074 Keratan sulfate/keratin metabolism BibTex
2012-03-28 R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis BibTex
2012-03-28 R-HSA-2022928 HS-GAG biosynthesis BibTex
2012-02-28 R-HSA-1474244 Extracellular matrix organization BibTex
2012-02-28 R-HSA-1474228 Degradation of the extracellular matrix BibTex
2011-12-08 R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA BibTex
2011-12-08 R-HSA-1606322 ZBP1(DAI) mediated induction of type I IFNs BibTex
2011-12-08 R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 BibTex
2011-12-08 R-HSA-1606341 IRF3 mediated activation of type 1 IFN BibTex
2011-11-02 R-HSA-1268020 Mitochondrial protein import BibTex
2011-10-26 R-HSA-977347 Serine biosynthesis BibTex
2011-10-13 R-HSA-1614635 Sulfur amino acid metabolism BibTex
2011-10-13 R-HSA-1614558 Degradation of cysteine and homocysteine BibTex
2011-10-13 R-HSA-1614517 Sulfide oxidation to sulfate BibTex
2011-10-13 R-HSA-1614603 Cysteine formation from homocysteine BibTex
2011-08-23 R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation BibTex
2011-08-23 R-HSA-382556 ABC-family proteins mediated transport BibTex
2011-08-23 R-HSA-1369007 Mitochondrial ABC transporters BibTex
2011-08-23 R-HSA-1369062 ABC transporters in lipid homeostasis BibTex
2011-05-23 R-HSA-156590 Glutathione conjugation BibTex
2011-05-23 R-HSA-174403 Glutathione synthesis and recycling BibTex
2011-05-23 R-HSA-1237112 Methionine salvage pathway BibTex
2010-12-06 R-GGA-451529 TLR15 cascade BibTex
2010-12-06 R-GGA-451531 TLR21 cascade BibTex
2010-12-06 R-GGA-451498 TLR7 cascade BibTex
2010-12-06 R-GGA-451477 MyD88-dependent cascade initiated on endosome membrane BibTex
2010-12-06 R-GGA-573298 NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation BibTex
2010-12-06 R-GGA-451534 TLR5 cascade BibTex
2010-12-06 R-GGA-977240 MyD88 cascade initiated on plasma membrane BibTex
2010-11-09 R-HSA-975634 Retinoid metabolism and transport BibTex
2010-11-08 R-HSA-964975 Vitamin B6 activation to pyridoxal phosphate BibTex
2010-11-05 R-HSA-947581 Molybdenum cofactor biosynthesis BibTex
2010-11-05 R-HSA-917937 Iron uptake and transport BibTex
2010-11-05 R-HSA-917977 Transferrin endocytosis and recycling BibTex
2010-10-16 R-GGA-517856 TLR2 subfamily cascade BibTex
2010-10-16 R-GGA-433794 TLR4 cascade BibTex
2010-10-16 R-GGA-451514 MyD88:TIRAP-dependent cascade initiated on plasma membrane BibTex
2010-10-16 R-GGA-433822 NFkB and MAPK activation mediated by TRAF6 BibTex
2010-10-15 R-GGA-451478 ERK activation BibTex
2010-05-23 R-GGA-437987 Toll-like receptors (TLR) cascades BibTex
2010-05-23 R-GGA-434048 TLR3 cascade BibTex
2010-05-23 R-GGA-433835 IKK related kinases bound to dsRNA:TLR3:TICAM1 activate IRF3 BibTex
2010-05-23 R-GGA-434136 Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 BibTex
2010-05-23 R-GGA-433819 Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK BibTex
2010-05-23 R-GGA-433871 TRAF6 mediated induction of proinflammatory cytokines BibTex
2010-05-23 R-GGA-434131 NFkB activation mediated by RIP1 complexed with activated TLR3 BibTex
2010-05-23 R-GGA-451524 MAPK activation in TLR cascade BibTex
2010-05-23 R-GGA-437980 Activated TAK1 mediates p38 MAP kinase phosphorylation BibTex
2010-05-23 R-GGA-437986 Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation BibTex
2010-05-23 R-GGA-434001 TAK1 activates NFkB by phosphorylation and activation of IKKs complex BibTex
2009-12-12 R-HSA-500792 GPCR ligand binding BibTex
2009-12-12 R-HSA-444209 Free fatty acid receptors BibTex
2009-12-12 R-HSA-444473 Formyl peptide receptors bind formyl peptides and many other ligands BibTex
2009-12-12 R-HSA-444821 Relaxin receptors BibTex
2009-09-07 R-HSA-422356 Regulation of insulin secretion BibTex
2009-08-22 R-GGA-433584 Sphingolipid metabolism BibTex
2009-06-02 R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion BibTex
2009-05-29 R-HSA-373080 Class B/2 (Secretin family receptors) BibTex
2009-05-29 R-HSA-420092 Glucagon-type ligand receptors BibTex
2009-05-29 R-HSA-419812 Calcitonin-like ligand receptors BibTex
2009-05-29 R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) BibTex
2009-05-29 R-HSA-419771 Opsins BibTex
2009-05-29 R-HSA-391903 Eicosanoid ligand-binding receptors BibTex
2009-05-29 R-HSA-391906 Leukotriene receptors BibTex
2009-05-29 R-HSA-391908 Prostanoid ligand receptors BibTex
2009-05-29 R-HSA-417957 P2Y receptors BibTex
2009-05-29 R-HSA-417973 Adenosine P1 receptors BibTex
2009-05-29 R-HSA-418038 Nucleotide-like (purinergic) receptors BibTex
2009-05-29 R-HSA-419408 Lysosphingolipid and LPA receptors BibTex
2009-05-27 R-HSA-400253 Circadian Clock BibTex
2009-05-27 R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression BibTex
2009-05-27 R-HSA-381340 Transcriptional regulation of white adipocyte differentiation BibTex
2009-05-23 R-GGA-421984 Heme synthesis BibTex
2009-05-16 R-GGA-421223 De novo synthesis of GMP BibTex
2009-05-16 R-GGA-421203 De novo synthesis of AMP BibTex
2009-05-15 R-GGA-421178 Urate synthesis BibTex
2009-04-29 R-GGA-419140 De novo synthesis of IMP BibTex
2009-03-02 R-HSA-375280 Amine ligand-binding receptors BibTex
2009-03-02 R-HSA-390666 Serotonin receptors BibTex
2009-03-02 R-HSA-390650 Histamine receptors BibTex
2009-03-02 R-HSA-390651 Dopamine receptors BibTex
2009-03-02 R-HSA-390696 Adrenoceptors BibTex
2009-03-02 R-HSA-389397 Orexin and neuropeptides FF and QRFP bind to their respective receptors BibTex
2009-03-02 R-HSA-380095 Tachykinin receptors bind tachykinins BibTex
2009-03-02 R-HSA-388479 Vasopressin-like receptors BibTex
2009-03-02 R-HSA-375281 Hormone ligand-binding receptors BibTex
2009-03-02 R-HSA-390648 Muscarinic acetylcholine receptors BibTex
2008-12-02 R-HSA-264876 Insulin processing BibTex
2008-12-02 R-HSA-381119 Unfolded Protein Response (UPR) BibTex
2008-12-02 R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones BibTex
2008-12-02 R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes BibTex
2008-12-02 R-HSA-381070 IRE1alpha activates chaperones BibTex
2008-12-02 R-HSA-381038 XBP1(S) activates chaperone genes BibTex
2008-12-02 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) BibTex
2008-12-02 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane BibTex
2008-12-02 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress BibTex
2008-12-02 R-HSA-381042 PERK regulates gene expression BibTex
2008-11-29 R-HSA-209952 Peptide hormone biosynthesis BibTex
2008-11-29 R-HSA-209822 Glycoprotein hormones BibTex
2008-09-10 R-GGA-187630 Arginine metabolism BibTex
2008-06-12 R-HSA-350562 Regulation of ornithine decarboxylase (ODC) BibTex
2008-06-12 R-HSA-351202 Metabolism of polyamines BibTex
2008-06-12 R-HSA-351200 Interconversion of polyamines BibTex
2008-06-12 R-HSA-351143 Agmatine biosynthesis BibTex
2008-05-28 R-HSA-211859 Biological oxidations BibTex
2008-05-28 R-HSA-211945 Phase I - Functionalization of compounds BibTex
2008-05-28 R-HSA-211897 Cytochrome P450 - arranged by substrate type BibTex
2008-05-28 R-HSA-211916 Vitamins BibTex
2008-05-28 R-HSA-211981 Xenobiotics BibTex
2008-05-28 R-HSA-211999 CYP2E1 reactions BibTex
2008-05-28 R-HSA-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 BibTex
2008-05-28 R-HSA-211935 Fatty acids BibTex
2008-05-28 R-HSA-211976 Endogenous sterols BibTex
2008-05-28 R-HSA-211994 Sterols are 12-hydroxylated by CYP8B1 BibTex
2008-05-28 R-HSA-211979 Eicosanoids BibTex
2008-05-28 R-HSA-211958 Miscellaneous substrates BibTex
2008-05-28 R-HSA-140180 COX reactions BibTex
2008-05-28 R-HSA-217271 FMO oxidises nucleophiles BibTex
2008-05-28 R-HSA-140179 Amine Oxidase reactions BibTex
2008-05-28 R-HSA-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB BibTex
2008-05-28 R-HSA-141334 PAOs oxidise polyamines to amines BibTex
2008-05-28 R-HSA-196791 Vitamin D (calciferol) metabolism BibTex
2008-05-28 R-HSA-209905 Catecholamine biosynthesis BibTex
2008-05-28 R-HSA-350864 Regulation of thyroid hormone activity BibTex
2008-05-28 R-HSA-209968 Thyroxine biosynthesis BibTex
2008-05-28 R-HSA-209931 Serotonin and melatonin biosynthesis BibTex
2008-05-28 R-HSA-209776 Metabolism of amine-derived hormones BibTex
2008-01-12 R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex BibTex
2007-07-31 R-HSA-200425 Carnitine metabolism BibTex
2007-07-10 R-HSA-196783 Coenzyme A biosynthesis BibTex
2007-04-30 R-HSA-194068 Bile acid and bile salt metabolism BibTex
2007-04-30 R-HSA-192105 Synthesis of bile acids and bile salts BibTex
2007-04-30 R-HSA-193807 Synthesis of bile acids and bile salts via 27-hydroxycholesterol BibTex
2007-04-30 R-HSA-193775 Synthesis of bile acids and bile salts via 24-hydroxycholesterol BibTex
2007-04-30 R-HSA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol BibTex
2007-04-30 R-HSA-159418 Recycling of bile acids and salts BibTex
2007-04-21 R-HSA-196071 Metabolism of steroid hormones BibTex
2007-04-21 R-HSA-196108 Pregnenolone biosynthesis BibTex
2007-04-21 R-HSA-193993 Mineralocorticoid biosynthesis BibTex
2007-04-21 R-HSA-193144 Estrogen biosynthesis BibTex
2007-04-21 R-HSA-193048 Androgen biosynthesis BibTex
2007-04-21 R-HSA-194002 Glucocorticoid biosynthesis BibTex
2007-02-03 R-HSA-8978868 Fatty acid metabolism BibTex
2007-02-03 R-HSA-8979227 Triglyceride metabolism BibTex
2007-02-03 R-HSA-163560 Triglyceride catabolism BibTex
2007-02-03 R-HSA-75109 Triglyceride biosynthesis BibTex
2007-01-22 R-HSA-191273 Cholesterol biosynthesis BibTex
2006-11-03 R-HSA-9840310 Glycosphingolipid catabolism BibTex
2006-10-31 R-HSA-168898 Toll-like Receptor Cascades BibTex
2006-07-04 R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade BibTex
2006-07-04 R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade BibTex
2006-07-04 R-HSA-174577 Activation of C3 and C5 BibTex
2006-07-04 R-HSA-166662 Lectin pathway of complement activation BibTex
2006-07-04 R-HSA-173623 Classical antibody-mediated complement activation BibTex
2006-07-04 R-HSA-166786 Creation of C4 and C2 activators BibTex
2006-07-04 R-HSA-173736 Alternative complement activation BibTex
2006-07-04 R-HSA-166663 Initial triggering of complement BibTex
2006-07-04 R-HSA-166665 Terminal pathway of complement BibTex
2006-07-04 R-HSA-166658 Complement cascade BibTex
2006-07-04 R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade BibTex
2006-04-19 R-HSA-168256 Immune System BibTex
Reviewed Reactions (2,010/2,010)
Date Identifier Reaction Reference
2024-03-04 R-HSA-5690886 ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs BibTex
2024-03-04 R-HSA-5690873 ACO1 binds 4Fe-4S BibTex
2024-03-04 R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 BibTex
2024-03-04 R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK BibTex
2024-02-08 R-HSA-71037 alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ BibTex
2024-02-08 R-HSA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT BibTex
2024-02-08 R-HSA-70713 BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV BibTex
2024-01-29 R-HSA-111925 cAMP induces dissociation of inactive PKA tetramers BibTex
2024-01-29 R-HSA-163617 G alpha (s) activates adenylate cyclase BibTex
2024-01-29 R-HSA-422320 Heterotrimeric G(s) complex dissociates BibTex
2024-01-29 R-HSA-400023 Gq alpha activates Phospholipase C beta BibTex
2024-01-29 R-HSA-163617 G alpha (s) activates adenylate cyclase BibTex
2024-01-29 R-HSA-111925 cAMP induces dissociation of inactive PKA tetramers BibTex
2024-01-29 R-HSA-381612 GLP1R binds GLP1 BibTex
2024-01-29 R-HSA-163625 Glucagon binds to Glucagon receptor BibTex
2024-01-29 R-HSA-400027 Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma BibTex
2023-12-13 R-HSA-71181 FAH cleaves 4FAA BibTex
2023-12-13 R-HSA-71164 HGD dioxygenates homogentisate BibTex
2023-12-13 R-HSA-71163 HPD dioxygenates HPP BibTex
2023-10-24 R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin BibTex
2023-10-24 R-HSA-9850731 Vesicles transport GSL from Golgi to plasma membrane BibTex
2023-10-24 R-HSA-9845055 PLEKHA8 catalyzes transport of GlcCer to plasma membrane BibTex
2023-10-24 R-HSA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane BibTex
2023-10-24 R-HSA-9844955 CLN3 transports GalCer to plasma membrane BibTex
2023-10-24 R-HSA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane BibTex
2023-10-24 R-HSA-5340320 GLTP transports GSL from plasma membrane to ER membrane BibTex
2023-10-24 R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer BibTex
2023-10-24 R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b BibTex
2023-10-24 R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine BibTex
2023-10-24 R-HSA-428123 KDSR reduces 3-ketosphingoid BibTex
2023-10-24 R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid BibTex
2023-10-24 R-HSA-428260 DEGS2 oxygenates dihydroceramide BibTex
2023-10-24 R-HSA-428262 ACER3 hydrolyzes phytoceramide BibTex
2023-10-24 R-HSA-428259 DEGS1 dehydrogenates dihydroceramide BibTex
2023-10-24 R-HSA-9695949 SPHK2 phosphorylates sphingoid BibTex
2023-10-24 R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate BibTex
2023-10-24 R-HSA-428273 SPHK1 phosphorylates sphingoid BibTex
2023-10-24 R-HSA-428681 PXLP-SGPL1 cleaves sphingoid-1-phosphates BibTex
2023-10-24 R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM BibTex
2023-10-24 R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM BibTex
2023-10-24 R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM BibTex
2023-10-24 R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) BibTex
2023-10-24 R-HSA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region BibTex
2023-10-24 R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region BibTex
2023-10-24 R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate BibTex
2023-10-24 R-HSA-429694 CERT1-2 complex dissociates BibTex
2023-10-24 R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 BibTex
2023-10-24 R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 BibTex
2023-10-24 R-HSA-429732 Multiphospho-CERT1-2 binds PPM1L, VAPA/B BibTex
2023-10-24 R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 BibTex
2023-10-24 R-HSA-429699 CERT1-2 complex binds ceramide BibTex
2023-10-24 R-HSA-429683 CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus BibTex
2023-10-24 R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) BibTex
2023-10-24 R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates BibTex
2023-10-24 R-HSA-429798 SGMS1 transfers phosphocholine onto ceramide BibTex
2023-10-24 R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER BibTex
2023-10-24 R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids BibTex
2023-10-24 R-HSA-429786 SGMS2 transfers phosphocholine onto ceramide BibTex
2023-10-24 R-HSA-9695917 SPHK2 binds SPHK2 inhibitors BibTex
2023-10-24 R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases BibTex
2023-10-24 R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide BibTex
2023-10-24 R-HSA-1638104 UGCG transfers glucose to ceramide BibTex
2023-10-24 R-HSA-1638845 CERK phosphorylates CERA to form C1P BibTex
2023-10-24 R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer BibTex
2023-10-24 R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides BibTex
2023-10-24 R-HSA-9846477 A4GALT transfers galactose to LacCer BibTex
2023-10-24 R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer BibTex
2023-10-24 R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA BibTex
2023-10-24 R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides BibTex
2023-10-24 R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides BibTex
2023-10-24 R-HSA-9845516 B3GALT4 transfers Gal to gangliosides BibTex
2023-10-24 R-HSA-9846332 FUT1,2 transfer fucose to gangliosides BibTex
2023-10-24 R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer BibTex
2023-10-24 R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides BibTex
2023-08-22 R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 BibTex
2023-08-22 R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands BibTex
2023-08-18 R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation BibTex
2023-08-18 R-HSA-217255 FMO1:FAD N-oxidises TAM BibTex
2023-08-18 R-HSA-8937419 CBR3 reduces DOX to DOXOL BibTex
2023-08-18 R-HSA-9842115 PSAP(195-273) dimer binds PE BibTex
2023-08-17 R-HSA-1606602 ASAH1 hydrolyzes ceramide BibTex
2023-08-17 R-HSA-1605797 SMPD1 hydrolyzes SPHM BibTex
2023-08-17 R-HSA-1605717 GM2A binds and mobilizes ligands BibTex
2023-08-17 R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide BibTex
2023-08-17 R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) BibTex
2023-08-17 R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) BibTex
2023-08-17 R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine BibTex
2023-08-17 R-HSA-1606564 GALC hydrolyzes GalCer BibTex
2023-08-17 R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer BibTex
2023-08-17 R-HSA-9840949 ARSA removes sulfate from SM3 BibTex
2023-08-17 R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 BibTex
2023-08-17 R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 BibTex
2023-08-17 R-HSA-9840579 GM1 localizes to ILV membrane BibTex
2023-08-17 R-HSA-9840581 GM1 localizes to endosome membrane BibTex
2023-08-17 R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE BibTex
2023-08-17 R-HSA-9840488 PSAP(195-273) forms a dimer BibTex
2023-08-17 R-HSA-9840334 PSAP gets cleaved BibTex
2023-06-24 R-HSA-6786190 CMBL hydrolyses OM to OLMS BibTex
2022-08-05 R-HSA-9793988 LUBAC ubiquitinates CFLAR at K351, K353 BibTex
2022-08-05 R-HSA-9794008 LUBAC binds CFLAR BibTex
2022-08-05 R-HSA-9793680 OPTN binds polyUb-RIPK1 within the TNFR1 complex BibTex
2022-08-05 R-HSA-9793679 LUBAC ubiquitinates RIPK1 at K627 BibTex
2022-07-05 R-HSA-9793485 PRKN polyubiquitinates RIPK3 BibTex
2022-07-05 R-HSA-9793472 RIPK3 binds p-S9-PRKN BibTex
2022-07-05 R-HSA-9793444 ITCH polyubiquitinates MLKL at K50 BibTex
2022-07-05 R-HSA-9793451 MLKL binds ITCH BibTex
2022-01-05 R-HSA-9750942 USP14 deubiquitinates NLRC5 BibTex
2022-01-05 R-HSA-9750226 NLRC5 binds IKBKB and CHUK BibTex
2022-01-05 R-HSA-9750946 TRAF2,6 ubiquitinates NLRC5 BibTex
2022-01-05 R-HSA-9749464 TP53 binds the IKBIP gene promoter BibTex
2022-01-05 R-HSA-9749487 TP53 stimulates IKBIP gene expression BibTex
2022-01-05 R-HSA-9749494 IKBIP binds IKBKB and CHUK BibTex
2022-01-05 R-HSA-9761344 USP18 binds IKBKG within IKK complex BibTex
2022-01-05 R-HSA-9749505 LRRC14 binds IKBKB and CHUK BibTex
2022-01-05 R-HSA-9757954 N4BP1 binds IKBKG BibTex
2022-01-05 R-HSA-9749471 NLRX1 binds CHUK:IKBKB:IKBKG BibTex
2022-01-05 R-HSA-9757951 CASP8 cleaves N4BP1 at D424, D490 BibTex
2022-01-05 R-HSA-9758604 Ubiquitination of IKBKG by TRAF6 BibTex
2021-07-23 R-HSA-9737780 MTTP binds lomitapide BibTex
2021-06-21 R-HSA-9733960 Bile salts and acids dissociate from ALB BibTex
2021-06-21 R-HSA-9733545 Bile salts and acids bind ALB BibTex
2021-06-21 R-HSA-9733964 SLC51A:SLC51B transports bile salts from cytosol to extracellular region BibTex
2021-06-21 R-HSA-9733969 Bile salts dissociate from FABP6 BibTex
2021-06-21 R-HSA-9733973 Bile salts bind FABP6 BibTex
2021-02-17 R-HSA-9710490 The GSDME gene promoter is hypermethylated BibTex
2021-02-17 R-HSA-9710480 Decitabine triphosphate incorporates into DNA BibTex
2021-02-17 R-HSA-9710468 GSDME variant does not bind PIPs BibTex
2021-02-17 R-HSA-9686088 CASP3 cleaves GSDMD BibTex
2021-02-17 R-HSA-9647619 GSDMD forms ring?shaped oligomers BibTex
2021-02-17 R-HSA-9693324 Disulfiram covalently modifies Cys191 in GSDMD BibTex
2021-02-17 R-HSA-449058 Interleukin-1 family are secreted BibTex
