Search results for DHRS3

Showing 5 results out of 5

×

Species

Types

Compartments

Search properties

Species

Types

Compartments

Search properties

Protein (2 results from a total of 2)

Identifier: R-HSA-2980986
Species: Homo sapiens
Compartment: photoreceptor outer segment membrane
Primary external reference: UniProt: DHRS3: O75911
Identifier: R-HSA-5419172
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane
Primary external reference: UniProt: DHRS3: O75911

Set (1 results from a total of 1)

Identifier: R-HSA-5419219
Species: Homo sapiens
Compartment: endoplasmic reticulum membrane

Reaction (2 results from a total of 2)

Identifier: R-HSA-5419165
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
Multiple reductases may contribute to the reduction of all-trans-retinal (atRAL) to all-trans-retinol (atROL), including RDH11 (aka PSDR1, RalR1), RDH14, DHRS3 (aka retSDR1, RDH17) and DHRS4 (aka RRD, SCAD-SRL) (Haeseleer et al. 1998, Haeseleer et al. 2002, Kedishvili et al. 2002, Lin et al. 2001, Zhen et al. 2003, Belyaeva et al. 2008).
Identifier: R-HSA-5362721
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
11-cis-retinol dehydrogenase (RDH5) and RDH11 catalyse the final step in the biosynthesis of 11-cis-retinal (11cRAL), the universal chromophore of visual pigments, whereas RDH8, RDH12, and DHRS3 (retSDR1) catalyze the conversion of all-trans-retinal (atRAL) into all-trans-retinol (atROL) to maintain the cycle (Parker & Crouch 2010). Defects in the RDH5 gene can cause fundus albipunctatus (RPA; MIM:136880), a rare form of stationary night blindness characterised by a delay in the regeneration of cone and rod photopigments (Yamamoto et al. 1999).
Cite Us!