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G Gopinathrao

 ORCID
Affiliation
Cold Spring Harbor Laboratory
Authored Reactions (222)
Date Identifier Reaction Reference
2008-11-23 R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix BibTex
2008-11-23 R-HSA-382613 PEX-19 docks ABCD1/D2/D3 to peroximal membrane BibTex
2008-11-23 R-HSA-1369052 ABCAs mediate lipid influx BibTex
2008-11-23 R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux BibTex
2008-11-23 R-HSA-383190 HCO3- transport through ion channel BibTex
2008-11-23 R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport BibTex
2008-11-19 R-HSA-381500 Cathepsin G proteolyzes IGF:IGFBP3:ALS BibTex
2008-11-19 R-MMU-216883 Exocytosis of Insulin BibTex
2008-11-19 R-HSA-264997 Oxidation of cysteine to cystine in Proinsulin BibTex
2008-11-19 R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein BibTex
2008-11-19 R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum BibTex
2008-11-19 R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex BibTex
2008-11-19 R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) BibTex
2008-11-19 R-HSA-1799335 Synthesis of nascent polypeptide containing signal sequence BibTex
2008-11-19 R-HSA-265153 Proinsulin:Zinc:Calcium complex translocates to immature secretory granule BibTex
2008-11-19 R-HSA-264976 Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium BibTex
2008-11-19 R-HSA-265010 Cystine-bonded Proinsulin translocates from the endoplasmic reticulum to the Golgi BibTex
2008-11-19 R-MMU-9023194 Insulin secretory granules dock at the plasma membrane BibTex
2008-11-19 R-MMU-216852 Insulin secretory granule translocates to cell cortex BibTex
2008-11-19 R-HSA-265177 Exocyst complex formation BibTex
2008-05-21 R-HSA-350598 Arginine<=>Agmatine+CO2 BibTex
2008-05-21 R-HSA-350604 Agmatine + H2O <=> putrescine + urea BibTex
2008-05-21 R-HSA-351222 S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 BibTex
2008-05-21 R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met BibTex
2008-05-21 R-HSA-70692 ornithine => putrescine + CO2 BibTex
2008-05-21 R-HSA-351207 Spermine => N-acetylated spermine BibTex
2008-05-21 R-HSA-351201 N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal) BibTex
2008-05-21 R-HSA-351208 Spermidine => N-acetylated spermidine BibTex
2008-05-21 R-HSA-141351 PAOX:FAD oxidises NASPN to SPM BibTex
2008-05-21 R-HSA-351229 N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) BibTex
2008-05-21 R-HSA-141348 PAO:FAD oxidises NASPM to PTCN BibTex
2008-05-21 R-HSA-141341 SMOX-3 oxidises SPN to SPM BibTex
2008-05-21 R-HSA-351215 Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine BibTex
2008-05-21 R-HSA-351210 dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine BibTex
2008-05-19 R-HSA-353125 26S proteosome degrades ODC holoenzyme complex BibTex
2008-05-19 R-HSA-350567 Antizyme OAZ binds to Ornithine decarboxylase BibTex
2008-05-19 R-HSA-350578 NQO1 interaction with ODC BibTex
2008-05-19 R-HSA-350600 Antizyme inhibitor binds to OAZ and stablizes ODC complex BibTex
2008-02-08 R-HSA-212263 PRC2 trimethylates histone H3 at lysine-27 BibTex
2008-02-08 R-HSA-212252 Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin BibTex
2008-02-08 R-HSA-212222 PRC2 recruits DNA methyltransferases BibTex
2008-02-08 R-HSA-212269 DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 BibTex
2007-11-26 R-HSA-204169 PDP dephosphorylates p-lipo-PDH BibTex
2007-11-26 R-HSA-203946 PDK isoforms phosphorylate lipo-PDH BibTex