2021-02-17 R-HSA-9710254 GSDME oligomerizes BibTex
2021-02-17 R-HSA-9647660 GSDME (1-270) binds PIPs BibTex
2021-02-17 R-HSA-9647643 GSDMD (1-275) binds bacterial cardiolipin BibTex
2021-02-17 R-HSA-9647645 GSDMD oligomerizes into arc-, slit-shaped structures BibTex
2021-02-17 R-HSA-9647631 GSDMD (1-275) binds PIPs BibTex
2021-02-17 R-HSA-9710353 GSDMD (1-275) binds cardiolipin BibTex
2021-02-17 R-HSA-9710101 CASP4, CASP5 cleave GSDMD BibTex
2021-02-17 R-HSA-9710106 ELANE cleaves GSDMD BibTex
2021-02-17 R-HSA-9647680 CASP1 cleaves GSDMD BibTex
2021-02-17 R-HSA-9710294 GSDMD expression mediated by IRF2, IRF1 BibTex
2021-02-17 R-HSA-9710295 IRF2 or IRF1 binds the GSDMD gene promoter BibTex
2021-02-17 R-HSA-9710354 GSDME (1-270) binds cardiolipin BibTex
2021-02-17 R-HSA-9710263 GZMB cleaves GSDME BibTex
2021-02-17 R-HSA-9647632 CASP3 cleaves GSDME BibTex
2021-02-17 R-HSA-9710306 GSDME expression mediated by TP53, TP63 BibTex
2021-02-17 R-HSA-9710323 TP53 or TP63 binds the GSDME gene BibTex
2021-02-17 R-HSA-114284 Release of Cytochrome c from mitochondria BibTex
2021-02-17 R-HSA-6805981 HMGB1 release from cells BibTex
2021-01-27 R-HSA-9710963 p-STAT1dimer:KPNA1 binds KPNB1 BibTex
2021-01-27 R-HSA-9710959 p-STAT1 dimer binds KPNA1 BibTex
2021-01-27 R-HSA-9705323 Phosphorylation of TBK1/IKBKE BibTex
2021-01-27 R-HSA-9705145 TBK1, IKBKE form homodimers BibTex
2021-01-27 R-HSA-9689608 MPP5 binds SARS-CoV-1 E pentamer BibTex
2021-01-27 R-HSA-9705320 TBK1, IKBKE are autophosphorylated at Ser172 BibTex
2021-01-27 R-HSA-9705137 TBK1 or IKBKE forms homodimers BibTex
2021-01-27 R-HSA-9709852 MAVS:TOMM70 recruits HSP90:TBK1:IRF3 BibTex
2021-01-27 R-HSA-9709842 MAVS binds TOMM70 BibTex
2021-01-27 R-HSA-9709831 HSP90 binds TBK1 and IRF3 BibTex
2021-01-26 R-HSA-9731018 SARS-CoV-1 M binds to PDPK1 BibTex
2021-01-26 R-HSA-9727919 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to 14-3-3 proteins BibTex
2021-01-26 R-HSA-9737710 SARS-CoV-1 N binds SMAD3 and EP300 at the SERPINE1 gene promoter BibTex
2021-01-26 R-HSA-9727922 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to SMAD3 BibTex
2021-01-26 R-HSA-9727860 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to UBE2I BibTex
2021-01-26 R-HSA-9727908 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PSMC6 BibTex
2021-01-26 R-HSA-9727886 SARS-CoV-1 SUMO-p-N binds to NPM1 BibTex
2021-01-26 R-HSA-9727944 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to EEF1A1 BibTex
2021-01-26 R-HSA-9727869 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to HNRNPA1 BibTex
2021-01-26 R-HSA-9729232 SARS-CoV-1 nsp1 binds to 40S ribosomal subunit BibTex
2021-01-26 R-HSA-9731051 SARS-CoV-1 3b binds to RUNX1 BibTex
2021-01-26 R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA BibTex
2021-01-26 R-HSA-9685162 SARS-CoV-1 M protein interacts with TRAF3 BibTex
2021-01-26 R-HSA-9706977 6:KPNA2 binds KPNB1 BibTex
2021-01-26 R-HSA-9735840 SARS-CoV-1 7a binds BST2 BibTex
2021-01-26 R-HSA-9731047 SARS-CoV-1 6 binds to NMI BibTex
2021-01-26 R-HSA-9705959 SARS-CoV-1 6 binds KPNA2 BibTex
2021-01-26 R-HSA-9685281 SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome BibTex
2021-01-26 R-HSA-9728804 SARS-CoV-1 nsp1 binds to PPIase BibTex
2021-01-26 R-HSA-9685219 SARS-CoV-1 nsp3 deubiquinates K63-linked pUb oligo-TRAF6 (TLR7/8 signaling) BibTex
2021-01-26 R-HSA-9756603 SARS-CoV-1 S binds SFTPD 12mer BibTex
2021-01-26 R-HSA-9685179 SARS-CoV-1 N protein binds TRIM25 BibTex
2021-01-26 R-HSA-9731057 SARS-CoV-1 3a binds to caspase-1 BibTex
2021-01-26 R-HSA-9728776 SARS-CoV-1 nsp1 binds to RCAN3 BibTex
2021-01-26 R-HSA-9685195 SARS-CoV-1 9b recruits ITCH to MAVS BibTex
2021-01-26 R-HSA-9710988 SARS-CoV-1 M protein interacts with TBK1/IKBKE BibTex
2021-01-26 R-HSA-9685189 SARS-CoV-1 9b binds MAVS and PCBP2 BibTex
2021-01-26 R-HSA-9731009 SARS-CoV-1 nsp3 binds to IRF3 BibTex
2021-01-26 R-HSA-9731072 SARS-CoV-1 3a tetramer induces potassium efflux BibTex
2021-01-26 R-HSA-9731077 SARS-CoV-1 8b binds to IRF3 BibTex
2021-01-26 R-HSA-9731012 SARS-CoV-1 3a tetramerizes BibTex
2021-01-26 R-HSA-9709787 SARS-CoV-1 9b binds TOMM70 BibTex
2021-01-26 R-HSA-9685268 SARS-CoV-1 8b binds NLRP3 BibTex
2021-01-26 R-HSA-9711058 SARS-CoV-1 nsp3 deubiquinates K48-linked pUb IkBA BibTex
2021-01-26 R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 BibTex
2021-01-26 R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC BibTex
2021-01-26 R-HSA-9731031 SARS-CoV-1 6 binds to NPIPB3 BibTex
2021-01-26 R-HSA-9727857 SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PKL BibTex
2021-01-26 R-HSA-9704655 SARS-CoV-1 E binds BCL2L1 BibTex
2021-01-26 R-HSA-9704692 SARS-CoV-1 7a binds BCL2L1 BibTex
2021-01-26 R-HSA-9711016 SARS-CoV-1 nsp3 deubiquinates K63-linked pUb-STING BibTex
2021-01-26 R-HSA-9706720 SARS-CoV-1 E transports Ca2+ BibTex
2020-07-17 R-HSA-9695890 SPNS2,MFSD2B transport S1P from cytosol to extracellular region BibTex
2020-07-06 R-HSA-9693722 Unknown sepiapterin synthase transforms PTHP to sepiapterin BibTex
2020-06-26 R-HSA-9693929 RIPK1 variant is not cleaved by CASP8 BibTex
2020-06-26 R-HSA-9687455 HSV1 RIR1 binds RIPK3 BibTex
2020-06-26 R-HSA-9687465 HSV1 RIR1 binds RIPK1 BibTex
2020-06-26 R-HSA-9686343 IAV NS1 binds MLKL BibTex
2020-06-26 R-HSA-9687458 HSV1 RIR1 binds CASP8 BibTex
2020-06-26 R-HSA-9686338 SARS-CoV-1 3a binds the lysosomal membrane BibTex
2020-06-26 R-HSA-9686336 SARS-CoV-1 3a oligomerizes BibTex
2020-06-26 R-HSA-9686345 SARS-CoV-1 3a binds RIPK1:RIPK3 oligomer BibTex
2020-06-26 R-HSA-9688456 MLKL binds FLOT1, FLOT2 BibTex
2020-06-26 R-HSA-9686920 PELI1 ubiquitinates RIPK3 at K363 BibTex
2020-06-26 R-HSA-9687625 ATP binds MLKL BibTex
2020-06-26 R-HSA-9686922 PELI1 binds activated RIPK1:RIPK3 BibTex
2020-06-26 R-HSA-9688459 RIPK3 binds HSP90:CDC37 BibTex
2020-06-26 R-HSA-9688832 MLKL binds PDCD6IP and SDCBP BibTex
2020-06-26 R-HSA-9688831 STUB1 ubiquitinates RIPK3 at K55, K363 BibTex
2020-06-26 R-HSA-9688838 RIPK3 binds STUB1 BibTex
2020-06-26 R-HSA-9693978 Small molecule inhibitor binds RIPK1, RIPK3 BibTex
2020-06-26 R-HSA-9687828 O-GlcNAcylation of RIPK3 (TLR4 signaling) BibTex
2020-06-26 R-HSA-9687638 MLKL binds IP4, IP5 and IP6 BibTex
2020-06-26 R-HSA-9686930 RIPK3 is cleaved by CASP8 BibTex
2020-04-20 R-HSA-9684118 ERCC3-facilitated RNA Pol II backtracking in TC-NER BibTex
2020-04-20 R-HSA-6782131 ERCC2-facilitated RNA Pol II backtracking in TC-NER BibTex
2020-01-09 R-HSA-9668253 Hyperactivation of factor X by FVIIIa:FIXa R384L BibTex
2020-01-09 R-HSA-9661625 FVIII is secreted BibTex
2020-01-09 R-HSA-9670673 FIX is secreted BibTex
2020-01-09 R-HSA-9670014 Factor VIIIa dissociates BibTex
2020-01-09 R-HSA-9670049 Defects in F8 A1 domain accelerate dissociation of the A2 domain BibTex
2020-01-09 R-HSA-9670054 Defects in F8 A2 domain accelerate dissociation of the A2 domain BibTex
2020-01-09 R-HSA-9650473 SERPING1 is secreted BibTex
2020-01-09 R-HSA-9668023 TPST1,2 transfer SO4(2-) from PAPS to FVIII BibTex
2020-01-09 R-HSA-9668148 F8 variant is not sulfonated at Y1699 BibTex
2020-01-09 R-HSA-9666383 F8 variant is not cleaved by thrombin BibTex
2020-01-09 R-HSA-9670189 F8 variant does not bind the cell membrane BibTex
2020-01-09 R-HSA-9665809 F8 variant does not bind von Willebrand factor BibTex
2020-01-09 R-HSA-9661980 F8 variant is not secreted BibTex
2020-01-09 R-HSA-9668365 FVIIIa variant:FIXa does not convert FX to the active FXa BibTex
2020-01-09 R-HSA-9670888 F9 variant is not secreted BibTex
2020-01-09 R-HSA-9670874 FIXa variant:FVIIIa does not convert FX to the active FXa BibTex
2020-01-09 R-HSA-9673223 FIX(29-461) variant is not activated (factor XIa catalyst) BibTex
2020-01-09 R-HSA-9673231 GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) BibTex
2020-01-09 R-HSA-9651456 SERPING1 variant does not bind factor XIIa BibTex
2020-01-09 R-HSA-9651467 SERPING1 variant does not bind kallikrein BibTex
2020-01-09 R-HSA-9650447 SERPING1 variant is not secreted BibTex
2020-01-09 R-HSA-9653249 Cleavage of factor XII variant by activated thrombin BibTex
2020-01-09 R-HSA-9655046 Cleavage of FXII variant by KLKB1 BibTex
2019-10-03 R-HSA-9661710 An unknown oxidase oxidises D-UBGN to UBN BibTex
2019-10-03 R-HSA-9661726 An unknown reductase reduces D-UBGN to STBN BibTex
2019-10-03 R-HSA-9661745 An unknown BILR reduces BIL to D-UBGN BibTex
2019-10-03 R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL BibTex
2019-10-03 R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region BibTex
2019-10-03 R-HSA-9661446 BMG, BDG translocates from ER lumen to cytosol BibTex
2019-10-03 R-HSA-9663492 BIL dissociates from GSTA1, FABP1 BibTex
2019-10-03 R-HSA-9663511 BIL binds GSTA1, FABP1 BibTex
2019-10-03 R-HSA-9661723 SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) BibTex
2019-10-03 R-HSA-9661397 SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) BibTex
2019-10-03 R-HSA-9661799 SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) BibTex
2019-10-03 R-HSA-9661425 BIL:ALB dissociates BibTex
2019-10-03 R-HSA-9661432 BIL binds ALB BibTex
2019-10-03 R-HSA-9661405 ABCC1 transports BIL from cytosol to extracellular region (blood) BibTex
2019-10-03 R-HSA-9661419 ALB binds extracellular heme BibTex
2019-10-03 R-HSA-9661408 FLVCR1-2 transports heme from mitochondrial matrix to cytosol BibTex
2019-09-11 R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 BibTex
2019-08-12 R-HSA-9610152 Activated BRAF recruits MAP2Ks and MAPKs to the endosome BibTex
2019-08-12 R-HSA-9610154 Dissociation of phosphorylated MAP2Ks and MAPKs BibTex
2019-08-12 R-HSA-9610156 MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF BibTex
2019-08-12 R-HSA-9610153 Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF BibTex
2019-08-12 R-HSA-9610163 BRAF autophosphorylates downstream of RAP1 and NGF BibTex
2019-05-17 R-HSA-1449687 Corticosteroids bind to CBG in blood BibTex
2019-04-03 R-HSA-9640316 DeHA hydrolyses to threonate and oxalate BibTex
2019-04-03 R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate BibTex
2019-04-03 R-HSA-9640307 DeHA hydrolyses to 2,3-DKG BibTex
2019-04-03 R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA BibTex
2018-12-29 R-HSA-9657775 Expression of ANGPTL3 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9657836 NR1H2,3 binds the ANGPTL3 gene BibTex
2018-12-29 R-HSA-9605060 Expression of SCD regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9028526 NR1H2 or NR1H3, NRIP1 bind the SCD gene BibTex
2018-12-29 R-HSA-9605063 Expression of FASN regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9028533 NR1H2,3, NRIP1 bind the FASN gene BibTex
2018-12-29 R-HSA-9605056 Expression of SREBF1 (SREBP1) regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9028525 NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene BibTex
2018-12-29 R-HSA-9605051 Expression of PCK1 regulated by NR1H3 BibTex
2018-12-29 R-HSA-9028524 NR1H3, NRIP1 bind the PCK1 gene BibTex
2018-12-29 R-HSA-9623365 Expression of MYLIP regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9623366 NR1H2,3 binds the MYLIP gene BibTex
2018-12-29 R-HSA-9607342 Expression of FABP6 regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9608039 NR1H2,3 binds the PLIN1 gene BibTex
2018-12-29 R-HSA-9608048 Expression of PLIN1 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9035279 Expression of APOC4 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9024326 Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex BibTex
2018-12-29 R-HSA-9024334 Co-repressor complex dissociates from the transcription unit of the ABCA1 gene BibTex
2018-12-29 R-HSA-9618407 NR1H2,3 binds the ARL4C gene BibTex
2018-12-29 R-HSA-9618394 ARL4C gene transcription regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9618392 miR-26 binds to the 3'UTR of the ARL4C mRNA BibTex
2018-12-29 R-HSA-9024386 Oxysterol-induced binding of NR1H2,3:RXR to the ABCG1 gene BibTex
2018-12-29 R-HSA-9035143 NR1H2,3 binds the APOC4 gene BibTex
2018-12-29 R-HSA-9605057 ABCA1 gene transcription regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9624925 miR-33 binds to the 3'UTR of the ABCA1 mRNA BibTex
2018-12-29 R-HSA-9031522 NR1H2,3 binds the APOE gene BibTex
2018-12-29 R-HSA-9031512 Expression of APOE regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9029531 Expression of ABCG5 regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9035167 NR1H2,3 binds the EEPD1 gene BibTex
2018-12-29 R-HSA-9031518 NR1H2,3 binds the APOC1 gene BibTex
2018-12-29 R-HSA-9029521 NR1H2,3 binds the ABCG5 gene BibTex
2018-12-29 R-HSA-9035281 NR1H3 gene transcription regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9038545 miR-613 binds to the 3'UTR of the NR1H3 mRNA BibTex
2018-12-29 R-HSA-9029591 Expression of ABCG8 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9031510 Expression of APOC1 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9024361 Expression of ABCG1 regulated by NR1H2,3 BibTex
2018-12-29 R-HSA-9618486 miR-26 binds to the 3'UTR of the ABCA1 mRNA BibTex
2018-12-29 R-HSA-9035180 Expression of EEPD1 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9029551 NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex BibTex
2018-12-29 R-HSA-9035133 NR1H2,3 binds the CETP gene BibTex
2018-12-29 R-HSA-9035169 Expression of CETP regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9031521 NR1H2,3 binds the APOC2 gene BibTex
2018-12-29 R-HSA-9657786 NR1H2,3 binds the APOD gene BibTex
2018-12-29 R-HSA-9657791 miR-144 binds to the 3'UTR of the ABCA1 mRNA BibTex
2018-12-29 R-HSA-9031527 Expression of APOC2 regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9605052 NR1H3 mRNA is translated BibTex
2018-12-29 R-HSA-9029561 NCOA1 recruits EP300 to the ABCA1 promoter BibTex
2018-12-29 R-HSA-9624353 NR1H2,3 binds the PLTP gene BibTex
2018-12-29 R-HSA-9657767 Expression of APOD regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9618405 ARL4C mRNA is translated BibTex
2018-12-29 R-HSA-9035185 NR1H2,3 binds the NR1H3 gene BibTex
2018-12-29 R-HSA-9029555 NR1H2,3 binds the ABCG8 gene BibTex
2018-12-29 R-HSA-9618479 ABCA1 mRNA is translated BibTex
2018-12-29 R-HSA-9619756 NR1H2 binds ABCA1 BibTex
2018-12-29 R-HSA-9624365 Expression of PLTP regulated by NR1H2 or NR1H3 BibTex
2018-12-29 R-HSA-9631296 NR1H2,3 binds the FABP6 gene BibTex
2018-12-29 R-HSA-9029517 Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex BibTex
2018-12-29 R-HSA-9029566 Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene BibTex
2018-12-29 R-HSA-9029580 NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex BibTex
2018-12-29 R-HSA-9029536 Expression of UGT1A3 BibTex
2018-12-22 R-HSA-434382 ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell BibTex
2018-12-22 R-HSA-434381 CD36 (FAT) translocates palmitate from the extracellular region to the cytosol BibTex
2018-12-04 R-HSA-9630921 NFKBIA variant binds NFkB complex BibTex
2018-12-04 R-HSA-9630923 NF-kappa-B inhibitor binds NF-kappa-B complex BibTex
2018-07-27 R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors BibTex
2018-07-27 R-RNO-9614350 Glycine and glutamate ligands bind Grin1:Grin2a NMDA receptor BibTex
2018-07-27 R-HSA-9614185 Mg2+ binds GRIN1:GRIN2 NMDA receptors BibTex
2018-07-27 R-RNO-9614228 Mg2+ binds Grin1:Grin2 NMDA receptors BibTex
2017-12-02 R-HSA-9009941 RNASEL cleaves viral ssRNA BibTex
2017-12-02 R-HSA-9009936 RNASEL cleaves cellular ssRNA BibTex
2017-12-02 R-HSA-8985201 ABCE1 binds RNASEL BibTex
2017-12-02 R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates BibTex
2017-12-02 R-HSA-8985123 RNASEL binds 2'-5' oligoadenylate BibTex
2017-12-02 R-HSA-8985104 OAS2 produces oligoadenylates BibTex
2017-12-02 R-HSA-8985091 OAS3 produces oligoadenylates BibTex
2017-12-02 R-HSA-8985157 OAS3 binds viral dsRNA BibTex
2017-12-02 R-HSA-8983680 OAS1 produces oligoadenylates BibTex
2017-12-02 R-HSA-8985153 OASL binds DDX58 BibTex
2017-12-02 R-HSA-8983688 OAS1 oligomerizes BibTex
2017-12-02 R-HSA-8983671 OAS1 binds viral dsRNA BibTex
2017-12-02 R-HSA-8985097 OAS2 dimerizes BibTex
2017-12-02 R-HSA-8985138 OAS2 binds viral dsRNA BibTex
2017-10-25 R-HSA-9029434 p-S363,S380,T573 RS6K translocates to the nucleus BibTex
2017-06-14 R-HSA-8963864 CUBN dissociates from 25(OH)D BibTex
2017-06-14 R-HSA-8963851 VD3 dissociates from GC BibTex
2017-06-14 R-HSA-209738 VD3 binds GC BibTex
2017-02-24 R-HSA-8877153 STARD7 binds PC BibTex
2017-02-06 R-HSA-8960973 RLBP1:11cRAL dissociates BibTex
2017-02-06 R-HSA-8959798 SLC30A10 transports Mn2+ from cytosol to extracellular region BibTex
2017-02-06 R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P BibTex
2017-02-06 R-HSA-8954513 NAA translocates from mitochondrial matrix to cytosol BibTex
2017-02-06 R-HSA-8959781 SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix BibTex
2017-02-06 R-HSA-8961021 SFTPD binds with itself to form SFTPD 12mer BibTex
2017-01-30 R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL BibTex
2017-01-30 R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL BibTex
2017-01-30 R-HSA-8959462 SAMD8 transfers phosphatidyl from PE onto C16DH CER BibTex
2017-01-30 R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP BibTex
2017-01-30 R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ BibTex
2017-01-30 R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-5COOH BibTex
2017-01-30 R-HSA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA BibTex
2017-01-30 R-HSA-8955794 PGP:Mg2+ dimer hydrolyses 3PG to glycerol BibTex
2017-01-30 R-RNO-8955775 Pgp:Mg2+ dimer hydrolyses 3PG to glycerol BibTex
2017-01-30 R-HSA-8955844 RBKS phosphorylates ribose to R5P BibTex
2017-01-30 R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP BibTex
2017-01-11 R-HSA-5678327 MIOX oxidises Ins to GlcA BibTex
2017-01-11 R-HSA-8955010 LRTOMT transfers Met to DA, forming 3MT BibTex
2017-01-11 R-HSA-6806877 NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs BibTex
2017-01-11 R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ BibTex
2017-01-11 R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA BibTex
2017-01-11 R-HSA-5691150 TFR2 dimer binds 2xholoTF BibTex
2017-01-11 R-HSA-5691154 HFE binds TFRC dimer BibTex
2017-01-11 R-HSA-8952726 SLC38A9 transports L-Arg from lysosomal lumen to cytosol BibTex
2017-01-11 R-HSA-8952716 SLC38A9 binds Ragulator:Rag dimers BibTex
2017-01-11 R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG BibTex
2017-01-06 R-HSA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 BibTex
2017-01-06 R-HSA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) BibTex
2017-01-06 R-HSA-8953398 PIR oxygenates quercetin BibTex
2017-01-06 R-HSA-8953336 Expression of EXTL1 BibTex
2017-01-06 R-HSA-8953356 Expression of EXTL2 BibTex
2017-01-06 R-HSA-8951850 TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane BibTex
2017-01-06 R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN BibTex
2017-01-06 R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates BibTex
2017-01-06 R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP BibTex
2017-01-06 R-HSA-8954262 TPST1,2 transfer SO4(2-) from PAPS to PODXL2 BibTex
2017-01-06 R-HSA-8941543 VRAC heteromer transports I-, Cl- from cytosol to extracellular region BibTex
2017-01-06 R-HSA-8953339 DNPH1 hydrolyses dGMP BibTex
2017-01-06 R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA BibTex
2017-01-06 R-HSA-5690886 ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs BibTex
2017-01-06 R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) BibTex
2017-01-06 R-HSA-5691131 CANDI binds CUL1 BibTex
