Marc E Gillespie

 ORCID
https://orcid.org/0000-0002-5766-1702
Project
Reactome
Affiliation
St. John's University, Cold Spring Harbor Laboratory, NYU School of Medicine, Department of Biochemistry
Authored Pathways (78/78)
Date Identifier Pathway Reference
2024-03-06 R-HSA-168898 Toll-like Receptor Cascades BibTex
2024-03-06 R-HSA-73886 Chromosome Maintenance BibTex
2022-05-10 R-HSA-9772573 Late SARS-CoV-2 Infection Events BibTex
2022-05-10 R-HSA-9772572 Early SARS-CoV-2 Infection Events BibTex
2020-09-09 R-HSA-9694614 Attachment and Entry BibTex
2020-08-14 R-HSA-9694516 SARS-CoV-2 Infection BibTex
2020-05-26 R-HSA-9679506 SARS-CoV Infections BibTex
2020-03-24 R-HSA-9678108 SARS-CoV-1 Infection BibTex
2020-03-24 R-HSA-9678110 Attachment and Entry BibTex
2018-05-26 R-HSA-9609646 HCMV Infection BibTex
2018-05-26 R-HSA-9610379 HCMV Late Events BibTex
2018-05-26 R-HSA-9609690 HCMV Early Events BibTex
2015-01-13 R-HSA-162906 HIV Infection BibTex
2015-01-13 R-HSA-162587 HIV Life Cycle BibTex
2014-03-03 R-HSA-5423599 Diseases of Mismatch Repair (MMR) BibTex
2013-11-21 R-HSA-5205647 Mitophagy BibTex
2013-11-21 R-HSA-8934903 Receptor Mediated Mitophagy BibTex
2013-11-21 R-HSA-5205685 PINK1-PRKN Mediated Mitophagy BibTex
2013-11-18 R-HSA-168277 Influenza Virus Induced Apoptosis BibTex
2013-11-18 R-HSA-168276 NS1 Mediated Effects on Host Pathways BibTex
2013-11-18 R-HSA-169131 Inhibition of PKR BibTex
2013-11-18 R-HSA-168315 Inhibition of Host mRNA Processing and RNA Silencing BibTex
2013-11-18 R-HSA-168305 Inhibition of Interferon Synthesis BibTex
2013-11-18 R-HSA-168888 Inhibition of IFN-beta BibTex
2013-03-07 R-HSA-162588 Budding and maturation of HIV virion BibTex
2013-03-07 R-HSA-175474 Assembly Of The HIV Virion BibTex
2013-03-07 R-HSA-174495 Synthesis And Processing Of GAG, GAGPOL Polyproteins BibTex
2013-03-07 R-HSA-174490 Membrane binding and targetting of GAG proteins BibTex
2013-03-07 R-HSA-171286 Synthesis and processing of ENV and VPU BibTex
2013-02-13 R-HSA-1474165 Reproduction BibTex
2013-02-13 R-HSA-1187000 Fertilization BibTex
2013-02-13 R-HSA-1300645 Acrosome Reaction and Sperm:Oocyte Membrane Binding BibTex
2013-02-13 R-HSA-2534343 Interaction With Cumulus Cells And The Zona Pellucida BibTex
2013-02-13 R-HSA-1300642 Sperm Motility And Taxes BibTex
2011-11-10 R-HSA-5545483 Defective Mismatch Repair Associated With MLH1 BibTex
2011-11-10 R-HSA-5632987 Defective Mismatch Repair Associated With PMS2 BibTex
2011-11-10 R-HSA-5632968 Defective Mismatch Repair Associated With MSH6 BibTex
2011-11-10 R-HSA-5632927 Defective Mismatch Repair Associated With MSH3 BibTex
2011-11-10 R-HSA-5632928 Defective Mismatch Repair Associated With MSH2 BibTex
2010-08-10 R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) BibTex
2009-08-27 R-HSA-432720 Lysosome Vesicle Biogenesis BibTex
2009-08-27 R-HSA-432722 Golgi Associated Vesicle Biogenesis BibTex
2009-03-09 R-HSA-445355 Smooth Muscle Contraction BibTex
2009-02-10 R-HSA-397014 Muscle contraction BibTex
2009-02-10 R-HSA-390522 Striated Muscle Contraction BibTex
2008-05-22 R-HSA-199992 trans-Golgi Network Vesicle Budding BibTex
2007-07-25 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis BibTex
2007-07-25 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters BibTex
2007-07-25 R-HSA-164940 Nef mediated downregulation of MHC class I complex cell surface expression BibTex
2007-07-25 R-HSA-164939 Nef mediated downregulation of CD28 cell surface expression BibTex
2007-07-25 R-HSA-182218 Nef Mediated CD8 Down-regulation BibTex
2007-07-25 R-HSA-167590 Nef Mediated CD4 Down-regulation BibTex
2007-07-25 R-HSA-164944 Nef and signal transduction BibTex
2007-07-14 R-HSA-199977 ER to Golgi Anterograde Transport BibTex
2007-07-14 R-HSA-204005 COPII-mediated vesicle transport BibTex
2007-02-03 R-HSA-556833 Metabolism of lipids BibTex
2007-02-03 R-HSA-8978868 Fatty acid metabolism BibTex
2007-02-03 R-HSA-8979227 Triglyceride metabolism BibTex
2007-01-30 R-HSA-191859 snRNP Assembly BibTex
2006-03-30 R-HSA-168256 Immune System BibTex
2005-11-14 R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus BibTex
2005-11-10 R-HSA-112316 Neuronal System BibTex
2005-04-04 R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization BibTex
2005-03-13 R-HSA-159234 Transport of Mature mRNAs Derived from Intronless Transcripts BibTex
2004-08-31 R-HSA-75158 TRAIL signaling BibTex
2004-08-25 R-HSA-75893 TNF signaling BibTex
2004-08-19 R-HSA-75157 FasL/ CD95L signaling BibTex
2004-08-10 R-HSA-73887 Death Receptor Signaling BibTex
2003-10-25 R-HSA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids BibTex
2003-09-19 R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation BibTex
2003-09-19 R-HSA-77286 mitochondrial fatty acid beta-oxidation of saturated fatty acids BibTex
2003-09-19 R-HSA-77352 Beta oxidation of butanoyl-CoA to acetyl-CoA BibTex
2003-09-19 R-HSA-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA BibTex
2003-09-19 R-HSA-77348 Beta oxidation of octanoyl-CoA to hexanoyl-CoA BibTex
2003-09-19 R-HSA-77305 Beta oxidation of palmitoyl-CoA to myristoyl-CoA BibTex
2003-09-19 R-HSA-77285 Beta oxidation of myristoyl-CoA to lauroyl-CoA BibTex
2003-09-19 R-HSA-77310 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA BibTex
2003-09-19 R-HSA-77346 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA BibTex
Authored Reactions (180/180)
Date Identifier Reaction Reference
2020-09-09 R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors BibTex
2020-09-09 R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ BibTex
2020-09-09 R-HSA-9683478 CQ, HCQ diffuses from cytosol to endocytic vesicle lumen BibTex
2020-09-09 R-HSA-9685655 CTSL bind CTSL inhibitors BibTex
2020-09-09 R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis BibTex
2020-09-09 R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion BibTex
2020-09-09 R-HSA-9694287 Cleavage of S protein into S1:S2 BibTex
2020-09-09 R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid BibTex
2020-09-09 R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell BibTex
2020-09-09 R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis BibTex
2020-09-09 R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid BibTex
2020-09-09 R-HSA-9694723 Uncoating of SARS-CoV-2 Genome BibTex
2020-05-26 R-HSA-9686711 Endocytois of SARS-CoV-1 Virion BibTex
2020-05-05 R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis BibTex
2020-05-05 R-HSA-9686710 Cleavage of S protein into S1:S2 BibTex
2020-05-05 R-HSA-9686699 Fusion and Release of SARS-CoV-1 Nucleocapsid BibTex
2020-05-05 R-HSA-9686709 Uncoating of SARS-CoV-1 Genome BibTex
