Jacek Skowronski

 ORCID
Reviewed Pathways (7/7)
Date Identifier Pathway Reference
2007-08-07 R-HSA-164952 The role of Nef in HIV-1 replication and disease pathogenesis BibTex
2007-08-07 R-HSA-164944 Nef and signal transduction BibTex
2007-08-07 R-HSA-164938 Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters BibTex
2007-08-07 R-HSA-167590 Nef Mediated CD4 Down-regulation BibTex
2007-08-07 R-HSA-182218 Nef Mediated CD8 Down-regulation BibTex
2007-08-07 R-HSA-164939 Nef mediated downregulation of CD28 cell surface expression BibTex
2007-08-07 R-HSA-164940 Nef mediated downregulation of MHC class I complex cell surface expression BibTex
Reviewed Reactions (15/20)
Date Identifier Reaction Reference
2007-08-07 R-HSA-200858 Nef Binds and activates the Src-family tyrosine kinase Hck BibTex
2007-08-07 R-HSA-200954 Nef Binds and activates the Src-family tyrosine kinase Lck BibTex
2007-08-07 R-HSA-200952 Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction BibTex
2007-08-07 R-HSA-164943 Nef mediated activation of the T-cell receptor BibTex
2007-08-07 R-HSA-200908 Nef Binds and activates the Src-family tyrosine kinase Fyn BibTex
2007-08-07 R-HSA-167537 Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-08-07 R-HSA-167566 Nef mediated disruption of CD4:Lck Complex BibTex
2007-08-07 R-HSA-167601 Degradation of CD4 BibTex
2007-08-07 R-HSA-200879 Formation of a Nef:ARF1:CD4 complex BibTex
2007-08-07 R-HSA-167597 Internalization of the CD4:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-08-07 R-HSA-182198 Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-08-07 R-HSA-182186 Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex BibTex
2007-08-07 R-HSA-182171 Degradation of CD8 BibTex
2007-08-07 R-HSA-167633 Formation of Nef:Cd28:Clathrin-coated Pit Adapter Protein complex BibTex
2007-08-07 R-HSA-167630 Formation of Nef CD28 cytoplasmic tail complex BibTex