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Ezzat, S

 ORCID
Reviewed Reactions (91)
Date Identifier Reaction Reference
2012-05-15 R-HSA-1839100 p-4Y- PLCG1 dissociates from activated FGFR1 mutants and fusions BibTex
2012-05-15 R-HSA-1839098 Activated FGFR1 mutants and fusions phosphorylate PLCG1 BibTex
2012-05-15 R-HSA-1839094 Activated FGFR1 mutants and fusions bind PLCG1 BibTex
2012-05-15 R-HSA-1839065 Phosphorylation of cytosolic FGFR1 fusion dimers BibTex
2012-05-15 R-HSA-1839031 Dimerization of cytosolic FGFR1 fusion proteins BibTex
2012-05-15 R-HSA-5655269 Activated FGFR1 mutants bind FRS2 BibTex
2012-05-15 R-HSA-5655266 Activated FGFR1 mutants:p-FRS2 binds GRB2-SOS1 BibTex
2012-05-15 R-HSA-5655278 Activated FGFR1 mutants phosphorylate FRS2 BibTex
2012-05-15 R-HSA-1839102 BCR-FGFR1 fusion:GRB2:p-GAB2:PIK3R1 binds PIK3CA BibTex
2012-05-15 R-HSA-1839114 BCR-FGFR1:GRB2:p-GAB2 binds PIK3R1 BibTex
2012-05-15 R-HSA-1839110 p-BCR-p-FGFR1 phosphorylates GAB2 BibTex
2012-05-15 R-HSA-1839095 p-BCR-pFGFR1 binds GRB2:GAB2 BibTex
2012-05-15 R-HSA-1839067 Phosphorylation of BCR moiety of BCR-FGFR1 BibTex
2012-05-15 R-HSA-1839039 Tyrosine kinase inhibitors bind and inhibit cytosolic FGFR1 fusion dimer phosphorylation BibTex
2012-05-15 R-HSA-1839091 Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 BibTex
2012-05-15 R-HSA-1839080 Activated cytosolic FGFR1 fusions bind PIK3CA BibTex
2012-05-15 R-HSA-1839078 Cytosolic FGFR1 fusion proteins bind PIK3R1 BibTex
2012-05-15 R-HSA-1839112 Phosphorylation of STAT5 by cytosolic FGFR1 fusions BibTex
2012-05-15 R-HSA-1888198 FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 BibTex
2012-05-15 R-HSA-1839107 BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. BibTex
2012-05-15 R-HSA-5654544 Ligand-independent dimerization of overexpressed FGFR1c BibTex
2012-05-15 R-HSA-5654545 Ligand-independent phosphorylation of overexpressed FGFR1c BibTex
2012-05-15 R-HSA-2023462 Tyrosine kinase inhibitors bind and inhibit overexpressed FGFR1 dimers BibTex
2012-05-15 R-HSA-1982065 Ligand-independent dimerization of overexpressed FGFR1b BibTex
2012-05-15 R-HSA-1982066 Ligand-independent phosphorylation of overexpressed FGFR1 BibTex
2012-05-15 R-HSA-2023455 Autocatalytic phosphorylation of FGFR1c P252X mutant dimers BibTex
2012-05-15 R-HSA-2023451 FGFR1c P252X mutants bind ligand with enhanced affinity BibTex
2012-05-15 R-HSA-2023460 Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2023456 Dimerization of FGFR1 point mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-5655326 Activated FGFR1 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange BibTex
2012-05-15 R-HSA-5655263 Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA BibTex
2012-05-15 R-HSA-5655240 Activated FGFR1 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 BibTex
2012-05-15 R-HSA-5655290 Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 BibTex
2012-05-15 R-HSA-5655270 Activated FGFR3 mutants phosphorylate FRS2 BibTex
2012-05-15 R-HSA-5655285 Activated FGFR3 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA BibTex
2012-05-15 R-HSA-2077420 FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors BibTex
2012-05-15 R-HSA-2038387 Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants BibTex
2012-05-15 R-HSA-2038386 Dimerization of FGFR3 t(4;14) translocation mutants BibTex
2012-05-15 R-HSA-2033485 Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2033476 Dimerization of FGFR3 point mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2012074 FGFR3c P250R mutant binds to ligand with enhanced affinity BibTex
2012-05-15 R-HSA-2012073 Autocatalytic phosphorylation of FGFR3c P250R mutant BibTex
2012-05-15 R-HSA-2012084 Constitutive dimerization of FGFR3 cysteine mutants BibTex
2012-05-15 R-HSA-2012082 Autocatalytic phosphorylation of FGFR3 cysteine mutants BibTex
2012-05-15 R-HSA-5655315 Activated FGFR3 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 BibTex