2017-01-06 R-HSA-5691108 SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 BibTex
2017-01-06 R-HSA-5691176 NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) BibTex
2017-01-06 R-HSA-5691167 CUL1, SKP1, FBXL5 bind BibTex
2017-01-06 R-HSA-5690911 ACO1:4Fe-4S isomerises CIT to ISCIT BibTex
2017-01-06 R-HSA-5690873 ACO1 binds 4Fe-4S BibTex
2017-01-06 R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) BibTex
2016-11-15 R-HSA-6805205 GPR35 binds kynurenic acid BibTex
2016-11-15 R-HSA-8876868 ECE1 cleaves EDN1(53-90) BibTex
2016-11-15 R-HSA-8877620 ECE2 cleaves EDN1(53-90) BibTex
2016-11-15 R-HSA-8851679 GPR183 binds 7alpha,25-dihydroxycholesterol BibTex
2016-10-28 R-HSA-8939039 PPANT translocates from extracellular region to cytosol BibTex
2016-10-28 R-HSA-8938300 Vanin hydrolyses pantetheine to PanK, 2AET BibTex
2016-10-28 R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP BibTex
2016-10-19 R-HSA-8876731 CHEST translocates from ER membrane to lipid particle BibTex
2016-10-19 R-HSA-8876696 SOAT1,2 transfer acyl group to CHOL forming CHEST BibTex
2016-10-19 R-HSA-8876485 CHOL translocates from lysosome membrane to ER membrane BibTex
2016-10-19 R-HSA-8876484 NPC2 transfers CHOL to NPC1 BibTex
2016-10-19 R-HSA-8876472 NPC2 binds CHOL BibTex
2016-10-19 R-HSA-8876366 LDL translocates from endosome lumen to lysosome lumen BibTex
2016-10-19 R-HSA-8941915 Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes BibTex
2016-10-19 R-HSA-8941895 Formation of CDK4/6:CCND complexes BibTex
2016-10-17 R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) BibTex
2016-10-11 R-HSA-8937631 CRHR2-2 binds CRH,UCN,UCN2,UCN3 BibTex
2016-10-11 R-HSA-8937613 CRHBP binds CRH BibTex
2016-10-11 R-HSA-8940388 GPLD1 hydrolyses GPI-anchors from proteins BibTex
2016-10-11 R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds BibTex
2016-10-11 R-HSA-8937191 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates BibTex
2016-10-11 R-HSA-8936851 AHRR binds ARNT BibTex
2016-10-11 R-HSA-8937169 AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm BibTex
2016-10-11 R-HSA-8936849 AHR:2xHSP90:AIP:PTGES3 binds TCDD BibTex
2016-10-11 R-HSA-8937177 AHR:TCDD binds ARNT BibTex
2016-10-11 R-HSA-8936519 NQO2:FAD dimer reduces quinones to hydroquinones BibTex
2016-10-11 R-HSA-8937419 CBR3 reduces DOX to DOXOL BibTex
2016-10-11 R-HSA-6803255 HCOOH translocated from mitochondrial matrix to cytosol BibTex
2016-10-11 R-HSA-8942344 FOLR2 transports FOLA from extracellular region to cytosol BibTex
2016-10-11 R-HSA-8940134 FOLR2 binds FOLA BibTex
2016-10-11 R-HSA-8936356 GUCY2C trimer binds sta1 BibTex
2016-10-11 R-HSA-8936214 GUCY2C trimer binds GUCA2A,B BibTex
2016-10-11 R-HSA-8937369 ATAD2 binds ESR1 BibTex
2016-10-11 R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ BibTex
2016-10-11 R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN BibTex
2016-10-11 R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose BibTex
2016-10-11 R-HSA-5359451 NNMT transfers CH3 from SAM to NAM to form MNA BibTex
2016-10-11 R-HSA-8869603 SLC22A13 transports NCA from extracellular region to cytosol BibTex
2016-10-11 R-HSA-8938073 PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) BibTex
2016-10-11 R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ BibTex
2016-10-11 R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose BibTex
2016-10-11 R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN BibTex
2016-10-11 R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN BibTex
2016-10-11 R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN BibTex
2016-10-11 R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN BibTex
2016-08-12 R-HSA-8878654 ACP6 hydrolyses MYS-LPA BibTex
2016-08-12 R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA BibTex
2016-08-12 R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE BibTex
2016-08-12 R-HSA-8931653 POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 BibTex
2016-08-12 R-HSA-8879117 POMGNT2 transfers GlcNAc to Man-DAG1 BibTex
2016-08-12 R-HSA-8931648 B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 BibTex
2016-08-12 R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters BibTex
2016-08-12 R-HSA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 BibTex
2016-08-12 R-HSA-8933258 LSR trimer binds LDL BibTex
2016-08-12 R-MMU-8933256 Lsr trimer binds LDL BibTex
2016-08-12 R-HSA-8933292 LSR trimer binds VLDL BibTex
2016-08-12 R-MMU-8933295 Lsr trimer binds VLDL BibTex
2016-08-12 R-HSA-8932599 CALB1 binds 4xCa2+ BibTex
2016-08-12 R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer BibTex
2016-08-12 R-HSA-8878581 TYRP1 oxidises DHICA to IQCA BibTex
2016-08-12 R-HSA-8932851 PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol BibTex
2016-08-12 R-HSA-8878664 SLC4A4 cotransports Na+ with 3HCO3- BibTex
2016-08-12 R-HSA-8933547 MCAT transfers Mal from Mal-CoA to NDUFAB1 BibTex
2016-08-12 R-HSA-8932980 SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane BibTex
2016-07-15 R-HSA-8874979 ACBD3 binds GOLGB1 BibTex
2016-07-15 R-HSA-8874718 TTPA binds alpha-TOH BibTex
2016-07-15 R-HSA-8874705 TTPA transports alpha-TOH from lysosomal membrane to plasma membrane BibTex
2016-07-15 R-HSA-8870332 PTPN13:PLEKHA1,2 bind PI(3,4)P2 BibTex
2016-07-15 R-HSA-8870499 PLEKHA3,8 bind PI4P, ARF1 BibTex
2016-07-15 R-HSA-8870489 PLEKHA4,(5,6) bind PI3P BibTex
2016-07-15 R-HSA-8871376 p-Y389,400-RUFY1 binds PI3P BibTex
2016-07-15 R-HSA-8871370 p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane BibTex
2016-07-15 R-HSA-8871373 BMX phosphorylates RUFY1 BibTex
2016-07-15 R-HSA-8871366 p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP BibTex
2016-07-15 R-HSA-8874470 TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane BibTex
2016-07-15 R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM BibTex
2016-07-15 R-HSA-8869241 PITPNM1,2,3 exchange PI for PA BibTex
2016-07-15 R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS BibTex
2016-07-15 R-HSA-8873929 Casein kinase II phosphorylates STARD10 BibTex
2016-07-15 R-HSA-8873834 STARD10 transports PC from ER membrane to lamellar body membrane BibTex
2016-07-15 R-HSA-8873794 PCTP binds PC BibTex
2016-07-15 R-HSA-8873923 STARD10 binds LPCAT1 and PC BibTex
2016-07-15 R-HSA-8865637 MFSD2A transports LPC from extracellular region to plasma membrane BibTex
2016-07-15 R-HSA-8873830 STARD7 transports PC from ER membrane to mitochondrial outer membrane BibTex
2016-07-15 R-RNO-8873889 Stard7 transports PC from ER membrane to mitochondrial outer membrane BibTex
2016-07-15 R-HSA-8866941 MID1IP1 binds THRSP BibTex
2016-07-15 R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate BibTex
2016-07-15 R-HSA-8873850 STARD5 binds DCA, LCA BibTex
2016-07-15 R-HSA-8875838 SLC25A19 transports ThDP from cytosol to mitochondrial matrix BibTex
2016-07-15 R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids BibTex
2016-07-15 R-HSA-8876283 SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol BibTex
2016-07-15 R-HSA-8875902 SLC45A3 transports Glc from extracellular region to cytosol BibTex
2016-07-15 R-HSA-8876319 SLC50A1 transports Glc from cytosol to extracellular region BibTex
2016-07-15 R-HSA-8871506 SORL1 transports APP(18-770) from endosome lumen to Golgi lumen BibTex
2016-07-15 R-HSA-8871494 SORL1 binds APP(18-770) BibTex
2016-07-15 R-HSA-8875071 ACSS3 ligates CoA to CH3COO- BibTex
2016-07-15 R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA BibTex
2016-07-15 R-MMU-8875095 Slc27a3 ligates CoA to VLCFA BibTex
2016-07-15 R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol BibTex
2016-07-15 R-HSA-8875871 SLC26A11 transports SO4(2-) from extracellular region to cytosol BibTex
2016-07-15 R-HSA-8874745 ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH BibTex
2016-07-15 R-HSA-8875013 ACSM3,ACSM6 ligate CoA to BUT BibTex
2016-07-15 R-MMU-8875039 Acsm3 ligates CoA to BUT BibTex
2016-07-15 R-HSA-8867344 OMA1 hydrolyses OPA1 BibTex
2016-07-15 R-HSA-8875623 SLC25A18,22 import L-Glu, H+ BibTex
2016-07-15 R-HSA-8868402 OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane BibTex
2016-07-15 R-HSA-8867667 OSBPs transport 25OH-CHOL from ER membrane to plasma membrane BibTex
2016-07-15 R-HSA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane BibTex
2016-04-23 R-HSA-8866858 CFTR F508del is degraded by the 26S proteasome BibTex
2016-04-23 R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol BibTex
2016-04-23 R-HSA-8866856 RNF5 and RNF185 ubiquitinate CFTR F508del BibTex
2016-04-23 R-HSA-8866857 CFTR F508del binds components of the ERAD machinery for ubiquitination and degradation BibTex
2016-04-23 R-HSA-8866553 misfolded CFTR is degraded by the 26S proteasome BibTex
2016-04-23 R-HSA-8866551 CFTR binds components of the ERAD machinery for ubiquitination and degradation BibTex
2016-04-23 R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol BibTex
2016-04-23 R-HSA-8866546 RNF5 and RNF185 ubiquitinate misfolded CFTR BibTex
2016-04-23 R-HSA-8866851 CFTR transits to the plasma membrane BibTex
2016-04-20 R-HSA-6784738 Degradation of PCSK9:LDLR:Clathrin-coated vesicle BibTex
2016-04-20 R-HSA-6784729 PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome BibTex
2016-04-20 R-HSA-6784735 PCSK9:LDLR bind to Clathrin BibTex
2016-04-20 R-HSA-6784734 PCSK9 binds LDLR BibTex
2016-04-20 R-HSA-6784622 APOA4,APOA5,APOC2,CIDEC,FGF21 genes express APOA4,APOA5,APOC2,CIDEC,FGF21 proteins BibTex
2016-04-20 R-MMU-6784616 Apoa4 gene,Apoa5 gene,Apoc2 gene,Cidec gene,Fgf21 gene transcription and traduction to Apoa4,Apoa5,Apoc2,Cidec,Fgf21 BibTex
2016-04-20 R-HSA-6784648 CREB3L3 (1-?) translocates from cytosol to nucleoplasm BibTex
2016-04-20 R-MMU-6784652 Creb3l3 (1-?) translocates from cytosol to nucleoplasm BibTex
2016-04-20 R-HSA-6784620 MBTPS1,2 cleaves CREB3L3 to CREB3L3(1-?) and CREB3L3(?-461) BibTex
2016-04-20 R-MMU-6784684 Mbtps1,2 cleaves Creb3l3 to Creb3l3(1-?) and Creb3l3(?-461) BibTex
2016-04-20 R-HSA-6784676 PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer BibTex
2016-04-20 R-HSA-6784628 PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer BibTex
2016-04-20 R-HSA-6784861 HSPG binds LPL dimer BibTex
2016-04-05 R-HSA-8858298 HRASLS transfer acyl group from PC to PE to form NAPE BibTex
2016-04-05 R-HSA-8862380 HSD17B13 binds lipid droplets BibTex
2016-04-05 R-HSA-8858270 HILPDA binds lipid droplets BibTex
2016-04-05 R-HSA-8857686 FITM1, FITM2 bind TAGs BibTex
2016-04-05 R-HSA-8856630 CIDEA:CIDEC binds lipid droplets BibTex
2016-04-05 R-HSA-8857692 RNA demethylases demethylate N6-methyladenosine RNA BibTex
2016-04-05 R-HSA-8848663 ADIPOQ trimer binds ADIPOR dimers BibTex
2016-04-05 R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) BibTex
2016-04-05 R-HSA-8855237 FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 BibTex
2016-04-05 R-HSA-8855259 RELN:VLDLR:DAB1 binds SH3KBP1 BibTex
2016-04-05 R-HSA-8855232 RELN:VLDLR binds DAB1 BibTex
2016-04-05 R-HSA-8854466 VLDLR binds RELN BibTex
2016-04-05 R-HSA-8855130 VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane BibTex
2016-04-05 R-HSA-8855131 VLDLR:PCSK9 binds Clathrin-coated vesicles BibTex
2016-04-05 R-HSA-8854628 MYLIP dimer ubiquitinates VLDLR on Lys-839 BibTex
2016-04-05 R-HSA-8855111 VLDLR binds PCSK9 BibTex
2016-04-05 R-HSA-8854408 APOBR dimer binds VLDLs BibTex
2016-04-05 R-HSA-8854462 VLDLR binds VLDL BibTex
2016-04-05 R-HSA-8858252 HDLBP binds HDL BibTex
2016-04-05 R-HSA-8856525 ANGPTL8 binds ANGPTL3 BibTex
2016-04-05 R-HSA-8857928 GPIHBP1 binds HSPG:LPL dimer BibTex
2016-04-05 R-HSA-8866321 VLDL binds APOC1 and APOC4 BibTex
2016-04-05 R-HSA-8866327 VLDL translocates from SER lumen to extracellular region BibTex
2016-04-05 R-HSA-8866304 pre-VLDL binds lipids to form VLDL BibTex
2016-04-05 R-HSA-8866308 pre-VLDL translocates from RER membrane to SER lumen BibTex
2016-04-05 R-HSA-8866329 MTTP lipidates APOB-100, forming a pre-VLDL BibTex
2016-04-05 R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol BibTex
2016-04-05 R-HSA-8855711 PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins BibTex
2016-04-05 R-HSA-8857662 ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane BibTex
2016-04-05 R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides BibTex
2016-04-05 R-HSA-8855954 B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD BibTex
2016-04-05 R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins BibTex
2016-04-05 R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) BibTex
2016-04-05 R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA BibTex
2016-04-05 R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP BibTex
2016-04-05 R-HSA-8848250 ACBD6 binds LCFA-CoA BibTex
2016-04-05 R-HSA-8848246 DBI, ACBD7 bind MCFA-CoA and LCFA-CoA BibTex
2016-04-05 R-HSA-8848247 ACBD4,5 bind MCFA-CoA and LCFA-CoA BibTex
2016-01-26 R-HSA-8853710 MANBA hydrolyses GlcNAc:Man BibTex
2016-01-26 R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 BibTex
2016-01-26 R-HSA-8853391 GlcNAc (Man)5 translocates from cytosol to lysosomal lumen BibTex
2016-01-15 R-HSA-5682101 PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer BibTex
2016-01-15 R-HSA-5682103 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane BibTex
2016-01-15 R-HSA-5682084 ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer BibTex
2016-01-11 R-HSA-8852552 MST1R autophosphorylates BibTex
2016-01-11 R-HSA-8852522 MST1 dimer:MST1R dimer binds MST1R dimer BibTex
2016-01-11 R-HSA-6800315 MST1 binds MST1R BibTex
2016-01-11 R-HSA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer BibTex
2016-01-11 R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P BibTex
2016-01-11 R-HSA-6800299 HGFAC cleaves pro-HGF to form HGF dimer BibTex
2016-01-11 R-HSA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer BibTex
2016-01-11 R-HSA-6800298 HGF dimer binds MET BibTex
2016-01-11 R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine BibTex
2016-01-11 R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT BibTex
2016-01-11 R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT BibTex
2016-01-11 R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT BibTex
2016-01-11 R-HSA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG BibTex
2016-01-11 R-HSA-6813749 ALDH1A1 oxidises GA to DGA BibTex
2016-01-11 R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA BibTex
2016-01-11 R-HSA-6798667 TDH tetramer oxidises L-Thr to 2A-3OB BibTex
2016-01-11 R-HSA-6798345 PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA BibTex
2016-01-11 R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC BibTex
2016-01-11 R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- BibTex
2016-01-11 R-HSA-6799695 GPX5,6 reduce H2O2 to H2O BibTex
2016-01-11 R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp BibTex
2016-01-11 R-HSA-6806966 APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX BibTex
2016-01-11 R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH BibTex
2016-01-11 R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH BibTex
2016-01-11 R-HSA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix BibTex
2016-01-11 R-HSA-6797955 ALDH7A1 oxidises BETALD to BET BibTex
2016-01-11 R-HSA-6797957 BET translocates from mitochondrial matrix to cytosol BibTex
2016-01-11 R-HSA-6814153 ADO oxidises 2AET to HTAU BibTex
2016-01-11 R-HSA-6797962 DMGLY translocates from cytosol to mitochondrial matrix BibTex
2016-01-11 R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC BibTex
2016-01-11 R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly BibTex
2016-01-11 R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 BibTex
2016-01-11 R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man BibTex
2016-01-11 R-HSA-6803761 RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc BibTex
2016-01-11 R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P BibTex
2016-01-11 R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA BibTex
2016-01-11 R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA BibTex
2016-01-11 R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP BibTex
2016-01-11 R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP BibTex
2016-01-11 R-HSA-6806831 CYB5Rs reduce MetHb to HbA BibTex
2016-01-11 R-HSA-6800149 N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII BibTex
2016-01-11 R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins BibTex
2016-01-11 R-HSA-6801328 MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF BibTex
2016-01-11 R-HSA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF BibTex
2016-01-11 R-HSA-6801456 MTHFD1L transforms 10-formyl-THF to HCOOH and THF BibTex
2016-01-11 R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG BibTex
2016-01-11 R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) BibTex
2016-01-11 R-HSA-76494 POR reduces CYP450:Fe3+ to CYP450:Fe2+ BibTex
2016-01-11 R-HSA-6800334 MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG BibTex
2016-01-11 R-HSA-6800138 N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer BibTex
2016-01-05 R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane BibTex
2015-12-14 R-HSA-8848658 CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins BibTex
2015-11-16 R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region BibTex
2015-11-16 R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region BibTex
2015-11-02 R-HSA-6807242 25(OH)D translocates from ER membrane to extracellular region BibTex
2015-09-14 R-HSA-6786650 DDHD1,2 hydrolyse PA BibTex
2015-09-14 R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA BibTex
2015-09-14 R-HSA-6786205 KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 BibTex
2015-09-14 R-HSA-6786012 CHST4 transfers SO4(2-) from PAPS to Core 2 mucins BibTex
2015-09-14 R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE BibTex
2015-09-14 R-HSA-6784959 BPHL hydrolyses VACV to ACV BibTex
2015-09-14 R-HSA-6786190 CMBL hydrolyses OM to OLMS BibTex
2015-09-14 R-HSA-6788650 ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins BibTex
2015-09-14 R-HSA-6788867 FN3K phosphorylates ketosamines BibTex
2015-09-14 R-HSA-6788855 FN3KRP phosphorylates PsiAm, RibAm BibTex
2015-09-14 R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP BibTex
2015-09-14 R-HSA-6786421 CHIA hydrolyses chitin BibTex
2015-09-14 R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA BibTex
2015-09-14 R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH BibTex
2015-09-14 R-HSA-6785928 CHAC1,2 cleaves GSH to OPRO and CysGly BibTex
2015-09-14 R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA BibTex
2015-09-14 R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP BibTex
2015-09-14 R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi BibTex
2015-09-14 R-HSA-6786257 DCTPP1 hydrolyses 5idCTP BibTex
2015-09-14 R-MMU-6786295 Dctpp1 hydrolyses 5idCTP BibTex
2015-09-14 R-HSA-6788810 AK6 phosphorylates (d)NMPs to (d)NDPs BibTex
2015-09-14 R-HSA-6788798 AK4 phosphorylates (d)NMPs to (d)NDPs BibTex
2015-09-14 R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO BibTex
2015-09-14 R-HSA-6787329 PGM2:Mg2+ isomerises R1P to R5P BibTex
2015-09-14 R-HSA-8982667 PGM2:Mg2+ isomerises dR1P to dR5P BibTex
2015-09-14 R-HSA-6786048 CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 BibTex
2015-09-14 R-HSA-6786034 CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin BibTex
2015-09-14 R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA BibTex
2015-09-14 R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc BibTex
2015-09-14 R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc BibTex