2007-11-18 R-HSA-9023912 AGO2 cleaves passenger strand of duplex siRNA BibTex
2007-11-18 R-HSA-9023909 C3PO hydrolyzes cleaved passenger strand BibTex
2007-11-18 R-HSA-203922 Exportin-5 recognizes 3' overhang of pre-miRNA BibTex
2007-11-18 R-HSA-203893 Microprocessor complex cleaves pri-miRNA to pre-miRNA BibTex
2007-11-18 R-HSA-203901 Pol II mediated transcription of microRNA genes BibTex
2007-11-18 R-HSA-203906 Exportin complex translocates pre-miRNA to cytosol BibTex
2007-11-18 R-HSA-203862 Dicer cleaves pre-miRNA to yield duplex miRNA BibTex
2007-11-18 R-HSA-210805 Removal of miRNA passenger strand BibTex
2007-07-29 R-HSA-200421 Activation of cytosolic AMPK by phosphorylation BibTex
2007-07-29 R-HSA-200410 palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine BibTex
2007-07-29 R-HSA-200424 Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane BibTex
2007-07-29 R-HSA-200406 CPT1A,B transfers PALM to CAR BibTex
2007-07-29 R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA BibTex
2007-07-29 R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis BibTex
2007-07-29 R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA BibTex
2006-10-13 R-HSA-188467 Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) BibTex
2006-06-15 R-HSA-5228941 Transcytosis and dissociation of BoNT/E:NTNHA BibTex
2006-06-15 R-HSA-194800 BoNT/E LC cleaves target cell SNAP25 BibTex
2006-06-15 R-HSA-5244506 BoNT/E HC transports BoNT/E LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-5244500 BoNT/E:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5244503 BoNT/E HC:LC binds SV2A or B and GT1b on the target cell surface BibTex
2006-06-15 R-HSA-5250880 BoNT/F HC:LC binds SV2A or B or C and GT1b on the target cell surface BibTex
2006-06-15 R-HSA-5250884 BoNT/F HC transports BoNT/F LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-5250875 BoNT/F:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-194808 BoNT/F LC cleaves target cell VAMP1 BibTex
2006-06-15 R-HSA-5250892 BoNT/F LC cleaves target cell VAMP2 BibTex
2006-06-15 R-HSA-5228943 Transcytosis and dissociation of BoNT/A:NTNHA:HA BibTex
2006-06-15 R-HSA-194818 BoNT/A LC cleaves target cell SNAP25 BibTex
2006-06-15 R-HSA-5244428 BoNT/A HC transports BoNT/A LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-5244424 BoNT/A:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5244415 BoNT/A HC:LC binds SV2A, B, or C and GT1b on the target cell surface BibTex
2006-06-15 R-HSA-5246514 BoNT/C HC transports BoNT/C LC from target cell synaptic vesicle membrane to cytosol BibTex
2006-06-15 R-HSA-5246509 BoNT/C:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5246506 BoNT/C HC:LC binds GT1b on the target cell surface BibTex
2006-06-15 R-HSA-194793 BoNT/C LC cleaves target cell SNAP25 BibTex
2006-06-15 R-HSA-181567 BoNT/C LC cleaves target cell STX1 BibTex
2006-06-15 R-HSA-5250600 BoNT/D:SV2:GD2 internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5250607 BoNT/D HC:LC binds SV2A or B or C and GD2 on the target cell surface BibTex
2006-06-15 R-HSA-5250616 BoNT/D HC transports BoNT/D LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-194809 BoNT/D LC cleaves target cell VAMP1 BibTex
2006-06-15 R-HSA-5250606 BoNT/D LC cleaves target cell VAMP2 BibTex
2006-06-15 R-HSA-5250978 BoNT/G LC cleaves target cell VAMP1 BibTex
2006-06-15 R-HSA-5250972 BoNT/G HC transports BoNT/G LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-5250979 BoNT/G:SYT1:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5250986 BoNT/G HC:LC binds SYT1 and GT1b on the target cell surface BibTex
