Evripidis Gavathiotis

 ORCID
https://orcid.org/0000-0001-6319-8331
Reviewed Pathways (9/9)
Date Identifier Pathway Reference
2020-05-04 R-HSA-9648002 RAS processing BibTex
2020-05-04 R-HSA-6802957 Oncogenic MAPK signaling BibTex
2020-05-04 R-HSA-9753512 Signaling by RAS GTPase mutants BibTex
2020-05-04 R-HSA-9652817 Signaling by MAPK mutants BibTex
2020-05-04 R-HSA-9652169 Signaling by MAP2K mutants BibTex
2020-05-04 R-HSA-9660537 Signaling by MRAS-complex mutants BibTex
2020-05-04 R-HSA-9726840 SHOC2 M1731 mutant abolishes MRAS complex function BibTex
2020-05-04 R-HSA-9726842 Gain-of-function MRAS complexes activate RAF signaling BibTex
2020-05-04 R-HSA-9656223 Signaling by RAF1 mutants BibTex
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Reviewed Reactions (15/48)
Date Identifier Reaction Reference
2020-05-04 R-HSA-9658253 RAS:GTP binds PI3K BibTex
2020-05-04 R-HSA-9647978 pro-RAS proteins are farnesylated BibTex
2020-05-04 R-HSA-9647999 RCE1 cleaves S-Farn proRAS proteins BibTex
2020-05-04 R-HSA-9647977 ICMT methylates S-Farn RAS proteins BibTex
2020-05-04 R-HSA-9649732 Mature S-Farn-Me KRAS4B translocates to plasma membrane BibTex
2020-05-04 R-HSA-9647982 S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated BibTex
2020-05-04 R-HSA-9647980 mature RAS proteins translocate to plasma membrane BibTex
2020-05-04 R-HSA-9649733 mature p21 RAS binds GDP BibTex
2020-05-04 R-HSA-9649736 RAS intrinsic GTPase activity hydrolyzes GTP to GDP BibTex
2020-05-04 R-HSA-9649735 Intrinsic nucleotide exchange on RAS BibTex
2020-05-04 R-HSA-9657599 Dual mechanism MAP2K inhibitors bind MAP2Ks BibTex
2020-05-04 R-HSA-9657603 Dual mechanism MAPK inhibitors bind MAPKs BibTex
2020-05-04 R-HSA-9657608 Single mechanism MAPK inhibitors bind phosphorylated MAPK BibTex
2020-05-04 R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks BibTex
2020-05-04 R-HSA-9653503 KRAS4B is phosphorylated on serine 181 BibTex
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