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2012-05-14
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R-HSA-173488
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The SMAD2/3:SMAD4 complex transfers to the nucleus
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2012-05-14
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R-HSA-170847
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Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4
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2012-05-14
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R-HSA-170850
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Phosphorylated SMAD2/3 dissociates from TGFBR
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2012-05-14
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R-HSA-170868
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Activated type I receptor phosphorylates SMAD2/3 directly
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2012-05-14
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R-HSA-170835
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An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3
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2012-05-14
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R-HSA-170843
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TGFBR2 phosphorylates TGFBR1
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2012-05-14
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R-HSA-170846
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TGFBR2 recruits TGFBR1
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2012-05-14
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R-HSA-170861
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Dimeric TGF-beta-1 binds to the receptor
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2012-05-14
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R-HSA-870437
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USP9X (FAM) deubiquitinates SMAD4
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2012-05-14
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R-HSA-870479
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USP9X (FAM) binds to ubiquitinated SMAD4
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2012-05-14
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R-HSA-870477
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Ubiquitinated SMAD4 translocates from the nucleus to the cytosol
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2012-05-14
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R-HSA-870449
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TRIM33 monoubiquitinates SMAD4
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2012-05-14
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R-HSA-870538
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TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus
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2012-05-14
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R-HSA-2186747
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Ubiquitination of SKI/SKIL by RNF111/SMURF2
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2012-05-14
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R-HSA-2186741
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SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL
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2012-05-14
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R-HSA-173481
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SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling
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2012-05-14
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R-NUL-2186736
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Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation
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2012-05-14
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R-HSA-2179276
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SMURF2 monoubiquitinates SMAD3
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2012-05-14
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R-HSA-2179274
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SMURF2 binds SMAD3 phosphorylated in the linker region
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2012-05-14
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R-HSA-2176475
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Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9
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BibTex
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2012-05-14
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R-HSA-2186785
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RNF111 ubiquitinates SMAD7
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2012-05-14
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R-HSA-2186771
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RNF111 binds SMAD7
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2012-05-14
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R-HSA-2106591
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WWTR1:SMAD stimulates transcription of SMAD7
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2012-05-14
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R-HSA-9736970
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WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter
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2012-05-14
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R-HSA-2106579
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WWTR1:SMAD translocates to the nucleus
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2012-05-14
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R-HSA-2031355
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WWTR1 binds SMAD2/3:SMAD4 heterotrimer
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2012-05-14
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R-NUL-2186775
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Rnf111 ubiquitinates Smad7
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BibTex
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2012-05-14
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R-NUL-2186755
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Ubiquitination of SKI/SKIL by Rnf111
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2012-05-14
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R-HSA-1484099
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MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex
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BibTex
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2012-05-14
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R-HSA-9736984
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p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter
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BibTex
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2012-05-14
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R-HSA-2127257
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SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2
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BibTex
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2012-05-14
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R-HSA-2187303
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SMAD2/3:SMAD4:SP1 complex stimulates transcription of CDKN2B
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2012-05-14
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R-HSA-9736979
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p-2S-SMAD2,3:SMAD4:SP1 binds CDKN2B gene promoter
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2012-05-14
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R-HSA-2187309
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SMAD2/3:SMAD4 heterotrimer binds SP1
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2012-05-14
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R-HSA-2176491
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NEDD4L binds phosphorylated linker region of SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2176502
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NEDD4L ubiquitinates SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2186607
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TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer
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BibTex
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2012-05-14
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R-HSA-9736966
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SMAD7 binds SERPINE1 gene promoter
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2012-05-14
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R-HSA-2176503
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Degradation of SMAD2/3:SMAD4 complex
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2012-05-14
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R-HSA-2187325
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PARP1 ADP-ribosylates SMAD3 and SMAD4
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2012-05-14
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R-HSA-2187330
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PARP1 binds SMAD2/3:SMAD4 heterotrimer
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2012-05-14
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R-HSA-209055
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PPM1A dephosphorylates nuclear SMAD2/3
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2012-05-14
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R-HSA-2187388
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PPM1A protein phosphatase binds phosphorylated SMAD2/3
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2012-05-14
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R-HSA-2187395
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Dephosphorylated SMAD2/3 translocates to the cytosol
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2012-05-14
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R-HSA-173545
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Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling
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BibTex
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2012-05-14
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R-HSA-2186767
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Degradation of ubiquitinated SKI/SKIL
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BibTex
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2012-05-14
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R-HSA-9736959
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WWTR1:p-2S-SMAD2,3:SMAD4 binds SERPINE1 gene promoter
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BibTex
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2012-05-14
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R-HSA-2186643
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MEN1 binds SMAD2/3:SMAD4 heterotrimer
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2012-05-14
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R-HSA-9736992
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p-2S-SMAD2,3:SMAD4 binds JUNB gene promoter
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BibTex
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2012-05-14
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R-HSA-2106586
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WWTR1:SMAD stimulates transcription of SERPINE1 while TGIF:SMAD and SMAD7 inhibit it
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2012-05-14
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R-HSA-2187293
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SMAD2/3:SMAD4 complex positively regulates JUNB transcription
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BibTex
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2012-05-14
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R-HSA-2186780
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Degradation of Ub-SMAD7
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BibTex
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2012-05-14
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R-HSA-177107
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Secretion and activation of the latent large complex of TGF-beta-1
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BibTex
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2012-05-14
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R-HSA-170844
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Latent TGF-beta-1 is cleaved by FURIN
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BibTex
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2012-05-14
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R-HSA-178178
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PP1 dephosphorylates TGFBR1
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2012-05-14
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R-HSA-178189
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SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR
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BibTex
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2012-05-14
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R-HSA-173512
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I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1)
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BibTex
