Search results for NAMPT
Showing 5 results out of 5
Reaction (5 results from a total of 5)
Identifier: R-HSA-5663122
Species:
Homo sapiens
Compartment:
nucleoplasm
As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) heterodimer binds an E-box element in the promoter of the NAMPT gene and enhances transcription.
Identifier: R-HSA-1368889
Species:
Homo sapiens
Compartment:
nucleoplasm,
cytosol
The NAMPT (NamPRT) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) heterodimer enhances transcription of NAMPT.
As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) heterodimer binds an E-box element in the promoter of the NAMPT gene and enhances transcription.
As inferred from mouse, the BMAL1:CLOCK (ARNTL:CLOCK) heterodimer binds an E-box element in the promoter of the NAMPT gene and enhances transcription.
Identifier: R-HSA-9769316
Species:
Homo sapiens
Compartment:
nucleoplasm
Based on studies in sheep (West et al. 2013) and rat (Brigidi et al. 2019) neurons, NPAS4 transcription factor, in cooperation with its heterodimerization partners ARNT, ARNT2, and ARNTL, binds the promoter of the circadian rhythm-controlled gene NAMPT, encoding Nicotinamide phosphoribosyltransferase.
Identifier: R-HSA-9769323
Species:
Homo sapiens
Compartment:
nucleoplasm,
cytosol
Based on studies in sheep (West et al. 2013) and rat (Brigidi et al. 2019) neurons, NPAS4 transcription factor, in cooperation with its heterodimerization partners ARNT, ARNT2, and ARNTL, directly stimulates transcription of the circadian rythm-controlled gene NAMPT, encoding Nicotinamide phosphoribosyltransferase.
The rhythmic production of NAD+ may function to fine-tune the daily cycles of energy storage and utilization and to coordinate these processes with the rest-activity cycle (Ramsay et al. 2009).
The rhythmic production of NAD+ may function to fine-tune the daily cycles of energy storage and utilization and to coordinate these processes with the rest-activity cycle (Ramsay et al. 2009).
Identifier: R-HSA-197250
Species:
Homo sapiens
Compartment:
cytosol
Nicotinamide phosphoribosyltransferase (NamPRT) catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide D-ribonucleotide (NMN), an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
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