Sisira Kadambat Nair

 ORCID
https://orcid.org/0000-0003-0693-9994
Affiliation
Princess Margaret Cancer Centre, Princess Margaret Hospital
Reviewed Pathways (5/5)
Date Identifier Pathway Reference
2021-11-02 R-HSA-9754119 Drug-mediated inhibition of CDK4/CDK6 activity BibTex
2021-08-05 R-HSA-9734091 Drug-mediated inhibition of MET activation BibTex
2021-07-28 R-HSA-9729902 Reversible DNA damage induced by alkylating chemotherapeutic drugs BibTex
2021-07-28 R-HSA-9730737 Alkylating DNA damage induced by chemotherapeutic drugs BibTex
2021-07-28 R-HSA-9750126 Drug-induced formation of DNA interstrand crosslinks BibTex
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Reviewed Reactions (15/20)
Date Identifier Reaction Reference
2021-11-02 R-HSA-9754130 CDK4 inhibitors bind CDK4 BibTex
2021-11-02 R-HSA-9754129 CDK6 inhibitors bind CDK6 BibTex
2021-11-02 R-HSA-69227 Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes BibTex
2021-08-05 R-HSA-9735946 Anti-MET small tyrosine kinase inhibitors bind MET BibTex
2021-08-05 R-HSA-9734070 Anti-MET recombinant therapeutic antibodies bind MET BibTex
2021-08-05 R-HSA-6806974 MET dimers autophosphorylate BibTex
2021-08-05 R-HSA-6800298 HGF dimer binds MET BibTex
2021-07-28 R-HSA-9732692 Triazenes produce DNA damage in the form of O6-methylguanine BibTex
2021-07-28 R-MMU-9749883 Temozolomide produces DNA damage in the form of O6-methylguanine in mouse dsDNA BibTex
2021-07-28 R-HSA-9730767 Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA BibTex
2021-07-28 R-RNO-9730905 Streptozocin (streptozotocin) produces 7-methylguanine in dsDNA BibTex
2021-07-28 R-RNO-9730878 Procarbazine produces 7-methylguanine in dsDNA BibTex
2021-07-28 R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA BibTex
2021-07-28 R-RNO-9730898 Streptozocin (streptozotocin) produces 3-methyladenine in dsDNA BibTex
2021-07-28 R-HSA-9713785 Anti-cancer drugs generate DNA interstrand crosslinks BibTex
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