Chyuan-Chuan Wu

 ORCID
https://orcid.org/0000-0002-7389-8777
Reviewed Pathways (1/1)
Date Identifier Pathway Reference
2024-10-27 R-HSA-9913635 Strand-asynchronous mitochondrial DNA replication BibTex
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Reviewed Reactions (15/15)
Date Identifier Reaction Reference
2024-10-27 R-HSA-9914903 LIG3 (Ligase III) ligates nascent mitochondrial DNA strands BibTex
2024-10-27 R-HSA-9914870 MGME1 cleaves 5' DNA flap from nascent mitochondrial DNA BibTex
2024-10-27 R-HSA-9914858 RNASEH1 cleaves RNA primer from nascent H strand, leaving RNA dinucleotides BibTex
2024-10-27 R-HSA-9914498 POLG in the replisome polymerizes the L strand BibTex
2024-10-27 R-HSA-9914409 POLRMT polymerizes RNA primer for mitochondrial L strand replication BibTex
2024-10-27 R-HSA-9914404 POLRMT and POLG bind the mitochondrial L strand replication origin (OriL) BibTex
2024-10-27 R-HSA-9914478 SSBP1 binds the displaced parental H strand BibTex
2024-10-27 R-HSA-9914364 POLG in the replisome polymerizes the H strand BibTex
2024-10-27 R-HSA-9914438 TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork BibTex
2024-10-27 R-HSA-9913634 POLG:POLG2 and TWNK (PEO1) bind mitochondrial DNA:RNA primer to form H strand replisome BibTex
2024-10-27 R-HSA-9913637 RNASEH1 cleaves R-loop RNA to yield RNA primer for H strand polymerization BibTex
2024-10-27 R-HSA-9915448 POLRMT polymerizes R-loop RNA BibTex
2024-10-27 R-HSA-9915449 RNASEH1 cleaves RNA primer from nascent L strand, leaving RNA dinucleotides BibTex
2024-10-27 R-HSA-9915442 EXOG cleaves RNA dinucleotide from nascent mitochondrial DNA BibTex
2024-10-27 R-HSA-9914922 TOP3A (Topoisomerase 3a) decatenates mitochondrial DNA BibTex
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