2015-09-14 R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P BibTex
2015-09-14 R-HSA-6787677 FUOM isomerises alpha-Fuc to beta-Fuc BibTex
2015-09-14 R-HSA-6787623 TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal BibTex
2015-09-14 R-HSA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan BibTex
2015-09-14 R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN BibTex
2015-09-14 R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs BibTex
2015-09-14 R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA BibTex
2015-09-14 R-HSA-6788611 HYKK phosphorylates 5HLYS BibTex
2015-09-14 R-HSA-6793591 LIAS synthesizes lipoyl-GCSH BibTex
2015-09-14 R-HSA-6793590 LIPT2 transfers octanoyl group to GCSH BibTex
2015-09-14 R-HSA-6792572 LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST BibTex
2015-09-14 R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM BibTex
2015-09-14 R-HSA-6786720 DECR2 reduces LCtE-CoA to t3enoyl-CoA BibTex
2015-09-12 R-HSA-5432814 SFTPA/SFTPD binds TLR2:TLR1 BibTex
2015-09-12 R-HSA-6804099 HMGB1 binds LTP BibTex
2015-09-12 R-HSA-6804100 HMGB1 binds LPS BibTex
2015-09-12 R-HSA-5432852 SFTPA/SFTPD binds TLR4:LY96 BibTex
2015-09-12 R-HSA-5432825 HMGB1 binds TLR4:LY96 BibTex
2015-09-12 R-HSA-6805981 HMGB1 release from cells BibTex
2015-09-12 R-HSA-5432849 S100A8:S100A9 binds TLR4:LY96 BibTex
2015-09-12 R-HSA-6805943 S100A1 binds TLR4:LY96 BibTex
2015-08-17 R-HSA-5688899 Defective CSF2RA does not bind SFTPs BibTex
2015-08-17 R-HSA-5687875 Defective SFTPA2 does not translocate from ER membrane to extracellular region BibTex
2015-08-17 R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body BibTex
2015-08-17 R-HSA-5688025 Defective pro-SFTPB does not translocate from ER membrane to multivesicle body BibTex
2015-08-17 R-HSA-5687585 Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol BibTex
2015-08-17 R-HSA-5688884 Defective CSF2RB does not bind SFTPs BibTex
2015-08-17 R-HSA-5683888 LMCD1 binds GATA6, sequestering it BibTex
2015-08-17 R-HSA-5687284 DMBT1 binds SFTPD 12mer, SFTPAs BibTex
2015-08-17 R-HSA-5686286 PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body BibTex
2015-08-17 R-HSA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC BibTex
2015-08-17 R-HSA-9624778 SFTPD 12mer translocates from ER membrane to extracellular region BibTex
2015-08-17 R-HSA-5685290 SFTPD gene produces SFTPD protein BibTex
2015-08-17 R-HSA-5684865 SFTPB dimer,C translocate from multivesicle body to lamellar body BibTex
2015-08-17 R-HSA-6791016 SFTPB binds itself BibTex
2015-08-17 R-HSA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB BibTex
2015-08-17 R-HSA-5686301 PALM-C100-CKAP4 binds SFTPAs BibTex
2015-08-17 R-HSA-5686304 ZDHHC2 transfers PALM from PALM-CoA to CKAP4 BibTex
2015-08-17 R-HSA-9624789 pro-SFTPB translocates from ER membrane to multivesicle body BibTex
2015-08-17 R-HSA-5683840 SFTPB gene produces pro-SFTPB protein BibTex
2015-08-17 R-HSA-5685208 CCDC59:TTF1 binds SFTPB gene BibTex
2015-08-17 R-HSA-5686359 SFTPs translocate from extracellular region to clathrin-coated vesicle BibTex
2015-08-17 R-HSA-5686335 CSF2RA:CSF2RB binds SFTPs BibTex
2015-08-17 R-HSA-5684862 SFTPB,C, PC, PG translocate from lamellar body to extracellular region. BibTex
2015-08-17 R-HSA-5685649 SFTPAs translocate from ER membrane to extracellular region BibTex
2015-08-17 R-HSA-5683879 SFTPA genes produce SFTPA proteins BibTex
2015-08-17 R-HSA-5685296 GATA6 binds SFTPA genes BibTex
2015-08-17 R-HSA-5688377 Defective pro-SFTPC does not translocate from ER membrane to multivesicle body BibTex
2015-08-17 R-HSA-5684868 pro-SFTPC translocates from ER membrane to multivesicle body BibTex
2015-08-17 R-HSA-5683836 SFTPC gene produces pro-SFTPC protein BibTex
2015-08-17 R-HSA-5685201 CCDC59:TTF1 binds SFTPC gene BibTex
2015-08-17 R-HSA-5683831 CCDC59 binds TTF1 BibTex
2015-08-17 R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body BibTex
2015-06-26 R-HSA-5692408 NPR2 binds NPPC BibTex
2015-06-26 R-HSA-5691512 APEH hydrolyses NAc-Ser-protein BibTex
2015-06-26 R-HSA-5696074 AGK:Mg2+ phosphorylates MAG, DAG BibTex
2015-06-26 R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA BibTex
2015-06-26 R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC BibTex
2015-06-26 R-HSA-5694583 ABHD4 hydrolyses NAPE BibTex
2015-06-26 R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters BibTex
2015-06-26 R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA BibTex
2015-06-26 R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA BibTex
2015-06-26 R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol BibTex
2015-06-26 R-HSA-5693346 CECRI deaminates Ade-Rib to Ino BibTex
2015-06-26 R-HSA-5694487 A4GNT transfers GlcNAc to core 2 mucins BibTex
2015-06-26 R-HSA-5689000 AADAC deacetylates PHEN BibTex
2015-06-26 R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA BibTex
2015-06-26 R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH BibTex
2015-06-26 R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH BibTex
2015-06-26 R-HSA-5696131 AOC1 deaminates Hist BibTex
2015-06-26 R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG BibTex
2015-06-26 R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA BibTex
2015-06-26 R-HSA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD BibTex
2015-06-26 R-HSA-5696146 AOC2 deaminates TYR BibTex
2015-06-26 R-HSA-5696183 AOC3 deaminates BZAM BibTex
2015-06-26 R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b BibTex
2015-06-26 R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 BibTex
2015-06-26 R-HSA-5696822 AKR1B15 reduces EST17b to E1 BibTex
2015-06-26 R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser BibTex
2015-06-26 R-HSA-5696839 MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF BibTex
2015-06-26 R-HSA-5694563 ABHD10 hydrolyses MPAG BibTex
2015-06-26 R-HSA-5692232 AKR1A1 oxidises BaPtDHD to BaP-7,8-dione BibTex
2015-06-26 R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH BibTex
2015-06-26 R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB BibTex
2015-06-26 R-HSA-5695964 ABHD14B hydrolyses PNPB BibTex
2015-06-26 R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite BibTex
2015-06-26 R-HSA-5696220 AS3MT transfers CH3 from AdoMet to arsenite(3-) BibTex
2015-06-26 R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite BibTex
2015-06-26 R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen BibTex
2015-06-26 R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen BibTex
2015-06-26 R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA BibTex
2015-06-26 R-HSA-6785213 LIPC dimer binds heparin BibTex
2015-06-26 R-HSA-6785178 LMF1,2 transport LIPC dimer from ER lumen to extracellular region BibTex
2015-06-26 R-HSA-6785181 LMF1,2 bind LIPC dimer BibTex
2015-06-26 R-HSA-5693001 NAT8,8B acetylate BACE1 BibTex
2015-06-26 R-HSA-5692934 BACE1 binds GGA1,2,3 BibTex
2015-06-26 R-HSA-5693086 BACE1(46-501) translocates from Golgi lumen to plasma membrane BibTex
2015-06-26 R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) BibTex
2015-06-26 R-HSA-5693081 FURIN cleaves 7K-BACE1 to 7K-BACE1(46-501) BibTex
2015-06-26 R-HSA-5693071 BACE1 translocates from ER lumen to Golgi apparatus BibTex
2015-06-26 R-HSA-6783332 APP(672-713),APP(672-711) translocate from endosome lumen to extracellular region BibTex
2015-06-26 R-HSA-5692495 BACE1 cleaves APP(18-770) to APP(18-671) and APP(672-770) BibTex
2015-06-26 R-HSA-5696448 AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG BibTex
2015-06-26 R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P BibTex
2015-06-26 R-HSA-5692437 ANG binds F-actin BibTex
2015-06-26 R-HSA-5693373 DDAH1,2 hydrolyses ADMA to DMA and L-Cit BibTex
2015-06-26 R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA BibTex
2015-06-26 R-HSA-5696004 ACSF2 ligates CoA-SH to MCFA BibTex
2015-06-26 R-HSA-5695989 ACAD11 dehydrogenates BH-CoA BibTex
2015-06-26 R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA BibTex
2015-06-26 R-HSA-5695980 ACAD10 dehydrogenates S-2MPDA-CoA BibTex
2015-06-26 R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA BibTex
2015-06-26 R-HSA-5694071 GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH BibTex
2015-06-26 R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT BibTex
2015-06-26 R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins BibTex
2015-06-26 R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA BibTex
2015-06-26 R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA BibTex
2015-06-26 R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM BibTex
2015-06-26 R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA BibTex
2015-06-26 R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe BibTex
2015-06-26 R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF BibTex
2015-06-26 R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate BibTex
2015-06-26 R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly BibTex
2015-06-26 R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL BibTex
2015-06-26 R-HSA-5693347 CRYM reduces P2C to PPCA BibTex
2015-06-26 R-HSA-6783880 PIPOX oxidises PPCA to P6C BibTex
2015-06-26 R-HSA-6783883 P6C transforms to 2AMAS BibTex
2015-06-26 R-HSA-5693153 PPM1K dephosphorylates p-BCKDH BibTex
2015-06-26 R-HSA-5693148 BCKDK phosphorylates BCKDH BibTex
2015-06-26 R-HSA-5696457 BDH2 dehydrogenates 3HBA BibTex
2015-06-26 R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA BibTex
2015-06-26 R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP BibTex
2015-06-26 R-HSA-5693783 NAALADases hydrolyse NAAG BibTex
2015-06-26 R-HSA-5691507 ASPA deacetylates NAA to acetate and L-aspartate BibTex
2015-06-26 R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist BibTex
2015-06-26 R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS BibTex
2015-06-26 R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 BibTex
2015-06-26 R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM BibTex
2015-06-26 R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM BibTex
2015-06-26 R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids BibTex
2015-06-26 R-HSA-5694082 XK:KEL:Zn2+ cleaves EDN3 BibTex
2015-06-26 R-HSA-5694462 ABHD6,12 hydrolyse 3AG BibTex
2015-06-26 R-HSA-5693925 FUT3 transfers L-fucose to Gal1,3GlcNAc BibTex
2015-06-26 R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc BibTex
2015-06-26 R-HSA-5693356 CEMIP hydrolyses HA BibTex
2015-06-26 R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP BibTex
2015-06-26 R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG BibTex
2015-06-26 R-HSA-5692941 BACE1:GGA1,2,3 translocates from plasma membrane to endosome BibTex
2015-02-22 R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA BibTex
2015-02-22 R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA BibTex
2015-02-22 R-HSA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA BibTex
2015-02-22 R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA BibTex
2015-02-22 R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA BibTex
2015-02-22 R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA BibTex
2015-02-22 R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA BibTex
2015-02-22 R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA BibTex
2015-02-22 R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA BibTex
2015-02-11 R-HSA-5333658 CLAT:AP1:CLVS bind PI(3,5)P2 BibTex
2015-02-11 R-HSA-5229111 AP4 transports APP from trans-Golgi network to endosome lumen BibTex
2015-02-11 R-HSA-5229132 AP4 binds APP BibTex
2015-02-11 R-HSA-5671702 AP1G2 binds HGS and CHMP2A BibTex
2015-02-11 R-HSA-5260201 p-AKT2 phosphorylates C2CD5 BibTex
2015-02-11 R-MMU-5263624 p-Akt2 phosphorylates C2cd5 BibTex
2015-02-11 R-HSA-5226904 AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it BibTex
2015-02-11 R-HSA-5263628 CAV3:TRIM72:DYSF binds ANXAs BibTex
2015-02-11 R-MMU-5332993 Cav3:Trim72:Dysf binds Anxas BibTex
2015-02-11 R-HSA-5263633 DYSF, CAV3 and TRIM72 bind BibTex
2015-02-11 R-HSA-5333678 CPNEs bind PL BibTex
2015-02-11 R-HSA-5334794 FABPs bind LCFAs BibTex
2015-02-11 R-HSA-5252133 ATP6AP1 binds V-ATPase BibTex
2015-02-11 R-HSA-5252001 ATP1B4 binds SNW1 BibTex
2015-02-11 R-HSA-8982617 CYGB:O2 dissociates BibTex
2015-02-11 R-HSA-5340214 CYGB binds O2 BibTex
2015-02-11 R-HSA-5340226 CYGB dioxygenates NO BibTex
2015-02-11 R-HSA-5336443 LIN7, CASK and APBA1 bind BibTex
2015-02-11 R-HSA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol BibTex
2015-02-11 R-HSA-5340320 GLTP transports GSL from plasma membrane to ER membrane BibTex
2015-02-11 R-HSA-5339535 CPTP transports C1P from plasma membrane to Golgi membrane BibTex
2015-02-11 R-HSA-5223305 ABCE1 binds RNASEL, inhibiting it BibTex
2015-02-11 R-MMU-5340404 Havcr2 binds Lgals9 BibTex
2015-02-11 R-HSA-5340385 HAVCR2 binds LGALS9 BibTex
2015-02-11 R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm BibTex
2015-02-11 R-HSA-5252079 HSP110s exchange ATP for ADP on HSP70s:ADP BibTex
2015-02-11 R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol BibTex
2015-02-11 R-HSA-5251942 Hikeshi binds HSP70s:ATP BibTex
2015-02-11 R-HSA-5252041 NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm BibTex
2015-02-11 R-HSA-5227009 ABCF1 binds EIF2 BibTex
2015-02-11 R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen BibTex
2015-02-11 R-HSA-5339524 GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol BibTex
2015-02-11 R-HSA-5250209 ARL2:GTP:ARL2BP binds SLC25A4 BibTex
2015-02-11 R-HSA-5250210 ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix BibTex
2015-02-11 R-HSA-5250217 ARL2:GTP binds ARL2BP BibTex
2015-02-11 R-HSA-5340195 NR1H4 binds DCA, CDCA, LCHA BibTex
2015-02-11 R-HSA-5336466 MRS2 transports Mg2+ from cytosol to mitochondrial matrix BibTex
2015-02-11 R-HSA-5339538 MAGT1 transports Mg2+ from extracellular region to cytosol BibTex
2015-02-11 R-HSA-5226979 ADD1:ADD2 binds DMTN BibTex
2015-02-11 R-HSA-5340124 CSN polymer binds CaPO4 BibTex
2015-02-11 R-HSA-5336453 NIPAs transport Mg2+ from extracellular region to cytosol BibTex
2015-02-11 R-MMU-5336430 Mmgt1,2 transport Mg2+ from cytosol to Golgi lumen BibTex
2015-02-11 R-HSA-5336454 MMGT1 transports Mg2+ from cytosol to Golgi lumen BibTex
2015-02-11 R-HSA-5226999 ADD1:ADD3 binds DMTN BibTex
2015-02-11 R-HSA-5252072 AZGP1 binds PIP BibTex
2015-02-11 R-HSA-5339528 TUSC3 transports Mg2+ from extracellular region to cytosol BibTex
2015-02-11 R-HSA-5226964 ANKH transports PPi from cytosol to extracellular region BibTex
2015-02-11 R-HSA-8981621 Neuroglobin:oxygen dissociates BibTex
2015-02-11 R-HSA-8981610 Neuroglobin binds oxygen BibTex
2015-02-11 R-HSA-8981622 Myoglobin:oxygen dissociates BibTex
2015-02-11 R-HSA-8981606 Myoglobin binds oxygen BibTex
2015-02-11 R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol BibTex
2015-02-11 R-CEL-5336199 cutc-1 binds Cu+ BibTex
2015-02-11 R-HSA-5334788 CUTC binds Cu+ BibTex
2015-02-11 R-HSA-5579023 NCOA2(869-1464) binds KAT6A(1-1118) BibTex
2015-02-11 R-HSA-5579018 NCOA1(868-1441) binds PAX3(1-319) BibTex
2015-02-11 R-HSA-5340251 NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 BibTex
2015-02-11 R-HSA-5246478 APOM binds retinoids BibTex
2015-01-28 R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr BibTex
2014-09-06 R-HSA-5602549 Defective TLR3 does not bind viral dsRNA BibTex
2014-09-06 R-HSA-5602624 Defective TRAF3 does not transmit the signal BibTex
2014-09-06 R-HSA-5602316 Defective MyD88 does not oligomerize within the complex of activated TLR5 BibTex
2014-09-06 R-HSA-5607838 Defective UNC93B1 does not bind TLR3 BibTex
2014-09-06 R-HSA-5228840 Defective IKBKB (IKK2) does not form a complex with IKBKA and IKBKG BibTex
2014-09-06 R-HSA-5602603 IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway BibTex
2014-09-06 R-HSA-5602472 Defective IRAK4 does not form a complex with MyD88 within the TLR5 complex BibTex
2014-09-06 R-HSA-5602606 Defective MyD88 does not bind MAL(TIRAP):TLR2/4 BibTex
2014-09-06 R-HSA-5602383 Defective MyD88 does not oligomerize within the activated TLR2/4 complex BibTex
2014-09-06 R-HSA-5262921 Defective IKBKG (NEMO) destabilizes the association of IKBKA:IKBKB:IKBKG (via TLR) BibTex
2014-09-06 R-HSA-5602672 Defective IRAK4 does not bind MyD88 within the TLR2/4 complex BibTex
2014-09-06 R-HSA-5602353 Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 BibTex
2014-09-06 R-HSA-5602712 TICAM1 deficiency blocks TLR3 pathway BibTex
2014-09-06 R-HSA-5228811 NFKBIA variant is not phosphorylated within IkBA:NF-kappaB BibTex
2014-09-06 R-HSA-5609665 CHUK, IKBKB and IKBKG form IKK complex BibTex
2014-05-22 R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids BibTex
2014-05-22 R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E BibTex
2014-05-22 R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 BibTex
2014-05-22 R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH BibTex
2014-05-22 R-HSA-5423694 AFBDHD hydrolyses non-enzymatically to AFBDHO BibTex
2014-05-22 R-HSA-5423656 AFXBO hydrolyses non-enzymatically to AFBDHD BibTex
2014-05-22 R-HSA-5423632 AFXBO binds DNA BibTex
2014-05-22 R-HSA-5423728 AFXBO translocates from cytosol to nucleoplasm BibTex
2014-05-22 R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 BibTex
2014-05-22 R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids BibTex
2014-05-22 R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C BibTex
2014-05-22 R-HSA-5490269 AFXBO-C, AFNBO-C translocate from extracellular region to cytosol BibTex
2014-05-22 R-HSA-5433067 DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG BibTex
2014-05-22 R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG BibTex
2014-05-22 R-HSA-5490230 AFXBO-SG, AFNBO-SG translocate from cytosol to extracellular region BibTex
2014-05-22 R-HSA-5423653 MGST trimers transfer GS from GSH to AFXBO and AFNBO BibTex
2014-05-22 R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO BibTex
2014-05-22 R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO BibTex
2014-02-07 R-HSA-5173005 B3GALTL transfers glucose to O-fucosyl-proteins BibTex
2014-02-07 R-HSA-5173192 POFUT2 transfers fucose to TSR domain-containing proteins BibTex
2013-11-25 R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION BibTex
2013-10-29 R-HSA-4419979 SRD5A3 reduces pPNOL to DCHOL BibTex
2013-10-29 R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL BibTex
2013-10-29 R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP BibTex
2013-05-22 R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome BibTex
2013-05-17 R-HSA-3296326 HCAR1 binds LACT BibTex
2013-05-17 R-HSA-3296244 SUCNR1 binds SUCCA BibTex
2013-05-17 R-HSA-964773 OXGR1 binds 2OG BibTex
2013-05-17 R-HSA-3296309 HCAR3 binds HCAR3 ligands BibTex
2013-05-17 R-HSA-3296304 GPR31 is a receptor for 12(S)-HETE BibTex
2013-05-16 R-HSA-3296301 CCRL2 binds CCL19 BibTex
2013-04-15 R-HSA-3323111 Cytoslic carboxylases translocate to mitochondrial matrix BibTex
2013-04-15 R-HSA-4167501 An unknown protease degrades ACACB BibTex
2013-04-15 R-HSA-4167509 Mitochondrial BTD hydrolyses BCTN BibTex
2013-04-15 R-HSA-4167511 HLCS biotinylates ACACB BibTex
2013-04-15 R-HSA-3076905 Extracellular BTD hydrolyses BCTN BibTex
2013-04-15 R-HSA-3076881 BCTN translocates to extracellular region BibTex
2013-04-15 R-HSA-3065959 An unknown protease degrades hCBXs BibTex
2013-04-15 R-HSA-3065958 An unknown protease degrades ACACA BibTex
2013-04-15 R-HSA-3165230 SLC52A1,2,3 transport RIB from extracellular region to cytosol BibTex
