Search results for PILRB
Showing 4 results out of 4
Protein (1 results from a total of 1)
Identifier: R-HSA-2130158
Species:
Homo sapiens
Compartment:
plasma membrane
Primary external reference: UniProt: PILRB:
Q9UKJ0
Set (1 results from a total of 1)
Identifier: R-HSA-8862072
Species:
Homo sapiens
Compartment:
plasma membrane
Reaction (1 results from a total of 1)
Identifier: R-HSA-8862084
Species:
Homo sapiens
Compartment:
plasma membrane
The paired immunoglobulin-like type 2 receptors (PILR) comprise the inhibitory receptor PILRA and the activating receptor PILRB (Shiratori et al. 2004). The inhibitory PILRA is mainly expressed on macrophages, dendritic cells and granulocytes, whereas the activating PILRB is mainly on activated NK cells. Both recognize mouse CD99 as a ligand, but the binding affinity of PILRB is much lower (Tabata et al. 2008). Mouse NK cells expressing PILRB mediate cytotoxicity against CD99-positive target cells, suggesting that this receptor may be involved in NK cell recognition (Shiratori et al. 2004).
Complex (1 results from a total of 1)
Identifier: R-HSA-8862083
Species:
Homo sapiens
Compartment:
plasma membrane
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