Search results for MTAP

Showing 7 results out of 7

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Species

Types

Compartments

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-1237091
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: MTAP: Q13126

DNA Sequence (1 results from a total of 1)

Identifier: R-HSA-8950683
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: ENSEMBL: MTAP: ENSG00000099810

Complex (1 results from a total of 1)

Identifier: R-HSA-1237147
Species: Homo sapiens
Compartment: cytosol

Interactor (1 results from a total of 1)

Identifier: P11137
Species: Homo sapiens
Primary external reference: UniProt: P11137

Reaction (2 results from a total of 2)

Identifier: R-HSA-8950365
Species: Homo sapiens
Compartment: cytosol, nucleoplasm
Experiments using human cord blood CD4(+) T cells show 22 protein spots and 20 protein spots, upregulated and downregulated proteins respectively, following Interleukin-12 stimulation (Rosengren et.al, 2005). Among the up-regulated proteins is :S-methyl-5'-thioadenosine phosphorylase(MTAP).
Identifier: R-HSA-1237160
Species: Homo sapiens
Compartment: cytosol
MTA phosphorylase catalyzes the cleavage of adenine from S-methylthioadenosine (MTA) and subsequent phosphorylation of the product, yielding 5'-methylthio ribose-1-phosphate (Kamatani et al. 1981). The active form of the enzyme is a homotrimer (Della Ragione et al. 1985). Mutations in the gene are associated with a rare bone dysplasia and cancer syndrome, DMS-MFH (Camacho-Vanegas et al. 2012).

Pathway (1 results from a total of 1)

Identifier: R-HSA-8950505
Species: Homo sapiens
Compartment: nucleoplasm
Experiments using human cord blood CD4(+) T cells show 22 protein spots and 20 protein spots, upregulated and downregulated proteins respectively, following Interleukin-12 stimulation (Rosengren et.al, 2005). The identified upregulated proteins are: BOLA2, PSME2, MTAP, CA1, GSTA2, RALA, CNN2, CFL1, TCP1, HNRNPDL, MIF, AIP, SOD1, PPIA and PDCD4.
And the identified downregulated proteins are:
ANXA2, RPLP0, CAPZA1, SOD2, SNRPA1, LMNB1, LCP1, HSPA9, SERPINB2, HNRNPF, TALDO1, PAK2, TCP1, HNRNPA2B1, MSN, PITPNA, ARF1, SOD2, ANXA2, CDC42, RAP1B and GSTO1.
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