Search results for PANK4

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Species

Types

Compartments

Search properties

Protein (1 results from a total of 1)

PANK4

Identifier: R-HSA-199227
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: PANK4: Q9NVE7

Reaction (1 results from a total of 1)

PANK4 hydrolyzes PPANT to pantetheine

Identifier: R-HSA-9837419
Species: Homo sapiens
Compartment: cytosol
Cytosolic PANK4 hydrolyzes (R)-4'-phosphopantetheine (PPANT) to pantetheine (Huang et al. 2016). This reaction, coupled to the hydrolysis of CoA-SH mediated by NUDT enzymes, could play a role in rapidly reducing cellular CoA levels in response to changes in requirements for energy metabolism (Naquet et al. 2020).
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