2020-04-22 R-HSA-9678128 Spike glycoprotein of SARS coronavirus binds ACE2 on host cell BibTex
2019-11-12 R-HSA-9698931 C Nucleocapsid Assembly BibTex
2019-03-09 R-HSA-9640368 Addition of Tegument to HCMV Nucleocapsid C BibTex
2019-02-12 R-HSA-9698924 B Nucleocapsid Assembly BibTex
2019-02-12 R-HSA-9698933 HCMV B Nucleocapsid Translocation BibTex
2019-02-12 R-HSA-9698930 HCMV C Nucleocapsid Translocation BibTex
2018-11-28 R-HSA-9698926 HCMV Genome Replication Completion BibTex
2018-11-28 R-HSA-9698929 pPR-AP:pAP cleaves the MCP:pPR-AP:pAP Complex BibTex
2018-11-28 R-HSA-9636128 Translocation of SCP, Triplex (TRI) complex, CVC complex, and Accessory Proteins from the cytoplasm into the nucleous BibTex
2018-11-28 R-HSA-9698932 Assembly of HCMV Procapsid BibTex
2018-11-28 R-HSA-9698925 Packaging of Viral Genome Into C Capsids BibTex
2018-10-03 R-HSA-9624033 Initiation of HCMV DNA Replication BibTex
2018-10-03 R-HSA-9698927 Assembly of the HCMV Genome DNA Replication Complex BibTex
2018-07-25 R-HSA-9614810 Activation of Latent HCMV Genome BibTex
2018-06-20 R-HSA-9614343 Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs BibTex
2018-06-14 R-HSA-9611147 Endocytic Uptake of HCMV Virion BibTex
2018-06-14 R-HSA-9611158 Fusion of HCMV Envelope with Plasma Membrane BibTex
2018-05-30 R-HSA-9610867 HCMV Binds Host Cell Receptor - Endocytic Pathway BibTex
2018-05-30 R-HSA-9609689 HCMV Binds to the Host Cell via heparan sulfate proteoglycans (HSPG) BibTex
2017-01-27 R-HSA-8959573 Phosphorylated FUNDC1 links damaged mitochondria to LC3 BibTex
2016-11-11 R-HSA-8948039 FUNDC1 is phosphorylated by CK2 BibTex
2016-11-02 R-HSA-8948146 FUNDC1 is phosphorylated by ULK1 at Ser17 BibTex
2016-11-02 R-HSA-8948143 p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 BibTex
2016-11-02 R-HSA-8948139 p-S13-FUNDC1 is dephosphorylated by PGAM5 BibTex
2016-11-02 R-HSA-8948136 ULK1 Translocates to the mitochondria BibTex
2014-05-30 R-HSA-5632970 MSH6 variant:MSH2-defective DNA mismatch repair BibTex
2014-05-30 R-HSA-5578663 MSH3 variant:MSH2-defective DNA mismatch repair BibTex
2014-05-24 R-HSA-5577259 MSH2 variant:MSH3-defective DNA mismatch repair BibTex
2014-05-24 R-HSA-5577244 MSH2 variant:MSH6-defective DNA mismatch repair BibTex
2014-05-21 R-HSA-5545484 MLH1 variants-defective DNA mismatch repair BibTex
2014-05-21 R-HSA-5632958 PMS2 variants-defective DNA mismatch repair BibTex
2014-05-09 R-HSA-5444511 Formation of MSH2:MSH3 Complex BibTex
2014-05-09 R-HSA-5444523 Formation of MSH1:PMS2 Complex BibTex
2014-05-09 R-HSA-5444516 Formation of MSH2:MSH6 Complex BibTex
2013-11-21 R-HSA-8959571 LC3 binds the autophagosome membrane Atg5-Atg12 complex BibTex
2013-11-21 R-HSA-5205681 Pink1 is cleaved on healthy mitochondria BibTex
2013-11-21 R-HSA-5205661 Pink1 is recruited from the cytoplasm to the mitochondria BibTex
2013-11-21 R-HSA-5205672 Uncleaved Pink1 accumulates in damaged mitochondria BibTex
2013-11-21 R-HSA-5205652 Pink1 recruits Parkin to the outer mitochondrial membrane. BibTex
2013-11-21 R-HSA-5205682 Parkin promotes the ubiquitination of mitochondrial substrates BibTex
2013-11-21 R-HSA-5205673 p62 binds ubiquitinated mitochondrial substrates BibTex
2013-11-21 R-HSA-5205649 p62 links damaged mitochondria to LC3 BibTex
2013-11-21 R-HSA-5205663 LC3 binds the autophagosome membrane Atg5-Atg12 complex BibTex
2013-11-18 R-HSA-168878 PB1-F2 binds to the mitochondrial adenine nucleotide translocator 3 ANT3, inducing apoptosis BibTex
2013-11-18 R-HSA-168865 NA activation of TGF-beta BibTex
2013-11-18 R-HSA-6791035 Release of NS1 homodimer BibTex
2013-11-18 R-HSA-168859 Binding of NS1 to cleavage and host polyadenylation specificity factor (CPSF) BibTex
2013-11-18 R-HSA-168883 Binding of NS1 to poly(A)-binding protein II (PABII) BibTex
2013-11-18 R-HSA-168891 Binding of NS1 to dsRNA BibTex
2013-11-18 R-HSA-1176059 Translocation of Influenza A virus nonstructural protein 1 (NS1A) into the nucleus BibTex
2013-11-18 R-HSA-168896 NS1 binds PKR BibTex
2013-03-07 R-HSA-3139027 Maturation of HIV Virion BibTex
2013-03-07 R-HSA-3159227 HIV Virion Budding BibTex
2013-03-07 R-HSA-3159232 Recruitment Of HIV Virion Budding Machinery BibTex
2013-03-07 R-HSA-3149454 Packaging of HIV virion on the host cell plasma membrane BibTex
2013-03-07 R-HSA-187213 Synthesis of GAG polyprotein BibTex
2013-03-07 R-HSA-184269 Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex BibTex
2013-03-07 R-HSA-3149434 Transport of GAG to the Plasma Membrane BibTex
2013-03-07 R-HSA-184392 N-myristoylation of GAG polyprotein by NMT2 BibTex
2013-03-07 R-HSA-184323 Monoubiquitination of N-myristoyl GAG polyprotein BibTex
2013-03-07 R-HSA-173647 Transport of trimeric gp41:gp120 to plasma membrane BibTex
2013-03-07 R-HSA-174491 Transport of trimeric ENV precursor to Golgi apparatus BibTex
2013-03-07 R-HSA-174494 Synthesis of ENV polyprotein BibTex
2013-03-07 R-HSA-174493 Glycosylation of ENV polyprotein BibTex
2013-03-07 R-HSA-3149432 Transport of VPU to Plasma Membrane BibTex
2013-03-07 R-HSA-187211 Splicing of HIV RNA transcript BibTex
2013-03-07 R-HSA-3149433 Synthesis of VPU protein BibTex
2013-03-07 R-HSA-3149440 Transport of VPU to Golgi apparatus BibTex
2013-02-13 R-HSA-1297275 CD9:Izumo Binding BibTex
2013-02-13 R-HSA-1297354 Acrosin Cleavage BibTex
2013-02-13 R-HSA-1297333 Association of Acrosin Heavy and Light Chain BibTex
2013-02-13 R-HSA-2534346 SPAM1 Binds Hyaluronic Acid BibTex
2013-02-13 R-HSA-1297338 Association of ADAM and B4GALT1 With ZP3 BibTex
2013-02-13 R-HSA-2534378 Hv1 Mediated H+ Permeability BibTex
2013-02-13 R-HSA-2534365 Slo3 Potassium Transport BibTex
2013-02-13 R-HSA-2534388 Progesterone Activation Of CatSper BibTex
2013-02-13 R-HSA-2534359 CatSper Channel Mediated Calcium Transport BibTex
2010-08-10 R-HSA-917730 Cargo Recognition And Sorting BibTex
2010-08-10 R-HSA-917696 Cargo Sequestration BibTex
2010-08-10 R-HSA-917700 MVB Vesicle Formation BibTex
2010-08-10 R-HSA-917693 ESCRT Disassembly BibTex
2009-11-18 R-HSA-445813 Phosphorylation of Smooth Muscle Myosin Light Chains BibTex
2009-08-27 R-HSA-376364 Vamp8 associated secretory vesicle to plasma membrane transport BibTex
2009-08-27 R-HSA-376369 Vamp2 associated secretory vesicle to plasma membrane transport BibTex
2009-08-27 R-HSA-421833 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture BibTex
2009-08-27 R-HSA-421831 trans-Golgi Network Coat Assembly BibTex
2009-08-27 R-HSA-421835 trans-Golgi Network Vesicle Scission BibTex
2009-08-27 R-HSA-421836 trans-Golgi Network Derived Vesicle Uncoating BibTex
2009-08-27 R-HSA-429815 Formation Of Bloc-1 Complex BibTex
2009-08-27 R-HSA-350769 trans-Golgi Network Coat Activation BibTex
2009-08-27 R-HSA-432712 Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane BibTex
