Search results for ALDH1L1

Showing 3 results out of 3

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-6808507
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: ALDH1L1: O75891

Complex (1 results from a total of 1)

Identifier: R-HSA-6808495
Species: Homo sapiens
Compartment: cytosol

Reaction (1 results from a total of 1)

Identifier: R-HSA-6808496
Species: Homo sapiens
Compartment: cytosol
ALDH1L1 (cytosolic 10-formyltetrahydrofolate dehydrogenase) catalyzes the NADP-dependent dehydrogenation of 10-formyl-THFPG (10-formyltetrahydrofolate polyglutamate) to THFPG (tetrahydrofolate polyglutamate). This reaction has the effect of depleting the pool of folate charged with 1-carbon groups and might thus serve to regulate the size of the pool and the overall pace of cytosolic biosynthetic reactions dependent on it (Krupenko et al. 2010; Strickland et al. 2011).
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