Search results for PRKAR2A

Showing 5 results out of 5

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Species

Types

Compartments

Reaction types

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Species

Types

Compartments

Reaction types

Search properties

Protein (2 results from a total of 2)

Identifier: R-HSA-57840
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: PRKAR2A: P13861
Identifier: R-HSA-5610412
Species: Homo sapiens
Compartment: ciliary base
Primary external reference: UniProt: PRKAR2A: P13861

Reaction (1 results from a total of 1)

Identifier: R-HSA-9668558
Species: Homo sapiens
Compartment: cytosol
NBEA (neurobeachin) binds to the regulatory subunit of PKA, PRKAR2A (PKA RIIalpha). This binding may be involved in localizing PKA to specific subcellular regions, e.g. postsynaptic density in neurons (Wang et al. 2000), but the experimental evidence is not conclusive. Mice that are heterozygous for NBEA gene knockout have NBEA haploinsufficiency and show aberrant PKA activity and changes in platelet morphology (Nuytens et al. 2013). PRKAR2A-binding domain of NBEA is not essential for NBEA-mediated targeting of glutamate and GABA receptors to the synapse (Farzana et al. 2016).

Complex (2 results from a total of 2)

Identifier: R-HSA-9010715
Species: Homo sapiens
Compartment: cytosol
Identifier: R-HSA-9010716
Species: Homo sapiens
Compartment: plasma membrane
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