2009-08-27 R-HSA-432706 trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly BibTex
2009-08-27 R-HSA-432707 trans-Golgi Network Lysosomal Vesicle Scission BibTex
2009-08-27 R-HSA-432688 trans-Golgi Network Derived Lysosomal Vesicle Uncoating BibTex
2009-08-27 R-HSA-376357 Vamp7 associated Lysosome to Plasma membrane transport BibTex
2009-08-13 R-HSA-434362 Recruitment Of Cytoplasmic Proteins To Vesicles BibTex
2009-02-23 R-HSA-375339 Pannexin 1/Pannexin2 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375342 Connexin 36 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375340 Connexin 62 mediated neuronal gap junction communication BibTex
2009-02-23 R-HSA-375330 Connexin 45/Connexin 36 mediated neuronal gap junction communication BibTex
2009-02-10 R-HSA-445797 MYLK (MLCK) Active Calmodulin Binding BibTex
2007-07-25 R-HSA-182286 Transport of MHC I:Nef:AP-1:PACS-1 Complex BibTex
2007-07-25 R-HSA-182263 Degradation of MHC I Complex BibTex
2007-07-25 R-HSA-182279 Formation of MHC I:Nef:AP-1:PACS-1 Complex BibTex
2007-07-25 R-HSA-182243 Formation of MHC I:Nef Complex BibTex
2007-07-25 R-HSA-167637 Internalization of Nef:CD28:Clathrin-Coated Pit Adapter Protein Complex BibTex
2007-07-25 R-HSA-167630 Formation of Nef CD28 cytoplasmic tail complex BibTex
2007-07-25 R-HSA-167633 Formation of Nef:Cd28:Clathrin-coated Pit Adapter Protein complex BibTex
2007-07-25 R-HSA-182171 Degradation of CD8 BibTex
2007-07-25 R-HSA-182186 Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-182198 Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-167597 Internalization of the CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-200879 Formation of a Nef:ARF1:CD4 complex BibTex
2007-07-25 R-HSA-167601 Degradation of CD4 BibTex
2007-07-25 R-HSA-167566 Nef mediated disruption of CD4:Lck Complex BibTex
2007-07-25 R-HSA-167537 Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-07-25 R-HSA-200908 Nef Binds and activates the Src-family tyrosine kinase Fyn BibTex
2007-07-25 R-HSA-164943 Nef mediated activation of the T-cell receptor BibTex
2007-07-25 R-HSA-200954 Nef Binds and activates the Src-family tyrosine kinase Lck BibTex
2007-07-25 R-HSA-200858 Nef Binds and activates the Src-family tyrosine kinase Hck BibTex
2007-07-14 R-HSA-204008 SEC31:SEC13 and v-SNARE recruitment BibTex
2007-07-14 R-HSA-203973 Vesicle budding BibTex
2007-07-14 R-HSA-5694527 Loss of SAR1B GTPase BibTex
2007-07-14 R-HSA-203977 SAR1 Activation And Membrane Binding BibTex
2007-07-14 R-HSA-203979 Coat Assembly BibTex
2007-01-30 R-HSA-191830 snRNP nuclear import and release BibTex
2007-01-30 R-HSA-191784 snRNA Cap hypermethylation BibTex
2007-01-30 R-HSA-191763 snRNP:Snurportin complex formation BibTex
2007-01-30 R-HSA-191790 Loading and methylation of Sm proteins onto SMN Complexes BibTex
2007-01-30 R-HSA-191825 Nuclear export of snRNA transcripts BibTex
2007-01-30 R-HSA-191786 snRNP complex assembly BibTex
2005-11-14 R-HSA-168297 Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein BibTex
2005-11-14 R-HSA-168317 Recruitment of Karyopherin Beta to form a Trimeric Complex BibTex
2005-11-14 R-HSA-168337 Docking and transport of the RNP:Karyopherin complex through the nuclear pore BibTex
2005-11-14 R-HSA-168310 Release of the RNP into the host cell nucleus BibTex
2005-03-13 R-HSA-159046 Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC BibTex
2005-01-27 R-HSA-159050 Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex BibTex
2005-01-27 R-HSA-158481 Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC BibTex
2005-01-27 R-HSA-158484 Release of the SLBP independent Histone mRNA from the NPC BibTex
2005-01-27 R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex BibTex
2005-01-27 R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex BibTex
2005-01-27 R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex BibTex
2005-01-27 R-HSA-77594 Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC BibTex
2005-01-27 R-HSA-158441 Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC BibTex
2005-01-27 R-HSA-158447 Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC BibTex
2004-08-25 R-HSA-83586 FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 BibTex
2004-08-25 R-HSA-75146 TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 BibTex
2004-08-25 R-HSA-83656 TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 BibTex
2004-03-13 R-HSA-77585 Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA BibTex
2004-01-19 R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation BibTex
2004-01-19 R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation BibTex
2004-01-19 R-HSA-109341 dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA BibTex
2004-01-19 R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA BibTex
2004-01-19 R-HSA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA BibTex
2003-09-02 R-HSA-73757 Binding of RRN3 to RNA Polymerase I BibTex
2003-07-01 R-HSA-390595 Calcium Binds Troponin-C BibTex
2003-07-01 R-HSA-390598 Myosin Binds ATP BibTex
2003-07-01 R-HSA-390593 ATP Hydrolysis By Myosin BibTex
2003-07-01 R-HSA-390597 Release Of ADP From Myosin BibTex
2003-07-01 R-HSA-445704 Calcium Binds Caldesmon BibTex
2003-07-01 R-HSA-445699 ATP Hydrolysis By Myosin BibTex
2003-07-01 R-HSA-445705 Release Of ADP From Myosin BibTex
2003-07-01 R-HSA-445700 Myosin Binds ATP BibTex
Reviewed Pathways (73/73)
Date Identifier Pathway Reference
2022-05-10 R-HSA-9727281 Translation of Accessory Proteins BibTex
2022-05-10 R-HSA-9733458 Induction of Cell-Cell Fusion BibTex
2022-03-01 R-HSA-9705683 SARS-CoV-2-host interactions BibTex
2019-06-03 R-HSA-9645460 Alpha-protein kinase 1 signaling pathway BibTex
2017-02-28 R-HSA-8953854 Metabolism of RNA BibTex
2016-02-02 R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic BibTex
2016-02-02 R-HSA-6811438 Intra-Golgi traffic BibTex
2016-02-02 R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network BibTex
2016-02-02 R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic BibTex
2016-02-02 R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic BibTex
2016-02-02 R-HSA-8856688 Golgi-to-ER retrograde transport BibTex
2015-09-02 R-HSA-6807878 COPI-mediated anterograde transport BibTex
2015-08-18 R-HSA-5694530 Cargo concentration in the ER BibTex
2015-03-12 R-HSA-5626978 TNFR1-mediated ceramide production BibTex
2015-03-12 R-HSA-5357956 TNFR1-induced NF-kappa-B signaling pathway BibTex
2015-03-12 R-HSA-5357905 Regulation of TNFR1 signaling BibTex
2015-02-06 R-HSA-73942 DNA Damage Reversal BibTex
2015-02-06 R-HSA-73943 Reversal of alkylation damage by DNA dioxygenases BibTex
