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Aris Moustakas

Ludwig Institute for Cancer Research
Authored Reactions (37)
Date Identifier Reaction Reference
2007-11-07 R-HSA-201472 The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus BibTex
2007-11-07 R-HSA-201422 Phospho-R-Smad1/5/8 forms a complex with Co-Smad BibTex
2007-11-07 R-HSA-201453 Phospho-R-Smad1/5/8 dissociates from the receptor complex BibTex
2007-11-07 R-HSA-201476 Activated type I receptor phosphorylates R-Smad1/5/8 directly BibTex
2007-11-07 R-HSA-201648 An anchoring protein, Endofin, recruits R-Smad1/5/8 BibTex
2007-11-07 R-HSA-201443 Type II receptor phosphorylates type I receptor BibTex
2007-11-07 R-HSA-201457 BMP2 binds to the receptor complex BibTex
2007-11-07 R-HSA-202604 Formation of a heteromeric BMP receptor complex BibTex
2007-11-07 R-HSA-201810 The ligand trap binds the ligand BMP2, blocking BMP signalling BibTex
2007-11-07 R-HSA-201445 Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 BibTex
2007-11-07 R-HSA-201475 I-Smad competes with R-Smad1/5/8 for type I receptor BibTex
2007-11-07 R-HSA-202626 I-Smad competes with Co-Smad for R-Smad1/5/8 BibTex
2007-11-07 R-HSA-201425 Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling BibTex
2007-11-07 R-HSA-201423 SKI complexes with the Smad complex, suppressing BMP2 signalling BibTex
2007-11-07 R-HSA-201821 I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated BibTex
2006-02-02 R-HSA-173488 The SMAD2/3:SMAD4 complex transfers to the nucleus BibTex
2006-02-02 R-HSA-170847 Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 BibTex
2006-02-02 R-HSA-170850 Phosphorylated SMAD2/3 dissociates from TGFBR BibTex
2006-02-02 R-HSA-170868 Activated type I receptor phosphorylates SMAD2/3 directly BibTex
2006-02-02 R-HSA-170835 An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 BibTex
2006-02-02 R-HSA-170843 TGFBR2 phosphorylates TGFBR1 BibTex
2006-02-02 R-HSA-170846 TGFBR2 recruits TGFBR1 BibTex
2006-02-02 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor BibTex
2006-02-02 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 BibTex
2006-02-02 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin BibTex
2006-02-02 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) BibTex
2006-02-02 R-HSA-173542 SMURF2 ubiquitinates SMAD2 BibTex
2006-02-02 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 BibTex
2006-02-02 R-HSA-178215 SMAD7:SMURF1 complex is exported to the cytosol BibTex
2006-02-02 R-HSA-2167917 SMAD7 binds to SMURF1 BibTex
2006-02-02 R-HSA-178208 SMAD7 binds to SMURF2 BibTex
2006-02-02 R-HSA-178178 PP1 dephosphorylates TGFBR1 BibTex
2006-02-02 R-NUL-2167872 PP1CC dephosphorylates TGFBR1 BibTex
2006-02-02 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR BibTex
2006-02-02 R-NUL-2167890 Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex BibTex
2006-02-02 R-HSA-173545 Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling BibTex
2006-02-02 R-HSA-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling BibTex