Search results for CYP2C9

Showing 5 results out of 5

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

CYP2C9

Identifier: R-HSA-211017
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: CYP2C9: P11712

Reaction (3 results from a total of 3)

CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation

Identifier: R-HSA-211988
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane, endoplasmic reticulum lumen
Tolbutamide is an oral hypoglycemic agent whose action is terminated by hydroxylation of the tolylsulfonyl methyl moiety. The reaction is catalyzed by CYP2C9.

Arachidonic acid is hydroxylated to 19-HETE by CYP(2)

Identifier: R-HSA-2161814
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane, endoplasmic reticulum lumen
Several cytochrome P450s (CYPs) convert arachidonic acid to 19-hydroxyeicosatetraenoic acid (19-HETE). The CYPs and their references are as follows: CYP2C8 (Bylund et al. 1998); CYP2C9 (Bylund et al. 1998); CYP2C19 (Bylund et al. 1998); CYP4A11 (Gainer et al. 2005); CYP2U1 (Chuang et al. 2004); CYP1A1, CYP1A2, CYP1B1 (Choudhary et al. 2004).

Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)

Identifier: R-HSA-2161899
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane, cytosol
Several cytochrome P450s (CYPs) convert arachidonic acid to 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids (8,9-, 11,12-, 14,15-EETs). The CYPs and their references are as follows: CYP1A1, CYP1A2, CYP1B1 (Choudhary et al. 2004); CYP2C8, CYP2C9 (Rifkind et al. 1995); CYP2C19 (Bylund et al. 1998, Rifkind et al. 1995); CYP2J2 (Wu et al. 1996).

Set (1 results from a total of 1)

Cytochrome P450 (CYP2C9 based)

Identifier: R-HSA-3219414
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
This CandidateSet contains sequences identified by William Pearson's analysis of Reactome catalyst entities. Catalyst entity sequences were used to identify analagous sequences that shared overall homology and active site homology. Sequences in this Candidate set were identified in an April 24, 2012 analysis. Further candidates were identified by Ralf Stephan in a July 15, 2023 analysis.
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