2013-04-15 R-HSA-3245898 TCN1 binds correnoids in the circulation BibTex
2013-04-15 R-HSA-3204311 AOX1 oxidises PXL to PDXate BibTex
2013-04-15 R-HSA-2993447 HLCS biotinylates 6x(PCCA:PCCB) BibTex
2013-04-15 R-HSA-2993802 HLCS biotinylates PC:Mn2+ BibTex
2013-04-15 R-HSA-2993799 HLCS biotinylates 6xMCCC1:6xMCCC2 BibTex
2013-04-15 R-HSA-2993814 HLCS biotinylates ACACA:Mn2+ BibTex
2013-04-15 R-HSA-2995334 COX15 transforms heme O to heme A BibTex
2013-04-15 R-HSA-2995330 COX10 transforms heme to heme O BibTex
2013-04-15 R-HSA-3149539 MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin BibTex
2013-04-15 R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl BibTex
2013-04-15 R-HSA-3159259 MMAA:MUT binds AdoCbl BibTex
2013-04-15 R-HSA-3159253 MMAB adenosylates cob(I)alamin BibTex
2013-04-15 R-HSA-3149563 MMADHC targets transport of cytosolic cob(II)alamin to mitochondria BibTex
2013-04-15 R-HSA-3149494 MMACHC:cob(II)alamin binds MMADHC BibTex
2013-04-15 R-HSA-3204318 cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR BibTex
2013-04-15 R-HSA-3095889 MMACHC dealkylates RCbl BibTex
2013-04-15 R-HSA-3149519 MMACHC decyanates CNCbl BibTex
2013-04-15 R-HSA-3000263 TCN2:RCbl is degraded to release RCbl BibTex
2013-04-15 R-HSA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome BibTex
2013-04-15 R-HSA-3000122 CD320 binds extracellular TCN2:RCbl BibTex
2013-04-15 R-HSA-3000074 TCN2 binds RCbl in the circulation BibTex
2013-04-15 R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region BibTex
2013-04-15 R-HSA-3000243 Unknown lysosomal protease degrades CBLIF:RCbl to release Cbl BibTex
2013-04-15 R-HSA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome BibTex
2013-04-15 R-HSA-3000103 CUBN:AMN binds CBLIF:RCbl BibTex
2013-04-15 R-HSA-3000120 CBLIF binds RCbl BibTex
2013-04-15 R-HSA-3132753 Pancreatic proteases degrade TCN1:RCbl BibTex
2013-04-15 R-HSA-3132759 TCN1 binds RCbl BibTex
2013-02-13 R-NUL-3139045 AKT phosphorylates Bad BibTex
2013-02-11 R-HSA-3134821 DNA-PK binds microbial dsDNA BibTex
2013-02-11 R-HSA-3249370 p-S407,Y641-STAT6 dimer migrates to the nucleus BibTex
2013-02-11 R-HSA-3249372 p-S407,Y641-STAT6 is dimerized BibTex
2013-02-11 R-HSA-3249379 p-S407-STAT6 is phosphorylated at Tyr641 BibTex
2013-02-11 R-HSA-3249371 TBK1 phosphorylates STAT6 at Ser407 BibTex
2013-02-11 R-HSA-3249390 TBK1 is phosphorylated within STING:TBK1:STAT6 complex BibTex
2013-02-11 R-HSA-3249378 STING recruits TBK1 and STAT6 BibTex
2013-02-11 R-HSA-3134883 Beta-catenin enhances association of IRF3 with CBP/p300 BibTex
2013-02-11 R-HSA-3134914 Beta-catenin migrates to the nucleus BibTex
2013-02-11 R-HSA-3134904 Phosphorylation of beta-catenin at Ser552 BibTex
2013-02-11 R-HSA-3134901 LRR FLII-interacting protein 1 associates with beta-catenin BibTex
2013-02-11 R-HSA-3134896 LRR FLII-interacting protein 1 binds dsDNA BibTex
2013-02-11 R-HSA-3245943 Viral DNA cleavage by TREX1 BibTex
2013-02-11 R-HSA-3244605 TREX1 binds retroviral-derived DNA BibTex
2013-02-11 R-HSA-3134946 DDX41 ubiquitination by TRIM21 BibTex
2013-02-11 R-HSA-3249386 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 BibTex
2013-02-11 R-HSA-8948703 NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 BibTex
2013-02-11 R-HSA-8948709 DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 BibTex
2013-02-11 R-HSA-3249392 NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 BibTex
2013-02-11 R-HSA-3204303 MRE11 binds cytosolic DNA BibTex
2013-02-11 R-HSA-3134953 DHX36 or DHX9 binds MyD88 BibTex
2013-02-11 R-HSA-3134962 DHX36 binds DNA BibTex
2013-02-11 R-HSA-3134954 DHX9 binds DNA BibTex
2013-02-11 R-HSA-3134822 DDX41 binds viral dsDNA BibTex
2013-02-11 R-HSA-9013869 DDX41 binds bacterial c-di-AMP, c-di-GMP BibTex
2013-02-11 R-HSA-3244643 STING binds cyclic GMP-AMP BibTex
2013-02-11 R-HSA-3134800 STING dimerization BibTex
2013-02-11 R-HSA-3134804 STING ubiquitination by TRIM32 or TRIM56 BibTex
2013-02-11 R-HSA-1964496 STING binds TRIM32 or TRIM56 BibTex
2013-02-11 R-HSA-3244614 cGAS produces cyclic GMP-AMP BibTex
2013-02-11 R-HSA-3244647 cGAS binds cytosolic DNA BibTex
2013-02-11 R-HSA-1964482 RNA polymerase III transcribes microbial dsDNA to dsRNA BibTex
2012-11-30 R-HSA-3296233 T2Rs bind bitter-tasting compounds BibTex
2012-11-07 R-GGA-2132047 Spontaneous hydrolysis of an internal thioester bond in complement factor C3 BibTex
2012-11-07 R-GGA-2132104 Complement factor B binds to the hydrolyzed form of C3 BibTex
2012-11-07 R-GGA-2132100 Fluid-phase proteolytic cleavage of factor B BibTex
2012-11-07 R-GGA-2132064 Antigen bound antibody interacts with C1complement complex BibTex
2012-11-07 R-GGA-2132122 Activation of C1r within the C1complement complex BibTex
2012-11-07 R-GGA-2132065 C1r activates C1s component within C1 complement complex BibTex
2012-11-07 R-GGA-2132187 MBL or ficolin binds an oligosaccharide pattern on the target cell surface BibTex
2012-11-07 R-GGA-2132206 MASPs activation BibTex
2012-11-07 R-GGA-2132233 Proteolytic cleavage of complement factor C4 BibTex
2012-11-07 R-GGA-2132248 C4b binds to target cell surface BibTex
2012-11-07 R-GGA-2132096 Formation of C4b:factor B complex BibTex
2012-11-07 R-GGA-2132222 Cleavage of factor B to form classical C3 convertase BibTex
2012-11-07 R-GGA-2173323 Cleavage of C3 by fluid-phase C3i:factor B BibTex
2012-11-07 R-GGA-2132210 C3b fragment binds to the target cell surface BibTex
2012-11-07 R-GGA-2132061 Complement factor B binds to surface-bound C3b fragment BibTex
2012-11-07 R-GGA-2132074 Cleavage of surface-bound factor B BibTex
2012-11-07 R-GGA-2132085 Cleavage of C3 by surface-bound C3 convertases BibTex
2012-11-07 R-GGA-2173317 C3a anaphylatoxin binds C3a receptor BibTex
2012-11-07 R-GGA-2132264 Formation of alternate C5 convertase BibTex
2012-11-07 R-GGA-2132269 Formation of classical C5 convertase BibTex
2012-11-07 R-GGA-2132278 Cleavage of C5 by C5 convertases BibTex
2012-11-07 R-GGA-2173318 C5a anaphylatoxin binds C5a receptor BibTex
2012-11-07 R-GGA-2132201 Opsonization with C3b or C4b BibTex
2012-11-07 R-GGA-2859050 Hydrolysis of C4b BibTex
2012-11-07 R-GGA-2132261 Complement factor H binds to C3b BibTex
2012-11-07 R-GGA-2132276 Complement factor I inactivates C3b BibTex
2012-11-07 R-GGA-2530565 iC3b proteolysis BibTex
2012-11-07 R-GGA-2132277 Complement factor H binds to surface-bound C3b BibTex
2012-11-07 R-GGA-2132271 Factor H displaces Bb in Cb:Bb complex BibTex
2012-11-07 R-GGA-2132260 Complement factor I inactivates surface-bound C3b BibTex
2012-11-07 R-GGA-2132284 Formation of C5b:C6 BibTex
2012-11-07 R-GGA-2132060 Formation of C5b:C6:C7 BibTex
2012-11-07 R-GGA-2132136 Vitronectin binds to C5b-C7 complex BibTex
2012-11-07 R-GGA-2530573 CREG(CR1L) binds to surface-bound C3 convertases BibTex
2012-11-07 R-GGA-2132133 C5b:C6:C7 inserts into the target cell membrane BibTex
2012-11-07 R-GGA-2132094 C8 binds to C5b:C6:C7 complement complex BibTex
2012-11-07 R-GGA-2132247 CD59 binds C5b:C6:C7:C8 BibTex
2012-11-07 R-GGA-2132088 Vitronectin prevents C9 polymerization BibTex
2012-11-07 R-GGA-2530591 CREG (CR1L) causes dissociation of C3 convertases BibTex
2012-11-07 R-GGA-2132283 Factor H binds to host cell surface BibTex
2012-11-07 R-GGA-2530584 CREM (CREMP) binds to surface-bound C3b or C4b BibTex
2012-11-07 R-GGA-2132221 C5b:C6:C7:C8 and C9 bind to form membrane attack complex (MAC) BibTex
2012-07-18 R-HSA-2395992 p-T,4S-IRF3 is dimerized BibTex
2012-07-18 R-HSA-2396007 IRF3 is phosphorylated by TBK1 BibTex
2012-07-18 R-HSA-2396002 TBK1 is phosphorylated within STING:TBK1:IRF3 complex BibTex
2012-07-18 R-HSA-1834939 STING recruits TBK1 and IRF3 BibTex
2012-07-18 R-HSA-2396009 STING binds c-di-GMP BibTex
2012-07-18 R-HSA-1834951 IFI16 binds cytosolic dsDNA BibTex
2012-05-25 R-HSA-9013974 Auto-ubiquitination of TRAF3 within activated TLR3 complex BibTex
2012-05-25 R-HSA-9013992 TRAF3 binds to TRIF:activated TLR3 complex BibTex
2012-05-25 R-HSA-2201341 Endocytosis of TRAM (TICAM2) BibTex
2012-05-25 R-HSA-2201293 Endocytosis of TLR4:LY96:LPS:CD14 BibTex
2012-05-25 R-HSA-2213017 Auto-ubiquitination of TRAF3 BibTex
2012-05-25 R-HSA-2201338 TRAF3 binds TICAM1:activated TLR4 complex BibTex
2012-05-25 R-HSA-2201322 TIRAP is phosphorylated by BTK BibTex
2012-05-25 R-HSA-2559414 Activated TLR2/4:TIRAP interacts with BTK BibTex
2012-05-25 R-HSA-2201316 Activated TLR2/4 interacts with MAL (TIRAP) BibTex
2012-05-15 R-HSA-2248891 M6PR transports activated ARSA to the lysosome BibTex
2012-05-14 R-HSA-1614336 SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases BibTex
2012-05-14 R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases BibTex
2012-04-23 R-HSA-2179407 SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) BibTex
2012-04-23 R-HSA-2179415 GRB2:SOS1 binds to HBEGF:p-Y-EGFR BibTex
2012-04-23 R-HSA-2179387 Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor BibTex
2012-04-23 R-HSA-2179402 Active MMP3 can cleave pro-HBEGF to form active HBEGF BibTex
2012-04-23 R-MMU-2203911 Active Mmp3 can cleave pro-Hbegf to form active Hbegf BibTex
2012-04-23 R-HSA-2179413 Activated PKC-alpha activate MMP3 BibTex
2012-04-23 R-HSA-870269 Gastrin binds to CCK-B receptor BibTex
2012-03-28 R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments BibTex
2012-03-28 R-HSA-2162229 The single sugars GlcA and GlcNAc translocate from the lysosome to the cytosol BibTex
2012-03-28 R-HSA-2162226 GUSB tetramer hydrolyses GlcA-?1,3-GlcNAc BibTex
2012-03-28 R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments BibTex
2012-03-28 R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 BibTex
2012-03-28 R-HSA-2160874 HYAL1 hydrolyses (HA)50 BibTex
2012-03-28 R-HSA-2160906 20kDa HA fragments are translocated to lysosomes BibTex
2012-03-28 R-HSA-2160892 Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments BibTex
2012-03-28 R-HSA-2160884 HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ BibTex
2012-03-28 R-HSA-2160915 Receptor-mediated uptake of HA BibTex
2012-03-28 R-HSA-2142859 Growing HA is extruded from the cell by ABCC5 BibTex
2012-03-28 R-HSA-2160851 HAS1,2,3 mediate the polymerization of HA BibTex
2012-03-28 R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS BibTex
2012-03-28 R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS BibTex
2012-03-28 R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS BibTex
2012-03-28 R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) BibTex
2012-03-28 R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains BibTex
2012-03-28 R-HSA-1606789 ARSB hydrolyses DS BibTex
2012-03-28 R-HSA-1793176 DS is cleaved from its proteoglycan BibTex
2012-03-28 R-HSA-1793207 ARSB hydrolyses C4S/C6S chains BibTex
2012-03-28 R-HSA-2065233 CS is cleaved from its proteoglycan BibTex
2012-03-28 R-HSA-2022056 DSPG and CSPG translocate to the lysosome for degradation BibTex
2012-03-28 R-HSA-2022911 CSPG is secreted BibTex
2012-03-28 R-HSA-2018659 Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 BibTex
2012-03-28 R-HSA-2018682 CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains BibTex
2012-03-28 R-HSA-9632033 CHSY1 transfers GalNAc to chondroitin BibTex
2012-03-28 R-HSA-2022065 DSPGs are secreted BibTex
2012-03-28 R-HSA-2022063 CHST14 transfers SO4(2-) to GalNAc in dermatan or DS BibTex
2012-03-28 R-HSA-2022061 Dermatan sulfate can be further sulfated on position 2 of iduronate BibTex
2012-03-28 R-HSA-2022052 Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) BibTex
2012-03-28 R-HSA-1971483 Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 BibTex
2012-03-28 R-HSA-1971487 CHPF,CHSY3 transfer GalNAc to chondroitin BibTex
2012-03-28 R-HSA-1971491 CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin BibTex
2012-03-28 R-HSA-9632034 CHSY1 transfers GlcA to chondroitin BibTex
2012-03-28 R-HSA-1971482 The addition of GalNAc to the terminal glucuronate residue forms chondroitin BibTex
2012-03-28 R-HSA-1678694 Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans BibTex
2012-03-28 R-HSA-2090079 GLB1 hydrolyses linker chain(2) BibTex
2012-03-28 R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor BibTex
2012-03-28 R-HSA-2090038 NAGLU hydrolyses heparan chain(2) BibTex
2012-03-28 R-HSA-2046239 Extracellular KSPG translocates to the lysosome for degradation BibTex
2012-03-28 R-HSA-1793217 Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase BibTex
2012-03-28 R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate BibTex
2012-03-28 R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan BibTex
2012-03-28 R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate BibTex
2012-03-28 R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate BibTex
2012-03-28 R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate BibTex
2012-03-28 R-HSA-2025723 B4GALTs transfer Gal to the N-glycan precursor BibTex
2012-03-28 R-HSA-2025724 B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG BibTex
2012-03-28 R-HSA-2046265 B4GALTs transfer Gal to the keratan chain BibTex
2012-03-28 R-HSA-2046298 B4GALTs transfer Gal to a branch of keratan BibTex
2012-03-28 R-HSA-2046285 The keratan chain can be capped by N-acetylneuraminic acid BibTex
2012-03-28 R-HSA-2046222 CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG BibTex
2012-03-28 R-HSA-2046175 Further sulfation on galactose residues produces KSPG BibTex
2012-03-28 R-HSA-2046180 KSPG is secreted from the cell BibTex
2012-03-28 R-HSA-1878002 XYLTs transfer Xyl to core protein BibTex
2012-03-28 R-HSA-1889981 B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker BibTex
2012-03-28 R-HSA-1889978 B3GALT6 transfers Gal to the tetrasaccharide linker BibTex
2012-03-28 R-HSA-9638064 B3GAT3 dimer transfers GlcA to tetrasaccharide linker BibTex
2012-03-28 R-HSA-1889955 B3GAT dimers transfer GlcA to tetrasaccharide linker BibTex
2012-03-28 R-HSA-2022919 EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue BibTex
2012-03-28 R-HSA-2022856 EXT1:EXT2 transfers GlcNAc to heparan BibTex
2012-03-28 R-HSA-2022851 EXT1:EXT2 transfer GlcNAc to the heparan chain BibTex
2012-03-28 R-HSA-2076392 EXT1:EXT2 transfers GlcA to heparan BibTex
2012-03-28 R-HSA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan BibTex
2012-03-28 R-HSA-2022860 NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) BibTex
2012-03-28 R-MMU-2024090 Glce epimerises GlcA to IdoA BibTex
2012-03-28 R-HSA-2024100 GLCE epimerises GlcA to IdoA BibTex
2012-03-28 R-HSA-2076508 HS2ST1 sulfates IdoA at C2 in heparan sulfate BibTex
2012-03-28 R-HSA-2076383 HS3ST1 sulfates GlcN at C3 in heparan sulfate BibTex
2012-03-28 R-HSA-2076611 HS3STs sulfate GlcN at C3 in heparan sulfate BibTex
2012-03-28 R-HSA-2076371 GLCE epimerises more GlcA to IdoA as sulfate content rises BibTex
2012-03-28 R-HSA-2076419 HS6STs sulfate GlcN at C6 in heparan sulfate/heparin BibTex
2012-03-28 R-HSA-2024108 Some HSPGs are secreted to the plasma membrane BibTex
2012-03-28 R-HSA-2024084 HS-GAGs translocate to the lysosome for degradation BibTex
2012-03-28 R-HSA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) BibTex
2012-03-28 R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) BibTex
2012-03-28 R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) BibTex
2012-03-28 R-HSA-1678660 HGSNAT oligomer acetylates Heparan sulfate chain(3) BibTex
2012-03-28 R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) BibTex
2012-03-28 R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) BibTex
2012-03-28 R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) BibTex
2012-03-28 R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) BibTex
2012-03-28 R-HSA-2090085 HGSNAT oligomer acetylates Heparan chain(1) BibTex
2011-12-08 R-HSA-9604480 NFkB complex translocates from the cytosol to the nucleus BibTex
2011-12-08 R-HSA-2032396 Dimerized phospho-IRF3 migrates to the nucleus BibTex
2011-12-08 R-HSA-1606327 Phosphorylation and release of IRF3 BibTex
2011-12-08 R-HSA-1606345 Recruitment of IRF3 to activated ZBP1:TBK1 BibTex
2011-12-08 R-MMU-1810458 Recruitment of Irf3 to activated Dai:Tbk1 BibTex
2011-12-08 R-HSA-1606324 Recruitment TBK1 to dsDNA:ZBP1 followed by its activation BibTex
2011-12-08 R-MMU-1810473 Recruitment Tbk1 to dsDNA:Dai followed by its activation BibTex
2011-12-08 R-HSA-168166 NF-kappa-B complex is transported from cytosol to nucleus BibTex
2011-12-08 R-HSA-168140 Active IKK Complex phosphorylates NF-kappa-B inhibitor BibTex
2011-12-08 R-HSA-168910 RIP1 facilitates IKK complex phosphorylation BibTex
2011-12-08 R-HSA-1810457 ZBP1(DAI) recruits RIP1 and RIP3 BibTex
2011-12-08 R-HSA-1591234 ZBP1 binds cytosolic DNA BibTex
2011-12-08 R-HSA-9773803 Active IKBKB phosphorylates NF-kappa-B inhibitor BibTex
2011-11-02 R-HSA-1268025 SAM50 complex inserts proteins into mitochondrial outer membrane BibTex
2011-11-02 R-SCE-1252261 SAM50 complex inserts proteins into outer membrane BibTex
2011-11-02 R-HSA-1299482 TIMM23 SORT inserts proteins into inner membrane BibTex
2011-11-02 R-SCE-1252249 TIM23 SORT complex inserts proteins into inner membrane BibTex
2011-11-02 R-HSA-1307802 MIA40:ERV1 (CHCHD4:GFER) oxidizes cysteine residues to cystine disulfide bonds BibTex
2011-11-02 R-SCE-1252260 MIA40:ERV1 oxidizes cysteine residues to cystine disulfide bonds BibTex
2011-11-02 R-HSA-1307803 TIMM22 inserts proteins into inner membrane BibTex
2011-11-02 R-SCE-1252258 TIM22 complex inserts proteins into inner membrane BibTex
2011-11-02 R-HSA-1299484 TIMM8:TIMM13 chaperones hydrophobic proteins BibTex
2011-11-02 R-SCE-1252262 TIM8:TIM13 chaperones hydrophobic proteins BibTex
2011-11-02 R-HSA-1955380 TIMM9:TIMM10 transfers proteins to TIMM22 BibTex
2011-11-02 R-HSA-1299481 TIMM9:TIMM10 binds hydrophobic proteins BibTex
2011-11-02 R-SCE-1252259 TIM9:TIM10 binds hydrophobic proteins BibTex
2011-11-02 R-HSA-1299476 MPP cleaves targeting peptide (presequence) of inner membrane precursors BibTex
2011-11-02 R-SCE-1268019 MPP hydrolyzes presequence of inner membrane precursors BibTex
2011-11-02 R-HSA-1299487 Precursor proteins enter TIMM23 SORT BibTex
2011-11-02 R-SCE-1268015 Precursor proteins enter TIM23 SORT complex BibTex
2011-11-02 R-HSA-1299475 TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix BibTex
2011-11-02 R-SCE-1252253 TIM23 PAM complex translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix BibTex
2011-11-02 R-HSA-1299478 MPP cleaves targeting peptide (presequence) of matrix precursors BibTex
2011-11-02 R-SCE-1268017 MPP hydrolyzes presequence of matrix precursors BibTex
2011-11-02 R-HSA-1299480 Precursor proteins enter TIMM23 PAM BibTex
2011-11-02 R-SCE-1268014 Precursor proteins enter TIM23 PAM complex BibTex
2011-11-02 R-HSA-1268022 TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space BibTex
2011-11-02 R-SCE-1252255 TOM40:TOM70 complex translocates proteins from the cytosol to the mitochondrial intermembrane space BibTex
2011-10-26 R-HSA-977301 Histidine is decarboxylated to histamine BibTex
2011-10-26 R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser BibTex
2011-10-26 R-HSA-977333 PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA BibTex
2011-10-26 R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) BibTex
2011-10-26 R-HSA-977348 PHGDH tetramer dehydrogenates 3PG BibTex
2011-10-13 R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S BibTex
2011-10-13 R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S BibTex
2011-10-13 R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione BibTex
2011-10-13 R-HSA-1614618 Persulfide sulfur is transferred onto sulfite BibTex