2015-02-06 R-HSA-112126 ALKBH3 mediated reversal of alkylation damage BibTex
2015-02-06 R-HSA-112122 ALKBH2 mediated reversal of alkylation damage BibTex
2015-02-06 R-HSA-5657655 MGMT-mediated DNA damage reversal BibTex
2015-02-06 R-HSA-5357769 Caspase activation via extrinsic apoptotic signalling pathway BibTex
2014-10-31 R-HSA-5218859 Regulated Necrosis BibTex
2014-10-31 R-HSA-5213460 RIPK1-mediated regulated necrosis BibTex
2014-10-31 R-HSA-5218900 CASP8 activity is inhibited BibTex
2014-10-31 R-HSA-5357786 TNFR1-induced proapoptotic signaling BibTex
2012-11-19 R-HSA-140534 Caspase activation via Death Receptors in the presence of ligand BibTex
2012-11-19 R-HSA-69416 Dimerization of procaspase-8 BibTex
2012-02-09 R-HSA-1679131 Trafficking and processing of endosomal TLR BibTex
2011-02-10 R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade BibTex
2011-02-10 R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade BibTex
2011-02-10 R-HSA-975871 MyD88 cascade initiated on plasma membrane BibTex
2010-11-30 R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade BibTex
2010-11-30 R-HSA-166166 MyD88-independent TLR4 cascade BibTex
2010-11-30 R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane BibTex
2010-11-30 R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex BibTex
2010-11-30 R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 BibTex
2010-11-30 R-HSA-166020 Transfer of LPS from LBP carrier to CD14 BibTex
2010-11-30 R-HSA-937039 IRAK1 recruits IKK complex BibTex
2010-11-30 R-HSA-937042 IRAK2 mediated activation of TAK1 complex BibTex
2010-11-30 R-HSA-936964 Activation of IRF3, IRF7 mediated by TBK1, IKK? (IKBKE) BibTex
2010-11-30 R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex BibTex
2010-11-30 R-HSA-937041 IKK complex recruitment mediated by RIP1 BibTex
2010-11-30 R-HSA-937061 TRIF (TICAM1)-mediated TLR4 signaling BibTex
2010-10-29 R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade BibTex
2010-10-29 R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade BibTex
2010-10-29 R-HSA-975155 MyD88 dependent cascade initiated on endosome BibTex
2010-10-29 R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling BibTex
2010-10-29 R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation BibTex
2010-10-29 R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation BibTex
2010-02-28 R-HSA-450294 MAP kinase activation BibTex
2010-02-28 R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases BibTex
2010-02-28 R-HSA-450341 Activation of the AP-1 family of transcription factors BibTex
2010-02-28 R-HSA-450302 activated TAK1 mediates p38 MAPK activation BibTex
2010-02-28 R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 BibTex
2010-02-28 R-HSA-445989 TAK1-dependent IKK and NF-kappa-B activation BibTex
2009-06-02 R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion BibTex
2009-06-02 R-HSA-399997 Acetylcholine regulates insulin secretion BibTex
2008-12-02 R-HSA-264876 Insulin processing BibTex
2008-12-02 R-HSA-381119 Unfolded Protein Response (UPR) BibTex
2008-12-02 R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones BibTex
2008-12-02 R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes BibTex
2008-12-02 R-HSA-381070 IRE1alpha activates chaperones BibTex
2008-12-02 R-HSA-381038 XBP1(S) activates chaperone genes BibTex
2008-12-02 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) BibTex
2008-12-02 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane BibTex
2008-12-02 R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress BibTex
2008-12-02 R-HSA-381042 PERK regulates gene expression BibTex
2007-02-03 R-HSA-8978868 Fatty acid metabolism BibTex
2007-02-03 R-HSA-8979227 Triglyceride metabolism BibTex
2007-02-03 R-HSA-163560 Triglyceride catabolism BibTex
2007-02-03 R-HSA-75109 Triglyceride biosynthesis BibTex
Reviewed Reactions (397/397)
Date Identifier Reaction Reference
2022-05-10 R-HSA-9758486 Unknown kinase phosphorylates 9b BibTex
2022-05-10 R-HSA-9727293 6 localizes to the nuclear envelope BibTex
2022-05-10 R-HSA-9755354 8 forms a homodimer BibTex
2022-05-10 R-HSA-9727305 mRNA8 is translated to protein 8 BibTex
2022-05-10 R-HSA-9727292 mRNA6 is translated to protein 6 BibTex
2022-05-10 R-HSA-9727300 9b homodimer localizes to the mitochondrial outer membrane BibTex
2022-05-10 R-HSA-9727284 9b forms a homodimer BibTex
2022-05-10 R-HSA-9727303 mRNA9 is translated to protein 9b BibTex
2022-05-10 R-HSA-9727288 7a localizes to the ERGIC membrane BibTex
2022-05-10 R-HSA-9727297 mRNA7 is translated to protein 7a BibTex
2022-05-10 R-HSA-9770187 S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion BibTex
2022-05-10 R-HSA-9770063 S1,S2 Dissociate from S1:ACE2:S2 BibTex
2022-05-10 R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage BibTex
2022-05-10 R-HSA-9733495 Viral Spike Binds to ACE2 on Uninfected Cell BibTex
2022-05-10 R-HSA-9769812 Spike Trimer Translocates to the Plasma Membrane BibTex
2022-05-10 R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs BibTex
2020-01-03 R-HSA-174447 RFC dissociates after sliding clamp formation on the C-strand of the telomere BibTex
2020-01-03 R-HSA-174452 RFC binding displaces Pol Alpha on the C-strand of the telomere BibTex
2020-01-03 R-HSA-163096 Recruitment of Telomerase RNP to the Telomeric Chromosome End BibTex
2019-06-03 R-HSA-9645442 Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex BibTex
2019-06-03 R-HSA-9645406 ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) BibTex
2019-06-03 R-HSA-9645394 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation BibTex
2019-06-03 R-HSA-9645414 Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer BibTex
2019-06-03 R-HSA-9645501 TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex BibTex
2019-06-03 R-HSA-9645520 ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 BibTex
2019-06-03 R-HSA-9645481 TIFA oligomerization BibTex
2019-06-03 R-HSA-9645535 ALPK1 phosphorylates TIFA BibTex
2019-06-03 R-HSA-9645524 ALPK1:ADP-heptose binds TIFA BibTex
2019-06-03 R-HSA-9645428 ALPK1 binds ADP-heptose BibTex
2018-07-28 R-RNO-9614351 Unblocking of Grin1:Grin2 NMDA receptors BibTex
2018-07-28 R-RNO-9614350 Glycine and glutamate ligands bind Grin1:Grin2a NMDA receptor BibTex
2018-07-28 R-HSA-9614185 Mg2+ binds GRIN1:GRIN2 NMDA receptors BibTex
2018-07-28 R-RNO-9614228 Mg2+ binds Grin1:Grin2 NMDA receptors BibTex
2016-02-02 R-HSA-6811433 The COG tethering complex interacts with numerous SNAREs at the Golgi membrane BibTex
2016-02-02 R-HSA-8847883 CYTH proteins stimulate ARF1 GTPase activity BibTex
2016-02-02 R-HSA-8847880 CYTH proteins bind ARF1:GTP BibTex
2016-02-02 R-HSA-8847887 RAB33B:GTP binds RIC1:RGP1 BibTex
