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Friedman, WJ

 ORCID
Reviewed Reactions (62)
Date Identifier Reaction Reference
2008-05-20 R-HSA-193705 IKKbeta phosphorylates IkB causing NF-kB to dissociate BibTex
2008-05-20 R-HSA-193703 IKKbeta is activated BibTex
2008-05-20 R-HSA-193641 IKK-beta is recruited BibTex
2008-05-20 R-HSA-193694 p62 is recruited and forms a complex with TRAF6 BibTex
2008-05-20 R-HSA-193665 MYD88 dissociates BibTex
2008-05-20 R-HSA-193695 IRAK interacts with TRAF6 BibTex
2008-05-20 R-HSA-193647 IRAK is activated BibTex
2008-05-20 R-HSA-193686 p75NTR interacts with IRAK:MYD88 BibTex
2008-05-20 R-HSA-193653 NGF homodimer binds to p75NTR BibTex
2008-05-20 R-RNO-193905 p75NTR interacts with Irak:Myd88 BibTex
2008-05-20 R-RNO-193887 Irak is activated BibTex
2008-05-20 R-HSA-193650 p75NTR binds to NADE BibTex
2008-05-20 R-HSA-205117 p75NTR:NADE promotes caspase2/3 activation BibTex
2008-05-20 R-HSA-204981 14-3-3epsilon attentuates NADE-related apoptosis BibTex
2008-05-20 R-HSA-205136 GTP-bound RAC contributes to JNK activation BibTex
2008-05-20 R-HSA-205039 p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor BibTex
2008-05-20 R-HSA-193666 Active JNK moves to the nucleus and phosphorylates different transcription factors BibTex
2008-05-20 R-HSA-193669 TRAF6 binds to p75NTR:NRIF BibTex
2008-05-20 R-HSA-193677 NRIF binds to p75NTR BibTex
2008-05-20 R-MMU-194544 NRIF binds to p75NTR BibTex
2008-05-20 R-HSA-205075 JNK phosphorylates BIM, BAD and other targets BibTex
2008-05-20 R-HSA-205132 NRAGE activates JNK BibTex
2008-05-20 R-HSA-205115 NGF:p75NTR complex binds to NRAGE BibTex
2008-05-20 R-MMU-204967 NGF:p75NTR complex binds to Nrage BibTex
2008-05-20 R-RNO-205027 Nrage activates Jnk1 BibTex
2008-05-20 R-HSA-204958 NRAGE sequesters CHE1 in the cytoplasm BibTex
2008-05-20 R-MMU-205099 Nrage sequesters Che1 in the cytoplasm BibTex
2008-05-20 R-HSA-204947 Polyubiquitinated NRIF migrates to the nucleus BibTex
2008-05-20 R-HSA-205118 TRAF6 polyubiquitinates NRIF BibTex
2008-05-20 R-HSA-205112 gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 BibTex
2008-05-20 R-HSA-205008 Polyubiquitinated NRIF binds to p62 (Sequestosome) BibTex
2008-05-20 R-HSA-204949 NRIF and TRAF6 may activate JNK BibTex
2008-05-20 R-MMU-205060 NRIF and TRAF6 may activate JNK BibTex
2008-05-20 R-HSA-193684 p62 recruits an atypical PKC BibTex
2008-05-20 R-HSA-193656 p75NTR interacts with RIP2 BibTex
2008-05-20 R-HSA-209566 TRAF6 is auto-ubiquitinated BibTex
2008-05-20 R-HSA-209536 IkB is ubiquitinated and degraded BibTex
2008-05-20 R-HSA-193691 NF-kB migrates to the nucleus and turns on transcription BibTex
2008-05-20 R-HSA-193679 alpha-secretase cleaves the p75NTR extracellular domain BibTex
2008-05-20 R-HSA-209532 The p75NTR C-terminal fragment enters endosomes BibTex
2008-05-20 R-HSA-193682 gamma-secretase cleaves the p75NTR transmembrane domain BibTex
2008-05-20 R-HSA-193700 p75NTR ICD signals to NF-kB BibTex
2008-05-20 R-HSA-193702 Part of the ICD migrates to the nucleus BibTex
2008-05-20 R-HSA-193668 p75NTR and RHOA-GDI interact BibTex
2008-05-20 R-HSA-193646 NGF binding to p75NTR inactivates RHOA BibTex
2008-05-20 R-HSA-193636 p75NTR interacts with the NOGO receptor BibTex
2008-05-20 R-HSA-9012761 The p75NTR:NgR:MDGI binds RHOA-GDI BibTex
2008-05-20 R-HSA-193696 The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA BibTex
2008-05-20 R-HSA-209573 p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 BibTex
2008-05-20 R-HSA-193655 Myelin components can interact with p75NTR:NgR:LINGO1 BibTex
2008-05-20 R-HSA-194518 RhoA is activated by nucleotide exchange and inhibits axonal growth BibTex
2008-05-20 R-HSA-193642 Binding of pro-NGF to p75NTR:sortilin BibTex
2008-05-20 R-HSA-193706 Production of ceramide which can activate JNK and other targets BibTex
2008-05-20 R-HSA-193672 Sphingomyelinase is activated by the NGF:p75NTR complex BibTex
2008-05-20 R-RNO-194339 Sphingomyelinase is activated by the NGF:p75NTR complex BibTex
2008-05-20 R-RNO-209562 Production of ceramide which can activate JNK and other targets BibTex
2008-05-20 R-HSA-205056 PRDM4 inhibits cyclin E transcription BibTex
2008-05-20 R-HSA-193661 PRDM4 translocates to the nucleus BibTex
2008-05-20 R-HSA-193643 PRDM4 (SC1) binds to p75NTR BibTex
2008-05-20 R-RNO-194493 Prdm4 (Sc1) binds to p75NTR BibTex
2008-05-20 R-RNO-194578 Prdm4 translocates to the nucleus BibTex
2008-05-20 R-RNO-205010 Prdm4 inhibits cyclin E transcription BibTex
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