Search results for DHCR7

Showing 7 results out of 7

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-196423
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: DHCR7: Q9UBM7

DNA Sequence (1 results from a total of 1)

Identifier: R-HSA-2393971
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: ENSEMBL: ENSEMBL:ENSG00000172893

Reaction (4 results from a total of 4)

Identifier: R-HSA-2426155
Species: Homo sapiens
Compartment: nucleoplasm
SREBP1A (SREBF1A) and SREBP2, together with NF-Y and SP1, bind and transactivate the promoter of the DHCR7 gene (Reed et al. 2008).
Identifier: R-HSA-6807055
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane, cytosol
DHCR7 (7-dehydrocholesterol reductase) associated with the endoplasmic reticulum membrane reduces 7-dehydroCHOL (7-dehydrocholesterol) to CHOL (cholesterol) (Kandutsch & Russell1960; Mitsche et al. 2015; Moebius et al. 1998).
Identifier: R-HSA-1655827
Species: Homo sapiens
Compartment: nucleoplasm, endoplasmic reticulum membrane
SREBF1A (SREBP1A) and SREBF2 (SREBP2) bind the promoter of the 7-Dehydrocholesterol Reductase (DHCR) gene and enhance transcription (Sakakura et al. 2001, Reed et al. 2008, reviewed in Horton et al. 2002).
The DHCR7 gene is transcribed to yield mRNA and the mRNA is translated to yield protein.
Identifier: R-HSA-196402
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
Cholesta-5,7,24-trien-3beta-ol and NADPH + H+ react to form desmosterol and NADP+. This reaction is catalyzed by DHCR7, associated with the endoplasmic reticulum membrane. The biochemical details of the reaction are inferred from those of the reaction catalyzed by the well-studied rat enzyme (Bae et al. 1999).

Complex (1 results from a total of 1)

Identifier: R-HSA-2426124
Species: Homo sapiens
Compartment: nucleoplasm
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