2016-02-02 R-HSA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN BibTex
2016-02-02 R-HSA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange BibTex
2016-02-02 R-HSA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles BibTex
2016-02-02 R-SCE-6814089 NatC acetylates ARL3 BibTex
2016-02-02 R-HSA-6814090 NatC acetylates ARFFRP1 BibTex
2016-02-02 R-HSA-6814088 SYS1 binds AcM-ARFRP1 BibTex
2016-02-02 R-HSA-6814086 ARFRP1 recruits ARL1 to the TGN BibTex
2016-02-02 R-HSA-6814675 RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN BibTex
2016-02-02 R-HSA-6814670 ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation BibTex
2016-02-02 R-HSA-6814674 Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins BibTex
2016-02-02 R-HSA-6814671 Fusion of late-endosome derived vesicles at the TGN BibTex
2016-02-02 R-HSA-6814094 ARL1:GTP binds ARFIP2 BibTex
2016-02-02 R-HSA-8847537 RAB43:GTP binds USP8NL BibTex
2016-02-02 R-HSA-8847534 RAB43 hydrolyses GTP BibTex
2016-02-02 R-HSA-6814091 ARL1 recruits TGN Golgin homodimers BibTex
2016-02-02 R-HSA-6814676 SNAPs and NSF hexamer bind cis-SNARE at the TGN BibTex
2016-02-02 R-HSA-6814678 ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN BibTex
2016-02-02 R-HSA-6814096 ARL1:GTP binds SCOC BibTex
2016-02-02 R-HSA-6814682 Fusion of early-endosome derived vesicles at the TGN BibTex
2016-02-02 R-HSA-6814684 cis-SNARE binds SNAPs and NSF hexamer at the TGN BibTex
2016-02-02 R-HSA-6814683 NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN BibTex
2016-02-02 R-HSA-8849348 RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo BibTex
2016-02-02 R-HSA-8849350 RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex BibTex
2016-02-02 R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane BibTex
2016-02-02 R-HSA-8849345 LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine BibTex
2016-02-02 R-HSA-8849353 Dynein drives COPI-independent retrograde traffic from the Golgi to the ER BibTex
2016-02-02 R-HSA-8850040 RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER BibTex
2016-02-02 R-HSA-8850041 RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 BibTex
2016-02-02 R-HSA-6811415 RAB:GTP recruits GBF1 to the Golgi membrane BibTex
2016-02-02 R-HSA-6811411 GBF1 recruits ARF:GDP to the Golgi BibTex
2016-02-02 R-HSA-6811414 GBF1 stimulates nucleotide exchange on ARF BibTex
2016-02-02 R-HSA-6811412 Active ARF recruits coatomer to the Golgi BibTex
2016-02-02 R-HSA-6811417 ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi BibTex
2016-02-02 R-HSA-6811418 ARFGAPs stimulate ARF GTPase activity at the Golgi membrane BibTex
2016-02-02 R-HSA-6811426 Retrograde COPI vesicles bind kinesin and microtubules BibTex
2016-02-02 R-HSA-6811423 Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs BibTex
2016-02-02 R-HSA-6811427 COPI vesicle uncoating at the ER BibTex
2016-02-02 R-HSA-6811425 NSF and SNAPs bind cis-SNARE at the ER membrane BibTex
2016-02-02 R-HSA-6811422 NSF ATPase activity dissociates cis-SNARE at the ER BibTex
2016-02-02 R-HSA-8847544 The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering BibTex
2016-02-02 R-HSA-8847635 Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic BibTex
2016-02-02 R-HSA-8847637 NSF and SNAPs bind the cis-SNARE at the Golgi BibTex
2016-02-02 R-HSA-8847638 ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane BibTex
2016-02-02 R-HSA-8849748 The COG complex binds RABs at the Golgi membrane BibTex
2016-02-02 R-HSA-8847875 ARF1:GTP binds Golgin TRIP11 BibTex
2015-11-25 R-HSA-6814833 TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP BibTex
2015-11-25 R-HSA-6814831 TBC1D20 binds RAB1:GTP BibTex
2015-09-02 R-HSA-6809015 NSF ATPase activity dissociates cis-SNARE at cis-Golgi BibTex
2015-09-02 R-HSA-6809014 cis-Golgi cis-SNARE binds NSF and SNAPs BibTex
2015-09-02 R-HSA-6809010 COPI vesicle uncoating BibTex
2015-09-02 R-HSA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle BibTex
2015-09-02 R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex BibTex
2015-09-02 R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin BibTex
2015-09-02 R-HSA-6807877 ARFGAPs stimulate ARF GTPase activity BibTex
2015-09-02 R-HSA-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex BibTex
2015-09-02 R-HSA-6807872 Active ARF recruits coatomer BibTex
2015-09-02 R-HSA-6807868 GBF1 stimulates ARF nucleotide exchange BibTex
2015-09-02 R-HSA-6807866 GBF1 recruits ARF:GDP to the ERGIC BibTex
2015-09-02 R-HSA-6807864 RAB1:GTP recruits GBF1 to the ERGIC BibTex
2015-08-18 R-HSA-5694425 NSF ATPase activity dissociates cis-SNARE BibTex
2015-08-18 R-HSA-5694421 PP6 dephosphorylates SEC24 BibTex
2015-08-18 R-HSA-5694423 NSF and SNAPs bind cis-SNARE complex BibTex
2015-08-18 R-HSA-5694446 BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle BibTex
2015-08-18 R-HSA-5694441 CSNK1D phosphorylates SEC23 BibTex
2015-08-18 R-HSA-5694418 RAB1:GTP binds USO1 and GORASP1:GOLGA2 BibTex
2015-08-18 R-HSA-5694409 Nucleotide exchange on RAB1 BibTex
2015-08-18 R-HSA-5694439 COPII coat binds TRAPPCII and RAB1:GDP BibTex
2015-08-18 R-HSA-5694417 SEC16 complex binds SAR1B:GTP:SEC23:SEC24 BibTex
2015-08-18 R-HSA-5694427 MIA3 binds procollagen VII BibTex
2015-08-18 R-HSA-5694522 Inner coat assembly and cargo binding BibTex
2015-08-18 R-HSA-5694410 TMED2:TMED10 tetramer binds GPI anchored proteins BibTex
2015-08-18 R-HSA-5694442 CNIH2,3 bind GRIA1 BibTex
2015-08-18 R-HSA-5694445 CNIH1 binds TFGA and AREG precursors BibTex
2015-08-18 R-HSA-5694413 SEC4C,D bind GOSR2 and STX5 BibTex
2015-08-18 R-HSA-5694428 LMAN family proteins bind glycosylated cargo BibTex
2015-08-18 R-HSA-5694431 Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors BibTex
2015-08-18 R-HSA-5694415 SEC24A,B:SEC23A bind SEC22B BibTex
2015-08-18 R-HSA-5694433 MIA2 binds PREB BibTex
2015-08-18 R-HSA-5694435 MIA2 and MIA3 load procollagen VII into COPII vesicles BibTex
2015-08-18 R-HSA-5694436 MIA2 and MIA3 dissociate from procollagen VII vesicle BibTex
2015-03-12 R-HSA-5626981 TNF-?:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 BibTex
2015-03-12 R-HSA-5626982 TNF-?:TNFR1:NSMAF binds GNB2L1 BibTex
2015-03-12 R-HSA-5626988 TNF-?:TNFR1 binds NSMAF BibTex
2015-03-12 R-HSA-5357860 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex BibTex
2015-03-12 R-HSA-5357776 TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG BibTex
2015-03-12 R-HSA-5357928 CLIP3 and CYLD bind TNF signaling complex BibTex
2015-03-12 R-HSA-5634221 TRAF1 binds TRAF2 within TNFR1 signaling complex BibTex
2015-03-12 R-HSA-5634228 TRAF1 is cleaved by caspases BibTex
2015-03-12 R-HSA-5626953 TNF-?:TNFR1 binds DENN/MADD BibTex