2011-10-13 R-HSA-1614591 Excess cysteine yields lanthionine and H2S BibTex
2011-10-13 R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU BibTex
2011-10-13 R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine BibTex
2011-10-13 R-RNO-1655440 PXLP-K305-Csad decarboxylates 3-sulfinoalanine to hypotaurine BibTex
2011-10-13 R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine BibTex
2011-10-13 R-HSA-1614654 BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY BibTex
2011-10-13 R-HSA-1614546 Sulfate is exported to the cytosol in exchange for dicarboxylate BibTex
2011-10-13 R-HSA-1614544 Sulfite is oxidized to sulfate BibTex
2011-10-13 R-HSA-1614605 Persulfide sulfur is dioxygenated BibTex
2011-10-13 R-HSA-1614665 SQR oxidizes sulfide to bound persulfide BibTex
2011-10-13 R-HSA-1614614 Cysteine is degraded to serine and H2S BibTex
2011-10-13 R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine BibTex
2011-10-13 R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine BibTex
2011-08-23 R-HSA-1497866 Peroxynitrite can oxidise BH4 to the BH3 radical BibTex
2011-08-23 R-HSA-1474158 GCHFR binds to GCH1 and negatively regulates its activity BibTex
2011-08-23 R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR BibTex
2011-08-23 R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr BibTex
2011-08-23 R-HSA-1497878 Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) BibTex
2011-08-23 R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide BibTex
2011-08-23 R-HSA-1497796 BH2 binding can lead to eNOS uncoupling BibTex
2011-08-23 R-HSA-1497863 The BH3 radical can decay to dihydrobiopterin (BH2) BibTex
2011-08-23 R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle BibTex
2011-08-23 R-HSA-1497855 Ascorbate can reduce the BH3 radical back to BH4 BibTex
2011-08-23 R-HSA-1475414 PTHP is reduced to BH4 by sepiapterin reductase (SPR) BibTex
2011-08-23 R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP BibTex
2011-08-23 R-HSA-1475422 PTPS is phosphorylated by cGMP-dependant protein kinase II BibTex
2011-08-23 R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate BibTex
2011-08-23 R-HSA-1497883 Ferrous iron reduces the BH3 radical back to BH4 BibTex
2011-08-23 R-HSA-1497853 Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II BibTex
2011-08-23 R-HSA-1497869 Salvage - Sepiapterin is reduced to BH2 BibTex
2011-08-23 R-HSA-1497784 The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle BibTex
2011-08-23 R-HSA-1467466 ABCA4 mediates atRAL transport BibTex
2011-08-23 R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix BibTex
2011-08-23 R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport BibTex
2011-08-23 R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region BibTex
2011-08-23 R-HSA-1454916 The ABCC family mediates organic anion transport BibTex
2011-08-23 R-HSA-1454928 ABCG4 may mediate cholesterol efflux BibTex
2011-08-23 R-HSA-1369028 ABCAs mediate lipid efflux BibTex
2011-08-23 R-HSA-1369052 ABCAs mediate lipid influx BibTex
2011-08-23 R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix BibTex
2011-05-23 R-HSA-1247939 CysGly translocates from extracellular region to cytosol BibTex
2011-05-23 R-HSA-8943279 GGT dimers hydrolyse GSH BibTex
2011-05-23 R-HSA-1247915 GSH translocates from cytosol to extracellular region BibTex
2011-05-23 R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly BibTex
2011-05-23 R-HSA-1247922 GGCT transforms gGluCys to OPRO BibTex
2011-05-23 R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu BibTex
2011-05-23 R-HSA-1237102 Transamination of MOB to methionine BibTex
2011-05-23 R-HSA-1237119 Acireductone is oxidized to MOB BibTex
2011-05-23 R-HSA-1237129 Acireductone is created BibTex
2011-05-23 R-HSA-1237140 Dehydration of methylthio-ribulose-P BibTex
2011-05-23 R-HSA-1299507 Methylthio-ribulose-P = Methylthio-ribose-P BibTex
2011-05-23 R-HSA-1237096 Methylthio-ribose-P = Methylthio-ribulose-P BibTex
2011-05-23 R-HSA-1237160 MTA is cleaved and phosphorylated BibTex
2010-12-06 R-GGA-1008270 Activated TAK1 leaves endosome membrane BibTex
2010-12-06 R-GGA-994000 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation BibTex
2010-12-06 R-GGA-573296 Activated TRAF6 recruits TAK1 kinase complex upon TLR7 or TLR21 stimulation BibTex
2010-12-06 R-GGA-573294 Activated TRAF6 synthesizes free K63 linked pUb chains. BibTex
2010-12-06 R-GGA-571318 Autoubiquitination of oligoTRAF6 bound to p-IRAK2 BibTex
2010-12-06 R-GGA-573297 TRAF6 binding to IRAK2 stimulates its oligomerizartion upon TLR7 or TLR21 stimulation BibTex
2010-12-06 R-GGA-571327 IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex BibTex
2010-12-06 R-GGA-571324 IRAK2 binds to p-IRAK4:MyD88:activated TLR7 or 21 complex BibTex
2010-12-06 R-GGA-571316 Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. BibTex
2010-12-06 R-GGA-451461 IRAK4 binds to the activated TLR7 or 21 BibTex
2010-12-06 R-GGA-451439 Activated TLR7 or 21 recruits MyD88 BibTex
2010-12-06 R-GGA-451506 TLR21homodimer binds to DNA BibTex
2010-12-06 R-GGA-977239 Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 BibTex
2010-12-06 R-GGA-977237 IRAK2 binds to IRAK4 associated with activated TLR : MyD88 complex BibTex
2010-12-06 R-GGA-977250 Autophosphorylation of IRAK4 bound to activated TLR5 or 15 BibTex
2010-12-06 R-GGA-451481 TLR7 binds to recognized ligands BibTex
2010-12-06 R-GGA-532630 p-IRAK2- TRAF6 dissociates from the activated TRL7 or 21 BibTex
2010-12-06 R-GGA-532632 TRAF6 binds to p-IRAK2 complexed with activated TLR7 or TLR21 BibTex
2010-12-06 R-GGA-434130 IRAK4 binds to activated TLR5 or 15. BibTex
2010-12-06 R-GGA-977238 Activated TLR5/TLR15 homodimer recruits MyD88 adaptor BibTex
2010-12-06 R-GGA-451474 Bacterial Flagellin binds TLR5 homodimer BibTex
2010-12-06 R-GGA-451511 TLR15 binds to recognized ligand BibTex
2010-11-30 R-HSA-981713 C4b binds to cell surface BibTex
2010-11-30 R-HSA-981539 C3b binds to cell surface BibTex
2010-11-09 R-HSA-975608 LRAT esterifies RBP2:atROL and FACYLs to atREs BibTex
2010-11-09 R-HSA-975633 atROL binds to RBP2 BibTex
2010-11-09 R-HSA-975594 PLB1 hydrolyses RPALM to atROL BibTex
2010-11-09 R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL BibTex
2010-11-09 R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL BibTex
2010-11-09 R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM BibTex
2010-11-08 R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP BibTex
2010-11-08 R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP BibTex
2010-11-08 R-HSA-964962 2xPDKX:2xZn2+ phosphorylates PDX BibTex
2010-11-08 R-HSA-964970 2xPDXK:2xZn2+ phosphorylates PXL BibTex
2010-11-08 R-HSA-964958 2xPDXK:2xZn2+ phosphorylates PXA BibTex
2010-11-05 R-HSA-947499 Exchange of oxygen with sulfur in MoCo BibTex
2010-11-05 R-HSA-947531 Molybdenum ion transfer onto molybdopterin BibTex
2010-11-05 R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z BibTex
2010-11-05 R-HSA-947538 Transfer of sulfur from MOCS3-S-S onto MOCS2A BibTex
2010-11-05 R-HSA-947514 PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 BibTex
2010-11-05 R-HSA-947535 Cyclisation of GTP to precursor Z BibTex
2010-11-05 R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP BibTex
2010-11-05 R-HSA-997381 TDPK phosphorylates ThDP to ThTP BibTex
2010-11-05 R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region BibTex
2010-11-05 R-HSA-917870 SLC46A1 transports hemes from extracellular region to cytosol BibTex
2010-11-05 R-HSA-917936 MCOLN1 transports Fe2+ from endosome lumen to cytosol BibTex
2010-11-05 R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ BibTex
2010-11-05 R-HSA-917841 Acidification of Tf:TfR1 containing endosome BibTex
2010-11-05 R-HSA-917807 holoTF:TFRC dimer translocates from plasma membrane to endosome membrane BibTex
2010-11-05 R-HSA-917987 TFRC dimer binds 2xholoTF BibTex
2010-11-05 R-HSA-917839 apo-Transferrin dissociates from the receptor complex BibTex
2010-11-05 R-HSA-917814 apoTF:TFRC dimer translocates from endosome membrane to plasma membrane BibTex
2010-11-05 R-HSA-917835 Fe3+ dissociates from holoTF:TFRC dimer BibTex
2010-11-05 R-HSA-917888 apoTF binds 2Fe3+ to form holoTF BibTex
2010-11-05 R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ BibTex
2010-11-05 R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ BibTex
2010-11-05 R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ BibTex
2010-11-05 R-HSA-917892 FLVCR1-1 transports heme from cytosol to extracellular region BibTex
2010-10-16 R-GGA-921145 Activated chicken TAK1 dissociates from the activated TLR3 complex BibTex
2010-10-16 R-GGA-434047 phosphorylation of IRAK2 by activated IRAK4 BibTex
2010-10-16 R-GGA-433864 IRAK2 binds to the IRAK4 accociated with the complex of the activated TLR : TIRAP : MyD88 BibTex
2010-10-16 R-GGA-451508 Nuclear translocation of phospho ERK2 dimer BibTex
2010-10-16 R-GGA-451535 Dimerization of activated ERK2 BibTex
2010-10-16 R-GGA-451505 Dissociation of phospho ERK2 :phospho MEK2 complex BibTex
2010-10-16 R-GGA-451516 activated MEK2 phosphorylates ERK2 BibTex
2010-10-16 R-GGA-451482 activated MEK2 binds ERK2 BibTex
2010-10-16 R-GGA-434018 Autophosphorylation of chicken IRAK4 BibTex
2010-10-16 R-GGA-434073 IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88 BibTex
2010-10-16 R-GGA-433961 Activated TLR homo- or heterodimer recruits adaptors TIRAP(or MAL) and MyD88 BibTex
2010-10-16 R-GGA-517850 TLR2-1 : TLR1-2 heterodimer binds to its ligand BibTex
2010-10-16 R-GGA-517846 TLR2-1 :TLR1-1 binds to triacyl lipopeptide BibTex
2010-10-16 R-GGA-434058 LPS binding to Toll like receptor 4 results in dimerization of the TLR4 associated with LY96 BibTex
2010-10-16 R-GGA-434003 LPS binding to CD14 co-receptor BibTex
2010-10-16 R-GGA-433940 Association of LBP with bacterial LPS BibTex
2010-10-16 R-GGA-451447 Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 BibTex
2010-10-16 R-GGA-451463 pUb_TRAF6 pIRAK2 recruits TAK1 kinase complex BibTex
2010-10-16 R-GGA-451470 Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex p-IRAK2:pUb_oligo TRAF6 BibTex
2010-10-16 R-GGA-451450 Auto ubiquitination of oligo TRAF6 bound to p-IRAK2 BibTex
2010-10-16 R-GGA-451466 TRAF6 binding to activated IRAK2 stimulates its oligomerization BibTex
2010-10-16 R-GGA-434084 p-IRAK2- TRAF6 dissociates from the activated chTLR complex BibTex
2010-10-16 R-GGA-434053 TRAF6 binds to p-IRAK2 complexed with activated TLR BibTex
2010-05-26 R-HSA-444773 EGF-TM7 receptors bind chondroitin sulphate BibTex
2010-05-26 R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) BibTex
2010-05-26 R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) BibTex
2010-05-26 R-NUL-8982704 PKC (cow) binds G alpha z (rat) BibTex
2010-05-26 R-HSA-825631 Glucagon:GCGR mediates GTP-GDP exchange BibTex
2010-05-23 R-GGA-433967 Dimerized Phospho-IRF3 is Transported To The Nucleus BibTex
2010-05-23 R-GGA-434027 Dimerization of Phospho-IRF3 BibTex
2010-05-23 R-GGA-433786 Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 BibTex
2010-05-23 R-GGA-433826 Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. BibTex
2010-05-23 R-GGA-433804 IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex BibTex
2010-05-23 R-GGA-434030 TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex BibTex
2010-05-23 R-GGA-442862 Nuclear export of p38 MAPK mediated by its substrate MAPKAPK2 or 3 BibTex
2010-05-23 R-GGA-442913 Active p38 MAPK phosphorylates MAPKAPK2 or 3 BibTex
2010-05-23 R-GGA-438019 activated chicken MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 BibTex
2010-05-23 R-GGA-442938 activated MAPK3/MAPK6 migrates to nucleus BibTex
2010-05-23 R-GGA-437984 Phosphorylation of MKK3/MKK6 by activated TAK1 BibTex
2010-05-23 R-GGA-438026 Activation and dimerization of c-JUN in the nucleus BibTex
2010-05-23 R-GGA-437995 Activated JNK migrates to the nucleoplasm BibTex
2010-05-23 R-GGA-438005 MKK4 phosphorylates JNK BibTex
2010-05-23 R-GGA-437999 Phosphorylation of MKK4 by activated TAK1 BibTex
2010-05-23 R-GGA-433823 Released NFkB complex migrates to the nucleus and turns on transcription BibTex
2010-05-23 R-GGA-433986 activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB BibTex
2010-05-23 R-GGA-433955 Phosphorylation of IKKs complex by activated TAK1 BibTex
2010-05-23 R-GGA-433957 Activation of recruited TAK1 BibTex
2010-05-23 R-GGA-433950 TRAF6 recruits TAK1 kinase complex BibTex
2010-05-23 R-GGA-433936 Activated chicken TRAF6 synthesizes free K63bound poly_Ub chains within the complex dsRNA :TLR3 :TICAM1 BibTex
2010-05-23 R-GGA-433981 Auto ubiquitination of the TRAF6 within the complex viral dsRNA:TLR3:TICAM1:TRAF6 BibTex
2010-05-23 R-GGA-433808 viral dsRNA: TLR3: TICAM1 recruits TRAF6 BibTex
2010-05-23 R-GGA-433845 chicken RIP1 facilitates IKKs complex activation BibTex
2010-05-23 R-GGA-434097 viral dsRNA:TRL3:TICAM1 activates RIP1 BibTex
2010-05-23 R-GGA-433815 viral dsRNA : TRL3 recruits TICAM1 BibTex
2010-05-23 R-GGA-434004 viral dsRNA binds the toll-like receptor 3 (TLR3) BibTex
2010-05-22 R-HSA-751013 Inactive G alpha (s) reassociates with G beta:gamma BibTex
2010-05-22 R-HSA-750993 Inactive G alpha (q) reassociates with G beta:gamma BibTex
2010-05-22 R-HSA-751039 Inactive G alpha (12/13) reassociates with G beta:gamma BibTex
2010-05-22 R-HSA-751001 Inactive G alpha (i) reassociates with G beta:gamma BibTex
2010-05-22 R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) BibTex
2010-05-22 R-HSA-751040 PKC phosphorylates G alpha (z) BibTex
2010-05-22 R-HSA-750988 Inactive G alpha (z) reassociates with G beta:gamma BibTex
2010-05-22 R-HSA-8982703 PKC binds active G alpha (z) BibTex
2010-05-22 R-HSA-744886 The Ligand:GPCR:Gs complex dissociates BibTex
2010-05-22 R-HSA-744887 Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs BibTex
2010-05-22 R-HSA-751024 The Ligand:GPCR:Gz complex dissociates BibTex
2010-05-22 R-HSA-749453 Liganded Gz-activating GPCR acts as a GEF for Gz BibTex
2010-05-22 R-HSA-749446 Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz BibTex
2010-05-22 R-HSA-749452 The Ligand:GPCR:Gq complex dissociates BibTex
2010-05-22 R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq BibTex
2010-05-22 R-HSA-749454 The Ligand:GPCR:Gi complex dissociates BibTex
2010-05-22 R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi BibTex
2010-05-22 R-HSA-751019 The Ligand:GPCR:G12/13 complex dissociates BibTex
2010-05-22 R-HSA-751029 Liganded G12/13-activating GPCR acts as a GEF for G12/13 BibTex
2010-05-22 R-HSA-751027 Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 BibTex
2010-05-08 R-HSA-159179 UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG BibTex
2010-05-08 R-HSA-9632039 UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG BibTex
2010-05-08 R-HSA-9632038 UGT1A1 tetramer transfers GlcA from UDP-GlcA to BMG to form BDG BibTex
2010-05-08 R-HSA-159194 UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG BibTex
2010-04-23 R-HSA-499981 Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 BibTex
2010-02-06 R-HSA-8954327 UCKL1 phosphorylates urindine, cytidine BibTex
2009-12-12 R-HSA-201708 Frizzled receptors bind Wnts BibTex
2009-12-12 R-NUL-517516 Frizzled receptors bind Wnts BibTex
2009-12-12 R-HSA-445124 Patched binds Smoothened BibTex
2009-12-12 R-NUL-517521 Patched binds Smoothened BibTex
2009-12-12 R-HSA-443978 Receptor CCR11 binds CCL19, CCL21 & CCL25 BibTex
2009-12-12 R-HSA-444654 G-protein coupled bile acid receptor binds lithocholic acid BibTex
2009-12-12 R-HSA-444838 Relaxin receptor 1 binds relaxin 2 and 3 BibTex
2009-12-12 R-HSA-444879 Relaxin receptor 2 binds relaxin 2 and INSL3 BibTex
2009-12-12 R-HSA-445113 Urotensin-2 receptor binds urotensin-2 and 2B BibTex
2009-12-12 R-HSA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors BibTex
2009-12-12 R-HSA-444208 MLNR (GPR38) is a receptor for motilin BibTex
2009-12-12 R-HSA-444202 Receptor FFAR1 binds free fatty acids BibTex
2009-12-12 R-HSA-444572 Zinc is an agonist of GPR39 BibTex
2009-12-12 R-HSA-444191 GPR120 is a receptor for unsaturated long-chain free fatty acids BibTex
2009-12-12 R-MMU-444204 GPR120 is a receptor for unsaturated long-chain free fatty acids BibTex
2009-12-12 R-HSA-444691 Prokineticin receptors bind prokineticin BibTex
2009-12-12 R-HSA-444498 Thyrotropin-releasing hormone receptor binds thyrotropin BibTex
2009-12-12 R-HSA-444171 Receptor FFAR2 binds carboxylates BibTex
2009-12-12 R-HSA-444620 Neuropeptide S receptor binds neuropeptide S BibTex
2009-12-12 R-HSA-444047 Receptor FFAR3 binds carboxylates BibTex
2009-12-12 R-HSA-444661 HCAR2 binds HCAR2 ligands BibTex
2009-12-12 R-HSA-444523 CXCR5 binds CXCL13 BibTex
2009-12-12 R-HSA-444527 FPR is a receptor for formyl peptides BibTex
2009-12-12 R-HSA-444647 C3a receptor binds anaphylatoxin C3a BibTex
2009-12-12 R-HSA-444859 Relaxin 3 receptor 2 binds relaxin 3 and INSL5 BibTex
2009-12-12 R-HSA-444476 FPRL2 receptor binds a wide range of ligands BibTex
2009-12-12 R-HSA-444606 T1R2/T1R3 dimer is a sweet taste receptor BibTex
2009-12-12 R-HSA-444848 Relaxin 3 receptor 1 binds relaxin 3 BibTex
2009-12-12 R-HSA-444705 T1R1/T1R3 dimer is the umami taste receptor BibTex
2009-12-12 R-HSA-517536 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine BibTex
2009-06-02 R-HSA-400063 Low conductance potassium channels in pancreatic beta cells open in response to epinephrine BibTex
2009-06-02 R-HSA-400046 L-type Calcium Channels close in pancreatic beta cells BibTex
2009-06-02 R-HSA-400097 G-beta:G-gamma inhibits Adenylate cyclase BibTex
2009-06-02 R-HSA-400037 Gi,Go Heterotrimeric G-protein complex dissociates BibTex
2009-06-02 R-HSA-400092 Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins BibTex
2009-06-02 R-HSA-400071 Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline BibTex
2009-05-29 R-HSA-420739 GPRC6A can bind L-alpha amino acids and calcium BibTex
2009-05-29 R-HSA-8982640 G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) BibTex
2009-05-29 R-HSA-420883 Opsins act as GEFs for G alpha-t BibTex
2009-05-29 R-HSA-8982637 Opsins binds G alpha-t BibTex
2009-05-29 R-HSA-419841 Light stimulates opsin receptors BibTex
2009-05-29 R-HSA-391937 UDP/CysLT receptor can bind cysteinyl leukotrienes BibTex
2009-05-29 R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 BibTex
2009-05-29 R-HSA-391943 CYSLT2 binds LTC4,LTD4,LTE4 BibTex
2009-05-29 R-HSA-391941 BLT receptors can bind LTB4 BibTex
2009-05-29 R-HSA-391905 Oxoeicosanoid receptor can bind oxoeicosanoid BibTex
2009-05-29 R-HSA-391934 DP2 receptor can bind PGD2 BibTex
2009-05-29 R-HSA-391935 DP1 receptor can bind PGD2 BibTex
2009-05-29 R-HSA-391939 TP receptor can bind thromboxane BibTex
2009-05-29 R-HSA-417829 P2RY12 binds ADP BibTex
2009-05-29 R-HSA-417843 P2Y13 binds ADP BibTex
2009-05-29 R-HSA-417858 P2Y14 receptor can bind to UDP-glucose BibTex
2009-05-29 R-HSA-420688 GABAB heterodimeric receptor binds GABA BibTex
2009-05-29 R-HSA-418904 A1 and A3 receptors bind adenosine BibTex
2009-05-29 R-HSA-419426 Cannabinoid receptors can bind cannabinoids BibTex
2009-05-29 R-HSA-417898 P2Y4 receptor can bind to UTP BibTex
2009-05-29 R-HSA-417908 P2RY1 binds ADP BibTex
2009-05-29 R-HSA-391913 FPR2 binds FPR2 ligands BibTex
2009-05-29 R-HSA-420724 CASR binds Ca2+ BibTex
2009-05-29 R-HSA-417927 P2Y2 receptor binds ATP and UTP BibTex
2009-05-29 R-HSA-419861 Melanospin is stimulated by light BibTex
2009-05-29 R-HSA-373075 Metabotropic glutamate receptors bind glutamate BibTex
2009-05-29 R-HSA-417820 P2Y9 receptor can bind to LPA BibTex
2009-05-29 R-HSA-417890 P2Y5 receptor can bind to LPA BibTex