2012-05-15 R-HSA-5655262 Activated FGFR3 mutants bind FRS2 BibTex
2012-05-15 R-HSA-5655295 Activated FGFR3 mutants:p-FRS2 binds GRB2-SOS1 BibTex
2012-05-15 R-HSA-5655247 p-4Y-PLCG1 dissociates from activated FGFR3 mutants BibTex
2012-05-15 R-HSA-5655243 Activated FGFR3 mutants phosphorylate PLCG1 BibTex
2012-05-15 R-HSA-5655244 Activated FGFR3 mutants bind PLCG1 BibTex
2012-05-15 R-HSA-5655277 Activated FGFR3 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange BibTex
2012-05-15 R-HSA-5655289 Activated FGFR3 mutant-associated PI3K phosphorylates PIP2 to PIP3 BibTex
2012-05-15 R-HSA-5655268 Activated FGFR2 mutants phosphorylate FRS2 BibTex
2012-05-15 R-HSA-5655301 Activated FGFR2 mutants phosphorylate PLCG1 BibTex
2012-05-15 R-HSA-5655233 Activated FGFR2 mutants:p-FRS2 binds GRB2-SOS1 BibTex
2012-05-15 R-HSA-5655343 Activated FGFR2 mutants bind PLCG1 BibTex
2012-05-15 R-HSA-2029983 Dimerization of FGFR2 ligand-independent mutants BibTex
2012-05-15 R-HSA-2033486 Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding BibTex
2012-05-15 R-HSA-2033472 FGFR2c mutants bind an expanded range of ligands BibTex
2012-05-15 R-HSA-2077421 FP-1039 acts as a ligand-trap for FGFR2b-binding ligands in endometrial cancer BibTex
2012-05-15 R-HSA-2033479 Dimerization of FGFR2 point mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2033474 FGFR2b mutants bind an expanded range of ligands BibTex
2012-05-15 R-HSA-2033490 Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2029984 Autocatalytic phosphorylation of FGFR2 ligand-independent mutants BibTex
2012-05-15 R-HSA-2033488 Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding BibTex
2012-05-15 R-HSA-2077424 Point mutants of FGFR2 bind and are inactivated by tyrosine kinase inhibitors BibTex
2012-05-15 R-HSA-2029992 Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants BibTex
2012-05-15 R-HSA-2029988 Dimerization of overexpressed FGFR2 BibTex
2012-05-15 R-HSA-2029989 Autocatalytic phosphorylation of overexpressed FGFR2 variants BibTex
2012-05-15 R-HSA-2067713 GP369 inhibits activation of amplified FGFR2 signaling BibTex
2012-05-15 R-HSA-5654748 p-4Y-PLCG1 dissociates from activated FGFR2 mutants BibTex
2012-05-15 R-HSA-5655245 Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA BibTex
2012-05-15 R-HSA-5655339 Activated FGFR2 mutants bind FRS2 BibTex
2012-05-15 R-HSA-5655323 Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 BibTex
2012-05-15 R-HSA-5655320 Activated FGFR2 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 BibTex
2012-05-15 R-HSA-5655241 Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange BibTex
2012-05-15 R-HSA-5655351 Activated FGFR4 mutants bind FRS2 BibTex
2012-05-15 R-HSA-5655284 Activated FGFR4 mutants phosphorylate FRS2 BibTex
2012-05-15 R-HSA-5655348 Activated FGFR4 mutants:p-FRS2 binds GRB2-SOS1 BibTex
2012-05-15 R-HSA-5655252 Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA BibTex
2012-05-15 R-HSA-2046363 FGFR4 kinase mutants are inhibited by PD170734 BibTex
2012-05-15 R-HSA-2038946 Dimerization of FGFR4 mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-2012086 Constitutive dimerization of FGFR4 Y367C mutant BibTex
2012-05-15 R-HSA-2012087 Autocatalytic phosphorylation of FGFR4 Y367C mutant BibTex
2012-05-15 R-HSA-2038944 Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity BibTex
2012-05-15 R-HSA-5655347 Activated FGFR4 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange BibTex
2012-05-15 R-HSA-5655235 Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 BibTex
2012-05-15 R-HSA-5655248 Activated FGFR4 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 BibTex
2012-05-15 R-HSA-5655313 Activated FGFR4 mutants bind PLCG1 BibTex
2012-05-15 R-HSA-5655341 Activated FGFR4 mutants phosphorylate PLCG1 BibTex
2012-05-15 R-HSA-5655336 p-4Y-PLCG1 dissociates from activated FGFR4 mutants BibTex