2015-03-12 R-HSA-5661517 LUBAC binds OTULIN BibTex
2015-03-12 R-HSA-5357831 CHUK, IKBKB phosphorylate CYLD at S418 BibTex
2015-03-12 R-HSA-5692550 Viral inhibitor of caspase-8 activation (UL36) binds caspase-8 BibTex
2015-03-12 R-HSA-5626962 GNB2L1 binds IKKA:IKKB:NEMO BibTex
2015-03-12 R-HSA-5357904 TNF:TNFR1:TRADD:TRAF2:RIPK1 binds LUBAC BibTex
2015-03-12 R-HSA-5357845 K63polyUb-RIPK1 is deubiquitinated BibTex
2015-03-12 R-HSA-5357757 BIRC(cIAP1/2) ubiquitinates RIPK1 BibTex
2015-03-12 R-HSA-5357780 TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) BibTex
2015-03-12 R-HSA-5357828 RIPK1 is cleaved by CASP8 BibTex
2015-02-06 R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 BibTex
2015-02-06 R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 BibTex
2015-02-06 R-HSA-5657642 ALKBH3 in complex with ASCC1:ASCC2:ASCC3 binds alkylated DNA containing 1-etA BibTex
2015-02-06 R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 BibTex
2015-02-06 R-HSA-5657617 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 3-meC BibTex
2015-02-06 R-HSA-5657637 ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 1-meA BibTex
2015-02-06 R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 BibTex
2015-02-06 R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 BibTex
2015-02-06 R-HSA-5657649 ALKBH2 binds alkylated DNA containing 1-etA BibTex
2015-02-06 R-HSA-5657665 ALKBH2 binds alkylated dsDNA containing 3-meC BibTex
2015-02-06 R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 BibTex
2015-02-06 R-HSA-5657641 ALKBH2 binds alkylated DNA containing 1-meA BibTex
2015-02-06 R-HSA-73892 MGMT/hAGT mediated DNA Damage Reversal BibTex
2015-02-06 R-HSA-5657651 MGMT binds alkylated DNA containing 6-O-methylguanine BibTex
2014-10-31 R-HSA-5213462 RIPK3 binds RIPK1 BibTex
2014-10-31 R-HSA-5213466 RIPK3 is phosphorylated BibTex
2014-10-31 R-HSA-5213464 RIPK1 is phosphorylated BibTex
2014-10-31 R-HSA-5218905 RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils BibTex
2014-10-31 R-HSA-5218891 RIPK1:RIPK3 oligomer binds MLKL BibTex
2014-10-31 R-HSA-5218906 RIPK3 phosphorylates MLKL BibTex
2014-10-31 R-HSA-5357927 MLKL oligomerizes BibTex
2014-10-31 R-HSA-5620975 MLKL binds PIPs BibTex
2012-12-20 R-HSA-202724 P-selectin binds P-selectin ligand BibTex
2012-12-20 R-HSA-2870221 E-selectin binds E-selectin ligand BibTex
2012-11-19 R-HSA-351863 Translocation of active caspase-8 to the mitochondrial membrane BibTex
2012-11-19 R-HSA-139952 Caspase-8 processing in the DISC BibTex
2012-11-19 R-HSA-73945 FAS-mediated dimerization of procaspase-8 BibTex
2012-11-19 R-HSA-141156 TRAIL-mediated dimerization of procaspase-8 BibTex
2012-11-19 R-HSA-141159 TNF-mediated dimerization of procaspase-8 BibTex
2012-02-09 R-HSA-1679589 Engulfed CpG DNA binds to endosomal full-length TLR9 BibTex
2012-02-09 R-HSA-1679098 Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer BibTex
2012-02-09 R-HSA-1678981 TLR9 processing at neutral pH BibTex
2012-02-09 R-HSA-1678920 TLR processing at low pH BibTex
2012-02-09 R-HSA-1678927 UNC93B1 delivers endosomal full-length TLRs to endolysosome BibTex
2012-02-09 R-HSA-1678998 Endosomal TLRs pass through the Golgi BibTex
2012-02-09 R-HSA-1678921 Full-length TLR3/7/8/9 binds to UNC93B1 BibTex
2012-02-09 R-HSA-1678944 Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex BibTex
2012-02-09 R-HSA-1678923 TLR folding by chaperones GP96 and CNPY3 BibTex
2011-02-10 R-HSA-975879 Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex BibTex
2011-02-10 R-HSA-975857 TRAF6 binds to hp- IRAK1 or p-IRAK2 BibTex
2011-02-10 R-HSA-975861 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex BibTex
2011-02-10 R-HSA-975853 Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR BibTex
2011-02-10 R-HSA-975874 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex BibTex
2011-02-10 R-HSA-975878 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR BibTex
2011-02-10 R-HSA-975852 IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex BibTex
2011-02-10 R-HSA-975865 IRAK4 autophosphorylation within the complex activated TLR:MyD88 BibTex
2011-02-10 R-HSA-975873 IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor BibTex
2011-02-10 R-HSA-975880 MyD88 oligomerization within the complex of activated TLR:MyD88 BibTex
2011-02-10 R-HSA-975866 MyD88 forms a complex with the activated TLR receptor BibTex
2011-02-10 R-HSA-188025 Flagellin binds to TLR5 BibTex
2011-02-10 R-HSA-168947 Ligand binds to TLR10 BibTex
2010-11-30 R-HSA-9014342 K63-linked ubiquitination of RIP1 bound to the activated TLR complex BibTex
2010-11-30 R-HSA-9014343 IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex BibTex
2010-11-30 R-HSA-9013978 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex BibTex
2010-11-30 R-HSA-9013979 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 BibTex
2010-11-30 R-HSA-166168 TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) BibTex
2010-11-30 R-HSA-2262775 Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex BibTex
2010-11-30 R-HSA-2559464 TLR6/2 ligand associates with CD14 and CD36 within lipid rafts BibTex
2010-11-30 R-HSA-168950 TLR6:TLR2 is recruited to ligand:CD14:CD36 BibTex
2010-11-30 R-HSA-168951 TLR1:TLR2 is recruited to ligand:CD14 BibTex
2010-11-30 R-HSA-166015 Association of LBP with LPS BibTex
2010-11-30 R-HSA-166038 GPI-bound CD14 binds LPS BibTex
2010-11-30 R-HSA-169719 Secreted CD14 binds LPS BibTex
2010-11-30 R-HSA-166041 Transfer of LPS onto TLR4 BibTex
2010-11-30 R-HSA-166072 MyD88 forms a complex with TIRAP:activated TLR2/4 BibTex
2010-11-30 R-HSA-937079 MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 BibTex
2010-11-30 R-HSA-166082 IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex BibTex
2010-11-30 R-HSA-937022 IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP BibTex
2010-11-30 R-HSA-166091 IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex BibTex
2010-11-30 R-HSA-166119 First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal BibTex
2010-11-30 R-HSA-166284 Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP BibTex
2010-11-30 R-HSA-166286 Multiple IRAK1 autophosphorylation steps BibTex
2010-11-30 R-HSA-166363 TRAF6 binds to hp- IRAK1 BibTex
2010-11-30 R-HSA-166362 Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex BibTex
2010-11-30 R-HSA-936963 IRAK2 induces TRAF6 oligomerization BibTex
2010-11-30 R-HSA-936942 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 BibTex
2010-11-30 R-HSA-936986 Activated TRAF6 synthesizes unanchored polyubiquitin chains BibTex
2010-11-30 R-HSA-936960 Activated TRAF6:p-IRAK2 interacts with TAK1 complex BibTex
2010-11-30 R-HSA-936991 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 BibTex
