Based on studies in mice, transcription of the GAMT gene, encoding guanidinoacetate N-methyltransferase, is directly stimulated by MECP2 (Chahrour et al. 2008).
Based on studies in mice, MECP2 binds the promoter region of the GAMT gene, encoding guanidinoacetate N-methyltransferase, which plays an important role during nervous system development (Chahrour et al. 2008).