2009-05-29 R-HSA-163625 Glucagon binds to Glucagon receptor BibTex
2009-05-29 R-HSA-417896 P2Y6 receptor can bind to UDP BibTex
2009-05-29 R-HSA-417842 P2Y10 receptor can bind to LPA BibTex
2009-05-29 R-HSA-391942 IP receptor can bind prostacyclin BibTex
2009-05-29 R-HSA-419843 CALCA(83-119) binds CALCR BibTex
2009-05-29 R-HSA-420173 CRHR1,CRHR2-1 binds CRH,UCN BibTex
2009-05-29 R-HSA-420233 VIP receptors bind VIP BibTex
2009-05-29 R-HSA-420489 Parathyroid hormone receptor can bind parathyroid hormone BibTex
2009-05-29 R-HSA-420243 GHRH receptor binds GHRH BibTex
2009-05-29 R-HSA-420127 CGRP receptor can bind calcitonin gene-related peptides BibTex
2009-05-29 R-HSA-420123 Glucagon-like receptor 2 binds GLP2 BibTex
2009-05-29 R-HSA-420131 The PACAP receptor binds PACAP BibTex
2009-05-29 R-HSA-418925 ADORA2A,B bind Ade-Rib BibTex
2009-05-29 R-HSA-420202 Secretin receptor binds secretin BibTex
2009-05-29 R-HSA-420265 AMY1-3 bind IAPP(34-70) BibTex
2009-05-29 R-HSA-420214 The adrenomedullin receptor can bind adrenomedullin and intermedin BibTex
2009-05-29 R-HSA-420274 GIP receptor binds gastric inhibitory peptide BibTex
2009-05-29 R-HSA-419334 Melatonin receptors can bind melatonin BibTex
2009-05-29 R-HSA-418918 The UDP/CysLT (P2Y17) receptor can bind UTP BibTex
2009-05-29 R-HSA-417825 P2Y11 receptor can bind to ATP BibTex
2009-05-29 R-HSA-419351 PAF receptor binds platelet activating factor BibTex
2009-05-29 R-HSA-9690449 S1PR1 bind S1P BibTex
2009-05-29 R-HSA-419428 S1PR2-5 bind S1P BibTex
2009-05-29 R-HSA-419389 LPA-binding receptors bind LPA BibTex
2009-05-29 R-HSA-391940 EP2 and EP4 receptors can bind PGE2 BibTex
2009-05-29 R-HSA-391936 EP1 receptor can bind PGE2 BibTex
2009-05-29 R-HSA-416929 PTGFR binds PGF2a BibTex
2009-05-29 R-HSA-391933 EP3 receptor can bind PGE2 BibTex
2009-05-27 R-HSA-879762 Expression of DBP BibTex
2009-05-27 R-HSA-549364 Expression of SERPINE1 (PAI-1) BibTex
2009-05-27 R-HSA-549428 Expression of FACTOR VII (F7) BibTex
2009-05-27 R-HSA-879798 Expression of DEC1 (BHLHE40, BHLHB2) BibTex
2009-05-27 R-HSA-549424 Expression of CCRN4L (NOCTURNIN) BibTex
2009-05-27 R-HSA-879770 Expression of DEC2 (BHLHE41, BHLHB3) BibTex
2009-05-27 R-HSA-5663105 p-BMAL1:p-CLOCK,NPAS2 binds BHLHE41 (DEC2) gene BibTex
2009-05-27 R-HSA-5663138 p-BMAL1:p-CLOCK,NPAS2 binds CCRN4L (NOCTURNIN) gene BibTex
2009-05-27 R-HSA-5663170 p-BMAL1:p-CLOCK,NPAS2 binds BHLHE40 gene BibTex
2009-05-27 R-HSA-879782 Expression of AVP BibTex
2009-05-27 R-HSA-5663165 p-BMAL1:p-CLOCK,NPAS2 binds AVP gene BibTex
2009-05-27 R-HSA-5663132 p-BMAL1:p-CLOCK,NPAS2 binds DBP gene BibTex
2009-05-27 R-HSA-5663122 p-BMAL1:p-CLOCK,NPAS2 binds NAMPT gene BibTex
2009-05-27 R-HSA-5663124 p-BMAL1:p-CLOCK,NPAS2 binds SERPINE1 gene BibTex
2009-05-27 R-HSA-5663127 p-BMAL1:p-CLOCK,NPAS2 binds F7 gene BibTex
2009-05-27 R-HSA-549355 CRY proteins stabilize unphosphorylated BMAL1:CLOCK,NPAS2 BibTex
2009-05-27 R-HSA-400282 CRY proteins are ubiquitinylated BibTex
2009-05-27 R-HSA-400272 FBXL3 binds phosphorylated CRY proteins BibTex
2009-05-27 R-HSA-400267 BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins BibTex
2009-05-27 R-HSA-400219 Beta-TrCP1 binds phosphorylated PER proteins BibTex
2009-05-27 R-HSA-400256 CRY:PER heterodimer binds the BMAL1:CLOCK/NPAS2 heterodimer BibTex
2009-05-27 R-HSA-549385 CRY:PER:Kinase complex translocates to the nucleus BibTex
2009-05-27 R-HSA-400382 CSNK1E,CSNK1D phosphorylate CRY and PER proteins BibTex
2009-05-27 R-HSA-549493 Expression of PERIOD-2 BibTex
2009-05-27 R-HSA-5663118 p-BMAL1:p-CLOCK,NPAS2 binds PER2 gene BibTex
2009-05-27 R-HSA-549470 Expression of CRYPTOCHROME-2 BibTex
2009-05-27 R-HSA-549533 Expression of PERIOD-1 BibTex
2009-05-27 R-HSA-5663174 p-BMAL1:p-CLOCK,NPAS2 binds PER1 gene BibTex
2009-05-27 R-HSA-549467 Expression of CRYPTOCHROME-1 BibTex
2009-05-27 R-HSA-5663120 p-BMAL1:p-CLOCK,NPAS2 binds CRY1 gene BibTex
2009-05-27 R-HSA-549475 Expression of NR1D1 (REV-ERBA) BibTex
2009-05-27 R-HSA-5663155 p-BMAL1:p-CLOCK,NPAS2 binds NR1D1 gene BibTex
2009-05-27 R-HSA-879724 Expression of PPARA BibTex
2009-05-27 R-HSA-5663156 p-BMAL1:p-CLOCK,NPAS2 binds PPARA gene BibTex
2009-05-27 R-HSA-421320 BMAL1:CLOCK,NPAS2 heterodimer is phosphorylated and translocates to the nucleus BibTex
2009-05-27 R-HSA-400228 BMAL1 binds CLOCK,NPAS2 forming BMAL1:CLOCK,NPAS2 heterodimer BibTex
2009-05-27 R-HSA-400342 Expression of ARNTL (BMAL1) BibTex
2009-05-27 R-HSA-5669302 p-BMAL1:p-CLOCK,NPAS2 binds RORA gene BibTex
2009-05-27 R-MMU-5669295 p-Bmal1:p-Clock,Npas2 binds Rora gene BibTex
2009-05-27 R-HSA-560498 Expression of Lipoprotein lipase (LPL) BibTex
2009-05-27 R-HSA-560510 Expression of FABP4 (aP2) BibTex
2009-05-27 R-HSA-560473 Expression of ANGPTL4 BibTex
2009-05-27 R-HSA-560472 Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) BibTex
2009-05-27 R-HSA-560517 Expression of CD36 (platelet glycoprotein IV, FAT) BibTex
2009-05-27 R-HSA-1183032 Expression of GLUT4 BibTex
2009-05-27 R-HSA-1183003 Expression of Leptin BibTex
2009-05-27 R-HSA-560493 Expression of Perilipin (PLIN) BibTex
2009-05-27 R-HSA-1183058 Expression of Adiponectin BibTex
2009-05-27 R-HSA-560491 Expression of CEBPA BibTex
2009-05-27 R-HSA-381309 PPARG:RXRA heterodimer binds to fatty acid-like ligands BibTex
2009-05-27 R-HSA-381290 PPARG:RXRA heterodimer binds to PPARG corepressors BibTex
2009-05-27 R-HSA-381262 Formation of PPARG:RXRA heterodimer (ARF6 complex) BibTex
2009-05-27 R-HSA-381283 Expression of PPARG BibTex
2009-05-27 R-HSA-977271 Expression of EBF1 BibTex
2009-05-27 R-HSA-381377 Expression of KLF5 BibTex
2009-05-27 R-HSA-977392 Expression of CEBPD BibTex
2009-05-27 R-HSA-381337 Expression of CEBPB in adipogenesis BibTex
2009-03-02 R-HSA-9693347 HTR1A binds 5HT BibTex
2009-03-02 R-HSA-9692880 HRH3 binds Hist BibTex
2009-03-02 R-HSA-9656244 DRD2 binds DA BibTex
2009-03-02 R-HSA-390641 ADRA1A,B,D bind ADR,NAd BibTex
2009-03-02 R-HSA-390929 HTR1 and 5A receptors can bind serotonin BibTex
2009-03-02 R-HSA-390673 CHRM2,4 bind acetylcholine BibTex
2009-03-02 R-HSA-390846 D2D3,4 bind to DA BibTex
2009-03-02 R-HSA-390886 HRH4 binds Hist BibTex
2009-03-02 R-HSA-390912 HRH1 binds hist BibTex
2009-03-02 R-HSA-391372 GNRHR binds GNRH1,2 BibTex
2009-03-02 R-HSA-390930 5-HT2 receptor can bind serotonin BibTex
2009-03-02 R-HSA-388468 AVP(20-28) binds AVPR1A,B BibTex
2009-03-02 R-HSA-390649 CHRM1,3,5 bind acetylcholine BibTex
2009-03-02 R-HSA-390663 ADRA2A,B,C bind ADR,NAd BibTex
2009-03-02 R-HSA-391375 Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin BibTex
2009-03-02 R-HSA-391377 Luteinizing hormone receptor can bind LH BibTex
2009-03-02 R-HSA-390931 5-HT4, 6 and 7 receptors can bind serotonin BibTex
2009-03-02 R-HSA-390674 ADRB1 bind ADR,NAd BibTex
2009-03-02 R-HSA-391378 Follicle-stimulating hormone receptor can bind FSH BibTex
2009-03-02 R-HSA-391211 Trace amine-associated receptors can bind trace amines BibTex
2009-03-02 R-HSA-390835 DRD1,5 bind DA BibTex
2009-03-02 R-HSA-390909 HRH2 binds hist BibTex
2009-03-02 R-HSA-379044 Liganded Gs-activating GPCR acts as a GEF for Gs BibTex
2009-03-02 R-HSA-389424 The orphan QRFP receptor can bind neuropeptide QRFP BibTex
2009-03-02 R-HSA-389491 Two NPFF receptors can bind neuropeptide FF BibTex
2009-03-02 R-HSA-389487 Orexin 2 receptor can bind orexin-B neuropeptide BibTex
2009-03-02 R-HSA-389481 Orexin 1 receptor can bind orexin-A neuropeptide BibTex
2009-03-02 R-HSA-388900 Neurotensin receptors can bind neurotensins BibTex
2009-03-02 R-HSA-389026 Galanin receptors can bind galanin BibTex
2009-03-02 R-HSA-388529 Cholecystokinin receptors bind cholecystokinin BibTex
2009-03-02 R-HSA-383363 Tachykinin receptor 2 (NK2) binds to nuerokinin A BibTex
2009-03-02 R-HSA-383373 Tachykinin receptor 3 (NK3) binds to neurokinin B BibTex
2009-03-02 R-HSA-380076 Tachykinin receptor 1 (NK1) binds to substance P BibTex
2009-03-02 R-HSA-9731924 EDNRA binds EDNs BibTex
2009-03-02 R-HSA-389463 Proteinase-activated receptors can bind thrombin BibTex
2009-03-02 R-HSA-388560 EDNRA,EDNRB bind EDNs BibTex
2009-03-02 R-HSA-388981 The Kiss receptor GPR54 binds kisspeptin BibTex
2009-03-02 R-HSA-388596 Melanocortin receptors bind melanocortins BibTex
2009-03-02 R-HSA-388855 Prolactin-releasing hormone receptor binds PRH BibTex
2009-03-02 R-HSA-388605 POMC(138-176) binds MC2R BibTex
2009-03-02 R-HSA-388503 Oxytocin receptor bind oxytocin BibTex
2009-03-02 R-HSA-388863 Neuropeptide Y receptors can bind neuropeptide Y-related peptides BibTex
2009-03-02 R-HSA-9724290 GNRHR2 binds GNRH1,2 BibTex
2009-03-02 R-HSA-9611851 ADRB2 bind ADR,NAd BibTex
2009-03-02 R-HSA-9611852 ADRB3 bind ADR,NAd BibTex
2008-12-02 R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) BibTex
2008-12-02 R-NUL-9023186 Carboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87)) BibTex
2008-12-02 R-HSA-9023173 Insulin secretory granule docks at the plasma membrane BibTex
2008-12-02 R-HSA-9023171 Insulin secretory granule translocates across the cortical actin network BibTex
2008-12-02 R-HSA-265160 Insulin secretory granule translocates to cell cortex BibTex
2008-12-02 R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) BibTex
2008-12-02 R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) BibTex
2008-12-02 R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) BibTex
2008-12-02 R-NUL-9023166 Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54) BibTex
2008-12-02 R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) BibTex
2008-12-02 R-MMU-216806 Processing of Proinsulin to Insulin BibTex
2008-12-02 R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) BibTex
2008-12-02 R-HSA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule BibTex
2008-12-02 R-HSA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium BibTex
2008-12-02 R-HSA-265010 Proinsulin translocates from the endoplasmic reticulum to the Golgi BibTex
2008-12-02 R-HSA-264997 P4HB mediates disulfide bond formation in Proinsulin BibTex
2008-12-02 R-HSA-1791121 Expression of XBP1(S) BibTex
2008-12-02 R-HSA-1791150 Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5) BibTex
2008-12-02 R-HSA-1791082 Expression of Calreticulin BibTex
2008-12-02 R-HSA-1791163 Expression of HSP90B1 (Endoplasmin) BibTex
2008-12-02 R-HSA-1791076 Expression of ADD1 (Adducin alpha) BibTex
2008-12-02 R-HSA-1791143 Expression of YIF1A BibTex
2008-12-02 R-HSA-1791137 Expression of Talin-1 BibTex
2008-12-02 R-HSA-1791138 Expression of TPP1 BibTex
2008-12-02 R-HSA-1791139 Expression of SRPR (SRP Receptor subunit alpha) BibTex
2008-12-02 R-HSA-1791075 Expression of DNAJB11 BibTex
2008-12-02 R-HSA-1791084 Expression of SYVN1 (HRD1) BibTex
2008-12-02 R-HSA-1791144 Expression of EXTL3 BibTex
2008-12-02 R-HSA-1791083 Expression of Sec12 BibTex
2008-12-02 R-HSA-1791156 Expression of TATDN2 BibTex
2008-12-02 R-HSA-1791092 Expression of DCTN1 BibTex
2008-12-02 R-HSA-1791157 Expression of DNAJC3 (p58IPK) BibTex
2008-12-02 R-HSA-1791158 Expression of CXXC1 BibTex
2008-12-02 R-HSA-1791088 Expression of GFPT1 BibTex
2008-12-02 R-HSA-1791154 Expression of GOSR2 BibTex
2008-12-02 R-HSA-1791155 Expression of EDEM BibTex
2008-12-02 R-HSA-1791164 Expression of SSR1 (Trap alpha) BibTex
2008-12-02 R-HSA-1791102 Expression of C19orf10 BibTex
2008-12-02 R-HSA-1791167 Expression of SERP1 (RAMP4) BibTex
2008-12-02 R-HSA-1791096 Expression of PPP2R5B BibTex
2008-12-02 R-HSA-1791172 Expression of WIPI1 BibTex
2008-12-02 R-HSA-1791108 Expression of SULT1A3 BibTex
2008-12-02 R-HSA-1791169 Expression of WFS1 BibTex
2008-12-02 R-HSA-1791116 Expression of DDX11 BibTex
2008-12-02 R-HSA-1791054 Expression of GSK3A BibTex
2008-12-02 R-HSA-1791112 Expression of HDGF BibTex
2008-12-02 R-HSA-1791177 Expression of KLHDC3 BibTex
2008-12-02 R-HSA-1791114 Expression of FKBP14 BibTex
2008-12-02 R-HSA-1791060 Expression of SRPRB (SRP Receptor subunit beta) BibTex
2008-12-02 R-HSA-1791124 Expression of DNAJB9 BibTex
2008-12-02 R-HSA-1791184 Expression of ATP6VOD1 BibTex
2008-12-02 R-HSA-1791057 Expression of TSPYL2 BibTex
2008-12-02 R-HSA-1791186 Expression of ZBTB17 BibTex
2008-12-02 R-HSA-1791122 Expression of PDIA5 BibTex
2008-12-02 R-HSA-1791058 Expression of Cullin-7 BibTex
2008-12-02 R-HSA-1791123 Expression of KDELR3 BibTex
2008-12-02 R-HSA-1791133 Expression of Sec31A BibTex
2008-12-02 R-HSA-1791069 Expression of ACADVL BibTex
2008-12-02 R-HSA-1791134 Expression of SHC1 BibTex
2008-12-02 R-HSA-1791071 Expression of PLA2G4B BibTex
2008-12-02 R-HSA-1791128 Expression of LMNA BibTex
2008-12-02 R-HSA-1791064 Expression of ARFGAP1 (GAP) BibTex
2008-12-02 R-HSA-1791066 Expression of HYOU1 BibTex
2008-12-02 R-HSA-1791130 Expression of CTDSP2 BibTex
2008-12-02 R-HSA-381412 IGFBP2 binds IGF forming IGF:IGFBP2 BibTex
2008-12-02 R-HSA-381543 IGFBP4 binds IGF forming IGF:IGFBP4 BibTex
2008-12-02 R-HSA-381496 Formation of the IGF:IGFBP3:ALS complex BibTex
2008-12-02 R-HSA-381446 Thrombin proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381545 Formation of the IGF:IGFBP5:ALS complex BibTex
2008-12-02 R-HSA-381537 PAPP-A2 proteolyzes IGF:IGFBP5:ALS BibTex
2008-12-02 R-HSA-381487 IGFBP1 binds IGF forming IGF:IGFBP1 BibTex
2008-12-02 R-HSA-381518 PAAP-A proteolyzes IGF:IGFBP4 BibTex
2008-12-02 R-HSA-381461 Plasmin proteolyzes IGF:IGFBP-3:ALS BibTex
2008-12-02 R-HSA-381500 Cathepsin G proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381503 IGFBP6 binds IGF forming IGF:IGFBP6 BibTex
2008-12-02 R-HSA-381435 Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381466 Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-1799335 Synthesis of nascent polypeptide containing signal sequence BibTex
2008-12-02 R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) BibTex
2008-12-02 R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex BibTex
2008-12-02 R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum BibTex
2008-12-02 R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein BibTex
2008-12-02 R-HSA-381086 Dissociation of PERK:BiP Heterodimer BibTex
2008-12-02 R-HSA-381087 Dimerization of PERK BibTex
2008-12-02 R-HSA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK BibTex
2008-12-02 R-HSA-381128 Translation of ATF4 BibTex
2008-12-02 R-HSA-1791118 Expression of ASNS (Asparagine Synthetase) BibTex
2008-12-02 R-HSA-1791173 Expression of ATF3 BibTex
2008-12-02 R-HSA-381158 ATF6:HSPA5 (ATF6-alpha:BiP) dissociates and HSPA5 binds unfolded protein BibTex
2008-12-02 R-HSA-381186 ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi BibTex
2008-12-02 R-HSA-381135 MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) BibTex
2008-12-02 R-HSA-420818 MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) BibTex
2008-12-02 R-HSA-381026 ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus BibTex
2008-12-02 R-HSA-517731 Expression of IL-8 BibTex
2008-12-02 R-HSA-1791180 Expression of IGFBP1 BibTex
2008-12-02 R-HSA-1791107 Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein BibTex
2008-12-02 R-HSA-1791056 Expression of CCL2 BibTex
2008-12-02 R-HSA-1791095 Expression of HERPUD BibTex
2008-12-02 R-HSA-381217 IRE1:BiP dissociates in response to unfolded protein BibTex
2008-12-02 R-HSA-381109 IRE1 binds IRE1 forming dimer BibTex
2008-12-02 R-HSA-381091 IRE1 dimer autophosphorylates BibTex
2008-12-02 R-HSA-381116 Phosphorylated IRE1 dimer binds ADP BibTex
2008-12-02 R-HSA-425923 IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced BibTex
2008-12-02 R-HSA-381203 XBP(S) mRNA is translated and XBP1(S) translocates to the nucleus BibTex
2008-12-02 R-HSA-1791131 Expression of PDIA6 (Protein disulfide-isomerase A6) BibTex
2008-11-29 R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 BibTex
2008-11-29 R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi BibTex
2008-11-29 R-HSA-378952 Thyrotropin is a heterodimer BibTex
2008-11-29 R-HSA-378975 Follitropin is a heterodimer BibTex
2008-11-29 R-HSA-265301 Corticotropin cleavage from POMC BibTex
2008-11-29 R-HSA-378978 CGA and CGB3 bind to form Human chorionic gonadotropin (hCG) BibTex
2008-11-29 R-HSA-378956 Luteinizing hormone is a heterodimer BibTex
2008-09-10 R-GGA-187608 ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) BibTex
2008-09-10 R-GGA-187617 argininosuccinate <=> fumarate + arginine BibTex
2008-09-10 R-GGA-187632 arginine + H2O => ornithine + urea BibTex
2008-09-10 R-GGA-187586 ATP + aspartate + citrulline <=> argininosuccinate + AMP + pyrophosphate BibTex
2008-09-10 R-GGA-187588 carbamoyl phosphate + ornithine => citrulline + orthophosphate BibTex
2008-06-12 R-HSA-350600 Antizyme inhibitor binds to OAZ and stablizes ODC complex BibTex
2008-06-12 R-HSA-350578 NQO1 interaction with ODC BibTex
2008-06-12 R-HSA-350567 Antizyme OAZ binds to Ornithine decarboxylase BibTex
2008-06-12 R-HSA-353125 26S proteosome degrades ODC holoenzyme complex BibTex
2008-06-12 R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine BibTex
2008-06-12 R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine BibTex
2008-06-12 R-HSA-141341 SMOX-3 oxidises SPN to SPM BibTex
2008-06-12 R-HSA-141348 PAO:FAD oxidises NASPM to PTCN BibTex
2008-06-12 R-HSA-141351 PAOX:FAD oxidises NASPN to SPM BibTex
2008-06-12 R-HSA-351229 N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) BibTex
2008-06-12 R-HSA-351201 N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal) BibTex
2008-06-12 R-HSA-351208 Spermidine => N-acetylated spermidine BibTex
2008-06-12 R-HSA-351207 Spermine => N-acetylated spermine BibTex
2008-06-12 R-HSA-70692 ornithine => putrescine + CO2 BibTex
2008-06-12 R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 BibTex
2008-06-12 R-HSA-350604 Agmatine + H2O <=> putrescine + urea BibTex
2008-06-12 R-HSA-350598 Arginine<=>Agmatine+CO2 BibTex
2008-06-12 R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met BibTex
2008-06-12 R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met BibTex
2008-05-28 R-HSA-211950 CYP24A1 24-hydroxylates CTL BibTex
2008-05-28 R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA BibTex
2008-05-28 R-HSA-211923 CYP26C1 4-hydroxylates 9cRA BibTex
2008-05-28 R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine BibTex
2008-05-28 R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde BibTex
2008-05-28 R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide BibTex
2008-05-28 R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide BibTex
2008-05-28 R-HSA-76434 Dehalogenation of carbon tetrachloride to form a free radical BibTex
2008-05-28 R-HSA-76416 Benzene is hydroxylated to phenol BibTex
2008-05-28 R-HSA-211929 CYP2C19 5-hydroxylates omeprazole BibTex
2008-05-28 R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation BibTex
2008-05-28 R-HSA-76426 N-atom dealkylation of caffeine BibTex
2008-05-28 R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO BibTex
2008-05-28 R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 BibTex
2008-05-28 R-HSA-211948 CYP3A4 can N-demethylate loperamide BibTex
2008-05-28 R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 BibTex
2008-05-28 R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone BibTex
2008-05-28 R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation BibTex
2008-05-28 R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole BibTex
2008-05-28 R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation BibTex
2008-05-28 R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 BibTex
2008-05-28 R-HSA-211983 CYP2J2 oxidises ARA BibTex
2008-05-28 R-HSA-211924 CYP4B1 12-hydroxylates ARA BibTex
