Search results for ITPA
Showing 5 results out of 5
Protein (1 results from a total of 1)
Identifier: R-HSA-2509850
Species:
Homo sapiens
Compartment:
cytosol
Primary external reference: UniProt: ITPA:
Q9BY32
Complex (1 results from a total of 1)
Identifier: R-HSA-2509833
Species:
Homo sapiens
Compartment:
cytosol
Reaction (3 results from a total of 3)
Identifier: R-HSA-2509831
Species:
Homo sapiens
Compartment:
cytosol
Cytosolic ITPA dimer catalyzes the reaction of XTP and water to form XMP and PPi (pyrophosphate). Mg++ is required for enzymatic activity. The hydrolysis of XTP is thought to prevent its incorporation into mRNA, which would lead to aberrant protein synthesis (Lin et al. 2001; Abolhassani et al. 2010).
Identifier: R-HSA-2509838
Species:
Homo sapiens
Compartment:
cytosol
Cytosolic ITPA dimer catalyzes the reaction of dITP and water to form dIMP and PPi (pyrophosphate). Mg++ is required for enzymatic activity. The hydrolysis of dITP is thought to prevent its incorporation into DNA, which would be mutagenic (Lin et al. 2001; Abolhassani et al. 2010).
Identifier: R-HSA-2509827
Species:
Homo sapiens
Compartment:
cytosol
Cytosolic ITPA dimer catalyzes the reaction of ITP and water to form IMP and PPi (pyrophosphate). Mg++ is required for enzymatic activity. The hydrolysis of ITP is thought to prevent its incorporation into mRNA, which would lead to aberrant protein synthesis (Lin et al. 2001; Abolhassani et al. 2010).
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