Pierce W Ford

 ORCID
https://orcid.org/0000-0002-6492-593X
Reviewed Pathways (4/4)
Date Identifier Pathway Reference
2025-08-09 R-HSA-9948299 Ribosome-associated quality control BibTex
2025-08-09 R-HSA-9954709 Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide BibTex
2025-08-09 R-HSA-9954716 ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA BibTex
2025-08-09 R-HSA-9954714 PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA BibTex
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Reviewed Reactions (15/23)
Date Identifier Reaction Reference
2025-08-11 R-HSA-9948301 ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit BibTex
2025-08-09 R-HSA-9954737 RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide BibTex
2025-08-09 R-HSA-9954727 RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 BibTex
2025-08-09 R-HSA-9948458 NEMF polymerizes alanine residues onto the C-terminus of the nascent peptide ("CAT tailing") BibTex
2025-08-09 R-HSA-9948318 LTN1 and TCF25 bind NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala BibTex
2025-08-09 R-HSA-9948300 RQT complex:K63polyUb-80S ribosome dissociates yielding K63polyUb-40S subunit and 60S subunit:peptidyl-tRNA with nascent peptide BibTex
2025-08-09 R-HSA-9948291 RQT complex binds K63polyUb-80S ribosome:no-go mRNA:peptidyl-tRNA with nascent peptide BibTex
2025-08-09 R-HSA-9948317 ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome BibTex
2025-08-09 R-HSA-9948415 VCP hexamer and NPLOC4:UFD1 bind K48polyubiquitin of LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide BibTex
2025-08-09 R-HSA-9948362 LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide BibTex
2025-08-09 R-SCE-9950045 CDC48 hexamer, UFD1, and NPL4 bind K48polyubiquitin of RKR1:RQC2:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide BibTex
2025-08-09 R-HSA-9954723 NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 binds alanine-tailed nascent peptide BibTex
2025-08-09 R-HSA-9954721 NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 K48 polyubiquitinates alanine-tailed nascent peptide BibTex
2025-08-09 R-HSA-9949632 VCP hexamer extracts K48 polyubiquitinated alanine-tailed nascent peptide from VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide BibTex
2025-08-09 R-HSA-9948427 ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide BibTex
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