2006-06-15 R-HSA-5250962 BoNT/G LC cleaves target cell VAMP2 BibTex
2006-06-15 R-HSA-5244402 BoNT/B:SYT:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane BibTex
2006-06-15 R-HSA-5244397 BoNT/B HC:LC binds SYT1 or 2 and GT1b on the target cell surface BibTex
2006-06-15 R-HSA-5228940 Transcytosis and dissociation of BoNT/B:NTNHA:HA BibTex
2006-06-15 R-HSA-5244404 BoNT/B HC transports BoNT/B LC from target cell synaptic vesicle membrane into cytosol BibTex
2006-06-15 R-HSA-194796 BoNT/B LC cleaves target cell VAMP2 BibTex
2006-05-18 R-HSA-164514 Integrase binds viral DNA ends BibTex
2006-05-18 R-HSA-173115 Formation of Pre-Integration Complex (PIC) BibTex
2006-05-18 R-HSA-8951690 Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 BibTex
2006-05-18 R-HSA-182876 Removal of plus-strand flap and gap closure complete synthesis of linear duplex viral DNA BibTex
2006-05-18 R-HSA-164505 Synthesis of full-length duplex viral DNA with a discontinuous plus strand BibTex
2006-05-18 R-HSA-164512 Second strand transfer by annealing complementary PBS sequences BibTex
2006-05-18 R-HSA-173769 RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers BibTex
2006-05-18 R-HSA-164513 3' PPT-primed initiation of plus-strand DNA synthesis BibTex
2006-05-18 R-HSA-182795 RNase H-mediated degradation of the template strand BibTex
2006-05-18 R-HSA-164528 RNase H-mediated cleavage of the template strand BibTex
2006-05-18 R-HSA-164520 Minus strand DNA synthesis resumes BibTex
2006-05-18 R-HSA-164503 First strand transfer mediated by Repeated (R) sequence BibTex
2006-05-18 R-HSA-182859 RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex BibTex
2006-05-18 R-HSA-164519 RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex BibTex
2006-05-18 R-HSA-164504 Synthesis of minus strand strong stop DNA (-sssDNA) BibTex
2006-05-18 R-HSA-164527 Annealing of 3'-end of unwound transfer RNA primer with genomic RNA BibTex
2006-05-18 R-HSA-175250 Suicidal integration leading to smaller circles of viral DNA BibTex
2006-05-18 R-HSA-162590 Import of PIC to the Host Nucleus BibTex
2006-05-18 R-HSA-164522 Terminal (3' end) cleavage of viral DNA BibTex
2006-05-18 R-HSA-164845 Suicidal integration leading to inverted circle formation BibTex
2006-05-18 R-HSA-175174 Association of Ku heterodimer with viral DNA ends BibTex
2006-05-18 R-HSA-175258 2-LTR formation due to circularization of viral DNA BibTex
2006-05-18 R-HSA-175177 Association of XRCC4:DNA ligase IV complex with viral DNA ends BibTex
2006-05-18 R-HSA-175108 Target DNA binding BibTex
2006-05-18 R-HSA-164506 Gap repair completes provirus integration BibTex
2006-05-18 R-HSA-164523 Transesterification to connect viral DNA 3' ends to host DNA 5' ends BibTex
2006-05-18 R-HSA-175117 1-LTR circle formation BibTex
2006-04-02 R-HSA-171291 Folding and Oligomerization of ENV glycoprotein BibTex
2006-02-09 R-HSA-171288 Cleavage of the viral Env gp160 precursor polyprotein BibTex
2005-08-12 R-HSA-825631 Glucagon:GCGR mediates GTP-GDP exchange BibTex
2005-05-19 R-HSA-164423 PhosphoChREBP (Thr 666) is exported to cytosol BibTex
2005-05-18 R-HSA-164381 G alpha (s) auto-inactivates by hydrolysing GTP to GDP BibTex
2005-05-18 R-HSA-381707 PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP BibTex
2005-05-14 R-HSA-163769 Activation of PP2A by Xylulose-5-phosphate BibTex
2005-05-12 R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer BibTex