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2012-05-14
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R-NUL-2167890
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Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex
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BibTex
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2012-05-14
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R-NUL-2167872
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PP1CC dephosphorylates TGFBR1
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BibTex
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2012-05-14
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R-HSA-2176417
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SMAD7:NEDD4L complex translocates to the cytosol
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BibTex
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2012-05-14
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R-HSA-2176416
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NEDD4L ubiquitin ligase binds SMAD7
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BibTex
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2012-05-14
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R-NUL-2176430
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NEDD4L binds Smad7
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BibTex
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2012-05-14
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R-NUL-2176428
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Translocation of Smad7:NEDD4L complex to the cytosol
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BibTex
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2012-05-14
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R-HSA-2128994
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STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7
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BibTex
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2012-05-14
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R-HSA-2127562
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STRAP binds phosphorylated TGF-beta receptor complex
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BibTex
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2012-05-14
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R-NUL-2128982
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Strap binds phosphorylated TGF-beta receptor complex
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BibTex
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2012-05-14
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R-HSA-2187368
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STUB1 (CHIP) ubiquitinates SMAD3
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BibTex
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2012-05-14
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R-HSA-2187375
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SMAD3 binds STUB1 (CHIP)
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BibTex
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2012-05-14
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R-HSA-2167917
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SMAD7 binds to SMURF1
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BibTex
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2012-05-14
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R-NUL-2169004
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Smad7 binds SMURF1
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BibTex
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2012-05-14
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R-HSA-2167924
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SMAD7:SMURF1 complex binds XPO1 (CRM1)
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BibTex
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2012-05-14
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R-NUL-2169012
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Smad7:SMURF1 complex binds XPO1 (CRM1)
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BibTex
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2012-05-14
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R-HSA-2187382
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Degradation of ubiquitinated SMAD3
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BibTex
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2012-05-14
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R-HSA-2176445
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SMURF2 binds SMAD2
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BibTex
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2012-05-14
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R-HSA-178208
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SMAD7 binds to SMURF2
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BibTex
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2012-05-14
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R-HSA-173542
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SMURF2 ubiquitinates SMAD2
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BibTex
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2012-05-14
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R-HSA-2167876
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SMAD7:SMURF2 complex translocates to the cytosol
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BibTex
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2012-05-14
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R-NUL-2167888
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Smad7:SMURF2 complex translocates to the cytosol
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BibTex
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2012-05-14
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R-HSA-178215
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SMAD7:SMURF1 complex is exported to the cytosol
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BibTex
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2012-05-14
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R-NUL-2169016
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Smad7:SMURF1 complex translocates to the cytosol
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BibTex
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2012-05-14
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R-HSA-2176452
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Degradation of ubiquitinated SMAD2
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BibTex
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2012-05-14
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R-HSA-178218
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SMAD7:SMURF complex binds to phosphorylated TGFBR1
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BibTex
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2012-05-14
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R-NUL-2169043
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Smad7:SMURF2 binds phosphorylated TGFBR1
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BibTex
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2012-05-14
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R-NUL-2169036
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Smad7:SMURF1 binds phosphorylated TGFBR1
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BibTex
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2012-05-14
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R-NUL-2176431
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Smad7 recruits NEDD4L to activated TGF-beta receptor complex
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BibTex
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2012-05-14
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R-HSA-2187401
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MTMR4 dephosphorylates SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2187405
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MTMR4 binds phosphorylated SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2169046
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Degradation of TGF-beta receptor complex
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BibTex
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2012-05-14
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R-HSA-2169050
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SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7
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BibTex
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2012-05-14
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R-NUL-2176393
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SMURF2 ubiquitinates Smad7 and phosphorylated TGFBR1
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BibTex
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2012-05-14
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R-NUL-2176427
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NEDD4L ubiquitinates Smad7 and TGFBR1
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BibTex
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2012-05-14
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R-NUL-2176396
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SMURF1 ubiquitinates Smad7 and phosphorylated TGFBR1
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BibTex
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2012-05-14
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R-HSA-2179291
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UCHL5, USP15 deubiquitinate TGFBR1
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BibTex
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2012-05-14
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R-HSA-2179293
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UCHL5 binds SMAD7 in complex with ubiquitinated TGFBR1
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BibTex
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2012-05-14
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R-NUL-2179307
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Uchl5 is recruited to TGF-beta receptor complex through Smad7
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BibTex
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2012-05-14
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R-NUL-2179313
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Uchl5 deubiquitinates TGFBR1
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BibTex
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2012-05-14
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R-HSA-2187355
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PMEPA1 sequesters phosphorylated SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2187358
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PMEPA1 sequesters unphosphorylated SMAD2/3
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BibTex
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2012-05-14
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R-HSA-2160931
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Disassembly of tight junctions
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BibTex
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2012-05-14
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R-HSA-2160935
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SMURF1 ubiquitinates RHOA
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BibTex
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2012-05-14
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R-HSA-2160932
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SMURF1 binds phosphorylated PARD6A
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BibTex
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2012-05-14
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R-HSA-2134532
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TGFBR2 phosphorylates TGFBR1 and PARD6A
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BibTex
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2012-05-14
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R-HSA-2134519
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TGFBR2 is recruited to tight junctions after TGF-beta stimulation
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BibTex
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2012-05-14
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R-HSA-2134506
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TGFBR1 is recruited to tight junctions by PARD6A
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BibTex
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2012-05-14
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R-NUL-2161147
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TGFBR1 is recruited to tight junction by binding Pard6a
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BibTex
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2012-05-14
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R-NUL-2161160
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TGFBR2 is recruited to tight junctions-associated, Pard6a-bound, TGFBR1 after TGF-beta stimulation
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BibTex
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2012-05-14
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R-NUL-2161165
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TGFBR2 phosphorylates Pard6a
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BibTex
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