Jim Woodgett

 ORCID
https://orcid.org/0000-0003-3731-5797
Reviewed Pathways (15/21)
Date Identifier Pathway Reference
2014-05-12 R-HSA-4791275 Signaling by WNT in cancer BibTex
2014-05-12 R-HSA-4839735 AXIN mutants destabilize the destruction complex, activating WNT signaling BibTex
2014-05-12 R-HSA-5467340 AXIN missense mutants destabilize the destruction complex BibTex
2014-05-12 R-HSA-5467345 Deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling BibTex
2014-05-12 R-HSA-5340588 RNF mutants show enhanced WNT signaling and proliferation BibTex
2014-05-12 R-HSA-4839748 AMER1 mutants destabilize the destruction complex BibTex
2014-05-12 R-HSA-5467343 Deletions in the AMER1 gene destabilize the destruction complex BibTex
2014-05-12 R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex BibTex
2014-05-12 R-HSA-5340573 WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 BibTex
2014-05-12 R-HSA-4839744 truncated APC mutants destabilize the destruction complex BibTex
2014-05-12 R-HSA-5467337 APC truncation mutants have impaired AXIN binding BibTex
2014-05-12 R-HSA-5467333 APC truncation mutants are not K63 polyubiquitinated BibTex
2014-05-12 R-HSA-5545619 XAV939 inhibits tankyrase, stabilizing AXIN BibTex
2014-05-12 R-HSA-4839743 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex BibTex
2014-05-12 R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated BibTex
Reviewed Reactions (15/20)
Date Identifier Reaction Reference
2014-05-12 R-HSA-4839734 AXIN mutants destabilize the destruction complex BibTex
2014-05-12 R-HSA-5251562 Deletions in the AXIN1 gene prevent expression of AXIN1 protein BibTex
2014-05-12 R-HSA-5340587 RNF43 frameshift mutants show enhanced WNT siganling BibTex
2014-05-12 R-HSA-5251559 Deletions of the AMER1 gene prevent expression of AMER1 protein BibTex
2014-05-12 R-HSA-4839746 Truncated AMER1 mutants destabilize the destruction complex BibTex
2014-05-12 R-HSA-5340560 PORCN-inhibitor LGK974 prevents WNT ligand palmitoyltation and secretion BibTex
2014-05-12 R-HSA-4791278 APC truncation mutants have impaired AXIN binding BibTex
2014-05-12 R-HSA-5246696 APC truncation mutants are not K63 polyubiquitinated BibTex
2014-05-12 R-HSA-5262606 XAV939 binds tankyrase to stabilize axin and inhibit WNT signaling BibTex
2014-05-12 R-HSA-4827388 CTNNB1 S45 mutants aren't phosphorylated by CK1alpha BibTex
2014-05-12 R-HSA-4839635 CTNNB1 S37 mutants aren't phosphorylated by GSK3beta BibTex
2014-05-12 R-HSA-4839634 CTNNB1 S33 mutants aren't phosphorylated by GSK3beta BibTex
2014-05-12 R-HSA-4839638 CTNNB1 T41 mutants aren't phosphorylated by GSK3beta BibTex
2014-05-12 R-HSA-5334052 TFC7L2 mutants don't bind CTBP BibTex
2014-05-12 R-HSA-5339713 Misspliced GSK3beta mutants stabilize beta-catenin levels BibTex
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