Search results for GTF2B

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Protein (1 results from a total of 1)

Identifier: R-HSA-65888
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: GTF2B: Q00403

Reaction (1 results from a total of 1)

Identifier: R-HSA-6810234
Species: Homo sapiens
Compartment: nucleoplasm
The promoter of an snRNA gene binds the basal transcription factors TFIIA, TFIIB (GTF2B), TFIIE, and TFIIF (Bernues et al. 1993, Kuhlman et al. 1999). Rather than the TFIID complex found at promoters of mRNA-encoding genes, a unique complex containing TBP (Sadowski et al. 1993) and snTAFc is present at promoters of snRNA genes (Zaborowska et al. 2012). The P-TEFb complex is also observed at snRNA genes, however, it seems to play a role more in 3' processing than in elongation (Medlin et al. 2005). CDK7 is also present and phosphorylates the C-terminal domain of RNA polymerase II (Glover-Cutter et al. 2009).
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