2010-11-30 R-HSA-166175 TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) BibTex
2010-11-30 R-HSA-936985 Activated TLR4:TICAM1 recruits TRAF6 BibTex
2010-11-30 R-HSA-936952 Auto ubiquitination of TRAF6 bound to the activated TLR4 complex BibTex
2010-11-30 R-HSA-936947 Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex BibTex
2010-11-30 R-HSA-936951 Activation of TAK1 complex bound to activated TLR4 complex BibTex
2010-11-30 R-HSA-937044 Pellino binds hp-IRAK1:TRAF6 BibTex
2010-11-30 R-HSA-937034 IRAK1 phosphorylates Pellino BibTex
2010-11-30 R-HSA-937050 Pellino ubiquitinates hp-IRAK1 BibTex
2010-11-30 R-HSA-937032 NEMO subunit of IKK complex binds to activated IRAK1 BibTex
2010-11-30 R-HSA-168921 TRIF:activated TLR3/TLR4 complex recruits RIP1 BibTex
2010-11-30 R-HSA-166869 TRAF6 binds MEKK1 BibTex
2010-11-30 R-HSA-166271 IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 BibTex
2010-11-30 R-HSA-166245 Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex BibTex
2010-11-30 R-HSA-168933 Dimerization of phosphorylated IRF3/IRF7 BibTex
2010-11-30 R-HSA-177671 Dimerized phospho-IRF3/IRF7 is transported to the nucleus BibTex
2010-11-30 R-HSA-937075 Phosphorylated TAK1 leaves activated TLR receptor complex BibTex
2010-11-30 R-HSA-168915 K63-linked ubiquitination of RIP1 bound to the activated TLR complex BibTex
2010-11-30 R-HSA-937029 IKBKG subunit of IKK complex binds polyubiquinated RIP1 BibTex
2010-11-30 R-HSA-937059 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex BibTex
2010-11-30 R-HSA-2262777 TRAF6 binds to p-IRAK2 BibTex
2010-11-24 R-HSA-109864 Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 BibTex
2010-11-24 R-HSA-109863 Dissociation of p-T,Y-MAPK3:MAP2K1 BibTex
2010-10-29 R-HSA-975118 TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex BibTex
2010-10-29 R-HSA-975103 Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975097 Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation BibTex
2010-10-29 R-HSA-975119 NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. BibTex
2010-10-29 R-HSA-975122 Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
 		BibTex
2010-10-29 R-HSA-975139 IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975142 Pellino binds hp-IRAK1:TRAF6 upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975147 Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane BibTex
2010-10-29 R-HSA-975185 IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments BibTex
2010-10-29 R-HSA-975100 Dissociation of hp-IRAK1/or IRAK2:TRAF6-oligomer from the p-IRAK4 :oligo-Myd88:activated TLR7/8 or 9 complex BibTex
2010-10-29 R-HSA-975106 Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975188 TRAF6 interacts with IRF7 upon TLR7/8 or 9 activation BibTex
2010-10-29 R-HSA-975111 TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9 BibTex
2010-10-29 R-HSA-975125 Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 BibTex
2010-10-29 R-HSA-975134 Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 BibTex
2010-10-29 R-HSA-975180 First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 BibTex
2010-10-29 R-HSA-975160 Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 BibTex
2010-10-29 R-HSA-975115 IRAK1/or IRAK2 binds to the activated IRAK4 :MyD88:activated TLR 7/8 or 9. BibTex
2010-10-29 R-HSA-975170 IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 BibTex
2010-10-29 R-HSA-975156 IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex BibTex
2010-10-29 R-HSA-975098 MyD88 oligomerization within the complex of activated TLR 7/8 or 9 : MyD88 BibTex
2010-10-29 R-HSA-975175 MyD88 interacts with the activated TLR receptor 7, 8 or 9 BibTex
2010-05-28 R-HSA-847070 Phosphorylated TAK1 dissociates from the TLR3 receptor complex BibTex
2010-03-02 R-HSA-450358 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation BibTex
2010-03-02 R-HSA-9628444 Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation BibTex
2010-03-02 R-HSA-450259 Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex BibTex
2010-02-28 R-HSA-450257 Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 BibTex
2010-02-28 R-HSA-450222 Active p38 MAPK phosphorylates MAPKAPK2 or 3 BibTex
2010-02-28 R-HSA-450325 c-FOS activation by phospho ERK1/2 BibTex
2010-02-28 R-HSA-450333 Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 BibTex
2010-02-28 R-HSA-450296 Phosphorylated MKK3/MKK6 migrates to nucleus BibTex
2010-02-28 R-HSA-450346 activated human TAK1 phosphorylates MKK3/MKK6 BibTex
2010-02-28 R-HSA-450348 Activated human JNKs migrate to nucleoplasm BibTex
2010-02-28 R-HSA-450337 Activated TAK1 phosphorylates MKK4/MKK7 BibTex
2009-06-02 R-HSA-265645 Calcium Influx through Voltage-gated Calcium Channels BibTex
2009-06-02 R-HSA-381727 RAP1A exchanges GDP for GTP BibTex
2009-06-02 R-HSA-381608 cAMP activates EPAC2 BibTex
2009-06-02 R-HSA-381644 ER calcium channels open in response to activated PKA BibTex
2009-06-02 R-HSA-381713 Potassium voltage-gated channels close in reponse to PKA BibTex
2009-06-02 R-HSA-381668 cAMP activates EPAC1 BibTex
2009-06-02 R-HSA-265682 KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel BibTex
2009-06-02 R-HSA-381707 PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP BibTex
2009-06-02 R-HSA-381607 Activated Adenylyl cyclase synthesizes cyclic AMP BibTex
2009-06-02 R-HSA-381704 G(s):GTP activates Adenylyl cyclase BibTex
2009-06-02 R-HSA-381706 GLP1R:GLP1 activates G(s) BibTex
2009-06-02 R-HSA-381612 GLP1R binds GLP1 BibTex
2009-06-02 R-HSA-399978 Protein kinase C, alpha type phosphorylates MARCKS BibTex
2009-06-02 R-HSA-265166 Exocytosis of Insulin BibTex
2009-06-02 R-HSA-400015 Diacylgycerol activates Protein kinase C, alpha type BibTex
2009-06-02 R-HSA-169683 IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol BibTex
2009-06-02 R-HSA-169680 IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel BibTex
2009-06-02 R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate BibTex
2009-06-02 R-HSA-400023 Gq alpha activates Phospholipase C beta BibTex
2009-06-02 R-HSA-400027 Gq alpha:G beta:G gamma dissociates to Gq alpha:GTP and G beta:G gamma BibTex
2009-06-02 R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq BibTex
2009-06-02 R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 BibTex
2008-12-02 R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) BibTex
2008-12-02 R-NUL-9023186 Carboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87)) BibTex
2008-12-02 R-HSA-9023173 Insulin secretory granule docks at the plasma membrane BibTex
2008-12-02 R-HSA-9023171 Insulin secretory granule translocates across the cortical actin network BibTex
