Leonardo Salmena

 ORCID
Authored Pathways (6/6)
Date Identifier Pathway Reference
2016-08-11 R-HSA-6807070 PTEN Regulation BibTex
2016-08-11 R-HSA-8943723 Regulation of PTEN mRNA translation BibTex
2016-08-11 R-HSA-8948700 Competing endogenous RNAs (ceRNAs) regulate PTEN translation BibTex
2016-08-11 R-HSA-8948747 Regulation of PTEN localization BibTex
2016-08-11 R-HSA-8943724 Regulation of PTEN gene transcription BibTex
2016-08-11 R-HSA-8948751 Regulation of PTEN stability and activity BibTex
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Authored Reactions (15/35)
Date Identifier Reaction Reference
2016-08-11 R-HSA-8944104 PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN BibTex
2016-08-11 R-HSA-8943817 MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter BibTex
2016-08-11 R-HSA-8943811 MECOM (EVI1) binds the PTEN gene promoter BibTex
2016-08-11 R-HSA-6807077 NR2E1 associated with transcription repressors binds PTEN promoter BibTex
2016-08-11 R-HSA-8944026 SNAI1,SNAI2 bind the PTEN gene promoter BibTex
2016-08-11 R-HSA-8944397 p-T69,T71-ATF2 binds PTEN gene promoter BibTex
2016-08-11 R-HSA-8944078 EGR1 binds the PTEN gene promoter BibTex
2016-08-11 R-HSA-8944047 JUN binds the PTEN gene promoter BibTex
2016-08-11 R-HSA-8944099 Activated PPARG binds PTEN gene promoter BibTex
2016-08-11 R-HSA-8943780 SALL4 recruits NuRD to PTEN gene BibTex
2016-08-11 R-HSA-8943728 SALL4 binds the PTEN gene promoter BibTex
2016-08-11 R-HSA-8944420 MAF1 binds the PTEN gene promoter BibTex
2016-08-11 R-HSA-8944457 MAF1 translocates to the nucleus BibTex
2016-08-11 R-HSA-8944454 mTORC1 phosphorylates MAF1 BibTex
2016-08-11 R-HSA-8944497 PTEN mRNA translation is negatively regulated by microRNAs BibTex
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Reviewed Reactions (15/15)
Date Identifier Reaction Reference
2016-08-11 R-HSA-2318752 miR-26A microRNAs bind PTEN mRNA BibTex
2016-08-11 R-HSA-5632939 TP53 binds the PTEN promoter BibTex
2016-08-11 R-HSA-6807126 Deubiquitinated PTEN translocates to the cytosol BibTex
2016-08-11 R-HSA-6807118 USP7 deubiquitinates monoubiquitinated PTEN BibTex
2016-08-11 R-HSA-6807105 Monoubiquitinated PTEN translocates to the nucleus BibTex
2016-08-11 R-HSA-6807106 PTEN undergoes monoubiquitination BibTex
2016-08-11 R-HSA-6807206 USP13 and OTUD3 deubiquitinate PTEN BibTex
2016-08-11 R-HSA-6807134 NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN BibTex
2016-08-11 R-HSA-8851011 TRIM27 polyubiquitinates PTEN BibTex
2016-08-11 R-HSA-8850997 TRIM27 binds PTEN BibTex
2016-08-11 R-HSA-8850945 Casein kinase II phosphorylates PTEN BibTex
2016-08-11 R-HSA-8847968 PTEN binds FRK BibTex
2016-08-11 R-HSA-8847977 FRK phosphorylates PTEN BibTex
2016-08-11 R-HSA-8850961 PREX2 binds PTEN and inhibits it BibTex
2016-08-11 R-HSA-8850992 Proteasome degrades polyubiquitinated PTEN BibTex
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