Castagnoli, L

Authored Pathways (5/5)
Date Identifier Pathway Reference
2008-02-28 R-HSA-177929 Signaling by EGFR BibTex
2006-10-10 R-HSA-180336 SHC1 events in EGFR signaling BibTex
2006-10-10 R-HSA-179812 GRB2 events in EGFR signaling BibTex
2006-10-10 R-HSA-180292 GAB1 signalosome BibTex
2006-10-10 R-HSA-182971 EGFR downregulation BibTex
Authored Reactions (15/41)
Date Identifier Reaction Reference
2006-10-10 R-HSA-177942 EGFR binds EGF ligand BibTex
2006-10-10 R-HSA-177946 Pro-EGF is cleaved to form mature EGF BibTex
2006-10-10 R-HSA-177927 PI3K binds to EGF:EGFR:GRB2:GAB1 BibTex
2006-10-10 R-HSA-177930 GAB1 phosphorylation by EGFR kinase BibTex
2006-10-10 R-HSA-177941 GRB2:GAB1 binds to phosphorylated EGFR BibTex
2006-10-10 R-HSA-179467 GAB1 binds phosphatidylinositol-3,4,5-trisphosphate BibTex
2006-10-10 R-HSA-177939 PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) BibTex
2006-10-10 R-HSA-177920 Binding of GRB2 to GAB1 BibTex
2006-10-10 R-HSA-177934 EGFR autophosphorylation BibTex
2006-10-10 R-HSA-177922 EGFR dimerization BibTex
2006-10-10 R-HSA-177931 Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 BibTex
2006-10-10 R-HSA-177936 GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR BibTex
2006-10-10 R-HSA-177933 SHC1 phosphorylation by phosphorylated EGFR BibTex
2006-10-10 R-HSA-177925 SHC1 binds to the phosphorylated EGF receptor:ligand complex BibTex
2006-10-10 R-HSA-177943 GRB2:SOS1 complex binds to EGF:EGFR complex BibTex
Reviewed Pathways (15/15)
Date Identifier Pathway Reference
2008-11-06 R-HSA-111997 CaM pathway BibTex
2008-11-06 R-HSA-111933 Calmodulin induced events BibTex
2008-11-06 R-HSA-111957 Cam-PDE 1 activation BibTex
2008-11-06 R-HSA-111931 PKA-mediated phosphorylation of CREB BibTex
2008-11-06 R-HSA-163615 PKA activation BibTex
2008-11-06 R-HSA-111932 CaMK IV-mediated phosphorylation of CREB BibTex
2008-11-06 R-HSA-170670 Adenylate cyclase inhibitory pathway BibTex
2008-11-06 R-HSA-111885 Opioid Signalling BibTex
2008-11-06 R-HSA-112040 G-protein mediated events BibTex
2008-11-06 R-HSA-170660 Adenylate cyclase activating pathway BibTex
2008-11-06 R-HSA-112043 PLC beta mediated events BibTex
2008-11-06 R-HSA-111996 Ca-dependent events BibTex
2008-11-06 R-HSA-111995 phospho-PLA2 pathway BibTex
2008-11-06 R-HSA-180024 DARPP-32 events BibTex
2008-11-06 R-HSA-202040 G-protein activation BibTex
Reviewed Reactions (15/54)
Date Identifier Reaction Reference
2008-11-06 R-BTA-74447 Calcium binds calmodulin BibTex
2008-11-06 R-RNO-182097 Calcium release from intracellular stores by IP3 receptor activation BibTex
2008-11-06 R-RNO-182052 IP3 binds to the IP3 receptor, opening the Ca2+ channel BibTex
2008-11-06 R-HSA-111879 PIP2 hydrolysis BibTex
2008-11-06 R-HSA-111870 Activation of PLC beta-1/4 BibTex
2008-11-06 R-HSA-111912 CaMK4 phosphorylates CREB1 BibTex
2008-11-06 R-RNO-379832 CaMKIV phosphorylates Creb1 BibTex
2008-11-06 R-HSA-111915 CAMK4 autophosphorylates BibTex
2008-11-06 R-HSA-111913 Calmodulin binds CAMK4 BibTex
2008-11-06 R-RNO-379960 Calmodulin binds CaMK IV BibTex
2008-11-06 R-HSA-112282 CAMK4 enters the nucleus BibTex
2008-11-06 R-HSA-111881 Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase BibTex
2008-11-06 R-HSA-111898 Phosphorylation of cPLA2 by ERK-2 BibTex
2008-11-06 R-HSA-111916 Dimerization of p-S133-CREB1 BibTex
2008-11-06 R-RNO-379842 Dimerization of p-S133-Creb1 BibTex