Search results for SH3GL2

Showing 6 results out of 6

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Species

Types

Compartments

Search properties

Protein (4 results from a total of 4)

Identifier: R-HSA-182958
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: SH3GL2: Q99962
Identifier: R-HSA-177495
Species: Homo sapiens
Compartment: plasma membrane
Primary external reference: UniProt: SH3GL2: Q99962
Identifier: R-HSA-2130629
Species: Homo sapiens
Compartment: clathrin-coated endocytic vesicle membrane
Primary external reference: UniProt: SH3GL2: Q99962
Identifier: R-HSA-351189
Species: Homo sapiens
Compartment: Golgi membrane
Primary external reference: UniProt: SH3GL2: Q99962

Complex (1 results from a total of 1)

Identifier: R-HSA-8867741
Species: Homo sapiens
Compartment: cytosol

Reaction (1 results from a total of 1)

Identifier: R-HSA-8875482
Species: Homo sapiens
Compartment: cytosol, plasma membrane
CBL recruits the complex of SH3KBP1 (CIN85) and endophilin to the activated MET receptor. While CIN85 and endophilin are not involved in CBL tyrosine phosphorylation by activated MET and CBL-mediated MET ubiquitination, they are required for internalization and degradation of the activated MET receptor (Petrelli et al. 2002). CIN85 likely functions as a homotetramer (Watanabe et al. 2000). Endophilin A1 (SH3GL2), A2 (SH3GL1) and A3 (SH3GL3), which function as homodimers, can all be recruited to the activated MET receptor, with SH3GL3 being the most extensively studied (Petrelli et al. 2002).
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