Search results for PMM1

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Protein (1 results from a total of 1)

Identifier: R-HSA-532541
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: PMM1: Q92871

Set (1 results from a total of 1)

Identifier: R-HSA-532532
Species: Homo sapiens
Compartment: cytosol

Reaction (6 results from a total of 6)

Identifier: R-HSA-446201
Species: Homo sapiens
Compartment: cytosol
Phosphomannomutases 1 and 2 (PMM1 and PMM2) catalyse the isomerisation of mannose 6-phosphate (Man6P) to mannose 1-phosphate (Man1P) in the cytosol of cells (Wada & Sakamoto 1997, Matthijs et al. 1997). Mutations in the PMM2 gene are one of the causes of Jaeken syndrome. a disease of glycosylation, type CDGIa. (Matthijs et al. 1997b).
Identifier: R-HSA-8955760
Species: Homo sapiens
Compartment: cytosol
1,3-bisphosphoglycerate (1,3BPG) is the first energy rich intermediate of glycolysis. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) utilises 1,3BPG as a phosphate donor to phosphorylate a series of 1-phosphate sugars. Although 5- and 6-phosphate sugars are poor substrates for PGM2L1, glucose 6-phosphate (G6P) is the exception (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008). PGM2L1 complexed with Mg2+ as cofactor, phosphorylates G6P to glucose 1,6-bisphosphate (G1,6BP), a cofactor for phosphomutases and a putative regulator of glycolysis. PGM2L1 is mainly expressed in brain where its activity is particularly high (Maliekal et al. 2007).
Identifier: R-HSA-70427
Species: Homo sapiens
Compartment: cytosol
Cytosolic phosphoglucomutase 1 (PGM1) catalyzes the reversible conversion of glucose 1-phosphate to glucose 6-phosphate. Two PGM isoenzymes, both monomers, have been identified. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Parrington et al. 1968; Putt et al. 1993). PGM2 also has substantial phosphopentomutase activity and its primary physiological in normal tissues in vivo is not clear. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) also possesses phosphoglucomutase activity (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008).
Identifier: R-HSA-9638125
Species: Homo sapiens
Compartment: cytosol
Cytosolic phosphoglucomutase 1 (PGM1) catalyzes the reversible conversion of glucose 1-phosphate to glucose 6-phosphate. Two PGM isoenzymes, both monomers, have been identified. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Parrington et al. 1968; Putt et al. 1993). PGM2 also has substantial phosphopentomutase activity and its primary physiological in normal tissues in vivo is not clear. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) also possesses phosphoglucomutase activity (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008).
Identifier: R-HSA-70272
Species: Homo sapiens
Compartment: cytosol
Cytosolic phosphoglucomutase (PGM) catalyses the reversible conversion of glucose 6-phosphate (G6P) to glucose 1-phosphate (G1P) (Drago et al. 1991). Two PGM isoenzymes, both monomers, have been identified which both require Mg2+ as cofactor. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Parrington et al. 1968; Putt et al. 1993). PGM2 also has substantial phosphopentomutase activity (Maliekal et al. 2007) and its primary physiological in normal tissues in vivo is not clear. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) also possesses phosphoglucomutase activity (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008).
Identifier: R-HSA-9638127
Species: Homo sapiens
Compartment: cytosol
Cytosolic phosphoglucomutase1 (PGM1) catalyses the reversible conversion of glucose 6-phosphate (G6P) to glucose 1-phosphate (G1P) (Drago et al. 1991). Two PGM isoenzymes, both monomers, have been identified which both require Mg2+ as cofactor. PGM1 is the major form found in most tissues except erythrocytes, where PGM2 is abundant (March et al. 1993; Parrington et al. 1968; Putt et al. 1993). PGM2 also has substantial phosphopentomutase activity (Maliekal et al. 2007) and its primary physiological in normal tissues in vivo is not clear. Cytosolic glucose 1,6-bisphosphate synthase (PGM2L1) also possesses phosphoglucomutase activity (Maliekal et al. 2007, Veiga-da-Cunha et al. 2008).
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