Carl-Henrik Heldin

Affiliation
Ludwig Institute for Cancer Research, Uppsala Branch
Authored Pathways (1/1)
Date Identifier Pathway Reference
2006-02-02 R-HSA-170834 Signaling by TGF-beta Receptor Complex BibTex
Authored Reactions (15/22)
Date Identifier Reaction Reference
2006-02-02 R-HSA-178218 SMAD7:SMURF complex binds to phosphorylated TGFBR1 BibTex
2006-02-02 R-HSA-178215 SMAD7:SMURF1 complex is exported to the cytosol BibTex
2006-02-02 R-HSA-173542 SMURF2 ubiquitinates SMAD2 BibTex
2006-02-02 R-HSA-178208 SMAD7 binds to SMURF2 BibTex
2006-02-02 R-HSA-2167917 SMAD7 binds to SMURF1 BibTex
2006-02-02 R-HSA-173512 I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) BibTex
2006-02-02 R-NUL-2167890 Smad7 recruits GADD34:PP1CC to phosphorylated TGF-beta receptor complex BibTex
2006-02-02 R-HSA-178189 SMAD7 recruits GADD34:PP1 to phosphorylated TGFBR BibTex
2006-02-02 R-NUL-2167872 PP1CC dephosphorylates TGFBR1 BibTex
2006-02-02 R-HSA-178178 PP1 dephosphorylates TGFBR1 BibTex
2006-02-02 R-HSA-173545 Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling BibTex
2006-02-02 R-HSA-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling BibTex
2006-02-02 R-HSA-170844 Latent TGF-beta-1 is cleaved by furin BibTex
2006-02-02 R-HSA-177107 Secretion and activation of the latent large complex of TGF-beta-1 BibTex
2006-02-02 R-HSA-170861 Dimeric TGF-beta-1 binds to the receptor BibTex
Reviewed Pathways (10/10)
Date Identifier Pathway Reference
2008-11-24 R-HSA-186763 Downstream signal transduction BibTex
2008-11-24 R-HSA-186797 Signaling by PDGF BibTex
2008-02-28 R-HSA-177929 Signaling by EGFR BibTex
2008-02-12 R-HSA-180336 SHC1 events in EGFR signaling BibTex
2008-02-12 R-HSA-179812 GRB2 events in EGFR signaling BibTex
2008-02-12 R-HSA-180292 GAB1 signalosome BibTex
2008-02-12 R-HSA-182971 EGFR downregulation BibTex
2008-02-12 R-HSA-212718 EGFR interacts with phospholipase C-gamma BibTex
2007-11-12 R-HSA-201451 Signaling by BMP BibTex
2006-04-18 R-HSA-170834 Signaling by TGF-beta Receptor Complex BibTex
Reviewed Reactions (15/96)
Date Identifier Reaction Reference
2008-11-24 R-HSA-382058 Nck binds to the active PDGF receptor BibTex
2008-11-24 R-HSA-380780 Activation of Src BibTex
2008-11-24 R-HSA-186798 GAP binds to PDGF-beta receptors only BibTex
2008-11-24 R-HSA-382055 Grb7 binds to the active PDGF receptor BibTex
2008-11-24 R-HSA-380782 STAT binds to the active receptor BibTex
2008-11-24 R-HSA-186778 SHP2 binds to the active receptor BibTex
2008-11-24 R-HSA-186800 PI3K catalyses the phosphorylation of PIP2 to PIP3 BibTex
2008-11-24 R-HSA-186819 SH2 domain of Src binds to the active receptor BibTex
2008-11-24 R-HSA-1524182 Activated PLC gamma dissociates from the PDGF receptor BibTex
2008-11-24 R-HSA-382052 p130Cas and C3G bind PDGFR bound Crk BibTex
2008-11-24 R-HSA-382056 Crk binds to the active PDGF receptor BibTex
2008-11-24 R-HSA-1524186 Phosphorylation of PLCgamma by PDGFR BibTex
2008-11-24 R-HSA-186765 PLC-gamma binds to the active receptor BibTex
2008-11-24 R-HSA-186834 Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos) BibTex
2008-11-24 R-HSA-382054 PDGF binds to extracellular matrix proteins BibTex