2008-12-02 R-HSA-265160 Insulin secretory granule translocates to cell cortex BibTex
2008-12-02 R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) BibTex
2008-12-02 R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) BibTex
2008-12-02 R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) BibTex
2008-12-02 R-NUL-9023166 Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54) BibTex
2008-12-02 R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) BibTex
2008-12-02 R-MMU-216806 Processing of Proinsulin to Insulin BibTex
2008-12-02 R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) BibTex
2008-12-02 R-HSA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule BibTex
2008-12-02 R-HSA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium BibTex
2008-12-02 R-HSA-265010 Proinsulin translocates from the endoplasmic reticulum to the Golgi BibTex
2008-12-02 R-HSA-264997 P4HB mediates disulfide bond formation in Proinsulin BibTex
2008-12-02 R-HSA-1791121 Expression of XBP1(S) BibTex
2008-12-02 R-HSA-1791150 Expression of BIP (78 kDa Glucose-regulated protein, GRP78, HSPA5) BibTex
2008-12-02 R-HSA-1791082 Expression of Calreticulin BibTex
2008-12-02 R-HSA-1791163 Expression of HSP90B1 (Endoplasmin) BibTex
2008-12-02 R-HSA-1791076 Expression of ADD1 (Adducin alpha) BibTex
2008-12-02 R-HSA-1791143 Expression of YIF1A BibTex
2008-12-02 R-HSA-1791137 Expression of Talin-1 BibTex
2008-12-02 R-HSA-1791138 Expression of TPP1 BibTex
2008-12-02 R-HSA-1791139 Expression of SRPR (SRP Receptor subunit alpha) BibTex
2008-12-02 R-HSA-1791075 Expression of DNAJB11 BibTex
2008-12-02 R-HSA-1791084 Expression of SYVN1 (HRD1) BibTex
2008-12-02 R-HSA-1791144 Expression of EXTL3 BibTex
2008-12-02 R-HSA-1791083 Expression of Sec12 BibTex
2008-12-02 R-HSA-1791156 Expression of TATDN2 BibTex
2008-12-02 R-HSA-1791092 Expression of DCTN1 BibTex
2008-12-02 R-HSA-1791157 Expression of DNAJC3 (p58IPK) BibTex
2008-12-02 R-HSA-1791158 Expression of CXXC1 BibTex
2008-12-02 R-HSA-1791088 Expression of GFPT1 BibTex
2008-12-02 R-HSA-1791154 Expression of GOSR2 BibTex
2008-12-02 R-HSA-1791155 Expression of EDEM BibTex
2008-12-02 R-HSA-1791164 Expression of SSR1 (Trap alpha) BibTex
2008-12-02 R-HSA-1791102 Expression of C19orf10 BibTex
2008-12-02 R-HSA-1791167 Expression of SERP1 (RAMP4) BibTex
2008-12-02 R-HSA-1791096 Expression of PPP2R5B BibTex
2008-12-02 R-HSA-1791172 Expression of WIPI1 BibTex
2008-12-02 R-HSA-1791108 Expression of SULT1A3 BibTex
2008-12-02 R-HSA-1791169 Expression of WFS1 BibTex
2008-12-02 R-HSA-1791116 Expression of DDX11 BibTex
2008-12-02 R-HSA-1791054 Expression of GSK3A BibTex
2008-12-02 R-HSA-1791112 Expression of HDGF BibTex
2008-12-02 R-HSA-1791177 Expression of KLHDC3 BibTex
2008-12-02 R-HSA-1791114 Expression of FKBP14 BibTex
2008-12-02 R-HSA-1791060 Expression of SRPRB (SRP Receptor subunit beta) BibTex
2008-12-02 R-HSA-1791124 Expression of DNAJB9 BibTex
2008-12-02 R-HSA-1791184 Expression of ATP6VOD1 BibTex
2008-12-02 R-HSA-1791057 Expression of TSPYL2 BibTex
2008-12-02 R-HSA-1791186 Expression of ZBTB17 BibTex
2008-12-02 R-HSA-1791122 Expression of PDIA5 BibTex
2008-12-02 R-HSA-1791058 Expression of Cullin-7 BibTex
2008-12-02 R-HSA-1791123 Expression of KDELR3 BibTex
2008-12-02 R-HSA-1791133 Expression of Sec31A BibTex
2008-12-02 R-HSA-1791069 Expression of ACADVL BibTex
2008-12-02 R-HSA-1791134 Expression of SHC1 BibTex
2008-12-02 R-HSA-1791071 Expression of PLA2G4B BibTex
2008-12-02 R-HSA-1791128 Expression of LMNA BibTex
2008-12-02 R-HSA-1791064 Expression of ARFGAP1 (GAP) BibTex
2008-12-02 R-HSA-1791066 Expression of HYOU1 BibTex
2008-12-02 R-HSA-1791130 Expression of CTDSP2 BibTex
2008-12-02 R-HSA-381412 IGFBP2 binds IGF forming IGF:IGFBP2 BibTex
2008-12-02 R-HSA-381543 IGFBP4 binds IGF forming IGF:IGFBP4 BibTex
2008-12-02 R-HSA-381496 Formation of the IGF:IGFBP3:ALS complex BibTex
2008-12-02 R-HSA-381446 Thrombin proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381545 Formation of the IGF:IGFBP5:ALS complex BibTex
2008-12-02 R-HSA-381537 PAPP-A2 proteolyzes IGF:IGFBP5:ALS BibTex
2008-12-02 R-HSA-381487 IGFBP1 binds IGF forming IGF:IGFBP1 BibTex
2008-12-02 R-HSA-381518 PAAP-A proteolyzes IGF:IGFBP4 BibTex
2008-12-02 R-HSA-381461 Plasmin proteolyzes IGF:IGFBP-3:ALS BibTex
2008-12-02 R-HSA-381500 Cathepsin G proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381503 IGFBP6 binds IGF forming IGF:IGFBP6 BibTex
2008-12-02 R-HSA-381435 Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-381466 Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS BibTex
2008-12-02 R-HSA-1799335 Synthesis of nascent polypeptide containing signal sequence BibTex
2008-12-02 R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) BibTex
2008-12-02 R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex BibTex
2008-12-02 R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum BibTex
2008-12-02 R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein BibTex
2008-12-02 R-HSA-381086 Dissociation of PERK:BiP Heterodimer BibTex
2008-12-02 R-HSA-381087 Dimerization of PERK BibTex
2008-12-02 R-HSA-381111 EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK BibTex
2008-12-02 R-HSA-381128 Translation of ATF4 BibTex
2008-12-02 R-HSA-1791118 Expression of ASNS (Asparagine Synthetase) BibTex
2008-12-02 R-HSA-1791173 Expression of ATF3 BibTex
2008-12-02 R-HSA-381158 ATF6:HSPA5 (ATF6-alpha:BiP) dissociates and HSPA5 binds unfolded protein BibTex
2008-12-02 R-HSA-381186 ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi BibTex
2008-12-02 R-HSA-381135 MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) BibTex
2008-12-02 R-HSA-420818 MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) BibTex
2008-12-02 R-HSA-381026 ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus BibTex
2008-12-02 R-HSA-517731 Expression of IL-8 BibTex
2008-12-02 R-HSA-1791180 Expression of IGFBP1 BibTex
2008-12-02 R-HSA-1791107 Expression of DDIT3 (CHOP, GADD153) in response to unfolded protein BibTex
2008-12-02 R-HSA-1791056 Expression of CCL2 BibTex
2008-12-02 R-HSA-1791095 Expression of HERPUD BibTex
2008-12-02 R-HSA-381217 IRE1:BiP dissociates in response to unfolded protein BibTex
2008-12-02 R-HSA-381109 IRE1 binds IRE1 forming dimer BibTex
2008-12-02 R-HSA-381091 IRE1 dimer autophosphorylates BibTex
2008-12-02 R-HSA-381116 Phosphorylated IRE1 dimer binds ADP BibTex
2008-12-02 R-HSA-425923 IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced BibTex
2008-12-02 R-HSA-381203 XBP(S) mRNA is translated and XBP1(S) translocates to the nucleus BibTex
2008-12-02 R-HSA-1791131 Expression of PDIA6 (Protein disulfide-isomerase A6) BibTex
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