Search results for ACAT2

Showing 4 results out of 4

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Types

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Species

Types

Compartments

Reaction types

Search properties

Protein (2 results from a total of 2)

Identifier: R-HSA-8848218
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: ACAT2: Q9BWD1
Identifier: R-HSA-8876492
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: SOAT2: O75908

Complex (1 results from a total of 1)

Identifier: R-HSA-8848217
Species: Homo sapiens
Compartment: cytosol

Reaction (1 results from a total of 1)

Identifier: R-HSA-8848215
Species: Homo sapiens
Compartment: cytosol
Three human enzymes can utilise ketone bodies for energy production. Two mitochondrial enzymes function in ketolysis whereas a cytosolic enzyme is implicated in cytosolic cholesterol biosynthesis. Cytosolic acetyl-CoA acetyltransferase tetramer (ACAT2 tetramer) (Song et al. 1994) catalyses the condensation of two acetyl-CoA (Ac-CoA) molecules to form acetoacetyl-CoA (ACA-CoA). This is the first step in the biosynthesis of cholesterol (Fukao et al. 1997).
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