Search results for Q9BVC4

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Protein (2 results from a total of 2)

Identifier: R-HSA-165676
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: MLST8: Q9BVC4
Identifier: R-HSA-5083646
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: MLST8: Q9BVC4

Icon (1 results from a total of 1)

Species: Homo sapiens
Curator: Bruce May
Designer: Cristoffer Sevilla
mTORC1 icon
mTORC1, also known as mammalian target of rapamycin complex 1 or mechanistic target of rapamycin complex 1, is a protein complex that functions as a nutrient/energy/redox sensor and controls protein synthesis. mTOR Complex 1 (mTORC1) is composed of mTOR itself, regulatory-associated protein of mTOR (Raptor), mammalian lethal with SEC13 protein 8 (MLST8), PRAS40 and DEPTOR. This complex embodies the classic functions of mTOR, namely as a nutrient/energy/redox sensor and controller of protein synthesis. The activity of this complex is regulated by rapamycin, insulin, growth factors, phosphatidic acid, certain amino acids and their derivatives (e.g., l-leucine and β-hydroxy β-methylbutyric acid), mechanical stimuli, and oxidative stress
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