Search results for C6
Showing 2 results out of 2
Icon (2 results from a total of 2)
Species:
Homo sapiens
Curator:
Thawfeek Varusai
Designer:
Cristoffer Sevilla
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells
Species:
Homo sapiens
Curator:
Thawfeek Varusai
Designer:
Cristoffer Sevilla
The membrane attack complex (MAC) or terminal complement complex (TCC) is a structure typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is one of the effector proteins of the immune system. MAC forms transmembrane channels that disrupt the cell membrane of target cells, leading to cell lysis and death. Active MAC is composed of the subunits C5b, C6, C7, C8 and several C9 molecules
© 2024 Reactome
