Search results for NUDT2

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NUDT2 hydrolyses GP4G to GTP, GMP

Identifier: R-HSA-5696197
Species: Homo sapiens
Compartment: mitochondrial matrix
Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (NUDT2) mediates the asymmetrical hydrolysis of P(1),P(4)-bis(5'-guanosyl) tetraphosphate (GP4G) to yield AMP and ATP. GP4G is implicated in the regulation of cellular responses to stress and its hydrolysis could serve as a mechanism by which homeostasis is maintained by preventing its build-up (Thorne et al. 1995, Swarbrick et al. 2005).
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