2005-05-12 R-HSA-163691 Phosphorylation of ChREBP at Serine 568 by AMPK BibTex
2005-05-12 R-HSA-163672 Phosphorylation of ChREBP at Thr(666) by PKA BibTex
2005-05-12 R-HSA-163676 Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA BibTex
2005-05-11 R-HSA-163773 Phosphorylation of PF2K-Pase by PKA catalytic subunit BibTex
2005-05-03 R-HSA-163625 Glucagon binds to Glucagon receptor BibTex
2005-04-27 R-HSA-139898 Caspase-8 activates BID by cleavage BibTex
2005-04-27 R-HSA-139917 tBID activates BAX protein BibTex
2005-03-17 R-HSA-156923 Hydrolysis of eEF1A:GTP BibTex
2005-03-11 R-HSA-156913 Regeneration of eEF1A:GTP by eEF1B activity BibTex
2005-03-11 R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site BibTex
2005-03-11 R-HSA-156908 eEF1A:GTP:aminoacyl tRNA ternary complex formation. BibTex
2005-03-11 R-HSA-156909 eEF1A complexes with GTP BibTex
2005-02-08 R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction BibTex
2004-11-08 R-HSA-141367 Myristoylation of tBID by NMT1 BibTex
2004-08-18 R-HSA-139895 tBID activates BAK protein BibTex
2004-08-18 R-HSA-139897 BAD displaces tBID from BCL-2 sequestration BibTex
2004-08-18 R-HSA-140216 Translocation of PMAIP1 (NOXA) to mitochondria BibTex
2004-08-18 R-HSA-139914 Translocation of BBC3 (PUMA) protein to mitochondria BibTex
2004-06-23 R-HSA-112392 Resumption of elongation after recovery from pausing BibTex
2004-06-23 R-HSA-113411 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing BibTex
2004-06-23 R-HSA-113413 TFIIS-mediated recovery of elongation from arrest BibTex
2004-06-23 R-HSA-113414 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest BibTex
2004-06-22 R-HSA-113402 Formation of DSIF:NELF:early elongation complex BibTex
2004-06-22 R-HSA-112385 Addition of nucleotides leads to transcript elongation BibTex
2004-06-16 R-HSA-8961915 CDC45 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961907 E2F1 binds the CDC45 gene promoter BibTex
2004-06-16 R-HSA-8961846 CCNE1 gene transcription is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961840 E2F1 binds the CCNE1 gene promoter BibTex
2004-06-16 R-HSA-8961961 E2F1 binds the CDC25A gene promoter BibTex
2004-06-16 R-HSA-8961678 ORC1 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961671 E2F1 binds the ORC1 gene promoter BibTex
2004-06-16 R-HSA-8961934 CDK1 gene expression is stimulated by E2F1 and repressed by RBL1 and RBL2 BibTex
2004-06-16 R-HSA-8961920 E2F1 binds the CDK1 gene promoter BibTex
2004-06-16 R-HSA-8961665 PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex BibTex
2004-06-16 R-HSA-8961651 E2F1 binds the PCNA gene promoter BibTex
2004-06-16 R-HSA-8962050 TYMS gene expression BibTex
2004-06-16 R-HSA-8961863 E2F1 binds the DHFR gene promoter BibTex
2004-06-16 R-HSA-8961991 E2F1 binds the TK1 gene promoter BibTex
2004-06-16 R-NUL-8963657 E2F1 binds the Tk1 gene promoter BibTex
2004-06-16 R-HSA-8961688 E2F1 binds the FBXO5 gene promoter BibTex
2004-06-16 R-HSA-8961946 E2F1 binds the CDT1 gene promoter BibTex
2004-06-16 R-HSA-8961874 DHFR gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961619 CDC6 gene expression is stimulated by E2F1 and repressed by the DREAM complex BibTex
2004-06-16 R-HSA-8961620 E2F1 binds the CDC6 gene promoter BibTex
2004-06-16 R-HSA-8961632 POLA1 gene transcription is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961636 E2F1 binds the POLA1 gene promoter BibTex
2004-06-16 R-HSA-8961888 E2F1 binds the CCNA1 gene promoter BibTex
