Compartment:
plasma membrane,
extracellular region
Neuromedin-U receptor 2 binds the neuromedin-U and neuromedin-S. While neuromedin-U is an agonist at both the NMUR1 and NMUR2 subtypes, neuromedin-S is selective for NMUR2, and a more potent agonist for NMUR2 than neuromedin-U.