Jean J Zhao

Dana-Farber Cancer Institute, Harvard Medical School
Reviewed Pathways (6/6)
Date Identifier Pathway Reference
2007-11-08 R-HSA-1257604 PIP3 activates AKT signaling BibTex
2007-11-08 R-HSA-199418 Negative regulation of the PI3K/AKT network BibTex
2012-08-13 R-HSA-2219528 PI3K/AKT Signaling in Cancer BibTex
2012-08-13 R-HSA-5674404 PTEN Loss of Function in Cancer BibTex
2012-08-13 R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer BibTex
2012-08-13 R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer BibTex
Reviewed Reactions (15/34)
Date Identifier Reaction Reference
2007-11-08 R-HSA-198270 PDPK1 phosphorylates AKT at T308 BibTex
2012-08-13 R-HSA-2317314 AKT binds PDPK1 BibTex
2007-11-08 R-HSA-2316429 PIP3 recruits PDPK1 to the membrane BibTex
2012-08-13 R-HSA-2316434 PI3K phosphorylates PIP2 to PIP3 BibTex
2007-11-08 R-HSA-199456 PTEN dephosphorylates PIP3 BibTex
2012-08-13 R-HSA-2321904 PTEN mRNA translation negatively regulated by microRNAs BibTex
2012-08-13 R-HSA-2318752 miR-26A microRNAs bind PTEN mRNA BibTex
2012-08-13 R-HSA-8944497 PTEN mRNA translation is negatively regulated by microRNAs BibTex
2007-11-08 R-HSA-198640 TORC2 (mTOR) phosphorylates AKT at S473 BibTex
2007-11-08 R-HSA-2317332 PIP3 recruits AKT to the membrane BibTex
2012-08-13 R-HSA-2219524 PDPK1 binds PIP2 BibTex
2007-11-08 R-HSA-199443 THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation BibTex
2007-11-08 R-HSA-199425 PHLPP dephosphorylates S473 in AKT BibTex
2012-08-13 R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 BibTex
2012-08-13 R-HSA-2243938 AKT1 E17K mutant is phosphorylated by TORC2 complex BibTex
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