JMJD7 (JmjC domain-containing protein 7) catalyzes the 3-hydroxlation of a lysine residue of DRG1 (developmentally-regulated GTP-binding protein 1). The catalytically active form of JMJD7 is a dimer, each monomeric subunit of which is associated with a Fe2+ ion (Markolovic et al. 2018). DRG1 occurs as a heterdimer with one molecule of ZC3H15 (DFRP1) (Ishikawa et al. 2005, 2009).
JMJD7 (JmjC domain-containing protein 7) catalyzes the 3-hydroxlation of a lysine residue of DRG2 (developmentally-regulated GTP-binding protein 2). The catalytically active form of JMJD7 is a dimer, each monomeric subunit of which is associated with a Fe2+ ion (Markolovic et al. 2018). DRG2 occurs as a heterdimer with one molecule of RWDD1 (DFRP2 IIshikawa et al. 2005, 2009).