Search results for CYP4B1

Showing 3 results out of 3

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Species

Types

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-211013
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: CYP4B1: P13584

Reaction (1 results from a total of 1)

Identifier: R-HSA-211924
Species: Homo sapiens
Compartment: smooth endoplasmic reticulum
Injury to the eye's surface provokes an inflammatory response, mediated, in part, by 12-hydroxyeicosanoids. CYP4B1 catalyses the 12-hydroxylation of arachidonic acid (ARA) to 12-HETE and 12-HETrE (12-hydroxy-5,8,10,14-eicosatetraenoic acid and 12-hydroxy-5,8,14-eicosatrienoic acid respectively). Both these metabolites possess potent inflammatory and angiogenic properties (Ashkar et al. 2004). The example of 12-HETE formation only is shown here.

Set (1 results from a total of 1)

Identifier: R-HSA-3219417
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
This CandidateSet contains sequences identified by William Pearson's analysis of Reactome catalyst entities. Catalyst entity sequences were used to identify analagous sequences that shared overall homology and active site homology. Sequences in this Candidate set were identified in an April 24, 2012 analysis.
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