2008-05-28 R-HSA-211904 CYP4F12 18-hydroxylates ARA BibTex
2008-05-28 R-HSA-76466 CYP4A11 12-hydroxylates DDCX BibTex
2008-05-28 R-HSA-192123 CYP27A1 27-hydroxylates CHOL BibTex
2008-05-28 R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE BibTex
2008-05-28 R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL BibTex
2008-05-28 R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE BibTex
2008-05-28 R-HSA-192051 CYP7A1 7-hydroxylates CHOL BibTex
2008-05-28 R-HSA-192061 CYP46A1 24-hydroxylates CHOL BibTex
2008-05-28 R-HSA-211951 CYP1B1 4-hydroxylates EST17b BibTex
2008-05-28 R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL BibTex
2008-05-28 R-HSA-211919 CYP4F8 19-hydroxylates PGH2 BibTex
2008-05-28 R-HSA-215526 CYP4F3 20-hydroxylates LTB4 BibTex
2008-05-28 R-HSA-211960 CYP2U1 19-hydroxylates ARA BibTex
2008-05-28 R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM BibTex
2008-05-28 R-HSA-211959 CYP3A43 6b-hydroxylates TEST BibTex
2008-05-28 R-HSA-211968 CYP2W1 oxidises INDOL BibTex
2008-05-28 R-HSA-211874 CYP2S1 4-hydroxylates atRA BibTex
2008-05-28 R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] BibTex
2008-05-28 R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ BibTex
2008-05-28 R-HSA-217255 FMO1:FAD N-oxidises TAM BibTex
2008-05-28 R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO BibTex
2008-05-28 R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA BibTex
2008-05-28 R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT BibTex
2008-05-28 R-HSA-141202 MAOB:FAD oxidatively deaminates TYR BibTex
2008-05-28 R-HSA-193997 CYP11B1 oxidises 11DCORT BibTex
2008-05-28 R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL BibTex
2008-05-28 R-HSA-174916 Formation of N-glucuronides BibTex
2008-05-28 R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates BibTex
2008-05-28 R-HSA-76373 N-hydroxylation of 4-aminobiphenyl BibTex
2008-05-28 R-HSA-176059 GST trimers transfer GS from GSH to luminal substrates BibTex
2008-05-28 R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) BibTex
2008-05-28 R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 BibTex
2008-05-28 R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates BibTex
2008-05-28 R-HSA-174394 GSS:Mg2+ dimer synthesizes GSH BibTex
2008-05-28 R-HSA-174367 GCL ligates L-Glu to L-Cys BibTex
2008-05-28 R-HSA-176669 N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP BibTex
2008-05-28 R-HSA-176604 taurolithocholate + PAPS => taurolithocholate sulfate + PAP BibTex
2008-05-28 R-HSA-159358 SULT1A3,4 dimers sulfate DA to DAOS BibTex
2008-05-28 R-HSA-176664 estrone + PAPS => estrone 3-sulfate + PAP BibTex
2008-05-28 R-HSA-176474 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP BibTex
2008-05-28 R-HSA-176631 dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP BibTex
2008-05-28 R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP BibTex
2008-05-28 R-HSA-158860 SULT1A1 dimer sulfonates NHABP BibTex
2008-05-28 R-HSA-176494 SULTs transfer (SO4)2- group to 27HCHOL BibTex
2008-05-28 R-HSA-176521 beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP BibTex
2008-05-28 R-HSA-176585 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP BibTex
2008-05-28 R-HSA-176517 SULTs transfer (SO4)2- group to PREG BibTex
2008-05-28 R-HSA-158468 SULT1A1 dimer sulfonates PARA to PARA-SO4 BibTex
2008-05-28 R-HSA-176646 p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP BibTex
2008-05-28 R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP BibTex
2008-05-28 R-HSA-158849 Phenol can form a sulfate conjugate BibTex
2008-05-28 R-HSA-159566 benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A BibTex
2008-05-28 R-HSA-159443 benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate BibTex
2008-05-28 R-HSA-159574 GLYAT-like proteins transfer glycine to ST-CoA to form SUA BibTex
2008-05-28 R-HSA-159567 ACSM2B-like proteins transform ST to ST-CoA BibTex
2008-05-28 R-HSA-177160 phenylacetyl-CoA + glutamine => phenylacetyl glutamine + Coenzyme A BibTex
2008-05-28 R-HSA-177157 phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate BibTex
2008-05-28 R-HSA-158832 The acetyl group from acetyl-CoA is transferred to the NAT2 BibTex
2008-05-28 R-HSA-174967 NAT2 acetylation BibTex
2008-05-28 R-HSA-174963 NAT1 acetylation BibTex
2008-05-28 R-HSA-174959 The acetyl group from acetyl-CoA is transferred to the NAT1 BibTex
2008-05-28 R-HSA-174368 SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen BibTex
2008-05-28 R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate BibTex
2008-05-28 R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] BibTex
2008-05-28 R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ BibTex
2008-05-28 R-HSA-70286 UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose BibTex
2008-05-28 R-HSA-209828 Tryptophan is hydroxylated BibTex
2008-05-28 R-HSA-209859 Decarboxylation of 5-hydroxytryptophan forms serotonin BibTex
2008-05-28 R-HSA-209823 Tyrosine is hydroxylated to dopa BibTex
2008-05-28 R-HSA-209924 Dopa is decarboxylated to dopamine BibTex
2008-05-28 R-HSA-175987 NNMT transfers CH3 from AdoMet to PY BibTex
2008-05-28 R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP BibTex
2008-05-28 R-HSA-175976 TMT transfers CH3 from AdoMet to BME BibTex
2008-05-28 R-HSA-175983 COMT transfer CH3 from AdoMet to 3,4DHBNZ BibTex
2008-05-28 R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy BibTex
2008-05-28 R-HSA-194678 CYP51A1 demethylates LNSOL BibTex
2008-05-28 R-RNO-209770 Photolytic cleavage and thermal isomerization of 7-dehydrocholesterol BibTex
2008-05-28 R-HSA-209754 Photolytic cleavage and thermal isomerization of 7-dehydroCHOL BibTex
2008-05-28 R-HSA-8963872 VD3 translocates from ER membrane to extracellular region BibTex
2008-05-28 R-HSA-209738 VD3 binds GC BibTex
2008-05-28 R-HSA-350147 VD3 translocates from extracellular region to ER membrane BibTex
2008-05-28 R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D BibTex
2008-05-28 R-HSA-209944 25(OH)D binds GC BibTex
2008-05-28 R-HSA-350186 CUBN binds GC:25(OH)D BibTex
2008-05-28 R-HSA-350168 LRP2-mediated uptake of extracellular CUBN:GC:25(OH)D BibTex
2008-05-28 R-HSA-209760 Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen BibTex
2008-05-28 R-HSA-350158 LGMN degrades GC BibTex
2008-05-28 R-HSA-209766 25(OH)D translocates from lysosomal lumen to cytosol BibTex
2008-05-28 R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D BibTex
2008-05-28 R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it BibTex
2008-05-28 R-HSA-174374 MTR transfers CH3 from MeCbl to HCYS BibTex
2008-05-28 R-HSA-351596 Dopamine translocates to a secretory vesicle BibTex
2008-05-28 R-HSA-209891 Dopamine is oxidised to noradrenaline BibTex
2008-05-28 R-HSA-351604 Noradrenaline translocates to the cytosol BibTex
2008-05-28 R-HSA-209903 Noradrenaline is converted to adrenaline BibTex
2008-05-28 R-HSA-350901 Iodide is organified BibTex
2008-05-28 R-HSA-209815 Tyrosine is monoiodinated BibTex
2008-05-28 R-HSA-209921 Monoiodinated tyrosine can be deiodinated BibTex
2008-05-28 R-HSA-209960 Diiodinated tyrosine can be deiodinated BibTex
2008-05-28 R-HSA-209973 Tyrosine is diiodinated BibTex
2008-05-28 R-HSA-209840 Two DITs combine to form thyroxine BibTex
2008-05-28 R-HSA-209910 Iodide is taken up by thyroid epithelial cells BibTex
2008-05-28 R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) BibTex
2008-05-28 R-HSA-209772 Thyroxine is deiodinated to triiodothyronine BibTex
2008-05-28 R-HSA-209925 DIT and MIT combine to form triiodothyronine BibTex
2008-05-28 R-HSA-209792 N-acetylation of serotonin BibTex
2008-05-28 R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin BibTex
2008-01-12 R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 BibTex
2008-01-12 R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH BibTex
2007-07-31 R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA BibTex
2007-07-31 R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis BibTex
2007-07-31 R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine BibTex
2007-07-31 R-HSA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane BibTex
2007-07-31 R-HSA-200406 CPT1A,B transfers PALM to CAR BibTex
2007-04-30 R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol BibTex
2007-04-30 R-HSA-193801 Influx of 27-hydroxycholesterol BibTex
2007-04-30 R-HSA-193812 Efflux of 27-hydroxycholesterol BibTex
2007-04-30 R-HSA-193399 Cholate is translocated from the peroxisomal matrix to the cytosol BibTex
2007-04-30 R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH BibTex
2007-04-30 R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region BibTex
2007-04-30 R-HSA-192315 Bile salts are translocated from the peroxisomal matrix to the cytosol BibTex
2007-04-30 R-HSA-192312 Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate BibTex
2007-04-30 R-HSA-192341 Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA BibTex
2007-04-30 R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA BibTex
2007-04-30 R-HSA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA BibTex
2007-04-30 R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) BibTex
2007-04-30 R-HSA-192056 Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA BibTex
2007-04-30 R-HSA-192325 25(R) THCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-04-30 R-HSA-193401 THCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-04-30 R-HSA-192137 THCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-04-30 R-HSA-191971 THCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-04-30 R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) BibTex
2007-04-30 R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al BibTex
2007-04-30 R-HSA-193832 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol BibTex
2007-04-30 R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one BibTex
2007-04-30 R-HSA-193763 Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA BibTex
2007-04-30 R-HSA-193761 25(R) TetraHCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-04-30 R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-04-30 R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-04-30 R-HSA-193722 TetraHCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-04-30 R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) BibTex
2007-04-30 R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al BibTex
2007-04-30 R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol BibTex
2007-04-30 R-HSA-193774 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol BibTex
2007-04-30 R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one BibTex
2007-04-30 R-HSA-193491 Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate BibTex
2007-04-30 R-HSA-193533 Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA BibTex
2007-04-30 R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA BibTex
2007-04-30 R-HSA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA BibTex
2007-04-30 R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA BibTex
2007-04-30 R-HSA-193452 Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA BibTex
2007-04-30 R-HSA-194187 SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol BibTex
2007-04-30 R-HSA-194153 ABCC3 transports bile salts from cytosol to extracellular region BibTex
2007-04-30 R-HSA-194130 Transport (influx) of bile salts and acids by OATP-A BibTex
2007-04-30 R-HSA-194083 SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol BibTex
2007-04-30 R-HSA-194079 SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol BibTex
2007-04-30 R-HSA-193776 Efflux of 24-hydroxycholesterol BibTex
2007-04-30 R-HSA-193767 Influx of 24-hydroxycholesterol BibTex
2007-04-30 R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL BibTex
2007-04-30 R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated BibTex
2007-04-30 R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one BibTex
2007-04-30 R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one BibTex
2007-04-30 R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one BibTex
2007-04-30 R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one BibTex
2007-04-30 R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol BibTex
2007-04-30 R-HSA-193715 5beta-cholestan-3alpha,7alpha,24(S)-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-193792 CYP27A1 27-hydroxylates 5?-CHOL3?,7?,24(s)-triol BibTex
2007-04-30 R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one BibTex
2007-04-30 R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol BibTex
2007-04-30 R-HSA-192010 5beta-cholestan-3alpha, 7alpha, 12alpha-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol BibTex
2007-04-30 R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-04-30 R-HSA-159431 Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine BibTex
2007-04-30 R-HSA-194121 SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol BibTex
2007-04-30 R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al BibTex
2007-04-30 R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) BibTex
2007-04-30 R-HSA-193786 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-04-30 R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-04-30 R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-04-30 R-HSA-193753 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-04-30 R-HSA-193736 Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA BibTex
2007-04-30 R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one BibTex
2007-04-30 R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol BibTex
2007-04-30 R-HSA-193808 5beta-cholestan-3alpha,7alpha,27-triol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one BibTex
2007-04-30 R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol BibTex
2007-04-30 R-HSA-193537 5beta-cholestan-3alpha, 7alpha-diol is translocated from the cytosol to the mitochondrial matrix BibTex
2007-04-30 R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol BibTex
2007-04-30 R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al BibTex
2007-04-30 R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) BibTex
2007-04-30 R-HSA-193519 DHCA is translocated from the mitochondrial matrix to the cytosol BibTex
2007-04-30 R-HSA-193424 DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) BibTex
2007-04-30 R-HSA-193407 DHCA is conjugated with Coenzyme A (SLC27A5 BACS) BibTex
2007-04-30 R-HSA-193482 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome BibTex
2007-04-21 R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO BibTex
2007-04-21 R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST BibTex
2007-04-21 R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST BibTex
2007-04-21 R-HSA-193996 11DCORST translocates from cytosol to mitochondrial matrix BibTex
2007-04-21 R-HSA-193964 CYP21A2 21-hydroxylates PROG BibTex
2007-04-21 R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 BibTex
2007-04-21 R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b BibTex
2007-04-21 R-HSA-194036 Cortisol translocates from the mitochondrial matrix to the cytosol BibTex
2007-04-21 R-HSA-193997 CYP11B1 oxidises 11DCORT BibTex
2007-04-21 R-HSA-194025 11-deoxycortisol translocates to the mitochondrion BibTex
2007-04-21 R-HSA-193981 CYP21A2 oxidises 17HPROG BibTex
2007-04-21 R-HSA-193961 Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone BibTex
2007-04-21 R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol BibTex
2007-04-21 R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR BibTex
2007-04-21 R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST BibTex
2007-04-21 R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST BibTex
2007-04-21 R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST BibTex
2007-04-21 R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST BibTex
2007-04-21 R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST BibTex
2007-04-21 R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG BibTex
2007-04-21 R-HSA-193052 Pregn-5-ene-3,20-dione isomerizes to progesterone BibTex
2007-04-21 R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione BibTex
2007-04-21 R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST BibTex
2007-04-21 R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA BibTex
2007-04-21 R-HSA-193068 CYP17A1 17-hydroxylates PREG BibTex
2007-04-21 R-HSA-193097 Pregnenolone translocates from the mitochondrial matrix to the cytosol BibTex
2007-04-21 R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL BibTex
2007-04-21 R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol BibTex
2007-04-21 R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol BibTex
2007-04-21 R-HSA-196086 Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane BibTex
2007-04-21 R-HSA-196126 CHOL translocates from cytosol to mitochondrial intermembrane space BibTex
2007-01-22 R-HSA-191366 Squalene 2,3-epoxide cyclizes, forming lanosterol BibTex
2007-01-22 R-HSA-191299 Squalene is oxidized to its epoxide BibTex
2007-01-22 R-HSA-191402 Reduction of presqualene diphosphate to form squalene BibTex
2007-01-22 R-HSA-191405 Two FPP molecules dimerize to form presqualene diphosphate BibTex
2007-01-22 R-HSA-191303 FDPS dimer transfers IPPP to GPP BibTex
2007-01-22 R-HSA-191322 FDPS dimer transfers IPPP to DMAPP BibTex
2007-01-22 R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP BibTex
2007-01-22 R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP BibTex
2007-01-22 R-HSA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate BibTex
2007-01-22 R-HSA-191414 MVD decarboxylates MVA5PP to IPPP BibTex
2007-01-22 R-HSA-191422 Mevalonate-5-phosphate is further phosphorylated. BibTex
2007-01-22 R-HSA-191380 Mevalonate is phosphorylated to mevalonate-5-phosphate BibTex
2007-01-22 R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA BibTex
2007-01-22 R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA BibTex
2006-08-29 R-HSA-183122 Factor D cleaves C3b-bound Factor B BibTex
2006-08-29 R-HSA-183126 Factor B binds to surface-associated C3b BibTex
2006-07-04 R-HSA-173740 Factor B binds to C3(H2O) BibTex
2006-07-04 R-HSA-173745 Factor D cleaves C3(H2O)-bound Factor B BibTex
2006-07-04 R-HSA-183130 C3(H2O):Factor Bb cleaves C3 to C3b and C3a BibTex
2006-07-04 R-HSA-173754 Properdin stabilizes C3b:Bb bound to cell surfaces BibTex
2006-07-04 R-HSA-174551 Formation of alternative pathway C5 convertase BibTex
2006-07-04 R-HSA-166721 MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa BibTex
2006-07-04 R-HSA-166726 Activation of MASPs BibTex
2006-07-04 R-HSA-166792 Conversion of C2 into C2a and C2b BibTex
2006-07-04 R-HSA-173626 Activation of C1r BibTex
2006-07-04 R-HSA-173631 Activation of C1s BibTex
2006-07-04 R-HSA-166753 Conversion of C4 into C4a and C4b BibTex
2006-07-04 R-HSA-166795 Formation of Classical C3 convertase (C4b:C2a complex) BibTex
2006-07-04 R-HSA-166817 Cleavage of C3 by C3 convertases BibTex
2006-07-04 R-HSA-173680 Activation of C5 BibTex
2006-07-04 R-HSA-2559464 TLR6/2 ligand associates with CD14 and CD36 within lipid rafts BibTex
2006-07-04 R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 BibTex
2006-07-04 R-HSA-168951 TLR1:TLR2 is recruited to ligand:CD14 BibTex
2006-07-04 R-HSA-173705 C5b binds C6 BibTex
2006-07-04 R-HSA-173709 C7 binds C5b:C6 BibTex
2006-07-04 R-HSA-173720 C5b:C6:C7 translocates to the plasma membrane BibTex
2006-07-04 R-HSA-173723 C8 binds C5b:C6:C7 BibTex
2006-07-04 R-HSA-173725 C9 binds C5b:C6:C7:C8 BibTex
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