2004-06-16 R-HSA-8961952 CDT1 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961699 FBXO5 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961895 CCNA1 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-8961982 RRM2 gene expression is stimulated by E2F1 and inhibited by E2F6 BibTex
2004-06-16 R-HSA-8961972 E2F1 binds the RRM2 gene promoter BibTex
2004-06-16 R-MMU-8963630 E2f1 binds the Rrm2 gene promoter BibTex
2004-06-16 R-HSA-8962039 TK1 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-NUL-9616935 Tk1 gene expression is stimulated by E2F1 BibTex
2004-06-16 R-HSA-113638 Association of Cyclin B/Cdk1 with replicative origin inhibits pre-RC formation BibTex
2004-05-26 R-HSA-113643 Replication initiation regulation by Rb1/E2F1 BibTex
2004-05-06 R-HSA-112381 Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex BibTex
2004-05-03 R-HSA-113407 DSIF complex binds to RNA Pol II (hypophosphorylated) BibTex
2004-04-28 R-HSA-112383 Hypophosphorylation of RNA Pol II CTD by FCP1P protein BibTex
2004-04-28 R-HSA-113409 Abortive termination of early transcription elongation by DSIF:NELF BibTex
2004-02-02 R-HSA-6781824 Active RNA Pol II complex transcribes lesion-containing DNA template BibTex
2004-02-02 R-HSA-6781818 RNA Pol II initiates transcription from damaged DNA template BibTex
2004-02-02 R-HSA-5690991 Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER BibTex
2004-02-02 R-HSA-5691006 XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site BibTex
2004-02-02 R-HSA-5690997 Ligation of newly synthesized repair patch to incised DNA in GG-NER BibTex
2004-02-02 R-HSA-5691001 Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER BibTex
2004-01-29 R-HSA-6782004 Assembly of the pre-incision complex in TC-NER BibTex
2004-01-29 R-HSA-6781833 ERCC8 (CSA) binds stalled RNA Pol II BibTex
2004-01-29 R-HSA-6781840 ERCC6 binds stalled RNA Pol II BibTex
2004-01-29 R-HSA-5691004 XPC binds RAD23 and CETN2 BibTex
2004-01-29 R-HSA-110319 Elongation by POLH BibTex
2004-01-29 R-HSA-110317 Insertion of correct bases opposite the lesion by POLH BibTex
2004-01-29 R-HSA-110316 POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template BibTex
2004-01-29 R-HSA-110308 REV1 inserts dCMP opposite to AP sites in DNA BibTex
2004-01-29 R-HSA-110307 REV1 binds AP-dsDNA BibTex
2004-01-29 R-HSA-110311 POLZ extends translesion synthesis BibTex
2004-01-22 R-HSA-109955 Formation of ERCC1:XPF heterodimeric complex BibTex
2003-12-05 R-HSA-83677 C4 deamination of cytidine BibTex
2003-12-05 R-HSA-77609 Binding of APOBEC-1 to form editosome BibTex
2003-12-05 R-HSA-77608 Binding of A1CF to stem-looped RNA BibTex
2003-12-05 R-HSA-77607 Formation of stem-loop structure in ApoB mRNA BibTex
2003-12-05 R-HSA-77612 Formation of dsRNA structure by looping BibTex
2003-10-03 R-HSA-200555 acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate BibTex
2003-10-03 R-HSA-75848 ACLY tetramer transforms CIT to Ac-CoA BibTex
2003-10-02 R-HSA-75886 glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] BibTex
2003-10-02 R-HSA-75887 Conversion of Glycerol to Glycerol-3-phosphate BibTex
2003-10-02 R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L BibTex
2003-10-02 R-HSA-549112 G3P is acylated to 1-acyl LPA by AGPAT6 BibTex
2003-10-02 R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol BibTex
2003-10-02 R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate BibTex
2003-07-16 R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA BibTex