Search results for DCXR

Showing 5 results out of 5

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Species

Types

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Species

Types

Compartments

Reaction types

Search properties

Protein (2 results from a total of 2)

Identifier: R-HSA-5660054
Species: Homo sapiens
Compartment: plasma membrane
Primary external reference: UniProt: DCXR: Q7Z4W1
Identifier: R-HSA-5662854
Species: Homo sapiens
Compartment: plasma membrane
Primary external reference: UniProt: DCXR: Q7Z4W1

Complex (1 results from a total of 1)

Identifier: R-HSA-5660027
Species: Homo sapiens
Compartment: plasma membrane

Reaction (2 results from a total of 2)

Identifier: R-HSA-5661240
Species: Homo sapiens
Compartment: cytosol, plasma membrane
L-xylulose reductase (DCXR, also known as dicarbonyl/L-xylulose reductase) catalyzes the reversible NADPH dependent reduction of cytosolic L-xylulose to xylitol (Nakagawa et al. 2002). The enzyme is a tetramer (El Kabbani et al.2004) and may be associated with the plasma membrane (Boue et al. 1996). Mutations that inactivate DCXR are associated with essential pentosuria (Pierce et al. 2011; Wang & van Eys 1970).
Identifier: R-HSA-5662851
Species: Homo sapiens
Compartment: cytosol, plasma membrane
Mutations that inactivate DCXR block the conversion of L-xylulose to xylitol. The two mutant alleles that have been characterized by DNA sequencing would encode truncated mRNAs and encode no detectable protein product. One of these mutant alleles, DCXR c.583?C, is annotated here (Pierce et al. 2011; Wang & van Eys 1970).
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