Search results for ALDH1A1

Showing 6 results out of 6

×

Species

Types

Compartments

Reaction types

Search properties

Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

ALDH1A1

Identifier: R-HSA-71688
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: ALDH1A1: P00352

Complex (1 results from a total of 1)

ALDH1A1 tetramer

Identifier: R-HSA-71689
Species: Homo sapiens
Compartment: cytosol

Reaction (3 results from a total of 3)

ALDH1A1 oxidises GA to DGA

Identifier: R-HSA-6813749
Species: Homo sapiens
Compartment: cytosol
Retinal dehydrogenase 1 (ALDH1A1 tetramer) is a cytosolic aldehyde dehydrogenase that can oxidise glyceraldehyde (GA) to D-glycerate (DGA) (Yoval-Sanchez et al. 2013). DGA is a metabolite in a minor pathway of fructose catabolism and serine catabolism.

acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]

Identifier: R-HSA-71691
Species: Homo sapiens
Compartment: cytosol
ALDH1A1 (aldehyde dehydrogenase) in the cytosol catalyzes the reaction of acetaldehyde and NAD+ to form acetate and NADH + H+ (Inoue et al. 1979). The active form of the enzyme is a tetramer (Ni et al. 1999).

ALDHs oxidise atRAL to atRA

Identifier: R-HSA-5362522
Species: Homo sapiens
Compartment: cytosol
Several aldehyde dehydrogenases catalyse the irreversible oxidation of retinal to retinoic acid. ALDH1A1, 2 and 3 utilise NAD+ as cofactor to oxidise all-trans-retinal (atRAL) to all-trans-retinoic acid (atRA). They are cytosolic enzymes which are functional in their homotetrameric states (Yoshida et al. 1993, Duester 2008, Bchini et al. 2013).

Set (1 results from a total of 1)

ALDH1A1,2,3 tetramers

Identifier: R-HSA-5362725
Species: Homo sapiens
Compartment: cytosol
Cite Us!