Search results for AGMAT

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Species

Types

Compartments

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-350595
Species: Homo sapiens
Compartment: mitochondrion
Primary external reference: UniProt: AGMAT: Q9BSE5

Pathway (1 results from a total of 1)

Identifier: R-HSA-351143
Species: Homo sapiens
Compartment: cytosol
Agmatine is an amine that is formed by decarboxylation of L-arginine by the enzyme arginine decarboxylase (ADC) and hydrolyzed by the enzyme agmatinase to putrescine. Agmatine binds to several target receptors in the brain and has been proposed as a novel neuromodulator (Reghunathan 2006). Agmatine has the potential to serve in the coordination of the early and repair phase pathways of arginine in inflammation (Satriano, 2003).

Reaction (2 results from a total of 2)

Identifier: R-HSA-350598
Species: Homo sapiens
Compartment: cytosol
Agmatine is polyamine formed by decarboxylation of L-arginine by arginine decarboxylase (ADC). Human ADC is a 460-amino acid protein that shows about 48% identity to mammalian ornithine decarboxylase (ODC) but has no ODC activity.
Identifier: R-HSA-350604
Species: Homo sapiens
Compartment: cytosol
As it hydrolyzes a guanidino group within agmatine and also contains signature amino acid residues that act as ligand binding sites for the potential Mn(++) cofactor, agmatinase is classified as a member of the arginase superfamily (Morris, 2003).
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